Paul Desmond

Factors that predict a poor response to radiofrequency ablation for Barrett's oesophagus with dysplasia

Edward H Tsoi, Georgina Cameron, Richard Williams, Paul Desmond, Andrew Taylor

Journal article  |  2020  |  ANZ Journal of Surgery

Diffuse endoscopically visible, predominantly low grade dysplasia in Barrett's esophagus (with video)

Edward H Tsoi, Sasha Fehily, Richard Williams, Paul Desmond, Andrew Taylor

Journal article  |  2019  |  Endoscopy International Open

Malignancy risk in gastric ulcers: A multi-centre retrospective study

Linda Yang, Imogen Hartley, Alexander Thompson, Paul Desmond, Andrew Taylor, Alan Moss, Bronte Holt

Conference Proceedings  |  2019  |  JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Endoscopic features of buried Barrett's mucosa: visible to the trained eye?

Linda Yang, Bronte Holt, Richard Williams, Edward Tsoi, Georgina Cameron, Paul Desmond, Andrew Taylor

Conference Proceedings  |  2019  |  JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Quantifying Early Gastric Cancer in Australia: What is the potential need for gastric ESD in the West?

Linda Yang, Andrew Taylor, Alexander Thompson, Paul Desmond, Bronte Holt

Conference Proceedings  |  2019  |  JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

'Teach-back' is a simple communication tool that improves disease knowledge in people with chronic hepatitis B - a pilot randomized controlled study

Sophie Tran, Gabrielle Bennett, Jacqui Richmond, Nguyen Tin, Marno Ryan, Thai Hong, Jessica Howell, Barbara Demediuk, Paul Desmond, Sally Bell, Alexander Thompson

Journal article  |  2019  |  BMC Public Health

BACKGROUND: The low diagnosis rate and poor access to clinical care among people with CHB is a major barrier to reducing HBV-relat..

Nurse-led, protocol-driven screening for hepatitis B virus before initiating biological therapy for chronic inflammatory disease is very effective

I Urbano, A Sim, S Oon, J Luong, F Lai, M Sullivan, P Foley, S Anderson, D Courtney, A Macdonald, T Samyue, S Fry, A Stanley, J Ding, W Connell, M Lust, J Schulberg, C Basnayake, M Kamm, E Flanagan, et al.

Conference Proceedings  |  2019  |  JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Eliminating hepatitis C by 2030: Hospital presentation provides opportunities for engagement and treatment of marginalized individuals with chronic hepatitis C

E Freeman, K New, S Glasgow, L Stothers, C Croagh, P Desmond, B Demediuk, J Holmes, T Hong, J Howell, M Ryan, J Doyle, A Thompson

Conference Proceedings  |  2019  |  JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Outcomes of treatment for hepatitis C in prisoners using a nurse-led, statewide model of care

Timothy Papaluca, Lucy McDonald, Anne Craigie, Annabelle Gibson, Paul Desmond, Darren Wong, Rebecca Winter, Nick Scott, Jessica Howell, Joseph Doyle, Alisa Pedrana, Andrew Lloyd, Mark Stoove, Margaret Hellard, David Iser, Alexander Thompson

Journal article  |  2019  |  Journal of Hepatology

Low rate of treatment uptake amongst recently released prisoners with active HCV infection

Tim Papaluca, George Tambakis, Anne Craigie, Lucy Mcdonald, Amy Edwards, David Iser, Jessica Howell, Paul Desmond, Mark Stoove, Margaret Hellard, Joseph Doyle, Alexander Thompson

Conference Proceedings  |  2019  |  Journal of Hepatology

Surveillance improves survival of patients with hepatocellular carcinoma: a prospective population-based study

Thai P Hong, Paul J Gow, Michael Fink, Anouk Dev, Stuart K Roberts, Amanda Nicoll, John S Lubel, Ian Kronborg, Niranjan Arachchi, Marno Ryan, William W Kemp, Virginia Knight, Vijaya Sundararajan, Paul Desmond, Alexander J Thompson, Sally J Bell

Journal article  |  2018  |  Medical Journal of Australia

Salvage Therapy with Sofosbuvir, Elbasvir, Grazoprevir and Ribavirin for Daa Non-Responders - High Efficacy in GT3 and GT1/4 HCV Infection

Tim Papaluca, Susanne Glasgow, Kate New, Anne Craigie, Lucy McDonald, Lisa Stothers, David Iser, Paul Desmond, Sally Bell, Barbara Demediuk, Kumar Visvanathan, Marno Ryan, Jessica Howell, Thai Hong, Catherine Croagh, Marie Sinclair, Peter W Angus, Niranjan Arachchi, Jacinta O'Keefe, Scott Bowden, et al.

Conference Proceedings  |  2018  |  HEPATOLOGY

Outcomes of the First 44 Patients at 48 Weeks in the HBV-STOP Study, a Prospective Study of Nucleot(s)Ide Analogue Discontinuation in Non-Cirrhotic Hbeag-Negative Chronic Hepatitis B Patients Who Have Achieved Long Term Virological Suppression

Samuel Hall, Gareth Burns, Miriam T Levy, John S Lubel, Amanda Nicoll, Gail Matthews, Paul V Desmond, William Sievert, Scott Bowden, Stephen Locarnini, Kumar Visvanathan, Alexander Thompson

Conference Proceedings  |  2018  |  HEPATOLOGY

The e Antigen Is an Interferon Resistance Protein That Allows the Hepatitis B Virus to Evade the Early Immune Response.

Zina Valaydon, Gregor Ebert, Liana Mackiewicz, Simon Preston, Paul V Desmond, Vitina Sozzi, Peter Revill, Alexander JV Thompson, Marc Pellegrini

Conference Proceedings  |  2018  |  HEPATOLOGY

In hepatitis C patients with cirrhosis who achieve SVR with treatment, reduction in transient elastography measures does not translate to reduced risk of hepatocellular carcinoma: A prospective cohort study

J Howell, T Papaluca, S Glasgow, K New, T Hong, J Snell, D Iser, M Ryan, S Bell, P Desmond, SLCY Mei, C Croagh, T Nguyen, Z Valaydon, G Shaw, B Demediuk, L Mcdonald, A Craigie, L Stothers, M Lust, et al.

Conference Proceedings  |  2018  |  Journal of Hepatology

"B in IT" - a community-based model for the management of hepatitis B patients in primary care clinics using a novel web-based clinical tool.

Debra A O'Leary, Eleanor Cropp, David Isaac, Paul V Desmond, Sally Bell, Tin Nguyen, Darren Wong, Jessica Howell, Jacqui Richmond, Jenny O'Neill, Alexander J Thompson

Journal article  |  2018  |  Hepatology, Medicine and Policy

Background: The current model of care for the treatment of chronic hepatitis B (CHB) in Australia is through specialist Hepatology..

Sustained virological response halts fibrosis progression: A long-term follow-up study of people with chronic hepatitis C infection

Swee Lin G Chen Yi Mei, Alexander J Thompson, Britt Christensen, Georgina Cunningham, Lucy McDonald, Sally Bell, David Iser, Tin Nguyen, Paul V Desmond

Journal article  |  2017  |  PLOS ONE

Five-year efficacy and safety of tenofovir-based salvage therapy for patients with chronic hepatitis B who previously failed LAM/ADV therapy

Lucy Lim, Alexander Thompson, Scott Patterson, Jacob George, Simone Strasser, Alice Lee, William Sievert, Amanda Nicoll, Paul Desmond, Stuart Roberts, Kaye Marion, Scott Bowden, Stephen Locarnini, Peter Angus

Journal article  |  2017  |  Liver International

Efficacy and safety of tenofovir in chronic hepatitis B: Australian real world experience

Grace C Lovett, Tin Nguyen, David M Iser, Jacinta A Holmes, Robert Chen, Barbara Demediuk, Gideon Shaw, Sally J Bell, Paul V Desmond, Alexander J Thompson

Journal article  |  2017  |  World Journal of Hepatology

The role of tumour necrosis factor in hepatitis B infection: Jekyll and Hyde

Zina Valaydon, Marc Pellegrini, Alexander Thompson, Paul Desmond, Peter Revill, Gregor Ebert

Journal article  |  2016  |  Clinical & Translational Immunology

Toll-like Receptor Expression and Signaling in Peripheral Blood Mononuclear Cells Correlate With Clinical Outcomes in Acute Hepatitis C Virus Infection

Swee Lin G Chen Yi Mei, Jodie Burchell, Narelle Skinner, Rosie Millen, Gail Matthews, Margaret Hellard, Gregory J Dore, Paul V Desmond, Vijaya Sundararajan, Alexander J Thompson, Kumar Visvanathan, Joe Sasadeusz

Journal article  |  2016  |  Journal of Infectious Diseases

Recurrent intestinal metaplasia at the gastroesophageal junction following endoscopic eradication of dysplastic Barrett's esophagus may not be benign

Georgina R Cameron, Paul V Desmond, Chatura S Jayasekera, Francesco Amico, Richard Williams, Finlay A Macrae, Andrew CF Taylor

Journal article  |  2016  |  Endoscopy International Open

Influence of food and lifestyle on the risk of developing inflammatory bowel disease

O Niewiadomski, C Studd, J Wilson, J Williams, C Hair, R Knight, E Prewett, P Dabkowski, S Alexander, B Allen, D Dowling, W Connell, P Desmond, S Bell

Journal article  |  2016  |  Internal Medicine Journal

Cost-effectiveness of Crohn's disease post-operative care

Emily K Wright, Michael A Kamm, Peter Dr Cruz, Amy L Hamilton, Kathryn J Ritchie, Sally J Bell, Steven J Brown, William R Connell, Paul V Desmond, Danny Liew

Journal article  |  2016  |  World journal of gastroenterology

Novel Population-Based Study Finding Higher Than Reported Hepatocellular Carcinoma Incidence Suggests an Updated Approach Is Needed

Thai P Hong, Paul Gow, Michael Fink, Anouk Dev, Stuart Roberts, Amanda Nicoll, John Lubel, Ian Kronborg, Niranjan Arachchi, Marno Ryan, William Kemp, Virginia Knight, Helen Farrugia, Vicky Thursfield, Paul Desmond, Alexander J Thompson, Sally Bell

Journal article  |  2016  |  Hepatology

Liver stiffness plus platelet count can be used to exclude high-risk oesophageal varices

Nik S Ding, Nguyen Tin, David M Iser, Thai Hong, Emma Flanagan, Avelyn Wong, Lauren Luiz, Jonathan YC Tan, James Fulforth, Jacinta Holmes, Marno Ryan, Sally J Bell, Paul V Desmond, Stuart K Roberts, John Lubel, William Kemp, Alexander J Thompson

Journal article  |  2016  |  Liver International

Never underestimate inflammatory bowel disease: High prevalence rates and confirmation of high incidence rates in Australia

Corrie Studd, Georgina Cameron, Lauren Beswick, Ross Knight, Christopher Hair, John McNeil, Paul Desmond, Jarrad Wilson, Wiliam Connell, Sally Bell

Journal article  |  2016  |  Journal of Gastroenterology and Hepatology

Health Care Cost Analysis in a Population-based Inception Cohort of Inflammatory Bowel Disease Patients in the First Year of Diagnosis

Olga Niewiadomski, Corrie Studd, Christopher Hair, Jarrad Wilson, John McNeill, Ross Knight, Emily Prewett, Paul Dabkowski, Damian Dowling, Sina Alexander, Benjamin Allen, Mark Tacey, William Connell, Paul Desmond, Sally Bell

Journal article  |  2015  |  Journal of Crohn's and Colitis

Efficacy of thiopurines and adalimumab in preventing Crohn's disease recurrence in high-risk patients - a POCER study analysis

P De Cruz, MA Kamm, AL Hamilton, KJ Ritchie, EO Krejany, A Gorelik, D Liew, L Prideaux, IC Lawrance, JM Andrews, PA Bampton, S Jakobovits, TH Florin, PR Gibson, H Debinski, RB Gearry, FA Macrae, RW Leong, I Kronborg, G Radford-Smith, et al.

