Srujana Sahebjada

A multi-ethnic genome-wide association study implicates collagen matrix integrity and cell differentiation pathways in keratoconus

Alison J Hardcastle, Petra Liskova, Yelena Bykhovskaya, Bennet J McComish, Alice E Davidson, Chris F Inglehearn, Xiaohui Li, Helene Choquet, Mahmoud Habeeb, Sionne EM Lucas, Srujana Sahebjada, Nikolas Pontikos, Karla E Rojas Lopez, Anthony P Khawaja, Manir Ali, Lubica Dudakova, Pavlina Skalicka, Bart TH Van Dooren, Annette JM Geerards, Christoph W Haudum, et al.

Journal article  |  2021  |  Communications Biology

Keratoconus is characterised by reduced rigidity of the cornea with distortion and focal thinning that causes blurred vision, howe..

Risk factors and association with severity of keratoconus: the Australian study of Keratoconus.

Srujana Sahebjada, Elsie Chan, Jing Xie, Grant R Snibson, Mark Daniell, Paul N Baird

Journal article  |  2021  |  International Ophthalmology

SIGNIFICANCE: Our results show that asthmatic patients tend to have more severe KC and thus close monitoring for disease progressi..

Eye rubbing in the aetiology of keratoconus: a systematic review and meta-analysis

Srujana Sahebjada, Haitham H Al-Mahrouqi, Sophia Moshegov, Sathiya M Panchatcharam, Elsie Chan, Mark Daniell, Paul N Baird

Journal article  |  2021  |  Graefe's Archive for Clinical and Experimental Ophthalmology

PURPOSE: Keratoconus is a potentially blinding condition that slowly deforms the cornea in young people. Despite the increasing pr..

Evaluating the Performance of Various Machine Learning Algorithms to Detect Subclinical Keratoconus

Ke Cao, Karin Verspoor, Srujana Sahebjada, Paul N Baird

Journal article  |  2020  |  Translational Vision Science and Technology

Purpose: Keratoconus (KC) represents one of the leading causes of corneal transplantation worldwide. Detecting subclinical KC woul..

Genome-wide association meta-analysis of corneal curvature identifies novel loci and shared genetic influences across axial length and refractive error

Qiao Fan, Alfred Pozarickij, Nicholas YQ Tan, Xiaobo Guo, Virginie JM Verhoeven, Veronique Vitart, Jeremy A Guggenheim, Masahiro Miyake, J Willem L Tideman, Anthony P Khawaja, Liang Zhang, Stuart MacGregor, Rene Hoehn, Peng Chen, Ginevra Biino, Juho Wedenoja, Seyed Ehsan Saffari, Milly S Tedja, Jing Xie, Carla Lanca, et al.

Journal article  |  2020  |  Communications Biology

Corneal curvature, a highly heritable trait, is a key clinical endophenotype for myopia - a major cause of visual impairment and b..

Factors affecting keratoconus progression and corneal collagen cross-linking

Elsie Chan, Harry Yip, Sara Vogrin, Srujana Sahebjada

Journal article  |  2020  |  Clinical and Experimental Ophthalmology

Association of Genetic Variation With Keratoconus

Bennet J McComish, Srujana Sahebjada, Yelena Bykhovskaya, Colin E Willoughby, Andrea J Richardson, Abi Tenen, Jac C Charlesworth, Stuart MacGregor, Paul Mitchell, Sionne EM Lucas, Richard A Mills, David A Mackey, Xiaohui Li, Jie Jin Wang, Richard A Jensen, Jerome I Rotter, Kent D Taylor, Alex W Hewitt, Yaron S Rabinowitz, Paul N Baird, et al.

Journal article  |  2020  |  JAMA Ophthalmology

Importance: Keratoconus is a condition in which the cornea progressively thins and protrudes in a conical shape, severely affectin..

Economic impact of keratoconus using a health expenditure questionnaire: A patient perspective

Elsie Chan, Paul N Baird, Sara Vogrin, Vijaya Sundararajan, Mark D Daniell, Srujana Sahebjada

Journal article  |  2020  |  Clinical and Experimental Ophthalmology

IMPORTANCE: This is the first study to estimate the lifetime costs associated with keratoconus based on a questionnaire completed ..

Do age-related macular degeneration genes show association with keratoconus?

Ke Cao, Srujana Sahebjada, Andrea J Richardson, Paul N Baird

Journal article  |  2019  |  Eye and Vision

Assessment of clinical parameters by ethnicity in patients with keratoconus: a multi-country study

Srujana Sahebjada, Elsie Chan, Myra McGuinness, Christopher Hodge, Calvin CP Pang, Govindasamy Kumaramanickavel, Gerard Sutton, Mark Daniell, Paul N Baird

Conference Proceedings  |  2019  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE