Mehrdad Nikfarjam

Inhibition of PAK1 suppresses pancreatic cancer by stimulation of anti-tumour immunity through down-regulation of PD-L1.

Kai Wang, Yifan Zhan, Nhi Huynh, Chelsea Dumesny, Xiao Wang, Khashayer Asadi, David Herrmann, Paul Timpson, Yang Yang, Katrina Walsh, Graham S Baldwin, Mehrdad Nikfarjam, Hong He

Journal article  |  2020  |  Cancer Letters

Immunotherapies have not yielded significant clinical benefits for pancreatic ductal adenocarcinoma (PDA) because of the existence..

Health economic implications of postoperative complications following liver resection surgery: a systematic review.

Luka Cosic, Ronald Ma, Leonid Churilov, Mehrdad Nikfarjam, Christopher Christophi, Laurence Weinberg

Journal article  |  2019  |  ANZ Journal of Surgery

BACKGROUND: Limited data exists concerning the health economics of liver resection, with even less information on the costs emergi..

Genomic Profiling of Biliary Tract Cancer Cell Lines Reveals Molecular Subtypes and Actionable Drug Targets

David K Lau, Dmitri Mouradov, Wiphawan Wasenang, Ian Y Luk, Cameron M Scott, David S Williams, Yvonne H Yeung, Temduang Limpaiboon, George F Iatropoulos, Laura J Jenkins, Camilla M Reehorst, Fiona Chionh, Mehrdad Nikfarjam, Daniel Croagh, Amardeep S Dhillon, Andrew J Weickhardt, Toshihide Muramatsu, Yoshimasa Saito, Niall C Tebbutt, Oliver M Sieber, et al.

Journal article  |  2019  |  iScience

Biliary tract cancers (BTCs) currently have no approved targeted therapies. Although genomic profiling of primary BTCs has identif..

Incidence and predictors of common bile duct stones in patients with acute cholecystitis: a systematic literature review and meta-analysis

Hongyi Chen, Robert Jorissen, James Walcott, Mehrdad Nikfarjam

Journal article  |  2019  |  ANZ Journal of Surgery

BACKGROUND: Acute cholecystitis (AC) is a surgical condition that is usually managed by emergency surgery. The presence of common ..

How can digital health be used to improve outcomes in pancreatic ductal adenocarcinoma (PDAC)? Examining the potential of the PURPLE translational pancreatic cancer platform

Belinda Lee, Julia Shapiro, Benjamin Thomson, Sumitra Ananda, Lara Lipton, Sue-Anne McLachlan, Rachel Wong, Prasad Cooray, Matthew Burge, Kate Clarke, Sharon Pattison, Mehrdad Nikfarjam, Niall Tebbutt, Marion Harris, Daniel Croagh, David Goldstein, Adnan Nagrial, Rob Zielinski, Amitesh Roy, Cheng Ean Chee, et al.

Conference Proceedings  |  2019  |  ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY

Genetic characteristics of participants in the Australian Pancreatic Screening Study

K Murali, A Collins, L Salmon, M Nikfarjam, T John

Conference Proceedings  |  2019  |  ANNALS OF ONCOLOGY

Quantitation and chemical coding of enteroendocrine cell populations in the human jejunum.

Therese E Fazio Coles, Linda J Fothergill, Billie Hunne, Mehrdad Nikfarjam, Adam Testro, Brid Callaghan, Rachel M McQuade, John B Furness

Journal article  |  2019  |  Cell and Tissue Research

Recent studies reveal substantial species and regional differences in enteroendocrine cell (EEC) populations, including difference..

Circulating tumor DNA as a potential marker of adjuvant chemotherapy benefit following surgery for localized pancreatic cancer

B Lee, L Lipton, J Cohen, J Tie, AA Javed, L Li, D Goldstein, M Burge, P Cooray, A Nagrial, NC Tebbutt, B Thomson, M Nikfarjam, M Harris, A Haydon, B Lawrence, DWM Tai, K Simons, AM Lennon, CL Wolfgang, et al.

