Meryl Davis

Dual DNA binding and coactivator functions of Aspergillus nidulansTamA, a Zn(II)2Cys6 transcription factor

Damien J Downes, Meryl A Davis, Koon Ho Wong, Sara D Kreutzberger, Michael J Hynes, Richard B Todd

Journal article  |  2014  |  Molecular Microbiology

Multiple Nuclear Localization Signals Mediate Nuclear Localization of the GATA Transcription Factor AreA

Cameron C Hunter, Kendra S Siebert, Damien J Downes, Koon Ho Wong, Sara D Kreutzberger, James A Fraser, David F Clarke, Michael J Hynes, Meryl A Davis, Richard B Todd

Journal article  |  2014  |  Eukaryotic Cell

Regulation of the NADP-glutamate dehydrogenase gene gdhA in Aspergillus nidulans by the Zn(II)2Cys6 transcription factor LeuB

Damien J Downes, Meryl A Dayis, Sara D Kreutzberger, Brendan L Taig, Richard B Todd

Journal article  |  2013  |  Microbiology-SGM

Reprogramming of carbon metabolism by the transcriptional activators AcuK and AcuM in Aspergillus nidulans

Yumi Suzuki, Sandra L Murray, Koon Ho Wong, Meryl A Davis, Michael J Hynes

Journal article  |  2012  |  Molecular Microbiology

Role of Carnitine Acetyltransferases in Acetyl Coenzyme A Metabolism in Aspergillus nidulans

Michael J Hynes, Sandra L Murray, Alex Andrianopoulos, Meryl A Davis

Journal article  |  2011  |  Eukaryotic Cell

Aspergillus nidulans contains six possible fatty acyl-CoA synthetases with FaaB being the major synthetase for fatty acid degradation

Kathrin Reiser, Meryl A Davis, Michael J Hynes

Journal article  |  2010  |  Archives of Microbiology

AoxA is a major peroxisomal long chain fatty acyl-CoA oxidase required for beta-oxidation in A. nidulans

Kathrin Reiser, Meryl A Davis, Michael J Hynes

Journal article  |  2010  |  Current Genetics

Nitrogen Metabolism in Filamentous Fungi

Meryl A Davis, Koon Ho Wong

Book Chapter  |  2010

Deletion and overexpression of the Aspergillus nidulans GATA factor AreB reveals unexpected pleiotropy

Koon Ho Wong, Michael J Hynes, Richard B Todd, Meryl A Davis

Journal article  |  2009  |  Microbiology

Recent advances in nitrogen regulation: a comparison between Saccharomyces cerevisiae and filamentous fungi

Koon Ho Wong, Michael J Hynes, Meryl A Davis

Journal article  |  2008  |  Eukaryotic Cell

Sumoylation in Aspergillus nidulans: sumO inactivation, overexpression and live-cell imaging

Koon Ho Wong, Richard B Todd, Berl R Oakley, C Elizabeth Oakley, Michael J Hynes, Meryl A Davis

Journal article  |  2008  |  Fungal Genetics and Biology

Genetic analysis of the role of peroxisomes in the utilization of acetate and fatty acids in Aspergillus nidulans

Michael J Hynes, Sandra L Murray, Gillian S Khew, Meryl A Davis

Journal article  |  2008  |  Genetics

Cloning and sequence characterization of a non-reducing polyketide synthase gene from the lichen Xanthoparmelia semiviridis

Yit-Heng Chooi, David M Stalker, Meryl A Davis, Isao Fujii, John A Elix, Simone HJJ Louwhoff, Ann C Lawrie

Journal article  |  2008  |  Mycological Research

Transcriptional control of nmrA by the bZIP transcription factor MeaB reveals a new level of nitrogen regulation in Aspergillus nidulans

Koon Ho Wong, Michael J Hynes, Richard B Todd, Meryl A Davis

Journal article  |  2007  |  Molecular Microbiology

Transcriptional control of gluconeogenesis in Aspergillus nidulans

Michael J Hynes, Edyta Szewczyk, Sandra L Murray, Yumi Suzuki, Meryl A Davis, Heather M Sealy Lewis

Journal article  |  2007  |  Genetics

Genetic manipulation of Aspergillus nidulans: meiotic progeny for genetic analysis and strain construction

Richard B Todd, Meryl A Davis, Michael J Hynes

Journal article  |  2007  |  Nature Protocols

Genetic manipulation of Aspergillus nidulans: heterokaryons and diploids for dominance, complementation and haploidization analyses

Richard B Todd, Meryl A Davis, Michael J Hynes

Journal article  |  2007  |  Nature Protocols

Regulatory genes controlling fatty acid catabolism and peroxisomal functions in the filamentous fungus Aspergillus nidulans

Michael J Hynes, Sandra L Murray, Anna Duncan, Gillian S Khew, Meryl A Davis

Journal article  |  2006  |  Eukaryotic Cell

Differential expression of Aspergillus nidulans ammonium permease genes is regulated by GATA transcription factor AreA

BJ Monahan, MC Askin, MJ Hynes, MA Davis

Journal article  |  2006  |  Eukaryotic Cell

Nuclear accumulation of the GATA factor AreA in response to complete nitrogen starvation by regulation of nuclear export

RB Todd, JA Fraser, KH Wong, MA Davis, MJ Hynes

Journal article  |  2005  |  Eukaryotic Cell

Amino acid catabolism by an areA-regulated gene encoding an L-amino acid oxidase with broad substrate specificity in Aspergillus nidulans

MA Davis, MC Askin, MJ Hynes

Journal article  |  2005  |  Applied and Environmental Microbiology

TamA interacts with LeuB, the homologue of Saccharomyces cerevisiae Leu3p, to regulate gdhA expression in Aspergillus nidulans

R Polotnianka, BJ Monahan, MJ Hynes, MA Davis

Journal article  |  2004  |  Molecular Genetics and Genomics

Regulation of the amdS Gene in Aspergillus nidulans

M HYNES, M DAVIS

Book Chapter  |  2004

A gene from Aspergillus nidulans with similarity to URE2 of Saccharomyces cerevisiae encodes a glutathione S-transferase which contributes to heavy metal and xenobiotic resistance

JA Fraser, MA Davis, MJ Hynes

Journal article  |  2002  |  Applied and Environmental Microbiology

Mutation and functional analysis of the Aspergillus nidulans ammonium permease MeaA and evidence for interaction with itself and MepA

BJ Monahan, SE Unkles, TT I, JR Kinghorn, MJ Hynes, MA Davis

Journal article  |  2002  |  Fungal Genetics and Biology

The genes gmdA, encoding an amidase, and bzuA, encoding a cytochrome P450, are required for benzamide utilization in Aspergillus nidulans

JA Fraser, MA Davis, MJ Hynes

Journal article  |  2002  |  Fungal Genetics and Biology

Isolation and characterization of two ammonium permease genes, meaA and mepA, from Aspergillus nidulans

BJ Monahan, JA Fraser, MJ Hynes, MA Davis

Journal article  |  2002  |  Eukaryotic Cell

Regulation of the acuF gene, encoding phosphoenolpyruvate carboxykinase in the filamentous fungus Aspergillus nidulans

MJ Hynes, OW Draht, MA Davis

Journal article  |  2002  |  Journal of Bacteriology

A single gene produces mitochondrial, cytoplasmic, and peroxisomal NADP-dependent isocitrate dehydrogenase in Aspergillus nidulans

E Szewczyk, A Andrianopoulos, MA Davis, MJ Hynes

Journal article  |  2001  |  Journal of Biological Chemistry

Role of glutamine synthetase in nitrogen metabolite repression in Aspergillus nidulans

S Margelis, C D'Souza, AJ Small, MJ Hynes, TH Adams, MA Davis

Journal article  |  2001  |  Journal of Bacteriology

Functional analysis of TamA, a coactivator of nitrogen-regulated gene expression in Aspergillus nidulans