Journal article  |  2015  |  Alimentary pharmacology & therapeutics

Injecting risk behaviours following treatment for hepatitis C virus infection among people who inject drugs: The Australian Trial in Acute Hepatitis C

Maryam Alavi, Tim Spelman, Gail V Matthews, Paul S Haber, Carolyn Day, Ingrid van Beek, Nick Walsh, Barbara Yeung, Julie Bruneau, Kathy Petoumenos, Kate Dolan, John M Kaldor, Gregory J Dore, Margaret Hellard, Jason Grebely

Journal article  |  2015  |  International Journal of Drug Policy

Prospective population-based cohort of inflammatory bowel disease in the biologics era: Disease course and predictors of severity

Olga Niewiadomski, Corrie Studd, Chris Hair, Jarrad Wilson, Nik S Ding, Neel Heerasing, Alvin Ting, John McNeill, Ross Knight, John Santamaria, Emily Prewett, Paul Dabkowski, Damian Dowling, Sina Alexander, Ben Allen, Benjamin Popp, William Connell, Paul Desmond, Sally Bell

Journal article  |  2015  |  Journal of Gastroenterology and Hepatology

The relationships between IFNL4 genotype, intrahepatic interferon-stimulated gene expression and interferon treatment response differs in HCV-1 compared with HCV-3

JA Holmes, M Congiu, S Bonanzinga, MK Sandhu, YH Kia, SJ Bell, T Nguyen, DM Iser, K Visvanathan, W Sievert, DS Bowden, PV Desmond, AJ Thompson

Journal article  |  2015  |  Alimentary Pharmacology & Therapeutics

Effect of Intestinal Resection on Quality of Life in Crohn's Disease

Emily K Wright, Michael A Kamm, Peter De Cruz, Amy L Hamilton, Kathryn J Ritchie, Efrosinia O Krejany, Alexandra Gorelik, Danny Liew, Lani Prideaux, Ian C Lawrance, Jane M Andrews, Peter A Bampton, Miles P Sparrow, Timothy H Florin, Peter R Gibson, Henry Debinski, Richard B Gearry, Finlay A Macrae, Rupert W Leong, Ian Kronborg, et al.

Journal article  |  2015  |  Journal of Crohn's and Colitis

Measurement of Fecal Calprotectin Improves Monitoring and Detection of Recurrence of Crohn's Disease After Surgery

Emily K Wright, Michael A Kamm, Peter De Cruz, Amy L Hamilton, Kathryn J Ritchie, Efrosinia O Krejany, Steven Leach, Alexandra Gorelik, Danny Liew, Lani Prideaux, Ian C Lawrance, Jane M Andrews, Peter A Bampton, Simon L Jakobovits, Timothy H Florin, Peter R Gibson, Henry Debinski, Finlay A Macrae, Douglas Samuel, Ian Kronborg, et al.

Journal article  |  2015  |  Gastroenterology

Non-physician endoscopists: A systematic review

Maximilian Stephens, Luke F Hourigan, Mark Appleyard, George Ostapowicz, Mark Schoeman, Paul V Desmond, Jane M Andrews, Michael Bourke, David Hewitt, David A Margolin, Gerald J Holtmann

Journal article  |  2015  |  World Journal of Gastroenterology

Crohn's disease management after intestinal resection: a randomised trial

Peter De Cruz, Michael A Kamm, Amy L Hamilton, Kathryn J Ritchie, Efrosinia O Krejany, Alexandra Gorelik, Danny Liew, Lani Prideaux, Ian C Lawrance, Jane M Andrews, Peter A Bampton, Peter R Gibson, Miles Sparrow, Rupert W Leong, Timothy H Florin, Richard B Gearry, Graham Radford-Smith, Finlay A Macrae, Henry Debinski, Warwick Selby, et al.

Journal article  |  2015  |  The Lancet

Genotypes and viral variants in chronic hepatitis B: A review of epidemiology and clinical relevance

Catherine MN Croagh, Paul V Desmond, Sally J Bell

Journal article  |  2015  |  World Journal of Hepatology

Treatment of refractory stomal variceal haemorrhage with embolisation and sclerosis

Z Valaydon, P Desmond

Journal article  |  2015  |  Internal Medicine Journal

Detection and staging of esophageal cancers within Barrett's esophagus is improved by assessment in specialized Barrett's units

Georgina R Cameron, Chatura S Jayasekera, Richard Williams, Finlay A Macrae, Paul V Desmond, Andrew C Taylor

Journal article  |  2014  |  Gastrointestinal Endoscopy

A magnetic resonance spectroscopy (H-1 MRS) investigation into brain metabolite correlates of ability emotional intelligence

A Timoshanko, P Desmond, DA Camfield, LA Downey, C Stough

Journal article  |  2014  |  Personality and Individual Differences

DOUBLE BALLOON ENTEROSCOPY - A SINGLE AUSTRALIAN TERTIARY CENTRE EXPERIENCE

P Sattianayagam, P Desmond, A Taylor

Conference Proceedings  |  2014  |  Gut

ITPA Genotype Protects Against Anemia During Peginterferon and Ribavirin Therapy but Does Not Influence Virological Response

Jacinta A Holmes, Stuart K Roberts, Rachel J Ali, Gregory J Dore, William Sievert, Geoffrey W McCaughan, Darrell H Crawford, Wendy S Cheng, Martin D Weltman, Sara Bonanzinga, Kumar Visvanathan, Vijaya Sundararajan, Paul V Desmond, D Scott Bowden, Gail V Matthews, Alexander J Thompson

Journal article  |  2014  |  Hepatology

PROLONGED OVERT OBSCURE GASTROINTESTINAL BLEEDING - A "REAL WORLD" EXPERIENCE

P Sattianayagam, P Desmond, A Taylor

Conference Proceedings  |  2014  |  Gut

Perspectives of paediatric and adult gastroenterologists on transfer and transition care of adolescents with inflammatory bowel disease

EK Wright, J Williams, JM Andrews, AS Day, RB Gearry, P Bampton, D Moore, D Lemberg, R Ravikumaran, J Wilson, P Lewindon, G Radford-Smith, J Rosenbaum, A Catto-Smith, PV Desmond, WR Connell, D Cameron, G Alex, SJ Bell, P De Cruz

Journal article  |  2014  |  INTERNAL MEDICINE JOURNAL

Retreatment of HCV with ABT-450/r-Ombitasvir and Dasabuvir with Ribavirin

Stefan Zeuzem, Ira M Jacobson, Tolga Baykal, Rui T Marinho, Fred Poordad, Marc Bourliere, Mark S Sulkowski, Heiner Wedemeyer, Edward Tam, Paul Desmond, Donald M Jensen, Adrian M Di Bisceglie, Peter Varunok, Tarek Hassanein, Junyuan Xiong, Tami Pilot-Matias, Barbara DaSilva-Tillmann, Lois Larsen, Thomas Podsadecki, Barry Bernstein

Journal article  |  2014  |  New England Journal of Medicine

A prospective population-based natural history registry of newly diagnosed IBD identifies high rates of severe disease and immunomodulator use after 1 year

O Niewiadomski, J Ding, J McNeill, K Ross, P Dabkowski, C Hair, E Prewett, S Alexander, D Dowling, B Popp, B Allen, J Wilson, C Studd, P Desmond, W Connell, S Bell

Conference Proceedings  |  2014  |  Journal of Crohn's and Colitis

Endoscopic submucosal dissection: Experience in an Australian tertiary center

PT Sattianayagam, PV Desmond, C Jayasekera, RY Chen

Journal article  |  2014  |  Annals of Gastroenterology

Inflammatory bowel disease cancer surveillance in a tertiary referral hospital: attitudes and practice

EC Verschuren, DE Ong, MA Kamm, PV Desmond, M Lust

Journal article  |  2014  |  Internal Medicine Journal

Impact of Ethnicity, Geography, and Disease on the Microbiota in Health and Inflammatory Bowel Disease

Lani Prideaux, Seungha Kang, Josef Wagner, Michael Buckley, Jackie E Mahar, Peter De Cruz, Zhonghui Wen, Liping Chen, Bing Xia, Daniel R van Langenberg, Trevor Lockett, Siew C Ng, Joseph JY Sung, Paul Desmond, Chris McSweeney, Mark Morrison, Carl D Kirkwood, Michael A Kamm

Journal article  |  2013  |  Inflammatory Bowel Diseases

Hepatitis B virus splicing is enhanced prior to development of hepatocellular carcinoma

Julianne Bayliss, Lucy Lim, Alexander JV Thompson, Paul Desmond, Peter Angus, Stephen Locarnini, Peter A Revill

Journal article  |  2013  |  Journal of Hepatology

Psychological Well-Being and Quality of Life in Crohn's Disease Patients With an Ostomy A Preliminary Investigation

Simon R Knowles, Jarrad Wilson, Annette Wilkinson, William Connell, Michael Salzberg, David Castle, Paul Desmond, Michael A Kamm

Journal article  |  2013  |  Journal of WOCN - Wound Ostomy and Continence Nursing

High incidence of hepatocellular carcinoma in melbourne: Results from a population-based epidemiological study

T Hong, A Thompson, P Gow, M Fink, M Ryan, A Dev, I Kronborg, N Arachchi, J Lubel, A Nicoll, S Roberts, P Desmond, S Bell

Conference Proceedings  |  2013  |  JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

IFNL4 genotype is in strong linkage disequilibrium with IL28B genotype and predicts peg-interferon plus ribavirin treatment outcomes: an independent validation study

Jacinta A Holmes, Mario Congiu, Sara Bonanzinga, Manjeet K Sandhu, Sally Bell, Nguyen Tin, David M Iser, Kumar Visvanathan, William Sievert, Scott Bowden, Paul V Desmond, Alexander J Thompson

Conference Proceedings  |  2013  |  HEPATOLOGY

Longitudinal observation of viral load changes in untreated HBeAg negative chronic hepatitis B

Catherine MN Croagh, Sally J Bell, Robert Y Chen, Stephen Locarnini, Paul V Desmond

Journal article  |  2013  |  Acta Gastro-Enterologica Belgica

Chromoendoscopy versus Narrow Band Imaging for Colonic Surveillance in Inflammatory Bowel Disease

Marios Efthymiou, Patrick B Allen, Andrew CF Taylor, Paul V Desmond, Chatura Jayasakera, Peter De Cruz, Michael A Kamm

Journal article  |  2013  |  Inflammatory Bowel Diseases

Reply to: "Might some of the beneficial effects of the Mediterranean diet on non-alcoholic fatty liver disease be mediated by reduced iron stores?"

Marno C Ryan, Paul Desmond, Andrew Wilson

Journal article  |  2013  |  Journal of Hepatology

The Mediterranean diet improves hepatic steatosis and insulin sensitivity in individuals with non-alcoholic fatty liver disease

Marno C Ryan, Catherine Itsiopoulos, Tania Thodis, Glenn Ward, Nicholas Trost, Sophie Hofferberth, Kerin O'Dea, Paul V Desmond, Nathan A Johnson, Andrew M Wilson

Journal article  |  2013  |  JOURNAL OF HEPATOLOGY

Bortezomib monotherapy in patients with multiple myeloma is associated with reactivation of hepatitis B

R Goldberg, E Smith, S Bell, A Thompson, PV Desmond

Journal article  |  2013  |  Internal Medicine Journal

The Mediterranean diet improves hepatic steatosis and insulin sensitivity in individuals with non-alcoholic fatty liver disease

MC Ryan, C Itsiopoulos, T Thodis, G Ward, N Trost, S Hofferberth, K O'Dea, PV Desmond, NA Johnson, AM Wilson

Journal article  |  2013  |  Journal of Hepatology

Erratum: Added value of narrow band imaging and confocal laser endomicroscopy in detecting Barrett's esophagus neoplasia (Endoscopy (2012) 44 (1089-1095))

C Jayasekera, ACF Taylor, PV Desmond, F Macrae, R Williams

Journal article  |  2013  |  Endoscopy

IL28B genotype is not useful for predicting treatment outcome in Asian chronic hepatitis B patients treated with pegylated interferon-alpha

Jacinta A Holmes, Nguyen Tin, Dilip Ratnam, Neel M Heerasing, Jane V Tehan, Sara Bonanzinga, Anouk Dev, Sally Bell, Stephen Pianko, Robert Chen, Kumar Visvanathan, Rachel Hammond, David Iser, Ferry Rusli, William Sievert, Paul V Desmond, D Scott Bowden, Alexander J Thompson

Journal article  |  2013  |  JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

ITPA ACTIVITY PREDICTS Hb DECLINE AFTER FOUR WEEKS OF PI TRIPLE THERAPY, REGARDLESS OF PREVIOUS TREATMENT OR NAIVE STATUS AND FIBROSIS: A MULTICENTER REAL-LIFE EXPERIENCE

A Mangia, PJ Clark, V Piazzolla, R Santoro, JA Holmes, L Mottola, M Ripoli, D Iser, T Nguyen, SJ Bell, PV Desmond, D Petruzzellis, K Patel, AJ Muir, AJ Thompson

Conference Proceedings  |  2013  |  JOURNAL OF HEPATOLOGY

Ileocaecal tuberculosis: re-emergence in developed countries

MCS Choy, B Christensen, PV Desmond

Journal article  |  2013  |  Internal Medicine Journal

Development and validation of a patient-reported disability measurement tool for patients with inflammatory bowel disease

PB Allen, MA Kamm, L Peyrin-Biroulet, C Studd, C Mc Dowell, BCM Allen, WR Connell, PP De Cruz, SJ Bell, RP Elliot, S Brown, PV Desmond, M Lemann, J-F Colombel

Journal article  |  2013  |  Alimentary Pharmacology and Therapeutics

Postoperative recurrence of Crohn's disease: impact of endoscopic monitoring and treatment step-up

P De Cruz, M-P Bernardi, MA Kamm, PB Allen, L Prideaux, J Williams, MJ Johnston, J Keck, R Brouwer, A Heriot, R Woods, S Brown, SJ Bell, R Elliott, WR Connell, PV Desmond

Journal article  |  2013  |  Colorectal Disease

Androgenic-anabolic steroid drug-induced liver injury

NS Ding, P De Cruz, L Lim, A Thompson, P Desmond

Journal article  |  2013  |  Internal Medicine Journal

Treatment of Chronic Viral Hepatitis B and Drug Resistant Variants

Tin Nguyen, Paul Desmond, Stephen Locarnini

Book Chapter  |  2013

Prescribing in patients with abnormal liver function tests

Emily Smith, Paul Desmond

Journal article  |  2013  |  Australian Family Physician

Prescribing in patients with abnormal liver function tests

E Smith, P Desmond

Journal article  |  2013  |  Australian Family Physician

Added value of narrow band imaging and confocal laser endomicroscopy in detecting Barrett's esophagus neoplasia

C Jayasekera, ACF Taylor, PV Desmond, F Macrae, R Williams

Journal article  |  2012  |  Endoscopy

SINGLE-01: a randomized, controlled trial comparing the efficacy and depth of insertion of single- and double-balloon enteroscopy by using a novel method to determine insertion depth

Marios Efthymiou, Paul V Desmond, Gregor Brown, Richard La Nauze, Arthur Kaffes, Tee Joo Chua, Andrew CF Taylor

Journal article  |  2012  |  Gastrointestinal Endoscopy

Does IL28B genotyping still have a role in the era of direct-acting antiviral therapy for chronic hepatitis C infection?

JA Holmes, PV Desmond, AJ Thompson

Journal article  |  2012  |  Journal of Viral Hepatitis

Tenofovir Rescue Therapy Achieves Long-Term Suppression of HBV Replication in Patients with Multi-Drug Resistant HBV: 4 Year Follow-Up of the TDF109 Cohort

Lucy Y Lim, Scott Patterson, Jacob George, Simone I Strasser, Alice U Lee, William Sievert, Amanda J Nicoll, Stuart K Roberts, Paul V Desmond, Scott Bowden, Alexander J Thompson, Stephen Locarnini, Peter W Angus

Conference Proceedings  |  2012  |  HEPATOLOGY

High incidence and prevalence of inflammatory bowel disease in Victoria; a prospective, observational, population-based Australian epidemiology study

Corrie Studd, Paul Desmond, William Connell, John Mcneil, Ross E Knight, Georgina Cameron, Lauren Beswick, Christopher Hair, Tiffany Symes, Jarrad Wilson, Sally Bell

Journal article  |  2012  |  Journal of Gastroenterology and Hepatology

The association of IL28B genotype with peginterferon-alpha/ribavirin ( PR) treatment outcome and liver interferon-stimulated gene (ISG) expression is determined by HCV genotype

Jacinta A Holmes, Mario Congiu, Sara Bonanazinga, Manjeet K Sandhu, Yin H Kia, Sally Bell, Kumar Visvanathan, William Sievert, Scott Bowden, Paul V Desmond, Alexander J Thompson

Conference Proceedings  |  2012  |  HEPATOLOGY

Tenofovir rescue therapy achieves long-term suppression of HBV replication in multi-drug resistant HBV patients: 4 year follow-up of the TDF109 cohort

Lucy Lim, Scott J Patterson, James M Trauer, Jacob George, Simone Strasser, Alice Lee, William Sievert, Amanda Nicoll, Stuart Roberts, Paul Desmond, D Scott Bowden, Alex Thompson, Stephen Locarnini, Peter Angus

Journal article  |  2012  |  JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

IL28B: Current and future use

SG Chen Yi Mei, PV Desmond, AJ Thompson

Journal article  |  2012  |  Current Hepatitis Reports

Comparison of clinical characteristics and management of inflammatory bowel disease in Hong Kong versus Melbourne

Lani Prideaux, Michael A Kamm, Peter De Cruz, James Williams, Sally J Bell, William R Connell, Steven J Brown, Mark Lust, Paul V Desmond, Heyson Chan, Dorothy KL Chow, Justin CY Wu, Rupert W Leong, Joseph J Sung, Francis KL Chan, Siew C Ng

Journal article  |  2012  |  Journal of Gastroenterology and Hepatology

Effect of pegylated interferon-alpha-2a treatment on mental health during recent hepatitis C virus infection

Maryam Alavi, Jason Grebely, Gail V Matthews, Kathy Petoumenos, Barbara Yeung, Carolyn Day, Andrew R Lloyd, Ingrid Van Beek, John M Kaldor, Margaret Hellard, Gregory J Dore, Paul S Haber

Journal article  |  2012  |  Hepatology

Cluster of 4 cases of esophageal squamous cell cancer developing in adults with surgically corrected esophageal atresia-time for screening to start

Chatura S Jayasekera, Paul V Desmond, Jacinta A Holmes, Mathew Kitson, Andrew CF Taylor

Journal article  |  2012  |  Journal of Pediatric Surgery

Postoperative recurrent luminal Crohn's Disease: A systematic review

Peter De Cruz, Michael A Kamm, Lani Prideaux, Patrick B Allen, Paul V Desmond

Journal article  |  2012  |  Inflammatory Bowel Diseases

Methodological considerations in studying natural history of HBeAg-negative and -positive chronic hepatitis B: authors' reply

Catherine MN Croagh, Sally J Bell, Paul V Desmond

Journal article  |  2012  |  Liver International

Methodological considerations in studying natural history of HBeAg-negative and -positive chronic hepatitis B.

Guohong Cai, Wen Yin

Journal article  |  2012  |  Liver International

Endoscopic ultrasound-guided fine needle aspirate: a useful method in the diagnosis of pancreatic tuberculosis

Quetzalihuitl Arroyo Martinez, Peter DeCruz, Aravinth Murugananthan, Paul Desmond, Robert Chen

Journal article  |  2012  |  ANZ Journal of Surgery

IL28B GENOTYPE IS NOT USEFUL FOR PREDICTING TREATMENT OUTCOME IN ASIAN CHRONIC HEPATITIS B (CHB) PATIENTS TREATED WITH PEGYLATED-INTERFERON-A (PIFN)

JA Holmes, T Nguyen, D Ratnam, NM Heerasing, JV Tehan, S Bonanzinga, A Dev, SJ Bell, S Pianko, K Visvanathan, F Rusli, W Sievert, PV Desmond, S Bowden, AJ Thompson

Conference Proceedings  |  2012  |  Journal of Hepatology

Assessment of chronic hepatitis B: the importance of hepatitis B virus DNA testing

CMN Croagh, SJ Bell, S Locarnini, PV Desmond

Journal article  |  2012  |  Internal Medicine Journal

Viral Adaptation to Host Immune Responses Occurs in Chronic Hepatitis B Virus (HBV) Infection, and Adaptation Is Greatest in HBV e Antigen-Negative Disease

Christopher P Desmond, Silvana Gaudieri, Ian R James, Katja Pfafferott, Abha Chopra, George K Lau, Jennifer Audsley, Caroline Day, Sarah Chivers, Adam Gordon, Peter A Revill, Scott Bowden, Anna Ayres, Paul V Desmond, Alexander J Thompson, Stuart K Roberts, Stephen A Locarnini, Simon A Mallal, Sharon R Lewin

Journal article  |  2012  |  JOURNAL OF VIROLOGY

Noninvasive Imaging of the Small Bowel in Crohn's Disease: The Final Frontier

Patrick B Allen, Peter De Cruz, Wai Kit Lee, Stuart Taylor, Paul V Desmond, Michael A Kamm

Journal article  |  2011  |  Inflammatory Bowel Diseases

No increase in the expression of key unfolded protein response genes in HCV genotype 3 patients with severe steatosis

Mario Congiu, Marno C Ryan, Paul V Desmond

Journal article  |  2011  |  Virus Research

Redefining Baseline Demographics: The Role of Genetic Testing in Hepatitis C Virus Infection

Jacinta A Holmes, Paul V Desmond, Alexander J Thompson

Journal article  |  2011  |  Clinics in Liver Disease

Value of fecal occult blood test as a screening test before capsule endoscopy

Marios Efthymiou, Patrick B Allen, Chatura Jayasekera, Paul V Taylor, Andrew CF Taylor

Journal article  |  2011  |  European Journal of Gastroenterology & Hepatology

Biopsy forceps is inadequate for the resection of diminutive polyps

M Efthymiou, ACF Taylor, PV Desmond, PB Allen, RY Chen

Journal article  |  2011  |  Endoscopy

Endoscopic advances in the treatment of dysplastic Barrett oesophagus - should HALO be canonised or do we need more evidence?

Chatura S Jayasekera, Finlay A Macrae, Paul V Desmond, Andrew CF Taylor

Journal article  |  2011  |  Medical Journal of Australia

Expression of common housekeeping genes is affected by disease in human hepatitis C virus-infected liver

Mario Congiu, John L Slavin, Paul V Desmond

Journal article  |  2011  |  Liver International

Tenofovir disoproxil fumarate rescue therapy following failure of both lamivudine and adefovir dipivoxil in chronic hepatitis B

SJ Patterson, J George, SI Strasser, AU Lee, W Sievert, AJ Nicoll, PV Desmond, SK Roberts, S Locarnini, S Bowden, PW Angus

Journal article  |  2011  |  Gut

Increased intrahepatic apoptosis but reduced immune activation in HIV-HBV co-infected patients with advanced immunosuppression

David M Iser, Anchalee Avihingsanon, Naruemon Wisedopas, Alexander J Thompson, Alison Boyd, Gail V Matthews, Stephen A Locarnini, John Slavin, Paul V Desmond, Sharon R Lewin

Journal article  |  2011  |  AIDS

Endoscopic ultrasound guided fine needle aspiration (EUS-FNA) of mediastinal lesions

Tin Q Nguyen, Andrius Kalade, Shyam Prasad, Paul Desmond, Gavin Wright, David Hart, Matthew Conron, Robert Y Chen

Journal article  |  2011  |  ANZ Journal of Surgery

Expression of genes involved in lipogenesis is not increased in patients with HCV genotype 3 in human liver

MC Ryan, PV Desmond, JL Slavin, M Congiu

Journal article  |  2011  |  Journal of Viral Hepatitis

Dysplastic Lesions in Ulcerative Colitis: Changing Paradigms

Patrick B Allen, Michael A Kamm, Peter De Cruz, Paul V Desmond

Journal article  |  2010  |  Inflammatory Bowel Diseases

Potential Role for Interleukin-28B Genotype in Treatment Decision-Making in Recent Hepatitis C Virus Infection

Jason Grebely, Kathy Petoumenos, Margaret Hellard, Gail V Matthews, Vijayaprakash Suppiah, Tanya Applegate, Barbara Yeung, Phillipa Marks, William Rawlinson, Andrew R Lloyd, David Booth, John M Kaldor, Jacob George, Gregory J Dore

Journal article  |  2010  |  Hepatology

UNLABELLED: Polymorphisms in the IL28B (interleukin-28B) gene region are important in predicting outcome following therapy for chr..

Increasing hepatitis B viral load is associated with risk of significant liver fibrosis in HBeAg-negative but not HBeAg-positive chronic hepatitis B

Catherine MN Croagh, Sally J Bell, John Slavin, Yu XG Kong, Robert Y Chen, Stephen Locarnini, Paul V Desmond

Journal article  |  2010  |  Liver International

High Incidence of Inflammatory Bowel Disease in Australia: A Prospective Population-Based Australian Incidence Study

Jarrad Wilson, Christopher Hair, Ross Knight, Anthony Catto-Smith, Sally Bell, Michael Kamm, Paul Desmond, John McNeil, William Connell

Journal article  |  2010  |  Inflammatory Bowel Diseases

Endoscopic ultrasound of pancreatic cystic lesions

Shyam Prasad, Jarrad Wilson, Andrius Kalade, Paul Desmond, Robert Chen

Journal article  |  2010  |  ANZ Journal of Surgery

Serum Hepatitis B Surface Antigen and Hepatitis B e Antigen Titers: Disease Phase Influences Correlation with Viral Load and Intrahepatic Hepatitis B Virus Markers

Alexander JV Thompson, Tin Nguyen, David Iser, Anna Ayres, Kathy Jackson, Margaret Littlejohn, John Slavin, Scott Bowden, Edward J Gane, William Abbott, George KK Lau, Sharon R Lewin, Kumar Visvanathan, Paul V Desmond, Stephen A Locarnini

Journal article  |  2010  |  Hepatology

Coinfection of Hepatic Cell Lines with Human Immunodeficiency Virus and Hepatitis B Virus Leads to an Increase in Intracellular Hepatitis B Surface Antigen

David M Iser, Nadia Warner, Peter A Revill, Ajantha Solomon, Fiona Wightman, Suha Saleh, Megan Crane, Paul U Cameron, Scott Bowden, Tin Nguyen, Candida F Pereira, Paul V Desmond, Stephen A Locarnini, Sharon R Lewin

Journal article  |  2010  |  Journal of Virology

Leucocytoclastic and renal vasculitis in a patient with autoimmune pancreatitis: new associations

M Garg, S Mackay, PA Hill, J Katsoulis, S McLaughlin, PV Desmond, RYM Chen

Journal article  |  2010  |  Internal Medicine Journal

Hepatitis B surface antigen levels during the natural history of chronic hepatitis B: A perspective on Asia

Tin Nguyen, Alexander JV Thompson, Scott Bowden, Catherine Croagh, Sally Bell, Paul V Desmond, Miriam Levy, Stephen A Locarnini

Journal article  |  2010  |  Journal of Hepatology

HBV in the Poorly Compliant Patient: Dare we Start Oral Drugs?

T Nguyen, P Desmond, S Locarnini

Book Chapter  |  2010

Endoscopic ultrasound of pancreatic cystic lesions

undefined Prasad, undefined Wilson, undefined Kalade, PVD Desmond, undefined Chen

Journal article  |  2010  |  Inflammatory Bowel Diseases

The role of quantitative hepatitis B serology in the natural history and management of chronic hepatitis B

Tin Nguyen, Paul Desmond, Stephen Locarnini

Journal article  |  2009  |  Hepatology International

NO INCREASE IN INTRAHEPATIC MONONUCLEAR CELL OR STELLATE CELL ACTIVATION IN HIV-HBV CO-INFECTED INDIVIDUALS WITH ADVANCED HIV AND MILD LIVER DISEASE

David M Iser, Alison J Boyd, Anchalee Avihingsanon, Alex L Thompson, Tin Nguyen, Gail Matthews, Scott Bowden, Stephen Locarnini, John Slavin, Paul V Desmond, Gregory J Dore, Kiat Ruxrungtham, Sharon R Lewin

Conference Proceedings  |  2009  |  Hepatology

Single balloon enteroscopy versus double balloon enteroscopy, a randomised controlled trial

M Efthymiou, P Desmond, A Taylor

Conference Proceedings  |  2009  |  Journal of Gastroenterology and Hepatology

IDENTIFICATION OF NOVEL HEPATITIS B VIRUS (HBV) T-CELL EPITOPES AND ESCAPE MUTATIONS IN ASIAN INDIVIDUALS WITH CHRONIC HBV INFECTION USING A POPULATION BASED APPROACH

Christopher P Desmond, Silvana Gaudieri, Ian James, Katja Pfafferott, Abha Chopra, George K Lau, Stephen Locarnini, Peter A Revill, Caroline F Day, Sarah Chivers, Adam Gordon, Scott Bowden, Anna Ayres, Paul V Desmond, Alex J Thompson, Stuart K Roberts, Simon A Mallal, Sharon R Lewin

Conference Proceedings  |  2009  |  Hepatology

Prospective study in assessing effectiveness of cold biopsy polypectomy for treating diminutive polyps

M Efthymiou, A Taylor, P Desmond, RY Chen

Conference Proceedings  |  2009  |  Journal of Gastroenterology and Hepatology

Review of tips experience at a victorian tertiary hospital

N Ding, P De Cruz, L Lim, SJ Bell, PV Desmond

Conference Proceedings  |  2009  |  JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Acute food bolus impaction and eosinophilic oesophagitis

N Ding, M Efthymiou, S Bell, P Desmond

Conference Proceedings  |  2009  |  Journal of Gastroenterology and Hepatology

Characteristics of HBeAg-positive patients chronically infected with hepatitis B virus (HBV) who achieved hbsag loss/seroconversion following tenofovir disoproxil fumarate (TDF) treatment

W Sievert, EJ Gane, SI Strasser, J George, F Weilert, PA Desmond, EJ Heathcote, P Marcellin, J Sorbel, F Rousseau

Conference Proceedings  |  2009  |  Journal of Gastroenterology and Hepatology

Impact of High-Dose Peginterferon Alfa-2A on Virological Response Rates in Patients with Hepatitis C Genotype 1: a Randomized Controlled Trial

Stuart K Roberts, Martin D Weltman, Darrell HG Crawford, Geoffrey W McCaughan, William Sievert, Wendy S Cheng, William Rawlinson, Paul V Desmond, Phillipa S Marks, Motoko Yoshihara, Bishoy Rizkalla, Jean K DePamphilis, Gregory J Dore

Journal article  |  2009  |  Hepatology

Endoscopic ultrasound-guided fine needle aspiration for the diagnosis of sarcoidosis in two tertiary referral centres

LY Lim, BD Allen, P De Cruz, PB Allen, L Prideaux, SJ Bell, PV Desmond, RY Chen

Conference Proceedings  |  2009  |  Journal of Gastroenterology and Hepatology

Colonoscopy in the octogenarians and beyond

M Efthymiou, A Taylor, RY Chen, P Desmond

Conference Proceedings  |  2009  |  Journal of Gastroenterology and Hepatology

Adenoma detection rate in the national bowel cancer screening patients remains stable

