James Camakaris

Copper comes of age in Melbourne

Julian FB Mercer, James Camakaris

Journal article  |  2016  |  METALLOMICS

When we were asked to produce articles for this volume, it seemed appropriate to us to co-author an article on the history and imp..

A commonly used Drosophila model of Alzheimer's disease generates an aberrant species of amyloid-beta with an additional N-terminal glutamine residue

Kirsten Allan, Keyla A Perez, Kevin J Barnham, James Camakaris, Richard Burke

Journal article  |  2014  |  FEBS LETTERS

Expression of human amyloid-β (Aβ) in Drosophila is frequently used to investigate its toxicity in vivo. We expressed Aβ1-42 in th..

Phosphorylation of Amyloid Precursor Protein at Threonine 668 Is Essential for Its Copper-responsive Trafficking in SH-SY5Y Neuroblastoma Cells

Karla M Acevedo, Carlos M Opazo, David Norrish, Leesa M Challis, Qiao-Xin Li, Anthony R White, Ashley I Bush, James Camakaris

Journal article  |  2014  |  JOURNAL OF BIOLOGICAL CHEMISTRY

Amyloid precursor protein (APP) undergoes post-translational modification, including O- and N-glycosylation, ubiquitination, and p..

Neuroprotective Copper Bis(thiosemicarbazonato) Complexes Promote Neurite Elongation

Laura Bica, Jeffrey R Liddell, Paul S Donnelly, Clare Duncan, Aphrodite Caragounis, Irene Volitakis, Brett M Paterson, Roberto Cappai, Alexandra Grubman, James Camakaris, Peter J Crouch, Anthony R White

Journal article  |  2014  |  PLOS ONE

Abnormal biometal homeostasis is a central feature of many neurodegenerative disorders including Alzheimer's disease (AD), Parkins..

Erratum: Copper modulates the large dense core vesicle secretory pathway in PC12 cells (Metallomics (2013) 5 (700-714) DOI:10.1039/C3MT20231C)

C Duncan, L Bica, PJ Crouch, A Caragounis, GE Lidgerwood, SJ Parker, J Meyerowitz, I Volitakis, JR Liddell, R Raghupathi, BM Paterson, MD Duffield, R Cappai, PS Donnelly, A Grubman, J Camakaris, DJ Keating, AR White

Journal article  |  2013  |  Metallomics

Presenilin Promotes Dietary Copper Uptake

Adam Southon, Mark A Greenough, George Ganio, Ashley I Bush, Richard Burke, James Camakaris

Journal article  |  2013  |  PLOS ONE

Dietary copper is essential for multicellular organisms. Copper is redox active and required as a cofactor for enzymes such as the..

Metal dyshomeostasis and oxidative stress in Alzheimer's disease

Mark A Greenough, James Camakaris, Ashley I Bush

Journal article  |  2013  |  NEUROCHEMISTRY INTERNATIONAL

Alzheimer's disease is the leading cause of dementia in the elderly and is defined by two pathological hallmarks; the accumulation..

Copper modulates the large dense core vesicle secretory pathway in PC12 cells

Clare Duncan, Laura Bica, Peter J Crouch, Aphrodite Caragounis, Grace E Lidgerwood, Sarah J Parker, Jodi Meyerowitz, Irene Volitakis, Jeffrey R Liddell, Ravinarayan Raghupathi, Brett M Paterson, Michael D Duffield, Roberto Cappai, Paul S Donnelly, Alexandra Grubman, James Camakaris, Damien J Keating, Anthony R White

Journal article  |  2013  |  METALLOMICS

Copper (Cu) is an essential biometal involved in a number of cell functions. Abnormal Cu homeostasis has been identified as a majo..

Copper modulates the large dense core vesicle secretory pathway in PC12 cells (vol 5, pg 700, 2013)

Clare Duncan, Laura Bica, Peter J Crouch, Aphrodite Caragounis, Grace E Lidgerwood, Sarah J Parker, Jodi Meyerowitz, Irene Volitakis, Jeffrey R Liddell, Ravinarayan Raghupathi, Brett M Paterson, Michael D Duffield, Roberto Cappai, Paul S Donnelly, Alexandra Grubman, James Camakaris, Damien J Keating, Anthony R White

Journal article  |  2013  |  METALLOMICS

Copper Transporting P-Type ATPases in the Brain

Sharon La Fontaine, James Camakaris, Julian Mercer

Book Chapter  |  2013

Mammals have two transmembrane copper transporting ATPases, which show a high degree of homology and play crucial roles in copper ..