James Camakaris

A commonly used Drosophila model of Alzheimer's disease generates an aberrant species of amyloid-beta with an additional N-terminal glutamine residue

Kirsten Allan, Keyla A Perez, Kevin J Barnham, James Camakaris, Richard Burke

Journal article  |  2014  |  FEBS Letters

Phosphorylation of Amyloid Precursor Protein at Threonine 668 Is Essential for Its Copper-responsive Trafficking in SH-SY5Y Neuroblastoma Cells

Karla M Acevedo, Carlos M Opazo, David Norrish, Leesa M Challis, Qiao-Xin Li, Anthony R White, Ashley I Bush, James Camakaris

Journal article  |  2014  |  JOURNAL OF BIOLOGICAL CHEMISTRY

Neuroprotective Copper Bis(thiosemicarbazonato) Complexes Promote Neurite Elongation

Laura Bica, Jeffrey R Liddell, Paul S Donnelly, Clare Duncan, Aphrodite Caragounis, Irene Volitakis, Brett M Paterson, Roberto Cappai, Alexandra Grubman, James Camakaris, Peter J Crouch, Anthony R White

Journal article  |  2014  |  PLOS ONE

Presenilin Promotes Dietary Copper Uptake

Adam Southon, Mark A Greenough, George Ganio, Ashley I Bush, Richard Burke, James Camakaris

Journal article  |  2013  |  PLOS ONE

Metal dyshomeostasis and oxidative stress in Alzheimer's disease

Mark A Greenough, James Camakaris, Ashley I Bush

Journal article  |  2013  |  NEUROCHEMISTRY INTERNATIONAL

Copper modulates the large dense core vesicle secretory pathway in PC12 cells

Clare Duncan, Laura Bica, Peter J Crouch, Aphrodite Caragounis, Grace E Lidgerwood, Sarah J Parker, Jodi Meyerowitz, Irene Volitakis, Jeffrey R Liddell, Ravinarayan Raghupathi, Brett M Paterson, Michael D Duffield, Roberto Cappai, Paul S Donnelly, Alexandra Grubman, James Camakaris, Damien J Keating, Anthony R White

Journal article  |  2013  |  Metallomics: integrated biometal science

Copper Transporting P-Type ATPases in the Brain

Sharon La Fontaine, James Camakaris, Julian Mercer

Book Chapter  |  2013

What can flies tell us about copper homeostasis?

Adam Southon, Richard Burke, James Camakaris

Journal article  |  2013  |  Metallomics: integrated biometal science

In silico modeling of the Menkes copper-translocating P-type ATPase 3rd metal binding domain predicts that phosphorylation regulates copper-binding

NA Veldhuis, MJ Kuiper, RCJ Dobson, RB Pearson, J Camakaris

Journal article  |  2011  |  Biometals

Presenilins Promote the Cellular Uptake of Copper and Zinc and Maintain Copper Chaperone of SOD1-dependent Copper/Zinc Superoxide Dismutase Activity

Mark A Greenough, Irene Volitakis, Qiao-Xin Li, Katrina Laughton, Genevieve Evin, Michael Ho, Andrew H Dalziel, James Camakaris, Ashley I Bush

Journal article  |  2011  |  Journal of Biological Chemistry

Copper Promotes the Trafficking of the Amyloid Precursor Protein

Karla M Acevedo, Ya Hui Hung, Andrew H Dalziel, Qiao-Xin Li, Katrina Laughton, Krutika Wikhe, Alan Rembach, Blaine Roberts, Colin L Masters, Ashley I Bush, James Camakaris

Journal article  |  2011  |  JOURNAL OF BIOLOGICAL CHEMISTRY

The ADP-ribosylation factor 1 (Arf1) is involved in regulating copper uptake

Adam Southon, Mark Greenough, Ya Hui Hung, Melanie Norgate, Richard Burke, James Camakaris

Journal article  |  2011  |  International Journal of Biochemistry and Cell Biology

Syntaxin 5 Is Required for Copper Homeostasis in Drosophila and Mammals

Melanie Norgate, Adam Southon, Mark Greenough, Michael Cater, Ashley Farlow, Philip Batterham, Ashley I Bush, V Nathan Subramaniam, Richard Burke, James Camakaris

Journal article  |  2010  |  PLOS ONE

Conservation of copper-transporting P(IB)-type ATPase function

Adam Southon, Nickless Palstra, Nicholas Veldhuis, Ann Gaeth, Charles Robin, Richard Burke, James Camakaris

Journal article  |  2010  |  Biometals

Tissue-specific interplay between copper uptake and efflux in Drosophila

Tim Binks, Jessica Charlotte Lye, James Camakaris, Richard Burke

Journal article  |  2010  |  Journal of Biological Inorganic Chemistry

Control of Alzheimer's Amyloid Beta Toxicity by the High Molecular Weight Immunophilin FKBP52 and Copper Homeostasis in Drosophila

Reiko Sanokawa-Akakura, Weihuan Cao, Kirsten Allan, Khyati Patel, Anupama Ganesh, Gary Heiman, Richard Burke, Francis W Kemp, John D Bogden, James Camakaris, Raymond B Birge, Mary Konsolaki

Journal article  |  2010  |  PLoS One

Bis(thiosemicarbazonato) Cu-64 Complexes for Positron Emission Tomography Imaging of Alzheimer's Disease

Michelle T Fodero-Tavoletti, Victor L Villemagne, Brett M Paterson, Anthony R White, Qiao-Xin Li, James Camakaris, Graeme J O'Keefe, Roberto Cappai, Kevin J Barnham, Paul S Donnelly

Journal article  |  2010  |  Journal of Alzheimer's Disease

Phosphorylation regulates copper-responsive trafficking of the Menkes copper transporting P-type ATPase

Nicholas A Veldhuis, Valentina A Valova, Ann P Gaeth, Nickless Palstra, Katherine M Hannan, Belinda J Michell, Leonard E Kelly, Ian Jennings, Bruce E Kemp, Richard B Pearson, Phillip J Robinson, James Camakaris

Journal article  |  2009  |  International Journal of Biochemistry and Cell Biology

The multi-layered regulation of copper translocating P-type ATPases

Nicholas A Veldhuis, Ann P Gaeth, Richard B Pearson, Kipros Gabriel, James Camakaris

Journal article  |  2009  |  Biometals

Regulation of Prion Gene Expression by Transcription Factors SP1 and Metal Transcription Factor-1

Shayne A Bellingham, Louise A Coleman, Colin L Masters, James Camakaris, Andrew F Hill

Journal article  |  2009  |  Journal of Biological Chemistry

Investigating copper-regulated protein expression in Menkes fibroblasts using antibody microarrays

Tai Du, Sharon L La Fontaine, Michael Abdo, Shayne A Bellingham, Mark Greenough, Irene Volitakis, Robert A Cherny, Ashley I Bush, Peter J Hudson, James Camakaris, Julian F Mercer, Peter J Crouch, Colin L Masters, Victoria M Perreau, Anthony R White

Journal article  |  2008  |  Proteomics - Clinical Applications

ATP7B expression in human breast epithelial cells is mediated by lactational hormones

Agnes Michaiczyk, Edward Bastow, Mark Greenough, James Camakaris, David Freestone, Philip Taylor, Maria Linder, Julian Mercer, Margaret L Ackland

Journal article  |  2008  |  Journal of Histochemistry and Cytochemistry

Malvolio is a copper transporter in Drosophila melanogaster

Adam Southon, Ashley Farlow, Melanie Norgate, Richard Burke, James Camakaris

Journal article  |  2008  |  Journal of Experimental Biology

Expression and localisation of the essential copper transporter DmATP7 in Drosophila neuronal and intestinal tissues

Richard Burke, Elizabeth Commons, James Camakaris

Journal article  |  2008  |  International Journal of Biochemistry and Cell Biology

Mechanisms of A beta mediated neurodegeneration in Alzheimer's disease

Peter J Crouch, Susan-Marie E Harding, Anthony R White, James Camakaris, Ashley I Bush, Colin L Masters

Journal article  |  2008  |  International Journal of Biochemistry and Cell Biology

Hormonal regulation of the Menkes and Wilson copper-transporting ATPases in human placental Jeg-3 cells

Belinda Hardman, Agnes Michalczyk, Mark Greenough, James Camakaris, Julian FB Mercer, M Leigh Ackland

Journal article  |  2007  |  Biochemical Journal

Purification and membrane reconstitution of catalytically active Menkes copper-transporting P-type ATPase (MNK; ATP7A)

Ya Hui Hung, Meredith J Layton, Ilia Voskoboinik, Julian FB Mercer, James Camakaris

Journal article  |  2007  |  Biochemical Journal

Copper homeostasis gene discovery in Drosophila

M NORGATE, A SOUTHON, S Zou, M Zhan, Y Sun, P BATTERHAM, J CAMAKARIS

Journal article  |  2007  |  Biometals

Distinct functional roles for the Menkes and Wilson copper translocating P-type ATPases in human placental cells

Belinda Hardman, Agnes Michalczyk, Mark Greenough, James Camakaris, Julian FB Mercer, M Leigh Ackland

Journal article  |  2007  |  Cellular Physiology and Biochemistry

The use of the zinc-fluorophore, Zinpyr-1, in the study of zinc homeostasis in Arabidopsis roots

Scott A Sinclair, Sarah M Sherson, Renee Jarvis, James Camakaris, Christopher S Cobbett

Journal article  |  2007  |  New Phytologist

Essential roles in development and pigmentation for the Drosophila copper transporter DmATP7

M Norgate, E Lee, A Southon, A Farlow, P Batterham, J Camakaris, R Burke

Journal article  |  2006  |  Molecular Biology of the Cell

Menkes protein localization in rat parotid acinar cells

F D'Amico, E Skarmoutsou, S Sanfilippo, J Camakaris

Journal article  |  2005  |  Acta Histochemica

Signals regulating trafficking of Menkes (MNK; ATP7A) copper-translocating P-type ATPase in polarized MDCK cells

M Greenough, L Pase, I Voskoboinik, MJ Petris, AW O'Brien, J Camakaris

Journal article  |  2004  |  American Journal of Physiology - Cell Physiology

Copper homoeostasis in Drosophila melanogaster S2 cells

A Southon, R Burke, M Norgate, P Batterham, J Camakaris

Journal article  |  2004  |  Biochemical Journal

Gene knockout of amyloid precursor protein and amyloid precursor-like protein-2 increases cellular copper levels in primary mouse cortical neurons and embryonic fibroblasts

SA Bellingham, GD Ciccotosto, BE Needham, LR Fodero, AR White, CL Masters, R Cappai, J Camakaris

Journal article  |  2004  |  Journal of Neurochemistry

Copper depletion down-regulates expression of the Alzheimer's disease amyloid-beta precursor protein gene

SA Bellingham, DK Lahiri, B Maloney, S La Fontaine, G Multhaup, J Camakaris

Journal article  |  2004  |  Journal of Biological Chemistry

P-type ATPase heavy metal transporters with roles in essential zinc homeostasis in Arabidopsis

D Hussain, MJ Haydon, Y Wang, E Wong, SM Sherson, J Young, J Camakaris, JF Harper, CS Cobbett

Journal article  |  2004  |  The Plant Cell

Copper stimulates trafficking of a distinct pool of the Menkes copper ATPase (ATP7A) to the plasma membrane and diverts it into a rapid recycling pool

L Pase, I Voskoboinik, M Greenough, J Camakaris

Journal article  |  2004  |  Biochemical Journal

Copper:the Jekyll and Hyde element

MJ MERCER, J CAMAKARIS

Journal article  |  2004  |  Australian Biochemist

Studies on endocytic mechanisms of the Menkes copper-translocating P-type ATPase (TP7A;MNK)

C LANE, JM PETRIS, A BENMERAH, MA GREENOUGH, J CAMAKARIS

Journal article  |  2004  |  Biometals

P-type pumps:copper pump

I VOSKOBOINIK, J CAMAKARIS

Book Chapter  |  2004

Protein kinase-dependent phosphorylation of the Menkes copper P-type ATPase

I Voskoboinik, R Fernando, N Veldhuis, KM Hannan, N Marmy-Conus, RB Pearson, J Camakaris

Journal article  |  2003  |  Biochemical and Biophysical Research Communications

Mutational analysis of the Menkes copper P-type ATPase (ATP7A)

I Voskoboinik, J Mar, J Camakaris

Journal article  |  2003  |  Biochemical and Biophysical Research Communications

Copper-regulated trafficking of the Menkes disease copper ATPase is associated with formation of a phosphorylated catalytic intermediate

MJ Petris, I Voskoboinik, M Cater, K Smith, BE Kim, RM Llanos, D Strausak, J Camakaris, JFB Mercer

Journal article  |  2002  |  Journal of Biological Chemistry

Correction of the copper transport defect of Menkes patient fibroblasts by expression of two forms of the sheep Wilson ATPase

PJ Lockhart, S La Fontaine, SD Firth, M Greenough, J Camakaris, JFB Mercer

Journal article  |  2002  |  Biochimica et Biophysica Acta-Molecular Basis of Disease

Menkes copper-translocating P-type ATPase (ATP7A): Biochemical and cell biology properties, and role in Menkes disease

I Voskoboinik, J Camakaris

Journal article  |  2002  |  Journal of Bioenergetics and Biomembranes

Occurrence of Cu-ATPase in Dictyostelium: Possible role in resistance to copper

B Burlando, V Evangelisti, F Dondero, G Pons, J Camakaris, A Viarengo

Journal article  |  2002  |  Biochemical and Biophysical Research Communications

Molecular Basis of Diseases of Copper Homeostasis

MJ MERCER, D KRAMER, J CAMAKARIS

Book Chapter  |  2002

Understanding the mechanism and function of copper P-type ATPases

I Voskoboinik, J Camakaris, JFB Mercer

Book Chapter  |  2002  |  Advances in Protein Chemistry

The regulation of catalytic activity of the menkes copper-translocating P-type ATPase - Role of high affinity copper-binding sites

I Voskoboinik, J Mar, D Strausak, J Camakaris

Journal article  |  2001  |  Journal of Biological Chemistry

Functional studies on the Wilson copper P-type ATPase and toxic milk mouse mutant

I Voskoboinik, M Greenough, S La Fontaine, JFB Mercer, J Camakaris

Journal article  |  2001  |  Biochemical and Biophysical Research Communications