Hok Yuen

Toxoplasma gondii, Herpesviridae and long-term risk of transition to first-episode psychosis in an ultra high-risk sample.

E Burkhardt, M Berger, RH Yolken, A Lin, HP Yuen, SJ Wood, SM Francey, A Thompson, PD McGorry, B Nelson, AR Yung, GP Amminger

Journal article  |  2021  |  Schizophr Res

BACKGROUND: Ultra high-risk (UHR) criteria were introduced to identify people at imminent risk of developing psychosis. To improve..

Cannabidiol for at risk for psychosis youth: A randomized controlled trial

G Paul Amminger, Ashleigh Lin, Melissa Kerr, Amber Weller, Jessica Spark, Charlotte Pugh, Sally O'Callaghan, Maximus Berger, Scott R Clark, James G Scott, Andrea Baker, Iain McGregor, David Cotter, Zoltan Sarnyai, Andrew Thompson, Alison R Yung, Brian O'Donoghue, Eoin Killackey, Cathy Mihalopoulos, Hok Pan Yuen, et al.

Journal article  |  2021  |  EARLY INTERVENTION IN PSYCHIATRY

BACKGROUND: No biological treatment has been firmly established for the at-risk stage of psychotic disorder. In this study we aim ..

Functional Connectivity in Antipsychotic-Treated and Antipsychotic-Naive Patients With First-Episode Psychosis and Low Risk of Self-harm or Aggression A Secondary Analysis of a Randomized Clinical Trial

Sidhant Chopra, Shona M Francey, Brian O'Donoghue, Kristina Sabaroedin, Aurina Arnatkeviciute, Vanessa Cropley, Barnaby Nelson, Jessica Graham, Lara Baldwin, Steven Tahtalian, Hok Pan Yuen, Kelly Allott, Mario Alvarez-Jimenez, Susy Harrigan, Christos Pantelis, Stephen J Wood, Patrick McGorry, Alex Fornito

Journal article  |  2021  |  JAMA PSYCHIATRY

Importance: Altered functional connectivity (FC) is a common finding in resting-state functional magnetic resonance imaging (rs-fM..

Cognitive ability and metabolic physical health in first-episode psychosis

Sarah Whitson, Brian O'Donoghue, Robert Hester, Lara Baldwin, Susy Harrigan, Shona Francey, Jessica Graham, Barnaby Nelson, Aswin Ratheesh, Mario Alvarez-Jimenez, Alex Fornito, Christos Pantelis, Hok Pan Yuen, Andrew Thompson, Melissa Kerr, Michael Berk, Stephen J Wood, Patrick McGorry, Kelly Allott

Journal article  |  2021  |  SCHIZOPHRENIA RESEARCH-COGNITION

Cognitive impairments are a core feature of first-episode psychosis (FEP), arising before illness onset and antipsychotic exposure..

Preventive interventions for individuals at ultra high risk for psychosis: An updated and extended meta-analysis

Cristina Mei, Mark van der Gaag, Barnaby Nelson, Filip Smit, Hok Pan Yuen, Maximus Berger, Marija Krcmar, Paul French, G Paul Amminger, Andreas Bechdolf, Pim Cuijpers, Alison R Yung, Patrick D McGorry

Journal article  |  2021  |  CLINICAL PSYCHOLOGY REVIEW

Intervention at the earliest illness stage, in ultra or clinical high-risk individuals, or indicated prevention, currently represe..

Effective Connectivity of Fronto-Striato-Thalamic Circuitry Across the Psychosis Continuum

Kristina Sabaroedin, Adeel Razi, Sidhant Chopra, Nancy Tran, Andrii Pozaruk, Zhaolin Chen, Amy Finlay, Barnaby Nelson, Kelly Allott, Mario Alvarez-Jimenez, Jessica Graham, Lara Baldwin, Steven Tahtalian, Hok P Yuen, Susy Harrigan, Vanessa Cropley, Sujit Sharma, Bharat Saluja, Robert Williams, Christos Pantelis, et al.

Journal article  |  2021  |  BIOLOGICAL PSYCHIATRY

Longitudinal Changes in Functional Connectivity in Antipsychotic-Treated and Antipsychotic-Naive Patients With First Episode Psychosis: A Randomized, Triple-Blind Placebo-Controlled fMRI Study

Sidhant Chopra, Shona Francey, Brian O'Donoghue, Kristina Sabaroedin, Aurina Arnatkeviciute, Vanessa Cropley, Barnaby Nelson, Jessica Graham, Lara Baldwin, Hok Pan Yuen, Kelly Allott, Mario Alvarez-Jimenez, Susy Harrigan, Christos Pantelis, Stephen Wood, Patrick McGorry, Alex Fornito

Journal article  |  2021  |  BIOLOGICAL PSYCHIATRY

Differentiating the effect of antipsychotic medication and illness on brain volume reductions in first-episode psychosis: A Longitudinal, Randomised, Triple-blind, Placebo-controlled MRI Study

Sidhant Chopra, Alex Fornito, Shona M Francey, Brian O'Donoghue, Vanessa Cropley, Barnaby Nelson, Jessica Graham, Lara Baldwin, Steven Tahtalian, Hok Pan Yuen, Kelly Allott, Mario Alvarez-Jimenez, Susy Harrigan, Kristina Sabaroedin, Christos Pantelis, Stephen J Wood, Patrick McGorry

Journal article  |  2021  |  NEUROPSYCHOPHARMACOLOGY

Changes in brain volume are a common finding in Magnetic Resonance Imaging (MRI) studies of people with psychosis and numerous lon..

Greater preference for eveningness is associated with negative symptoms in an ultra-high risk for psychosis sample

Jashmina J Shetty, Christian Nicholas, Barnaby Nelson, Patrick D McGorry, Suzie Lavoie, Connie Markulev, Miriam R Schafer, Andrew Thompson, Hok Pan Yuen, Alison R Yung, Dorien H Nieman, Lieuwe de Haan, G Paul Amminger, Jessica A Hartmann

Journal article  |  2021  |  EARLY INTERVENTION IN PSYCHIATRY

AIM: Investigating biological processes in at-risk individuals may help elucidate the aetiological mechanisms underlying psychosis..

Pluripotential Risk and Clinical Staging: Theoretical Considerations and Preliminary Data From a Transdiagnostic Risk Identification Approach

Jessica A Hartmann, Patrick D McGorry, Louise Destree, G Paul Amminger, Andrew M Chanen, Christopher G Davey, Rachid Ghieh, Andrea Polari, Aswin Ratheesh, Hok Pan Yuen, Barnaby Nelson

Journal article  |  2021  |  FRONTIERS IN PSYCHIATRY

Most psychiatric disorders develop during adolescence and young adulthood and are preceded by a phase during which attenuated or e..