M Efthymiou, A Taylor, R Chen, P Desmond

Conference Proceedings  |  2009  |  Journal of Gastroenterology and Hepatology

Impaired Quality of the Hepatitis B Virus (HBV)-Specific T-Cell Response in Human Immunodeficiency Virus Type 1-HBV Coinfection

J Judy Chang, Sunee Sirivichayakul, Anchalee Avihingsanon, Alex JV Thompson, Peter Revill, David Iser, John Slavin, Supranee Buranapraditkun, Pip Marks, Gail Matthews, David A Cooper, Stephen J Kent, Paul U Cameron, Joe Sasadeusz, Paul Desmond, Stephen Locarnini, Gregory J Dore, Kiat Ruxrungtham, Sharon R Lewin

Journal article  |  2009  |  Journal of Virology

Coordinate regulation of metabolic enzymes and transporters by nuclear transcription factors in human liver disease

Mario Congiu, Maurice L Mashford, John L Slavin, Paul V Desmond

Journal article  |  2009  |  Journal of Gastroenterology and Hepatology

Distribution of serotonin receptors and interacting proteins in the human sigmoid colon

N Chetty, IM Coupar, YY Tan, PV Desmond, HR Irving

Journal article  |  2009  |  Neurogastroenterology and Motility

Stimulation of the interleukin-1 receptor and Toll-like receptor 2 inhibits hepatitis B virus replication in hepatoma cell lines in vitro

Alex J Thompson, Danni Colledge, Sally Rodgers, Rachel Wilson, Peter Revill, Paul Desmond, Ashley Mansell, Kumar Visvanathan, Stephen Locarnini

Journal article  |  2009  |  Antiviral Therapy

Diagnosis of solid pancreatic masses by endoscopic ultrasound-guided fine-needle aspiration

JL Wilson, A Kalade, S Prasad, R Cade, B Thomson, S Banting, S Mackay, PV Desmond, RYM Chen

Journal article  |  2009  |  Internal Medicine Journal

Effect of the acute phase response induced by endotoxin administration on the expression and activity of UGT isoforms in rats.

Khalid M Alkharfy, Samuel M Poloyac, Mario Congiu, Paul V Desmond, Reginald F Frye

Journal article  |  2008  |  Drug Metabolism Letters

To evaluate the effect of endotoxin administration on the glucuronidation of multiple substrates in a rat model. In addition, the ..

Characterization of the innate immune signalling pathways in hepatocyte cell lines

S Preiss, A Thompson, X Chen, S Rodgers, V Markovska, P Desmond, K Visvanathan, K Li, S Locarnini, P Revill

Journal article  |  2008  |  Journal of Viral Hepatitis

Endoscopic ultrasound-guided fine-needle aspiration when combined with positron emission tomography improves specificity and overall diagnostic accuracy in unexplained mediastinal lymphadenopathy and staging of non-small-cell lung cancer

AV Kalade, WF Eddie Lau, M Conron, GM Wright, PV Desmond, RJ Hicks, R Chen

Journal article  |  2008  |  Internal Medicine Journal

Defective hepatitis B virus DNA is not associated with disease status but is reduced by polymerase mutations associated with drug resistance

Scott Preiss, Margaret Littlejohn, Peter Angus, Alex Thompson, Paul Desmond, Sharon R Lewin, Joe Sasadeusz, Gail Matthews, Gregory J Dore, Tim Shaw, Vitini Sozzi, Lilly Yuen, George Lau, Anna Ayres, Chloe Thio, Anchalee Avihingsanon, Kiat Ruxrungtham, Stephen Locarnini, Peter A Revill

Journal article  |  2008  |  Hepatology

Changing landscape of antiviral resistance management in chronic hepatitis B

Tin Nguyen, Stephen Locarnini, Paul Desmond

Journal article  |  2008  |  Journal of Gastroenterology and Hepatology

Glycosylation changes in hFUT1 transgenic mice increase TCR signaling and apoptosis resulting in thymocyte maturation arrest

Gregory TC Moore, Steven J Brown, Adam C Winterhalter, Mark Lust, Evelyn J Salvaris, Carly Selan, Harshal H Nandurkar, Paul V Desmond, Peter J Cowan, Anthony JF d'Apice

Journal article  |  2008  |  Molecular Immunology

Confocal endomicroscopy for in vivo detection of microvascular architecture in normal and malignant lesions of upper gastrointestinal tract

H Liu, YQ Li, T Yu, YA Zhao, JP Zhang, JN Zhang, YT Guo, XJ Xie, TG Zhang, PV Desmond

Journal article  |  2008  |  Journal of Gastroenterology and Hepatology

Plasma and gastric mucosal 5-hydroxytryptamine concentrations following cold water intake in patients with diarrhea-predominant irritable bowel syndrome

Xiu Li Zuo, Yan Qing Li, Xiao Zhong Yang, Min Guo, Yu Ting Guo, Xue Feng Lu, Jun Man Li, Paul V Desmond

Journal article  |  2007  |  Journal of Gastroenterology and Hepatology

The phenotype of hepatitis B virus-specific T cells differ in the liver and blood in chronic hepatitis B virus infection

J Judy Chang, Alexander JV Thompson, Kumar Visvanathan, Stephen J Kent, Paul U Cameron, Fiona Wightman, Paul Desmond, Stephen A Locarnini, Sharon R Lewin

Journal article  |  2007  |  Hepatology

Health professionals' attitudes toward caring for people with hepatitis C

JA Richmond, TL Dunning, PV Desmond

Journal article  |  2007  |  Journal of Viral Hepatitis

Erratum: 'Viral hepatitis: An A, B, C guide' (Medicine Today (2007))

C Croagh, P Desmond

Journal article  |  2007  |  Medicine Today

Viral hepatitis an A, B, C guide

C Croagh, P Desmond

Journal article  |  2007  |  Medicine Today

Lamivudine resistance in patients with chronic hepatitis B: Role of clinical and virological factors

Alexander JV Thompson, Anna Ayres, Lilly Yuen, Angeline Bartholomeusz, D Scott Bowden, David M Iser, Robert YM Chen, Barbara Demediuk, Gideon Shaw, Sally J Bell, Katrina JR Watson, Stephen A Locarnini, Paul V Desmond

Journal article  |  2007  |  Journal of Gastroenterology and Hepatology

Alterations of food antigen-specific serum immunoglobulins G and E antibodies in patients with irritable bowel syndrome and functional dyspepsia

XL Zuo, YQ Li, WJ Li, YT Guo, XF Lu, JM Li, PV Desmon

Journal article  |  2007  |  Clinical and Experimental Allergy

Comparison of 5-HT4 and 5-HT7 receptor expression and function in the circular muscle of the human colon

Helen R Irving, Yean Y Tan, Nathalie Tochon-Danguy, Haihuang Liu, Navinisha Chetty, Paul V Desmond, Colin W Pouton, Ian A Coupar

Journal article  |  2007  |  Life Sciences

Regulation of toll-like receptor-2 expression in chronic hepatitis B by the precore protein

Kumar Visvanathan, Narelle A Skinner, Alex JV Thompson, Stephen M Riordan, Vitini Sozzi, Roslyn Edwards, Sally Rodgers, Jelica Kurtovic, Judy Chang, Sharon Lewin, Paul Desmond, Stephen Locarnini

Journal article  |  2007  |  Hepatology

Agent Orange: Your new look JGH (the improvements go deeper than the cover)

GC Farrell, PV Desmond, BC Wong

Journal article  |  2007  |  Journal of Gastroenterology and Hepatology

Human 5-HT4 and 5-HT7 receptor splice vairants: Are they important?

Ian M Coupar, Paul V Desmond, Helen R Irving

Journal article  |  2007  |  Current Neuropharmacology

Alterations in cerebral potentials evoked by rectal distention and drinking ice water in patients with irritable bowel syndrome

Xiu Li Zuo, Yan Qing Li, Kun Ming Huang, Rong Guang Kuang, Guo Ping Lv, Xue Feng Lu, Jun Man Li, Paul V Desmond

Journal article  |  2006  |  Journal of Gastroenterology and Hepatology

Experience of endoscopic ultrasound in an Australian tertiary hospital

Andrius V Kalade, Paul V Desmond, Robert Y Chen

Journal article  |  2006  |  ANZ Journal of Surgery

Visceral hypersensitivity following cold water intake in subjects with irritable bowel syndrome

XL Zuo, YQ Li, L Shi, GP Lv, RG Kuang, XF Lu, JM Li, PV Desmond

Journal article  |  2006  |  Journal of Gastroenterology

The effect of erythromycin on video capsule endoscopy intestinal-transit time

GR Caddy, L Moran, AKH Chong, AM Miller, AC Taylor, PV Desmond

Journal article  |  2006  |  Gastrointestinal Endoscopy

Prospective study of the clinical impact of EUS

AKH Chong, GR Caddy, PV Desmond, RY Chen

Journal article  |  2005  |  Gastrointestinal Endoscopy

Associations between liver histology and severity of the metabolic syndrome in subjects with nonalcoholic fatty liver disease

MC Ryan, AM Wilson, J Slavin, JD Best, AJ Jenkins, PV Desmond

Journal article  |  2005  |  Diabetes Care

The accuracy of EUS-FNA in assessing mediastinal lymphadenopathy and staging patients with NSCLC

G Caddy, M Conron, G Wright, P Desmond, D Hart, RY Chen

Journal article  |  2005  |  European Respiratory Journal

Chronic hepatitis B: recommendations for therapy based on the natural history of disease in Australian patients

SJ Bell, A Lau, A Thompson, KJR Watson, B Demediuk, G Shaw, RY Chen, A Ayres, L Yuen, A Bartholomeusz, SA Locarnini, PV Desmond

Journal article  |  2005  |  Journal of Clinical Virology

Capsule endoscopy vs. push enteroscopy and enteroclysis in suspected small-bowel Crohn's disease

AKH Chong, A Taylor, A Miller, O Hennessy, W Connell, P Desmond

Journal article  |  2005  |  Gastrointestinal Endoscopy

The accuracy of endoscopic ultrasound fine needle aspiration in assessing mediastinal lymphadenopathy and staging patients with non-small cell lung carcinoma

GM Wright, G Caddy, M Conron, P Desmond, D Hart, R Chen

Journal article  |  2005  |  Eur Respir J

Altered immune system glycosylation causes colitis in alpha 1,2-fucosyltransferase transgenic mice

SJ Brown, AM Miller, PJ Cowan, J Slavin, WR Connell, GT Moore, S Bell, PR Elliott, PV Desmond, AJF d'Apice

Journal article  |  2004  |  Inflammatory Bowel Diseases

Practical difficulties in the management of hepatitis B in the Asia-Pacific region

R Mohamed, P Desmond, DJ Suh, D Amarapurkar, E Gane, Y Guangbi, JL Hou, W Jafri, CL Lai, CH Lee, SD Lee, SG Lim, R Guan, PH Phiet, T Piratvisuth, J Sollano, JC Wu

Journal article  |  2004  |  Journal of Gastroenterology and Hepatology

Hepatitis C: a medical and social diagnosis.

Jacqui Richmond, Patricia Dunning, Paul Desmond

Journal article  |  2004  |  Australian Nursing Journal

Hepatitis C has reached epidemic proportions in Australia. Because of its association with injecting drug use, which is a main tra..

Efficacy and safety of two-dose regimens of peginterferon alpha-2a compared with interferon alpha-2a in chronic hepatitis C: A multicenter, randomized controlled trial

PJ Pockros, R Carithers, P Desmond, D Dhumeaux, MW Fried, P Marcellin, ML Shiffman, G Minuk, KR Reddy, RW Reindollar, A Lin, MJ Brunda

Journal article  |  2004  |  American Journal of Gastroenterology

Visceral perception thresholds after rectal thermal and pressure stimuli in irritable bowel syndrome patients

Y Li, Y Wang, X Zuo, Y Guo, H Zhang, X Lu, J Li, PV Desmond

Journal article  |  2004  |  European Journal of Gastroenterology and Hepatology

Prospective assessment of the diagnostic and therapeutic impact of small-bowel push enteroscopy

ACF Taylor, RJ Buttigieg, IG McDonald, PV Desmond

Journal article  |  2003  |  Endoscopy

Initial experience with capsule endoscopy at a major referral hospital

AKH Chong, ACF Taylor, AM Miller, PV Desmond

Journal article  |  2003  |  Medical Journal of Australia

Effects of interferon alpha therapy on the catalytic domains of the polymerase gene and basal core promoter, precore and core regions of hepatitis B virus

RYM Chen, S Bowden, PV Desmond, J Dean, SA Locarnini

Journal article  |  2003  |  Journal of Gastroenterology and Hepatology

Distinctive patterns of gene expression in premalignant gastric mucosa and gastric cancer

A Boussioutas, H Li, J Liu, P Waring, S Lade, AJ Holloway, D Taupin, K Gorringe, I Haviv, PV Desmond, DDL Bowtell

Journal article  |  2003  |  Cancer Research

Effect of the G1896A precore mutation on drug sensitivity and replication yield of lamivudine-resistant HBV in vitro

RYM Chen, R Edwards, T Shaw, D Colledge, WE Delaney, H Isom, S Bowden, P Desmond, SA Locarnini

Journal article  |  2003  |  Hepatology

Emerging therapies of hepatitis B and C

RYM Chen, PV Desmond, SA Locarnini

Journal article  |  2002  |  Journal of Gastroenterology and Hepatology

Factors associated with severity of hepatic fibrosis in people with chronic hepatitis C infection

M Danta, GJ Dore, L Hennessy, YM Li, CR Vickers, H Harley, M Ngu, W Reed, PV Desmond, W Sievert, GC Farrell, JM Kaldor, RG Batey

Journal article  |  2002  |  Medical Journal of Australia

Hepatotoxicity of antimicrobial agents

SJ Brown, PV Desmond

Journal article  |  2002  |  Seminars in Liver Disease

Use of an overtube for enteroscopy: depth of insertion.

J Bures, S Rejchrt

Journal article  |  2002  |  Endoscopy

Push enteroscopy: A single centre experience and review of published series

RYM Chen, ACF Taylor, PV Desmond

Journal article  |  2002  |  ANZ Journal of Surgery

UDP glucuronosyltransferase mRNA levels in human liver disease

M Congiu, ML Mashford, JL Slavin, PV Desmond

Journal article  |  2002  |  Drug Metabolism & Disposition

Introduction of lamivudine for the treatment of chronic hepatitis B: Expected clinical and economic outcomes based on 4-year clinical trial data

S Crowley, D Tognarini, P Desmond, M Lees, G Saal

Journal article  |  2002  |  Journal of Gastroenterology and Hepatology

Prospective assessment of magnetic resonance cholangiopancreatography for noninvasive imaging of the biliary tree

ACF Taylor, AF Little, OF Hennessy, SW Banting, PJ Smith, PV Desmond

Journal article  |  2002  |  Gastrointestinal Endoscopy

How can we measure insertion depth during the enteroscopic push procedure?

S Mosca, F Morace, M Secondulfo

Journal article  |  2001  |  Endoscopy

Fas-mediated hepatocyte apoptosis is increased by hepatitis C virus infection and alcohol consumption, and may be associated with hepatic fibrosis: mechanisms of liver cell injury in chronic hepatitis C virus infection

S Pianko, S Patella, G Ostapowicz, P Desmond, W Sievert

Journal article  |  2001  |  Journal of Viral Hepatitis

Investigation of potential iatrogenic transmission of hepatitis C in Victoria, Australia

CC Trasancos, MA Kainer, PV Desmond, H Kelly

Journal article  |  2001  |  Australian and New Zealand Journal of Public Health

Liver toxicity. Could this be a drug reaction?

M Ryan, P Desmond

Journal article  |  2001  |  Australian Family Physician

BACKGROUND: Adverse reaction to prescription medications, over the counter medications and complementary medicines, are an importa..

Changes in hepatitis C-related liver disease in a large clinic population

G Ostapowicz, M Dallinger, SJ Bell, SI Strasser, KJR Watson, J Slavin, J Santamaria, PV Desmond

Journal article  |  2001  |  Internal Medicine Journal

Use of an overtube for enteroscopy - Does it increase depth of insertion? A prospective study of enteroscopy with and without an overtube

ACF Taylor, RYM Chen, PV Desmond

Journal article  |  2001  |  Endoscopy

Erratum: Prospective comparison of MRCP and ERCP, analysis of factors predicting diagnosis and preliminary cost-analysis of different approaches (HPB (2000) 2 (123))

ACF Taylor, AF Little, SW Banting, OF Hennessy, PJ Smith, PV Desmond

Journal article  |  2000  |  HPB

A randomized, placebo-controlled study to evaluate the efficacy of 12-month famciclovir treatment in patients with chronic hepatitis B e antigen-positive hepatitis B.

RA de Man, P Marcellin, F Habal, P Desmond, T Wright, T Rose, R Jurewicz, C Young

Journal article  |  2000  |  Hepatology

We conducted a randomized, placebo-controlled clinical study evaluating famciclovir (500 mg 3 times daily and 1.5 g once daily) fo..

Cost-effectiveness analysis of lamivudine for the treatment of chronic hepatitis B

SJ Crowley, D Tognarini, PV Desmond, M Lees

Journal article  |  2000  |  PharmacoEconomics

Bilirubin and bile acids may modulate their own metabolism via regulating uridine diphosphate-glucuronosyltransferase expression in the rat

YQ Li, DA Prentice, ML Howard, ML Mashford, PV Desmond

Journal article  |  2000  |  Journal of Gastroenterology and Hepatology

Where does treatment fit into the strategy to control hepatitis C?

P Desmond

Conference Proceedings  |  2000  |  Journal of Gastroenterology and Hepatology

Alcohol up-regulates UDP-glucuronosyltransferase mRNA expression in rat liver and in primary rat hepatocyte culture.

YQ Li, DA Prentice, ML Howard, ML Mashford, JS Wilson, PV Desmond

Journal article  |  2000  |  Life Sciences

The interactions between alcohol and cytochrome P-450 enzymes have been well investigated. However, the data regarding the effect ..

Severity of liver disease in hepatitis C infection contracted through injecting drug use.

G Ostapowicz, SJ Bell, PV Desmond

Journal article  |  1999  |  Australian and New Zealand Journal of Medicine

BACKGROUND: Injecting drug use (IDU) is currently the most common route of hepatitis C virus (HCV) transmission in Australia and m..

Imaging of the normal and abnormal pancreaticobiliary system with single-shot MR cholangiopancreatography: a pictorial review.

AF Little, PJ Smith, WK Lee, OF Hennessy, PV Desmond, SW Banting, ME Lourensz

Journal article  |  1999  |  Australasian Radiology

Magnetic resonance cholangiopancreatography (MRCP) is a rapidly evolving non-invasive imaging modality that produces images of the..

The effect of hormones on the expression of five isoforms of UDP-glucuronosyltransferase in primary cultures of rat hepatocytes.

YQ Li, DA Prentice, ML Howard, ML Mashford, PV Desmond

Journal article  |  1999  |  Pharmaceutical Research

PURPOSE: To investigate the direct effects of sex hormones, growth hormone, thyroid hormones and dexamethasone on the regulation o..

Role of alcohol in the progression of liver disease caused by hepatitis C virus infection.

G Ostapowicz, KJ Watson, SA Locarnini, PV Desmond

Journal article  |  1998  |  Hepatology

In patients with chronic hepatitis C, alcohol consumption has been proposed as a risk factor for the progression of liver disease;..

Regulation of uridine diphosphate glucuronosyltransferase during the acute-phase response

SI Strasser, ML Mashford, PV Desmond

Journal article  |  1998  |  Journal of Gastroenterology and Hepatology

What do I need to know about hepatitis C?

K Watson, I Anderson, P Coghlan, P Desmond, F Dudley, G Farrell, B Jones, G McCaughan, W Reed, J Rowe, J Scally

Journal article  |  1997  |  Modern Medicine of Australia

Sex hormones differentially regulate isoforms of UDP-glucuronosyltransferase.

SI Strasser, SA Smid, ML Mashford, PV Desmond

Journal article  |  1997  |  Pharmaceutical Research

PURPOSE: To investigate the role of sex hormones in the regulation of UDP-glucuronosyltransferase (UGT). METHODS: We examined live..

Sequential increases in the intrahepatic expression of epidermal growth factor, basic fibroblast growth factor, and transforming growth factor beta in a bile duct ligated rat model of cirrhosis.

J Napoli, D Prentice, C Niinami, GA Bishop, P Desmond, GW McCaughan

Journal article  |  1997  |  Hepatology

Chronic hepatic regeneration constitutes an important part of the cirrhotic process. The factors regulating chronic hepatic regene..

UDP-glucuronosyltransferase in the regenerating rat liver.

AM Pellizzer, SA Smid, SI Strasser, CS Lee, ML Mashford, PV Desmond

Journal article  |  1996  |  Journal of Gastroenterology and Hepatology

In both acute and chronic liver disease in man, elimination of drugs metabolized by the cytochrome P450 (CYP) enzymes is impaired...

Preventing endoscopic retrograde cholangiopancreatography related sepsis: a randomized controlled trial comparing two antibiotic regimes.

BC Smith, JR Alqamish, KJ Watson, RG Shaw, JH Andrew, PV Desmond

Journal article  |  1996  |  Journal of Gastroenterology and Hepatology

Current antibiotic prophylaxis for endoscopic retrograde cholangiopancreatography (ERCP) is not standardized and may be inadequate..

UDP-glucuronosyltransferase in Gilbert's syndrome.

HS Debinski, CS Lee, AP Dhillon, P Mackenzie, J Rhode, PV Desmond

Journal article  |  1996  |  Pathology

The diagnosis of Gilbert's syndrome, a condition characterised by mild jaundice related to chronic unconjugated hyperbilirubinemia..

UDP glucuronosyltransferase in the cirrhotic rat liver

HS Debinski, PI MacKenzie, CS Lee, ML Mashford, JA Danks, TR Tephly, M Green, PV Desmond

Journal article  |  1996  |  Journal of Gastroenterology and Hepatology

Current perspectives in hepatitis C.

BC Smith, SI Strasser, PV Desmond

Journal article  |  1995  |  Australian and New Zealand Journal of Medicine

RISK-FACTORS FOR THE DEVELOPMENT OF AMOXICILLIN-CLAVULANIC ACID ASSOCIATED JAUNDICE

JA THOMSON, CK FAIRLEY, AM UGONI, AB FORBES, PM PURCELL, PV DESMOND, RA SMALLWOOD, JJ MCNEIL

Journal article  |  1995  |  Medical Journal of Australia

Outpatient liver biopsy using ultrasound guidance and the Biopty gun is safe and cost effective.

BC Smith, PV Desmond

Journal article  |  1995  |  Australian and New Zealand Journal of Medicine

BACKGROUND: The need for liver biopsy is increasing with the increasing availability of treatments for liver disease, in particula..

Flucloxacillin hepatitis--an Australian epidemic.

PV Desmond

Journal article  |  1995  |  Australian and New Zealand Journal of Medicine

Evaluation of blood donors with equivocal hepatitis C serological results.

SI Strasser, BC Smith, KJ Watson, PJ Coghlan, SA Locarnini, PV Desmond

Journal article  |  1995  |  Medical Journal of Australia

OBJECTIVE: To characterise blood donors with equivocal hepatitis C serological results and to develop an algorithm for their diagn..

Localization of uridine 5'-diphosphate-glucuronosyltransferase in human liver injury.

HS Debinski, CS Lee, JA Danks, PI Mackenzie, PV Desmond

Journal article  |  1995  |  Gastroenterology

BACKGROUND/AIMS: Pharmacokinetic studies in patients with cirrhosis have shown a decreased clearance of drugs metabolized by cytoc..

Risk factors and predictors of outcome in an Australian cohort with hepatitis C virus infection.

SI Strasser, KJ Watson, CS Lee, PJ Coghlan, PV Desmond

Journal article  |  1995  |  Medical Journal of Australia

OBJECTIVES: To define demographic and epidemiological features of an Australian population with chronic hepatitis C virus (HCV) in..

Factors affecting the hepatic elimination of oxidized and of glucoronidated high clearance drugs following acute administration of carbon tetrachloride.

R Callaghan, P Paull, PV Desmond, ML Mashford

Journal article  |  1994  |  Journal of Hepatology

The factors affecting drug elimination following acute administration of carbon tetrachloride (CCl4) were investigated using a per..

Release of latent glucuronosyltransferase activity contributes to the sparing of glucuronidation in experimental liver injuries

PV DESMOND, FE SMYTH, ML MASHFORD

Journal article  |  1994  |  Journal of Gastroenterology and Hepatology

A Prospective study of septic complications of endoscopic retrograde cholangiopancreatography

LC MOLLISON, PV DESMOND, KA STOCKMAN, JH ANDREW, K WATSON, G SHAW, K BREEN

Journal article  |  1994  |  Journal of Gastroenterology and Hepatology

The effect of a nutritional model of chronic liver injury on the hepatic glucuronidation of morphine in rats.

R Callaghan, PV Desmond, ML Mashford

Journal article  |  1993  |  Journal of Pharmacy and Pharmacology

The effect of a choline-deficient diet on the hepatic glucuronidation of morphine was investigated using a rat perfused liver syst..

Acute hepatitis induced by ingestion of the herbal medication chaparral.

BC Smith, PV Desmond

Journal article  |  1993  |  Australian and New Zealand Journal of Medicine

Hepatic enzyme activity is the major factor determining elimination rate of high-clearance drugs in cirrhosis.

R Callaghan, PV Desmond, P Paull, ML Mashford

Journal article  |  1993  |  Hepatology

The relative importance of alterations in hepatic enzyme activity, blood flow and drug binding to drug elimination in patients wit..

Relapsing pancreatitis due to juxta-pancreatic duodenal duplication cyst with pancreatic ductal communication.

KY Ng, PV Desmond, N Collier

Journal article  |  1993  |  ANZ Journal of Surgery

A 21 year old patient first presented with acute pancreatitis in infancy, followed by subsequent episodes of relapsing pancreatiti..

RISK-FACTORS FOR DEVELOPMENT OF FLUCLOXACILLIN ASSOCIATED JAUNDICE

CK FAIRLEY, JJ MCNEIL, P DESMOND, R SMALLWOOD, H YOUNG, A FORBES, P PURCELL, I BOYD

Journal article  |  1993  |  BMJ

Extracorporeal shock wave lithotripsy combined with litholytic therapy in the treatment of patients with symptomatic gallstones--the Melbourne experience.

ID Vellar, PV Desmond, CP Pritchard, SW Banting, KL Salomon, D Vellar, MA Henderson

Journal article  |  1993  |  Medical Journal of Australia

OBJECTIVE: To investigate the role of extracorporeal shock wave lithotripsy using the Dornier MPL9000 lithotripter and adjuvant li..

Watermelon stomach: an unusual cause of chronic gastrointestinal blood loss.

MN Merrett, D Machet, J Ring, PV Desmond, CJ Martin

Journal article  |  1991  |  ANZ Journal of Surgery

Watermelon stomach, or gastric antral vascular ectasia, is an uncommon cause of gastrointestinal blood loss, which can easily be o..

Current options for the management of gallstones.

PV Desmond

Journal article  |  1991  |  Medical Journal of Australia

Approximately 20% of the Australian population will develop gallstones. On current evidence, patients with asymptomatic gallstones..

Achalasia of the oesophagus: treatments with pneumatic dilatation.

EJ Prewett, PV Desmond, KJ Breen

Journal article  |  1990  |  Journal of Gastroenterology and Hepatology

A series of 51 patients with achalasia of the oesophagus treated by pneumatic dilatation between 1980 and 1988 is reported. Treatm..

Extracorporeal shock wave lithotripsy for bile duct stones: an Australian experience.

MN Merrett, PV Desmond

Journal article  |  1990  |  Journal of Gastroenterology and Hepatology

Choledocholithiasis requires prompt therapy, particularly if complicated by ascending cholangitis. Endoscopic sphincterotomy with ..

Fatal air embolism following endoscopy of a hepatic portoenterostomy.

PV Desmond, RA MacMahon

Journal article  |  1990  |  Endoscopy

The case reported is that of a 10-year-old girl born with congenital biliary atresia who had undergone a Kasai procedure in the fi..

The effect of an antacid and food on the absorption of cimetidine and ranitidine.

PV Desmond, PJ Harman, N Gannoulis, M Kamm, ML Mashford

Journal article  |  1990  |  Journal of Pharmacy and Pharmacology

The effect of varying doses of a liquid antacid preparation containing magnesium hydroxide, aluminum hydroxide and simethicone on ..

Removal of impacted endoscopic basket and stone from the common bile duct by extracorporeal shock waves.

M Merrett, P Desmond

Journal article  |  1990  |  Endoscopy

Hepatic extraction of morphine is impaired in cirrhosis.

B Crotty, KJ Watson, PV Desmond, ML Mashford, LJ Wood, J Colman, FJ Dudley

Journal article  |  1989  |  European Journal of Clinical Pharmacology

Using hepatic vein catheterization this study has provided the first direct measurement of morphine hepatic extraction in 8 contro..

Pemphigus vulgaris of the esophagus.

MA Kamm, JA Brenan, DJ Davies, PV Desmond

Journal article  |  1988  |  Journal of Clinical Gastroenterology

We describe a case of pemphigus vulgaris involving the lower esophagus, in a patient with gastroesophageal reflux. As near as we c..

Studies on the mechanisms of action of activated charcoal on theophylline pharmacokinetics.

RS Mckinnon, PV Desmond, PJ Harman, M Kamm, H Ghabrial, CJ Martin, ML Mashford

Journal article  |  1987  |  Journal of Pharmacy and Pharmacology

Oral administration of repeated doses of activated charcoal to volunteers and dogs significantly increased the systemic clearance ..

Alcohol and drug interactions

PV DESMOND, B CROTTY

Journal article  |  1987  |  Journal of Gastroenterology and Hepatology

Metoclopramide--a review.

PV Desmond, KJ Watson

Journal article  |  1986  |  Medical Journal of Australia

Metoclopramide has wide applications in both clinical and experimental medicine. It is useful in the management of gastro-oesophag..

Hepatic vein occlusion (Budd-Chiari syndrome): problems in diagnosis and management.

KJ Breen, R Buttigieg, PV Desmond, G Whelan, KJ Watson, E Gilford

Journal article  |  1986  |  Australian and New Zealand Journal of Medicine

Seven patients demonstrating the difficulties in diagnosis and management of hepatic vein occlusion are presented. The syndrome ma..

THE EFFECTS OF AGE AND CHRONIC LIVER-DISEASE ON THE ELIMINATION OF TEMAZEPAM

H GHABRIAL, PV DESMOND, KJR WATSON, AJ GIJSBERS, PJ HARMAN, KJ BREEN, ML MASHFORD

Journal article  |  1986  |  European Journal of Clinical Pharmacology

The Zollinger-Ellison syndrome: a review of the St Vincent's Hospital, Melbourne experience.

D Vellar, M Henderson, ID Vellar, P Desmond

Journal article  |  1985  |  ANZ Journal of Surgery

Eight cases of the Zollinger-Ellison syndrome were diagnosed at St Vincent's Hospital in the period 1966-84. Although a rare tumou..

Drug therapy of anxiety disorders.

P Desmond, E Harari

Journal article  |  1985  |  Australian family physician

ULTRASOUND IN THE DIAGNOSIS OF JAUNDICE - A REVIEW

D COOPER, J TARRANT, G WHELAN, CB STYLES, M COOK, PV DESMOND

Journal article  |  1985  |  Medical Journal of Australia

Disposition of intravenous glycofurol: effect of hepatic cirrhosis.

RW Bury, KJ Breen, PV Desmond, K Raymond, ML Mashford

Journal article  |  1984  |  Clinical Pharmacology and Therapeutics

The disposition of intravenous glycofurol, a solvent for some drugs, was followed in nine male patients with hepatic cirrhosis. In..

Decreased oral warfarin clearance after ranitidine and cimetidine.

PV Desmond, ML Mashford, PJ Harman, BJ Morphett, KJ Breen, YM Wang

Journal article  |  1984  |  Clinical Pharmacology and Therapeutics

Oxidative metabolism inhibition of a number of drugs by cimetidine has been attributed to its imidazole ring, a hypothesis that ha..

A [14C]phenacetin breath test to measure hepatic function in man.

KJ Breen, RW Bury, IV Calder, PV Desmond, M Peters, ML Mashford

Journal article  |  1984  |  Hepatology

Phenacetin, a high-clearance drug, was labeled as [14C-ethyl]phenacetin and used in a breath test of hepatic function. 14CO2 appea..

Use of single doses and rapid sampling to detect interactions with cimetidine.

H Ghabrial, PJ Harman, PV Desmond, ML Mashford, KJ Breen

Journal article  |  1984  |  European Journal of Clinical Pharmacology

In this study the well-established interaction between cimetidine and theophylline has been demonstrated using only a single dose ..

Mephenytoin hydroxylation deficiency: kinetics after repeated doses.

A Küpfer, P Desmond, R Patwardhan, S Schenker, RA Branch

Journal article  |  1984  |  Clinical Pharmacology and Therapeutics

Deficient aromatic hydroxylation of S-mephenytoin was observed in an index subject during a kinetic study of stereoselective metab..

Treatment of reflux oesophagitis. A randomized, controlled evaluation of cimetidine.

KJ Breen, PV Desmond, G Whelan

Journal article  |  1983  |  Medical Journal of Australia

Twenty-five patients were studied in an eight-week randomized controlled comparison of cimetidine and placebo in the treatment of ..

Periportal localization of lorazepam glucuronidation in the isolated perfused rat liver.

RA Branch, R Cotham, R Johnson, J Porter, PV Desmond, S Schenker

Journal article  |  1983  |  The Journal of Laboratory and Clinical Medicine

The relative effects of pretreatment with allyl alcohol and carbon tetrachloride on oxidative and glucuronide metabolism of loraze..

Ranitidine does not affect chlormethiazole or indocyanine green disposition.

ML Mashford, PJ Harman, BJ Morphett, KJ Breen, PV Desmond

Journal article  |  1983  |  Clinical Pharmacology and Therapeutics

Cimetidine has been shown to inhibit hepatic mixed-function oxidase activity and to lower hepatic blood flow. It is not known whet..

The effect of ethanol administration on the disposition and elimination of chlormethiazole.

RW Bury, PV Desmond, ML Mashford, B Westwood, G Shaw, KJ Breen

Journal article  |  1983  |  European Journal of Clinical Pharmacology

Acutely administered ethanol has been shown to inhibit the hepatic metabolism of a number of drugs. Ethanol might be expected to d..

Stereoselective metabolism and disposition of the enantiomers of mephenytoin during chronic oral administration of the racemic drug in man.

A Küpfer, PV Desmond, S Schenker, RA Branch

Journal article  |  1982  |  Journal of Pharmacology and Experimental Therapeutics

Alcohol unrelated hepato-biliary disorders in the alcoholic: the role of liver biopsy in determining the aetiology of liver disease.

G Whelan, M Peters, PV Desmond, PS Bhathal

Journal article  |  1982  |  Australian and New Zealand Journal of Medicine

Alcoholics with abnormal liver function tests are generally assumed to have one of the recognised patterns of alcoholic liver inju..

Paracetamol self-poisoning: diagnosis, management, and outcome.

KJ Breen, RW Bury, PV Desmond, BH Forge, ML Mashford, G Whelan

Journal article  |  1982  |  Medical Journal of Australia

Over a four-year period, 103 patients presented to St Vincent's Hospital, Melbourne, after poisoning themselves with paracetamol. ..

Effect of ethanol on the disposition and elimination of chlormethiazole

P Desmond, K Breen, RW Bury

Journal article  |  1982  |  Clinical and Experimental Pharmacology and Physiology

Interaction between theophylline with a single dose of cimetidine

H Ghabrial, PV Desmond, PJ Harmen

Journal article  |  1982  |  Clinical and Experimental Pharmacology and Physiology

EFFECTS OF CIMETIDINE AND RANITIDINE ON HEPATIC DRUG-METABOLISM

KJ BREEN, R BURY, PV DESMOND, ML MASHFORD, B MORPHETT, B WESTWOOD, RG SHAW

Journal article  |  1982  |  Clinical Pharmacology and Therapeutics

Normal metabolism of morphine in cirrhosis.

RV Patwardhan, RF Johnson, A Hoyumpa, JJ Sheehan, PV Desmond, GR Wilkinson, RA Branch, S Schenker

Journal article  |  1981  |  Gastroenterology

Morphine disposition and elimination was studied in 6 healthy male subject s and 6 male patients with cirrhosis, to assess the rol..

Hepatic and extrahepatic glucuronidation of lorazepam in the dog.

JF Gerkens, PV Desmond, S Schenker, RA Branch

Journal article  |  1981  |  Hepatology

The pharmacokinetic disposition of lorazepam was investigated in sham-operated aneshetized dogs, dogs with hepatic devascularizati..

Acute viral hepatitis: diagnosis and management.

KJ Breen, PV Desmond

Journal article  |  1981  |  Australian Family Physician

Preservation of glucuronidation in carbon tetrachloride-induced acute liver injury in the rat.

PV Desmond, R James, S Schenker, JF Gerkens, RA Branch

Journal article  |  1981  |  Biochemical Pharmacology

The differential localization of various drug metabolizing systems within the rat liver lobule as determined by the hepatotoxins allyl alcohol, carbon tetrachloride and bromobenzene.

R James, P Desmond, A Küpfer, S Schenker, RA Branch

Journal article  |  1981  |  Journal of Pharmacology and Experimental Therapeutics

Rats were pretreated with allyl alcohol, carbon tetrachloride or bromobenzene to induce histopathological evidence of periportal, ..

Cimetidine impairs the elimination of chlormethiazole.

G Shaw, RW Bury, ML Mashford, KJ Breen, PV Desmond

Journal article  |  1981  |  European Journal of Clinical Pharmacology

Cimetidine impairs the systemic clearance of a number of low extraction drugs and this study examines its effect on the oral clear..

Cimetidine impairs the clearance of an orally administered high clearance drug, chlormethiazole

PV Desmond, RG Shaw, RW Bury

Journal article  |  1981  |  Gastroenterology

Effect of short-term ethanol administration on lorazepam clearance.

AM Hoyumpa, R Patwardhan, M Maples, PV Desmond, RF Johnson, AP Sinclair, S Schenker

Journal article  |  1981  |  Hepatology

The disposition of chlordiazepoxide (Librium) and diazepam (Valium), compounds which are initially degraded by oxidative processes..

Cardiac arrest after intravenous injection of cimetidine.

RG Shaw, ML Mashford, PV Desmond

Journal article  |  1980  |  Medical Journal of Australia

Three episodes, in which patients suffered a cardiac arrest in close association with receiving a bolus intravenous injection of c..

Cimetidine spares the glucuronidation of lorazepam and oxazepam.

RV Patwardhan, GW Yarborough, PV Desmond, RF Johnson, S Schenker, KV Speeg

Journal article  |  1980  |  Gastroenterology

Lorazepam (Ativan) disposition and elimination were studied in 8 normal subjects before and after 1 wk of cimetidine therapy, 300 ..

Short-term ethanol administration impairs the elimination of chlordiazepoxide (Librium) in man.

PV Desmond, RV Patwardhan, S Schenker, AM Hoyumpa

Journal article  |  1980  |  European Journal of Clinical Pharmacology

Ethanol may enhance the sedative effect of benzodiazepines leading to greater psychomotor impairment, but the mechanism is not cle..

Effects of caffeine on plasma free fatty acids, urinary catecholamines, and drug binding.

RV Patwardhan, PV Desmond, RF Johnson, GD Dunn, DH Robertson, AM Hoyumpa, S Schenker

Journal article  |  1980  |  Clinical Pharmacology and Therapeutics

The effects of caffeine (250 mg orally) on plasma free fatty acids (FFA), urinary catecholamines, and drug binding were studied in..

Cimetidine impairs elimination of chlordiazepoxide (Librium) in man.

PV Desmond, RV Patwardhan, S Schenker, KV Speeg

Journal article  |  1980  |  Annals of Internal Medicine

We have studied chlordiazepoxide (Librium) disposition and elimination in eight normal subjects before and after 1 week of cimetid..

Comparison of [14C] phenacetin and amino[14C]pyrine breath tests after acute and chronic liver injury in the rat.

PV Desmond, RA Branch, I Calder, S Schenker

Journal article  |  1980  |  Experimental Biology and Medicine

Cryptic nature of bromocriptine therapy in portal systemic encephalopathy.

S Schenker, PV Desmond, KV Speeg, AM Hoyumpa

Journal article  |  1980  |  Gastroenterology

Effect of cimetidine and other antihistaminics on the elimination of aminopyrine, phenacetin and caffeine.

PV Desmond, R Patwardhan, R Parker, S Schenker, KV Speeg

Journal article  |  1980  |  Life Sciences

Impaired elimination of caffeine by oral contraceptive steroids.

RV Patwardhan, PV Desmond, RF Johnson, S Schenker

Journal article  |  1980  |  The Journal of Laboratory and Clinical Medicine

The effect of OCS on the disposition and elimination of caffeine was examined. Caffeine (250 mg) was administered orally to 13 hea..

Impaired elimination of caffeine in cirrhosis.

PV Desmond, RV Patwardhan, RF Johnson, S Schenker

Journal article  |  1980  |  Digestive Diseases and Sciences

The effect of cirrhosis on the disposition and elimination of caffeine was examined. Caffeine (250 mg) was administered orally to ..

Effect of ethanol on benzodiazepine disposition in dogs.

AM Hoyumpa, PV Desmond, RK Roberts, S Nichols, RF Johnson, S Schenker

Journal article  |  1980  |  The Journal of Laboratory and Clinical Medicine

Effect of heparin administration on plasma binding of benzodiazepines.

PV Desmond, RK Roberts, AJ Wood, GD Dunn, GR Wilkinson, S Schenker

Journal article  |  1980  |  British Journal of Clinical Pharmacology

1 The effect of intravenous administration of 100 units of heparin on plasma of diazepam, chlordiazepoxide, oxazepam and lorazepam..

Differential effect of cimetidine on hepatic drug elimination

RV Patwardhan, G Yarborough, PV Desmond

Journal article  |  1980  |  Gastroenterology

Plasma binding of benzodiazepines in humans.

RF Johnson, S Schenker, RK Roberts, PV Desmond, GR Wilkinson

Journal article  |  1979  |  Journal of Pharmaceutical Sciences

Plasma binding of chlordiazepoxide, diazepam, loraxepam, and oxazepam was determined by equilibrium dialysis in 20 male, healthy v..

Chlordiazepoxide in acute alcoholism.

PV Desmond, S Schenker

Journal article  |  1979  |  British Journal of Clinical Pharmacology

Disposition of chlordiazepoxide: sex differences and effects of oral contraceptives.

RK Roberts, PV Desmond, GR Wilkinson, S Schenker

Journal article  |  1979  |  Clinical Pharmacology & Therapeutics

There is considerable interspecies and interdrug variability in the effect of sex differences and oral contraceptive (OC) steroids..

Drug prescribing in hepatobiliary disease.

RK Roberts, PV Desmond, S Schenker

Journal article  |  1979  |  Drugs