Graeme Clark

Creating the Bionic Ear The Central Role of Cybernetics

Graeme Clark

Journal article  |  2017  |  IEEE Technology and Society Magazine

SDHA related tumorigenesis: a new case series and literature review for variant interpretation and pathogenicity

Ruth T Casey, David B Ascher, Eleanor Rattenberry, Louise Izatt, Katrina A Andrews, Helen L Simpson, Benjamen Challis, Soo-Mi Park, Venkata R Bulusu, Fiona Lalloo, Douglas EV Pires, Hannah West, Graeme R Clark, Philip S Smith, James Whitworth, Thomas G Papathomas, Phillipe Taniere, Rosina Savisaar, Laurence D Hurst, Emma R Woodward, et al.

Journal article  |  2017  |  Molecular Genetics & Genomic Medicine

Effective area and charge density of dextran sulphate doped PEDOT modified electrodes

Alexander R Harris, Paul J Molino, Robert MI Kapsa, Graeme M Clark, Antonio G Paolini, Gordon G Wallace

Journal article  |  2016  |  Synthetic Metals

An X-ray fluorescence microscopic analysis of the tissue surrounding the multi-channel cochlear implant electrode array.

Kathryn Spiers, Tina Cardamone, John B Furness, Jonathan CM Clark, James F Patrick, Graeme M Clark

Journal article  |  2016  |  Cochlear Implants International

OBJECTIVES: The aim of this study was to analyse the tissue surrounding the University of Melbourne's (UOMs) multi-channel cochlea..

Thin-film micro-electrode stimulation of the cochlea in rats exposed to aminoglycoside induced hearing loss

BJ Allitt, AR Harris, SJ Morgan, GM Clark, AG Paolini

Journal article  |  2016  |  Hearing Research

Correlation of Impedance and Effective Electrode Area of Dextran Sulfate Doped PEDOT Modified Electrodes

Alexander R Harris, Robyn Hutchinson, Paul J Molino, Robert MI Kapsa, Graeme M Clark, Antonio G Paolini, Gordon G Wallace

Journal article  |  2016  |  Journal of The Electrochemical Society

The multi-channel cochlear implant: Multi-disciplinary development of electrical stimulation of the cochlea and the resulting clinical benefit

Graeme M Clark

Journal article  |  2015  |  Hearing Research

Optical and Electrochemical Methods for Determining the Effective Area and Charge Density of Conducting Polymer Modified Electrodes for Neural Stimulation

Alexander R Harris, Paul J Molino, Robert MI Kapsa, Graeme M Clark, Antonio G Paolini, Gordon G Wallace

Journal article  |  2015  |  Analytical Chemistry

Correlation of the impedance and effective electrode area of doped PEDOT modified electrodes for brain-machine interfaces

Alexander R Harris, Paul J Molino, Robert MI Kapsa, Graeme M Clark, Antonio G Paolini, Gordon G Wallace

Journal article  |  2015  |  The Analyst

Biomedical studies on temporal bones of the first multi-channel cochlear implant patient at the University of Melbourne.

Graeme M Clark, Jonathan Clark, Tina Cardamone, Maria Clarke, Prue Nielsen, Rob Jones, Benedicta Arhatari, Nick Birbilis, Roger Curtain, Jin Xu, Sheryl Wagstaff, Peter Gibson, Stephen O'Leary, John Furness

Journal article  |  2014  |  Cochlear Implants International

OBJECTIVE: To analyse the temporal bones and implant of the first University of Melbourne's (UOM) patient (MC-1) to receive the mu..

The multichannel cochlear implant for severe-to-profound hearing loss.

Graeme M Clark

Journal article  |  2013  |  Nature Medicine

The Evolving Science of Cochlear Implants

Graeme M Clark, Jonathan CM Clark, John B Furness

Journal article  |  2013  |  JAMA: Journal of the American Medical Association

Engineering a multimodal nerve conduit for repair of injured peripheral nerve

AF Quigley, KJ Bulluss, ILB Kyratzis, K Gilmore, T Mysore, KSU Schirmer, EL Kennedy, M O'Shea, YB Truong, SL Edwards, G Peeters, P Herwig, JM Razal, TE Campbell, KN Lowes, MJ Higgins, SE Moulton, MA Murphy, MJ Cook, GM Clark, et al.