AJ Small, RB Todd, MC Zanker, S Delimitrou, MJ Hynes, MA Davis

Journal article  |  2001  |  Molecular Genetics and Genomics

AoHapB, AoHapC and AoHapE, subunits of the Aspergillus oryzae CCAAT-binding complex, are functionally interchangeable with the corresponding subunits in Aspergillus nidulans

A Tanaka, K Kamai, S Tanoue, P Papagiannopoulos, S Steidl, AA Brakhage, MA Davis, MJ Hynes, M Kato, T Kobayashi, N Tsukagoshi

Journal article  |  2001  |  Current Genetics

The formamidase gene of Aspergillus nidulans: Regulation by nitrogen metabolite repression and transcriptional interference by an overlapping upstream gene

JA Fraser, MA Davis, MJ Hynes

Journal article  |  2001  |  Genetics

An Aspergillus oryzae CCAAT-binding protein, AoCP, is involved in the high-level expression of the Taka-amylase A gene.

A Tanaka, M Kato, H Hashimoto, K Kamei, F Naruse, P Papagiannopoulos, MA Davis, MJ Hynes, T Kobayashi, N Tsukagoshi

Journal article  |  2000  |  Current Genetics

Aspergillus oryzae contains a nuclear protein designated AoCP, which binds specifically to a CCAAT sequence in the promoter region..

AnCF, the CCAAT binding complex of Aspergillus nidulans, is essential for the formation of a DNase I-hypersensitive site in the 5' region of the amdS gene.

FM Narendja, MA Davis, MJ Hynes

Journal article  |  1999  |  Molecular and Cellular Biology

The CCAAT sequence in the amdS promoter of Aspergillus nidulans is recognized by AnCF, a complex consisting of the three evolution..

The TamA protein fused to a DNA-binding domain can recruit AreA, the major nitrogen regulatory protein, to activate gene expression in Aspergillus nidulans.

AJ Small, MJ Hynes, MA Davis

Journal article  |  1999  |  Genetics

The areA gene of Aspergillus nidulans encodes a GATA zinc finger transcription factor that activates the expression of a large num..

HAP-Like CCAAT-binding complexes in filamentous fungi: implications for biotechnology.

AA Brakhage, A Andrianopoulos, M Kato, S Steidl, MA Davis, N Tsukagoshi, MJ Hynes

Journal article  |  1999  |  Fungal Genetics and Biology

Regulatory CCAAT boxes are found frequently in eukaryotic promoter regions. They are bound by different CCAAT-binding factors. Unt..

The Aspergillus nidulans gltA gene encoding glutamate synthase is required for ammonium assimilation in the absence of NADP-glutamate dehydrogenase

ML Macheda, MJ Hynes, MA Davis

Journal article  |  1999  |  Current Genetics

AnCF, the CCAAT binding complex of Aspergillus nidulans, contains products of the hapB, hapC, and hapE genes and is required for activation by the pathway-specific regulatory gene amdR.

S Steidl, P Papagiannopoulos, O Litzka, A Andrianopoulos, MA Davis, AA Brakhage, MJ Hynes

Journal article  |  1999  |  Molecular and Cellular Biology

CCAAT binding factors (CBFs) positively regulating the expression of the amdS gene (encoding acetamidase) and two penicillin biosy..

The facC gene of Aspergillus nidulans encodes an acetate-inducible carnitine acetyltransferase.

CJ Stemple, MA Davis, MJ Hynes

Journal article  |  1998  |  Journal of Bacteriology

Mutations in the facC gene of Aspergillus nidulans result in an inability to use acetate as a sole carbon source. This gene has be..

Role of the regulatory gene areA of Aspergillus oryzae in nitrogen metabolism.

T Christensen, MJ Hynes, MA Davis

Journal article  |  1998  |  Applied and Environmental Microbiology

The areA gene of Aspergillus oryzae was cloned by cross-hybridization with the Aspergillus nidulans areA gene and was found to enc..

Characterization of the Aspergillus nidulans nmrA gene involved in nitrogen metabolite repression.

A Andrianopoulos, S Kourambas, JA Sharp, MA Davis, MJ Hynes

Journal article  |  1998  |  Journal of Bacteriology

The gene nmrA of Aspergillus nidulans has been isolated and found to be a homolog of the Neurospora crassa gene nmr-1, involved in..

FacB, the Aspergillus nidulans activator of acetate utilization genes, binds dissimilar DNA sequences.

RB Todd, A Andrianopoulos, MA Davis, MJ Hynes

Journal article  |  1998  |  The EMBO Journal

The facB gene is required for acetate induction of acetamidase (amdS) and the acetate utilization enzymes acetyl-CoA synthase (fac..

The Aspergillus nidulans CCAAT-binding factor AnCP/AnCF is a heteromeric protein analogous to the HAP complex of Saccharomyces cerevisiae.

M Kato, A Aoyama, F Naruse, Y Tateyama, K Hayashi, M Miyazaki, P Papagiannopoulos, MA Davis, MJ Hynes, T Kobayashi, N Tsukagoshi

Journal article  |  1998  |  Molecular and General Genetics MGG

The Aspergillus nidulans hapC gene was expressed as a fusion protein with MalE or glutathione-S-transferase (GST) in Escherichia c..

The penicillin regulator PENR1 of Aspergillus nidulans is a HAP-like transcriptional complex.

O Litzka, P Papagiannopolous, MA Davis, MJ Hynes, AA Brakhage

Journal article  |  1998  |  European Journal of Biochemistry

In Aspergillus nidulans, a DNA-binding complex, PENR1, was shown to bind to two CCAAT-box-containing DNA elements located in the p..

Molecular characterization of mutants of the acetate regulatory gene facB of Aspergillus nidulans.

RB Todd, JM Kelly, MA Davis, MJ Hynes

Journal article  |  1997  |  Fungal Genetics and Biology

The facB gene of Aspergillus nidulans encodes a DNA binding transcriptional activator required for growth on acetate as a sole car..

The acetate regulatory gene facB of Aspergillus nidulans encodes a Zn(II)2Cys6 transcriptional activator.

RB Todd, RL Murphy, HM Martin, JA Sharp, MA Davis, ME Katz, MJ Hynes

Journal article  |  1997  |  Molecular and General Genetics MGG

Genetic studies have indicated that the facB gene of Aspergillus nidulans is a major regulatory gene involved in acetamide and ace..

Identification of amdX, a new Cys-2-His-2 (C2H2) zinc-finger gene involved in the regulation of the amdS gene of Aspergillus nidulans.

RL Murphy, A Andrianopoulos, MA Davis, MJ Hynes

Journal article  |  1997  |  Molecular Microbiology

The acetamidase-encoding amdS gene of Aspergillus nidulans has been shown to be controlled by multiple regulatory genes. A new gen..

The amdA regulatory gene of Aspergillus nidulans: characterization of gain-of-function mutations and identification of binding sites for the gene product.

A Andrianopoulos, J Brons, MA Davis, MJ Hynes

Journal article  |  1997  |  Fungal Genetics and Biology

Genetic evidence suggests that the amdA gene of Aspergillus nidulans encodes a protein which controls the expression of the amdS a..

The hapC gene of Aspergillus nidulans is involved in the expression of CCAAT-containing promoters.

P Papagiannopoulos, A Andrianopoulos, JA Sharp, MA Davis, MJ Hynes

Journal article  |  1996  |  Molecular and General Genetics MGG

The 5' regulatory region of the amdS gene of Aspergillus nidulans, which encodes an acetamidase required for growth on acetamide a..

The tamA gene of Aspergillus nidulans contains a putative zinc cluster motif which is not required for gene function.

MA Davis, AJ Small, S Kourambas, MJ Hynes

Journal article  |  1996  |  Journal of bacteriology

Expression of many nitrogen catabolic enzymes is controlled by nitrogen metabolite repression in Aspergillus nidulans. Although th..

Characterization of the ugatA gene of Ustilago maydis, isolated by homology to the gatA gene of Aspergillus nidulans.

