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Prof

James Camakaris

Honorary
Biosciences
Copper
Menkes disease
Alzheimers disease
Protein trafficking
confocal microscopy
copper
science & technology
life sciences & biomedicine
animals
James Camakaris's Profile Picture
Prof

James Camakaris

 
Division
Science
 
Primary Interest
Copper homeostasis
James Camakaris's Profile Picture
Prof

James Camakaris

 
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Projects

Displaying the 10 most recent projects by James Camakaris.

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The role of copper in regulating Amyloid Precursor Protein of Alzheimer's disease

Sufferers of Alzheimer's disease have excessive levels of a particular protein (Abeta) as well as a copper imbalance in the brain. It is wid..

2012 - 2015
Completed
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THE ROLE OF COPPER AND ZINC IN DEVELOPMENT OF BLINDNESS IN THE ELDERLY DUE TO MACULAR DEGENERATION

2011 - 2011
Completed
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Improving neuronal cell function with cell permeable copper complexes

Metal-based drugs offer an exciting new approach to treatment of neurodegeneration. However, little is known about how cells metabolise thes..

2011 - 2013
Completed
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APPLICATION OF COPPER-64 IN STUDIES OF THE ROLE OF COPPER IN ALZHEIMER'S DISEASE

2009 - 2009
Completed
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PROTEIN NETWORKS MEDIATING COPPER BALANCE AND THEIR BREAK-DOWN IN DISEASE

Neurological disorders (eg. Alzheimer s, Parkinson s and prion diseases) impose a growing health burden on society. Exciting new therapeutic..

2008 - 2010
Completed
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Copper deficiency in Alzheimer's disease

Alzheimer's disease is a serious neurodegenerative disease which increases in incidence with age. It affects the quality of life and care re..

2007 - 2009
Completed
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COPPER HOMEOSTASIS AND ADD-INDUCED NEURODEGENERATION IN DROSOPHILA

Alzheimer s disease, a debilitating neurodegenerative disorder suffered by many of our elderly, is characterised by the presence of abnormal..

2007 - 2010
Completed
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UTILISATION OF COPPER-64 IN INVESTIGATIONS OF INVOLVEMENT OF COPPER IN ALZHEIMER'S DISEASE

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Localisation and trafficking of copper transporters in retinal pigment epithelium and relevance to major eye disease, macular degeneration

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APPLICATION OF COPPER-64 TO STUDIES ON ALZHEIMER'S DISEASE AND CHARACTERISATION OF NOVEL GENES AND PROTEINS INVOLVED IN COPPER HOMEOSTASIS

Completed

19

Projects

Project Types

16

Research Grant

3

Research Contracts

Scholarly Works

Displaying the 10 most recent scholarly works by James Camakaris.

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Copper comes of age in Melbourne

Julian FB Mercer, James Camakaris

Journal article  |  2016  |  Metallomics

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A commonly used Drosophila model of Alzheimer's disease generates an aberrant species of amyloid-beta with an additional N-terminal glutamine residue

Kirsten Allan, Keyla A Perez, Kevin J Barnham, James Camakaris, Richard Burke

Journal article  |  2014  |  FEBS Letters

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Phosphorylation of Amyloid Precursor Protein at Threonine 668 Is Essential for Its Copper-responsive Trafficking in SH-SY5Y Neuroblastoma Cells

Karla M Acevedo, Carlos M Opazo, David Norrish, Leesa M Challis, Qiao-Xin Li, Anthony R White, Ashley I Bush, James Camakaris

Journal article  |  2014  |  JOURNAL OF BIOLOGICAL CHEMISTRY

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Neuroprotective Copper Bis(thiosemicarbazonato) Complexes Promote Neurite Elongation

Laura Bica, Jeffrey R Liddell, Paul S Donnelly, Clare Duncan, Aphrodite Caragounis, Irene Volitakis, Brett M Paterson, Roberto Cappai, Alexandra Grubman, James Camakaris, Peter J Crouch, Anthony R White

Journal article  |  2014  |  PLOS ONE

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Erratum: Copper modulates the large dense core vesicle secretory pathway in PC12 cells (Metallomics (2013) 5 (700-714) DOI:10.1039/C3MT20231C)

C Duncan, L Bica, PJ Crouch, A Caragounis, GE Lidgerwood, SJ Parker, J Meyerowitz, I Volitakis, JR Liddell, R Raghupathi, BM Paterson, MD Duffield, R Cappai, PS Donnelly, A Grubman, J Camakaris, DJ Keating, AR White

Journal article  |  2013  |  Metallomics

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Presenilin Promotes Dietary Copper Uptake

Adam Southon, Mark A Greenough, George Ganio, Ashley I Bush, Richard Burke, James Camakaris

Journal article  |  2013  |  PLOS ONE

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Metal dyshomeostasis and oxidative stress in Alzheimer's disease

Mark A Greenough, James Camakaris, Ashley I Bush

Journal article  |  2013  |  NEUROCHEMISTRY INTERNATIONAL

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Copper modulates the large dense core vesicle secretory pathway in PC12 cells

Clare Duncan, Laura Bica, Peter J Crouch, Aphrodite Caragounis, Grace E Lidgerwood, Sarah J Parker, Jodi Meyerowitz, Irene Volitakis, Jeffrey R Liddell, Ravinarayan Raghupathi, Brett M Paterson, Michael D Duffield, Roberto Cappai, Paul S Donnelly, Alexandra Grubman, James Camakaris, Damien J Keating, Anthony R White

Journal article  |  2013  |  Metallomics: integrated biometal science

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Copper modulates the large dense core vesicle secretory pathway in PC12 cells (vol 5, pg 700, 2013)

Clare Duncan, Laura Bica, Peter J Crouch, Aphrodite Caragounis, Grace E Lidgerwood, Sarah J Parker, Jodi Meyerowitz, Irene Volitakis, Jeffrey R Liddell, Ravinarayan Raghupathi, Brett M Paterson, Michael D Duffield, Roberto Cappai, Paul S Donnelly, Alexandra Grubman, James Camakaris, Damien J Keating, Anthony R White

Journal article  |  2013  |  METALLOMICS

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Copper Transporting P-Type ATPases in the Brain

Sharon La Fontaine, James Camakaris, Julian Mercer

Book Chapter  |  2013

116

Scholarly Works

Keyword Analysis

Biochemistry and Cell Biology
Expanding Knowledge
Genetics
Non-Oriented Research
Clinical (organs, Diseases and Abnormal Conditions)
Public Health
Neurosciences
Clinical Health (organs, Diseases and Abnormal Conditions)
Medical Biochemistry and Metabolomics
Inorganic Chemistry

Honours, Awards and Fellowships

2008

In recognition of outstanding contributions at the international level to the field of biometals research

IGOR STOJILJKOVIC MEMORIAL AWARD
2000

AINSE gold medal awarded for excellence in research

AINSE

2

Awards

Credentials

Positions

Honorary

Biosciences

Member

American Society for Cell Biology

Member

Human Genetics Society of Australasia

Member

Australian Society of Biochemistry and Molecular Biology

Education

Doctor of Philosophy

University of Melbourne

Bachelor of Science

University of Melbourne