Journal article  |  2013  |  Journal of Neural Engineering

In vitro growth and differentiation of primary myoblasts on thiophene based conducting polymers

Anita F Quigley, Klaudia Wagner, Magdalena Kita, Kerry J Gilmore, Michael J Higgins, Robert D Breukers, Simon E Moulton, Graeme M Clark, Anthony J Penington, Gordon G Wallace, David L Officer, Robert MI Kapsa

Journal article  |  2013  |  Biomaterials Science

Midbrain responses to micro-stimulation of the cochlea using high density thin-film arrays

BJ Allitt, SJ Morgan, S Bell, DAX Nayagam, B Arhatari, GM Clark, AG Paolini

Journal article  |  2012  |  Hearing Research

The multi-channel cochlear implant and the relief of severe-to-profound deafness.

Graeme Clark

Journal article  |  2012  |  Cochlear Implants International

This personal reflection outlines the discoveries at the University of Melbourne leading to the multi-channel cochlear implant, an..

Inhibition of smooth muscle cell adhesion and proliferation on heparin-doped polypyrrole

EM Stewart, X Liu, GM Clark, RMI Kapsa, GG Wallace

Journal article  |  2012  |  Acta Biomaterialia

Biocompatibility of Immobilized Aligned Carbon Nanotubes

David AX Nayagam, Richard A Williams, Jun Chen, Kylie A Magee, Jennifer Irwin, Justin Tan, Peter Innis, Ronald T Leung, Sue Finch, Chris E Williams, Graeme M Clark, Gordon G Wallace

Journal article  |  2011  |  Small

The multi-channel cochlear implant: Psychoacoustics and speech perception

G Clark

Conference Proceedings  |  2010  |  Int. Congr. Acoustics, ICA - Incorporating Proc. Annu. Conf. Aust. Acoustical Soc.

Pneumococcal meningitis post-cochlear implantation: potential routes of infection and pathophysiology.

Benjamin PC Wei, Robert K Shepherd, Roy M Robins-Browne, Graeme M Clark, Stephen J O'Leary

Journal article  |  2010  |  Otolaryngology-Head and Neck Surgery

OBJECTIVE: This review describes the current concept of pneumococcal meningitis in cochlear implant recipients based on recent lab..

Pneumococcal meningitis post-cochlear implantation: preventative measures.

Benjamin PC Wei, Robert K Shepherd, Roy M Robins-Browne, Graeme M Clark, Stephen J O'Leary

Journal article  |  2010  |  Otolaryngology-Head and Neck Surgery

OBJECTIVE: Both clinical data and laboratory studies demonstrated the risk of pneumococcal meningitis post-cochlear implantation. ..

Creating conductive structures for cell growth: Growth and alignment of myogenic cell types on polythiophenes

RD Breukers, KJ Gilmore, M Kita, KK Wagner, MJ Higgins, SE Moulton, GM Clark, DL Officer, RMI Kapsa, GG Wallace

Journal article  |  2010  |  JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Conducting polymers, dual neurotrophins and pulsed electrical stimulation - Dramatic effects on neurite outgrowth

Brianna C Thompson, Rachael T Richardson, Simon E Moulton, Alison J Evans, Stephen O'Leary, Graeme M Clark, Gordon G Wallace

Journal article  |  2010  |  Journal of Controlled Release

A Conducting-Polymer Platform with Biodegradable Fibers for Stimulation and Guidance of Axonal Growth

Anita F Quigley, Joselito M Razal, Brianna C Thompson, Simon E Moulton, Magdalena Kita, Elizabeth L Kennedy, Graeme M Clark, Gordon G Wallace, Robert MI Kapsa

Journal article  |  2009  |  ADVANCED MATERIALS

Wet-Spun Biodegradable Fibers on Conducting Platforms: Novel Architectures for Muscle Regeneration

Joselito M Razal, Magdalena Kita, Anita F Quigley, Elizabeth Kennedy, Simon E Moulton, Robert MI Kapsa, Graeme M Clark, Gordon G Wallace

Journal article  |  2009  |  ADVANCED FUNCTIONAL MATERIALS

Skeletal muscle cell proliferation and differentiation on polypyrrole substrates doped with extracellular matrix components

Kerry J Gilmore, Magdalena Kita, Yao Han, Amy Gelmi, Michael J Higgins, Simon E Moulton, Graeme M Clark, Robert Kapsa, Gordon G Wallace

Journal article  |  2009  |  BIOMATERIALS

Promoting neurite outgrowth from spiral ganglion neuron explants using polypyrrole/BDNF-coated electrodes

Alison J Evans, Brianna C Thompson, Gordon G Wallace, Rodney Millard, Stephen J O'Leary, Graeme M Clark, Robert K Shepherd, Rachael T Richardson

Journal article  |  2009  |  Journal of Biomedical Materials Research Part A

Polypyrrole-coated electrodes for the delivery of charge and neurotrophins to cochlear neurons

Rachael T Richardson, Andrew K Wise, Brianna C Thompson, Brianna O Flynn, Patrick J Atkinson, Nicole J Fretwell, James B Fallon, Gordon G Wallace, Rob K Shepherd, Graeme M Clark, Stephen J O'Leary

Journal article  |  2009  |  Biomaterials

Electrode-Cellular Interface

GG Wallace, SE Moulton, GM Clark

Journal article  |  2009  |  SCIENCE

The multi-channel cochlear implant: past, present and future perspectives.

Graeme Clark

Journal article  |  2009  |  Cochlear Implants Int.

Initial research demonstrated that only low frequencies could be mimicked with rate of electrical stimulation, and thus multi-chan..

Personal reflections on the multichannel cochlear implant and a view of the future

Graeme M Clark

Journal article  |  2008  |  Journal of Rehabilitation Research and Development

Can we prevent cochlear implant recipients from developing pneumococcal meningitis?

Benjamin PC Wei, Roy M Robins-Browne, Robert K Shepherd, Graeme M Clark, Stephen J O'Leary

Journal article  |  2008  |  Clinical Infectious Diseases

The restoration of hearing to persons with severely or profoundly impaired hearing by means of a cochlear implant is one of the gr..

Meningitis after cochlear implantation

Benjamin PC Wei, Graeme M Clark, Stephen J O'Leary, Robert K Shepherd, Roy M Robins-Browne

Journal article  |  2007  |  British Medical Journal

Assessment of the protective effect of pneumococcal vaccination in preventing meningitis after cochlear implantation

Benjamin PC Wei, Roy M Robins-Browne, Robert K Shepherd, Kristy Azzopardi, Graeme M clark, Stephen J O'Leary

Journal article  |  2007  |  Archives of Otolaryngology - Head & Neck Surgery

Effects of inner ear trauma on the risk of pneumococcal meningitis

Benjamin PC Wei, Robert K Shepherd, Roy M Robins-Browne, Graeme M Clark, Stephen J O'Leary

Journal article  |  2007  |  Archives of Otolaryngology - Head & Neck Surgery

The effect of polypyrrole with incorporated neurotrophin-3 on the promotion of neurite outgrowth from auditory neurons

Rachael T Richardson, Brianna Thompson, Simon Moulton, Carrie Newbold, May Ghee Lum, Adrian Cameron, Gordon Wallace, Robert Kapsa, Graeme Clark, Stephen O'Leary

Journal article  |  2007  |  Biomaterials

3D finite element analyses of insertion of the Nucleus standard straight and the Contour electrode arrays into the human cochlea

HN Kha, BK Chen, GM Clark

Journal article  |  2007  |  Journal of Biomechanics

Pneumococcal meningitis threshold model: A potential tool to assess infectious risk of new or existing inner ear surgical interventions

Benjamin PC Wei, Robert K Shepherd, Roy M Robins-Browne, Graeme M Clark, Stephen J O'Leary

Journal article  |  2006  |  Otology & Neurotology- An International Forum

Optimising the incorporation and release of a neurotrophic factor using conducting polypyrrole