MJ Straffon, MJ Hynes, MA Davis

Journal article  |  1996  |  Current Genetics

A gene encoding a putative GABA aminotransferase (ugatA) was isolated from the basidiomycete Ustilago maydis via heterologous hybr..

The nitrate and nitrite reductase-encoding genes of Leptosphaeria maculans are closely linked and transcribed in the same direction.

RS Williams, MA Davis, BJ Howlett

Journal article  |  1995  |  Gene

The 5' flanking region and the first 704 bp of the nitrite reductase-encoding gene (niiA) of Leptosphaeria maculans has been seque..

The positively acting amdA gene of Aspergillus nidulans encodes a protein with two C2H2 zinc-finger motifs.

R Lints, MA Davis, MJ Hynes

Journal article  |  1995  |  Molecular Microbiology

Semi-dominant mutations in the amdA gene lead to elevated expression of the gene encoding acetamidase, amdS. These mutations also ..

Yeast proteins can activate expression through regulatory sequences of the amdS gene of Aspergillus nidulans.

N Bonnefoy, J Copsey, MJ Hynes, MA Davis

Journal article  |  1995  |  Molecular and General Genetics MGG

The upstream regulatory region of the amdS gene of Aspergillus nidulans contains a CCAAT sequence known to be important in setting..

Nitrate reductase of the ascomycetous fungus, Leptosphaeria maculans: gene sequence and chromosomal location.

RS Williams, MA Davis, BJ Howlett

Journal article  |  1994  |  Molecular and General Genetics MGG

The nitrate reductase (niaD) gene was isolated from the phytopathogenic loculoascomycete Leptosphaeria maculans by screening a gen..

Fungal catabolic gene regulation: molecular genetic analysis of the amdS gene of Aspergillus nidulans.

MA Davis, JM Kelly, MJ Hynes

Journal article  |  1993  |  Genetica

Aspergillus nidulans is an excellent experimental organism for the study of gene regulation. Genetic and molecular analyses of tra..

Structural and functional analysis of the amdR regulatory gene of Aspergillus oryzae.

XW Wang, MJ Hynes, MA Davis

Journal article  |  1992  |  Gene

We have isolated the Aspergillus oryzae homologue of the amdR regulatory gene of Aspergillus nidulans by cross hybridization. Sequ..

IDENTIFICATION OF FUNCTIONAL REGIONS OF THE POSITIVELY ACTING REGULATORY GENE AMDR FROM ASPERGILLUS-NIDULANS

LM PARSONS, MA DAVIS, MJ HYNES

Journal article  |  1992  |  Molecular Microbiology

Regulatory genes in Aspergillus nidulans.

MA Davis, MJ Hynes

Journal article  |  1989  |  Trends in Genetics

A major area for the study of gene regulation in lower eukaryotes has been the coordinated control of catabolic enzyme synthesis. ..

An amdS-lacZ fusion for studying gene regulation in Aspergillus.

MA Davis, CS Cobbett, MJ Hynes

Journal article  |  1988  |  Gene

A translational fusion has been constructed between the amdS gene of Aspergillus nidulans and the lacZ gene of Escherichia coli. S..

Complementation of areA- regulatory gene mutations of Aspergillus nidulans by the heterologous regulatory gene nit-2 of Neurospora crassa.

MA Davis, MJ Hynes

Journal article  |  1987  |  Proceedings of the National Academy of Sciences

Loss-of-function mutations in the regulatory gene areA of Aspergillus nidulans prevent the utilization of a wide variety of nitrog..

The amdS gene of Aspergillus nidulans: control by multiple regulatory signals.

MJ Hynes, MA Davis

Journal article  |  1986  |  BioEssays

COMPARISON OF SUBSTRATE-SPECIFICITY OF MYOSIN KINASE AND CYCLIC AMP-DEPENDENT PROTEIN-KINASE

RB PEARSON, S FORREST, M DAVIS, TJ MARTIN, BE KEMP

Journal article  |  1984  |  Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology