Sally Beard

Aurora kinase mRNA expression is reduced with increasing gestational age and in severe early onset fetal growth restriction

Sally Beard, Natasha Pritchard, Natalie Binder, Karen Schindler, Natasha De Alwis, Tu'uhevaha J Kaitu'u-Lino, Stephen Tong, Natalie J Hannan

Journal article  |  2020  |  Placenta

INTRODUCTION: Oxidative damage and biochemical ageing are implicated in placental dysfunction and potentially fetal death. Cellula..

Circulating mRNAs are differentially expressed in pregnancies with severe placental insufficiency and at high risk of stillbirth

Natalie J Hannan, Owen Stock, Rebecca Spencer, Clare Whitehead, Anna L David, Katie Groom, Scott Petersen, Amanda Henry, Joanne M Said, Sean Seeho, Stefan C Kane, Lavinia Gordon, Sally Beard, Kantaraja Chindera, Smita Karegodar, Richard Hiscock, Natasha Pritchard, Tu'uhevaha J Kaitu'u-Lino, Susan P Walker, Stephen Tong

Journal article  |  2020  |  BMC Medicine

BACKGROUND: Fetuses affected by placental insufficiency do not receive adequate nutrients and oxygenation, become growth restricte..

The New Generation Antiplatelet Agent Prasugrel Represents an Exciting Novel Candidate Therapy for Preeclampsia.

Natasha De Alwis, Natalie Binder, Sally Beard, Nguyen Vi, Kaitu'u-Lino Tu'uhevaha, Stephen Tong, Natalie Hannan

Conference Proceedings  |  2020  |  REPRODUCTIVE SCIENCES

Proton Pump Inhibitors and Preeclampsia Risk Among 157 720 Women A Swedish Population Register-Based Cohort Study

Roxanne Hastie, Lina Bergman, Catherin A Cluver, Anna Wikman, Natalie J Hannan, Susan P Walker, Anna-Karin Wikstrom, Stephen Tong, Susanne Hesselman

Journal article  |  2019  |  Hypertension

Comparing the Ability of Pravastatin, Simvastatin and Rosuvastatin to Quench Markers of Endothelial Dysfunction in Pregnancy.

Natasha de Alwis, Sally Beard, Natalie Binder, Tu'uhevaha Kaitu'u-Lino, Fiona Brownfoot, Stephen Tong, Natalie Hannan

Conference Proceedings  |  2019  |  REPRODUCTIVE SCIENCES

New Generation Antiplatelet Agents Mitigate Pathophysiological Aspects of Preeclampsia in Both Human and Mouse Models of Preeclampsia, Representing Exciting Novel Candidate Therapeutics.

Natalie Hannan, Sally Beard, Natalie Binder, Natasha De Alwis, Natasha Pritchard, Tu'uhevaha Kaitu'u-Lino, Stephen Tong

Conference Proceedings  |  2019  |  REPRODUCTIVE SCIENCES

EGFL7 gene expression is regulated by hypoxia in trophoblast and altered in the plasma of patients with early preeclampsia

Clare L Whitehead, Tu'uhevaha J Kaitu'u-Lino, Natalie K Binder, Sally Beard, Natasha De Alwis, Fiona Brownfoot, Stephen Tong, Natalie J Hannan

Journal article  |  2018  |  Pregnancy Hypertension

Esomeprazole to treat women with preterm preeclampsia: a randomized placebo controlled trial

Catherine A Cluver, Natalie J Hannan, Erika van Papendorp, Richard Hiscock, Sally Beard, Ben W Mol, Gerhard B Theron, David R Hall, Eric H Decloedt, Marietjie Stander, Kim T Adams, Megan Rensburg, Pawel Schubert, Susan P Walker, Stephen Tong

Journal article  |  2018  |  American Journal of Obstetrics and Gynecology

AURORA KINASE EXPRESSION IS NOT ALTERED IN GROWTH RESTRICTED OR PREECLAMPTIC PLACENTAS, AND IS NOT CHANGED WITH PLACENTAL AGING

Natasha Pritchard, Sally Beard, Natalie Binder, Tu'uhevaha Kaitu'u-Lino, Stephen Tong, Natalie Hannan

Conference Proceedings  |  2018  |  PLACENTA

WATER-SOLUBLE EXTRACT OF CINNAMOMUM CASSIA AND ZINGIBER OFFICINALE INCREASE PLACENTAL GROWTH FACTOR AND DECREASE SFLT-1 SECRETED FROM ENDOTHELIAL AND PLACENTAL CELLS

Kenji Onda, Sally Beard, Rhotaro Shiota, Masaru Sakamaki, Stephen Tong, Toshihiko Hirano, Natalie J Hannan

Conference Proceedings  |  2018  |  PLACENTA

NOVEL STRATEGIES TO TREAT PREECLAMPSIA: FROM NEW DRUGS TO NEW DELIVERY

Natalie Hannan, Sally Beard, Natalie Binder, Tu'uhevaha Kaitu'u-Lino, Stephen Tong

Conference Proceedings  |  2018  |  PLACENTA

Melatonin enhances antioxidant molecules in the placenta, reduces secretion of soluble fms-like tyrosine kinase 1 (sFLT) from primary trophoblast but does not rescue endothelial dysfunction: An evaluation of its potential to treat preeclampsia

Natalie J Hannan, Natalie K Binder, Sally Beard, Nguyen Tuong-Vi, Tu'uhevaha J Kaitu'u-Lino, Stephen Tong

Journal article  |  2018  |  PLOS ONE

Combining metformin and esomeprazole is additive in reducing sFlt-1 secretion and decreasing endothelial dysfunction - implications for treating preeclampsia

Tu'uhevaha J Kaitu'u-Lino, Fiona C Brownfoot, Sally Beard, Ping Cannon, Roxanne Hastie, Tuong V Nguyen, Natalie K Binder, Stephen Tong, Natalie J Hannan

Journal article  |  2018  |  PLOS ONE

Measuring fetal brain and lung transcripts in amniotic fluid supernatant: a comparison of digital PCR and RT-qPCR methods

Lisa Hui, Sally Beard, Natalie J Hannan

Journal article  |  2018  |  The Journal of Maternal-Fetal & Neonatal Medicine

sFlt-1 and soluble endoglin concentrations in serum vs plasma in preterm preeclampsia: Are they interchangeable for biomarker studies?

Fiona Brownfoot, Tu'uhevaha Kaitu'u-Lino, Sally Beard, Stephen Tong, Natalie Hannan

Journal article  |  2017  |  Pregnancy Hypertension

Resveratrol inhibits release of soluble fms-like tyrosine kinase (sFlt-1) and soluble endoglin and improves vascular dysfunction - implications as a preeclampsia treatment

Natalie J Hannan, Fiona C Brownfoot, Ping Cannon, Minh Deo, Sally Beard, Tuong V Nguyen, Kirsten R Palmer, Stephen Tong, Tu'uhevaha J Kaitu'u-Lino

Journal article  |  2017  |  Scientific Reports

Relaxin treatment reduces angiotensin II-induced vasoconstriction in pregnancy and protects against endothelial dysfunction

Sarah A Marshall, Chen Huei Leo, Jane E Girling, Marianne Tare, Sally Beard, Natalie J Hannan, Laura J Parry

Journal article  |  2017  |  Biology of Reproduction

Key players of the necroptosis pathway RIPK1 and SIRT2 are altered in placenta from preeclampsia and fetal growth restriction

Natalie J Hannan, Sally Beard, Natalie K Binder, Kenji Onda, Tu'uhevaha J Kaitu'u-Lino, Qi Chen, Laura Tuohey, Manarangi De Silva, Stephen Tong

Journal article  |  2017  |  Placenta

Proton Pump Inhibitors Decrease Soluble fms-Like Tyrosine Kinase-1 and Soluble Endoglin Secretion, Decrease Hypertension, and Rescue Endothelial Dysfunction

Kenji Onda, Stephen Tong, Sally Beard, Natalie Binder, Masanaga Muto, Sevvandi N Senadheera, Laura Parry, Mark Dilworth, Lewis Renshall, Fiona Brownfoot, Roxanne Hastie, Laura Tuohey, Kirsten Palmer, Toshihiko Hirano, Masahito Ikawa, Tu'uhevaha Kaitu'u-Lino, Natalie J Hannan

Journal article  |  2017  |  Hypertension

Heme Oxygenase-1 Is Not Decreased in Preeclamptic Placenta and Does Not Negatively Regulate Placental Soluble fms-Like Tyrosine Kinase-1 or Soluble Endoglin Secretion

Stephen Tong, Tu'uhevaha J Kaitu'u-Lino, Kenji Onda, Sally Beard, Roxanne Hastie, Natalie K Binder, Cathy Cluver, Laura Tuohey, Clare Whitehead, Fiona Brownfoot, Manarangi De Silva, Natalie J Hannan

Journal article  |  2015  |  HYPERTENSION

Paternal obesity in a rodent model affects placental gene expression in a sex-specific manner

Natalie K Binder, Sally A Beard, Tu'uhevaha J Kaitu'u-Lino, Stephen Tong, Natalie J Hannan, David K Gardner

Journal article  |  2015  |  REPRODUCTION

Sofalcone Upregulates the Nuclear Factor (Erythroid-Derived 2)-Like 2/Heme Oxygenase-1 Pathway, Reduces Soluble fms-Like Tyrosine Kinase-1, and Quenches Endothelial Dysfunction Potential Therapeutic for Preeclampsia

Kenji Onda, Stephen Tong, Anzu Nakahara, Mei Kondo, Hideaki Monchusho, Toshihiko Hirano, Tu'uhevaha Kaitu'u-Lino, Sally Beard, Natalie Binder, Laura Tuohey, Fiona Brownfoot, Natalie J Hannan

Journal article  |  2015  |  HYPERTENSION

Characterization of protocols for primary trophoblast purification, optimized for functional investigation of sFlt-1 and soluble endoglin

Tu'uhevaha J Kaitu'u-Lino, Stephen Tong, Sally Beard, Roxanne Hastie, Laura Tuohey, Fiona Brownfoot, Kenji Onda, Natalie J Hannan

Journal article  |  2014  |  Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health

Cell-Type-Specific Transcriptional Profiles of the Dimorphic Pathogen Penicillium marneffei Reflect Distinct Reproductive, Morphological, and Environmental Demands

Shivani Pasricha, Michael Payne, David Canovas, Luke Pase, Nathamon Ngaosuwankul, Sally Beard, Alicia Oshlack, Gordon K Smyth, Sansanee C Chaiyaroj, Kylie J Boyce, Alex Andrianopoulos

Journal article  |  2013  |  G3: Genes, Genomes, Genetics

Tools for high efficiency genetic manipulation of the human pathogen Penicillium marneffei

Hayley E Bugeja, Kylie J Boyce, Harshini Weerasinghe, Sally Beard, Anne Jeziorowski, Shivani Pasricha, Michael Payne, Lena Schreider, Alex Andrianopoulos

Journal article  |  2012  |  Fungal Genetics and Biology