Brianna C Thompson, Simon E Moulton, Jie Ding, Rachael Richardson, Adrian Cameron, Stephen O'Leary, Gordon G Wallace, Graeme M Clark

Journal article  |  2006  |  Journal of Controlled Release

Pneumococcal meningitis: Development of a new animal model

Benjamin PC Wei, Robert K Shepherd, Roy A Robins-Browne, Graeme M Clark, Stephen J O'Leary

Journal article  |  2006  |  Otology & Neurotology- An International Forum

The multiple-channel cochlear implant: the interface between sound and the central nervous system for hearing, speech, and language in deaf people - a personal perspective

Graeme M Clark

Journal article  |  2006  |  Royal Society of London. Proceedings B. Biological Sciences

Implant design and development

D GRAYDEN, G CLARK

Book Chapter  |  2006

Resprouting and survival of guinea pig cochlear neurons in response to the administration of the neurotrophins brain-derived neurotrophic factor and neurotrophin-3

AK Wise, R Richardson, J Hardman, G Clark, S O'Leary

Journal article  |  2005  |  Journal of Comparative Neurology

A single dose of neurotrophin-3 to the cochlea surrounds spiral ganglion neurons and provides trophic support

RT Richardson, S O'Leary, A Wise, J Hardman, G Clark

Journal article  |  2005  |  Hearing Research

Delivery of neurotrophin-3 to the cochlea using alginate beads

F Noushi, RT Richardson, T Hardman, G Clark, S O'Leary

Journal article  |  2005  |  Otology & Neurotology- An International Forum

Balanced inhibition and excitation underlies spike firing regularity in ventral cochlear nucleus chopper neurons

AG Paolini, JC Clarey, K Needham, GM Clark

Journal article  |  2005  |  European Journal of Neuroscience

Stiffness properties for Nucleus standard straight and contour electrode arrays

HN Kha, BK Chen, GM Clark, R Jones

Journal article  |  2004  |  Medical Engineering and Physics

Fast inhibition alters first spike timing in auditory brainstem neurons

AG Paolini, JC Clarey, K Needham, GM Clark

Journal article  |  2004  |  Journal of Neurophysiology

Optimizing dynamic range in children using the nucleus cochlear implant

PW Dawson, JA Decker, CE Psarros

Journal article  |  2004  |  Ear and Hearing

Delayed neurotrophin treatment supports auditory neuron survival in deaf guinea pigs

LN Gillespie, GM Clark, PL Marzella

Journal article  |  2004  |  NeuroReport

Ventral cochlear nucleus coding of voice onset time in naturally spoken syllables

JC Clarey, AG Paolini, DB Grayden, AN Burkitt, GM Clark

Journal article  |  2004  |  Hearing Research

Cochlear implants in children: safety as well as speech and language

G Clark

Journal article  |  2003  |  International Journal of Pediatric Otorhinolaryngology

BDNF-induced survival of auditory neurons in vivo: Cessation of treatment leads to accelerated loss of survival effects

LN Gillespie, GM Clark, PF Bartlett, PL Marzella

Journal article  |  2003  |  Journal of Neuroscience Research

Evaluation of trajectories and contact pressures for the straight nucleus cochlear implant electrode array - a two-dimensional application of finite element analysis

BK Chen, GM Clark, R Jones

Journal article  |  2003  |  Medical Engineering and Physics

Cochlear implants: fundamentals and applications

GM CLARK

Book  |  2003

Rate-of-processing ability in children using cochlear implants and its relevance to speech perception.

PW Dawson, CM McKay, PA Busby, GM Clark

Journal article  |  2002  |  Cochlear Implants International

The aim was to assess the ability of young children using cochlear implants to process a change in place of stimulation under cond..

Short-term auditory memory in children using cochlear implants and its relevance to receptive language

PW Dawson, PA Busby, CM McKay, GM Clark

Journal article  |  2002  |  Journal of Speech Language and Hearing Research

Cognitive processing in children using cochlear implants: The relationship between visual memory, attention, and executive functions and developing language skills

VN Surowiecki, J Sarant, P Maruff, PJ Blamey, PA Busby, GM Clark

Journal article  |  2002  |  Annals of Otology, Rhinology and Laryngology

Speech perception outcomes in older children who use multichannel cochlear implants: Older is not always poorer

RC Dowell, SJ Dettman, K Hill, E Winton, EJ Barker, GM Clark

Journal article  |  2002  |  Annals of Otology, Rhinology and Laryngology

Speech perception in children using cochlear implants: prediction of long-term outcomes.

Richard C Dowell, Shani J Dettman, Peter J Blamey, Elizabeth J Barker, Graeme M Clark

Journal article  |  2002  |  Cochlear Implants International

A group of 102 children using the Nucleus multichannel cochlear implant were assessed for open-set speech perception abilities at ..

Chronic monopolar high rate stimulation of the auditory nerve - Physiological and histopathological effects

M Tykocinski, N Linahan, RK Shepherd, GM Clark

Book Chapter  |  2002

Learning to understand speech with the cochlear implant

GM CLARK

Book Chapter  |  2002

Summation of spatiotemporal input patterns in leaky integrate-and-fire neurons: Application to neurons in the cochlear nucleus receiving converging auditory nerve fiber input

L Kuhlmann, AN Burkitt, A Paolini, GM Clark

Journal article  |  2002  |  Journal of Computational Neuroscience

History of the cochlear implant

GM CLARK

Book Chapter  |  2002

A comparison of a new prototype Tickle Talker™ with the Tactaid 7

KL Galvin, J Ginis, RC Cowan, PJ Blamey, GM Clark

Journal article  |  2001  |  Australian and New Zealand Journal of Audiology

Synchronization of the neural response to noisy periodic synaptic input

AN Burkitt, GM Clark

Journal article  |  2001  |  Neural Computation

The role of radiographic phase-contrast imaging in the development of intracochlear electrode arrays

J Xu, AW Stevenson, DC Gao, M Tykocinski, D Lawrence, SW Wilkins, GM Clark, E Saunders, RS Cowan

Journal article  |  2001  |  Otology & Neurotology- An International Forum

Temporal processing from the auditory nerve to the medial nucleus of the trapezoid body in the rat

AG Paolini, JV FitzGerald, AN Burkitt, GM Clark

Journal article  |  2001  |  Hearing Research

Delay analysis in the auditory brainstem of the rat: comparison with click latency

JV FitzGerald, AN Burkitt, GM Clark, AG Paolini

Journal article  |  2001  |  Hearing Research

Surgical implications of perimodiolar cochlear implant electrode design: avoiding intracochlear damage and scala vestibuli insertion.

RJ Briggs, M Tykocinski, E Saunders, W Hellier, M Dahm, B Pyman, GM Clark

Journal article  |  2001  |  Cochlear Implants International

OBJECTIVE: To review the mechanisms and nature of intracochlear damage associated with cochlear implant electrode array insertion,..

Psychophysics of a prototype peri-modiolar cochlear implant electrode array

LT Cohen, E Saunders, GM Clark

Journal article  |  2001  |  Hearing Research

LIF is more potent than BDNF In promoting neurite outgrowth of mammalian auditory neurons in vitro

LN Gillespie, GM Clark, PF Bartlett, PL Marzella

Journal article  |  2001  |  NeuroReport

Variation in speech perception scores among children with cochlear implants

JZ Sarant, PJ Blamey, RC Dowell, GM Clark, WPR Gibson

Journal article  |  2001  |  Ear and Hearing

Peak-Splitting in the Response of the Leaky Integrate-and-Fire Neuron Model to Low-Frequency Periodic Inputs

L KUHLMANN, AN BURKITT, GM CLARK

Conference Proceedings  |  2001  |  Proceedings of the IEEE Engineering in Medicine and Biology Society Conference

Advances in Computational Modeling of Cochlear Implant Physiology and Perception

IC BRUCE, MW WHITE, LS IRLICHT, SJ O'LEARY, GM CLARK

Book Chapter  |  2001

The Contour electrode array: Safety study and initial patient trials of a new perimodiolar design

M Tykocinski, E Saunders, LT Cohen, C Treaba, RJS Briggs, P Gibson, GM Clark, RSC Cowan

Journal article  |  2001  |  Otology & Neurotology- An International Forum