Belinda Parker

Colorimetric histology using plasmonically active microscope slides.

Eugeniu Balaur, Sandra O' Toole, Alex J Spurling, G Bruce Mann, Belinda Yeo, Kate Harvey, Catherine Sadatnajafi, Eric Hanssen, Jacqueline Orian, Keith A Nugent, Belinda S Parker, Brian Abbey

Journal article  |  2021  |  Nature

The human eye can distinguish as many as 10,000 different colours but is far less sensitive to variations in intensity1, meaning t..

A switch in mechanism of action attenuates doxorubicin-mediated cardiotoxicity.

Alison Cheong, Sean McGrath, Tina Robinson, Ruqaya Maliki, Alex Spurling, Ada Rephaeli, Abraham Nudelman, Don R Phillips, Belinda S Parker, Salvatore Pepe, Suzanne M Cutts

Conference Proceedings  |  2021  |  CANCER RESEARCH

Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis

Monisha Samuel, Pamali Fonseka, Rahul Sanwlani, Lahiru Gangoda, Sing Ho Chee, Shivakumar Keerthikumar, Alex Spurling, Sai V Chitti, Damien Zanker, Ching-Seng Ang, Ishara Atukorala, Taeyoung Kang, Sanjay Shahi, Akbar L Marzan, Christina Nedeva, Claire Vennin, Morghan C Lucas, Lesley Cheng, David Herrmann, Mohashin Pathan, et al.

Journal article  |  2021  |  NATURE COMMUNICATIONS

The concept that extracellular vesicles (EVs) from the diet can be absorbed by the intestinal tract of the consuming organism, be ..

Tumor microenvironmental cytokines bound to cancer exosomes determine uptake by cytokine receptor-expressing cells and biodistribution

Luize G Lima, Sunyoung Ham, Hyunku Shin, Edna PZ Chai, Erica SH Lek, Richard J Lobb, Alexandra F Muller, Suresh Mathivanan, Belinda Yeo, Yeonho Choi, Belinda S Parker, Andreas Moller

Journal article  |  2021  |  NATURE COMMUNICATIONS

Metastatic spread of a cancer to secondary sites is a coordinated, non-random process. Cancer cell-secreted vesicles, especially e..

High-content siRNA 3D co-cultures to identify myoepithelial cell-derived breast cancer suppressor proteins

Hendrika M Duivenvoorden, Natasha K Brockwell, Cameron J Nowell, Kaylene J Simpson, Belinda S Parker

Journal article  |  2021  |  SCIENTIFIC DATA

Understanding how cancer cells interact with the surrounding microenvironment early in breast cancer development can provide insig..

A switch in mechanism of action prevents doxorubicin-mediated cardiac damage

Alison Cheong, Sean McGrath, Tina Robinson, Ruqaya Maliki, Alex Spurling, Peter Lock, Ada Rephaeli, Abraham Nudelman, Belinda S Parker, Salvatore Pepe, Suzanne M Cutts

Journal article  |  2021  |  BIOCHEMICAL PHARMACOLOGY

Cancer patients treated with doxorubicin are at risk of congestive heart failure due to doxorubicin-mediated cardiotoxicity via to..

Plasmon-induced enhancement of ptychographic phase microscopy via sub-surface nanoaperture arrays

Eugeniu Balaur, Guido A Cadenazzi, Nicholas Anthony, Alex Spurling, Eric Hanssen, Jacqueline Orian, Keith A Nugent, Belinda S Parker, Brian Abbey

Journal article  |  2021  |  NATURE PHOTONICS

The invention of phase contrast microscopy revolutionized optics, enabling the visualization of highly optically transparent sampl..

Loss of type I IFN responsiveness impairs natural killer cell antitumor activity in breast cancer

Damien J Zanker, Katie L Owen, Nikola Baschuk, Alex J Spurling, Belinda S Parker

Journal article  |  2021  |  CANCER IMMUNOLOGY IMMUNOTHERAPY

Competent type I IFN signaling is the lynchpin of most immune surveillance mechanisms and has recently proven critical to the effi..

Prostate cancer cell-intrinsic interferon signaling regulates dormancy and metastatic outgrowth in bone

Katie L Owen, Linden J Gearing, Damien J Zanker, Natasha K Brockwell, Weng Hua Khoo, Daniel L Roden, Marek Cmero, Stefano Mangiola, Matthew K Hong, Alex J Spurling, Michelle McDonald, Chia-Ling Chan, Anupama Pasam, Ruth J Lyons, Hendrika M Duivenvoorden, Andrew Ryan, Lisa M Butler, John M Mariadason, Tri Giang Phan, Vanessa M Hayes, et al.

Journal article  |  2020  |  EMBO REPORTS

The latency associated with bone metastasis emergence in castrate-resistant prostate cancer is attributed to dormancy, a state in ..

Preliminary study highlights the potential of immune checkpoint inhibitors in sarcomatoid mesothelioma

Natasha K Brockwell, Muhammad Alamgeer, Beena Kumar, Gareth Rivalland, Thomas John, Belinda S Parker

Journal article  |  2020  |  TRANSLATIONAL LUNG CANCER RESEARCH

Background: Malignant pleural mesothelioma (MPM) is well known as an aggressive disease with poor survival. This has sparked trial..