Journal article  |  2019  |  Annals of Oncology

BACKGROUND: In early-stage pancreatic cancer, there are currently no biomarkers to guide selection of therapeutic options. This pr..

Goal directed fluid therapy for major liver resection: A multicentre randomized controlled trial

Laurence Weinberg, Damian Ianno, Leonid Churilov, Steven Mcguigan, Lois Mackley, Jonathan Banting, Shi Hong Shen, Bernhard Riedel, Mehrdad Nikfarjam, Chris Christophi

Journal article  |  2019  |  Annals of Medicine and Surgery

Background: The effect a restrictive goal directed therapy (GDT) fluid protocol combined with an enhanced recovery after surgery (..

The Upper Gastrointestinal Cancer Registry (UGICR): a clinical quality registry to monitor and improve care in upper gastrointestinal cancers

Ashika D Maharaj, Jennifer F Holland, Ri O Scarborough, Sue M Evans, Liane J Ioannou, Wendy Brown, Daniel G Croagh, Charles HC Pilgrim, James G Kench, Lara R Lipton, Trevor Leong, John J McNeil, Mehrdad Nikfarjam, Ahmad Aly, Paul R Burton, Paul A Cashin, Julie Chu, Cuong P Duong, Peter Evans, David Goldstein, et al.

Journal article  |  2019  |  BMJ Open

PURPOSE: The Upper Gastrointestinal Cancer Registry (UGICR) was developed to monitor and improve the quality of care provided to p..

CAF hierarchy driven by pancreatic cancer cell p53-status creates a pro-metastatic and chemoresistant environment via perlecan

Claire Vennin, Pauline Melenec, Romain Rouet, Max Nobis, Aurelie S Cazet, Kendelle J Murphy, David Herrmann, Daniel A Reed, Morghan C Lucas, Sean C Warren, Zehra Elgundi, Mark Pinese, Gabriella Kalna, Daniel Roden, Monisha Samuel, Anaiis Zaratzian, Shane T Grey, Andrew Da Silva, Wilfred Leung, Suresh Mathivanan, et al.

Journal article  |  2019  |  Nature Communications

Impact of a goal directed fluid therapy algorithm on postoperative morbidity in patients undergoing open right hepatectomy: a single centre retrospective observational study

Laurence Weinberg, Lois Mackley, Alexander Ho, Steven Mcguigan, Damian Ianno, Matthew Yii, Jonathan Banting, Vijayragavan Muralidharan, Chong Oon Tan, Mehrdad Nikfarjam, Chris Christophi

Journal article  |  2019  |  BMC Anesthesiology

BACKGROUND: Right hepatectomy is a complex procedure that carries inherent risks of perioperative morbidity. To evaluate outcome d..

The financial impact of postoperative complications following liver resection.

Luka Cosic, Ronald Ma, Leonid Churilov, David Debono, Mehrdad Nikfarjam, Christopher Christophi, Laurence Weinberg

Journal article  |  2019  |  Medicine

The aim of the study was to determine the financial burden of complications and examine the cost differentials between complicated..

Outcomes of central hepatectomy versus extended hepatectomy

Jenny Chan, Luke Bradshawa, Nezor Houli, Laurence Weinberg, Marcos Perini, Michael Fink, Vijayaragavan Muralidharan, Graham Starkey, Robert Jones, Bao Zhong Wang, Christopher Christophi, Mehrdad Nikfarjam

Journal article  |  2019  |  Hepatobiliary & Pancreatic Diseases International

PanCO: An open-label, single-arm pilot study of phosphorus-32 (P-32; Oncosil) microparticles in patients with unresectable locally advanced pancreatic adenocarcinoma (LAPC) in combination with FOLFIRINOX or gemcitabine plus nab-paclitaxel (GNP) chemotherapies.

Paul J Ross, Daniel Croagh, Morteza Aghmesheh, Adnan Nagrial, Nguyen Nam, Mehrdad Nikfarjam, Harpreet Singh Wasan, Thankamma V Ajithkumar, Chinenye Iwuji, Alain Hendlisz, Thomas Maher, Anna Kraszewski, Marion Harris

Conference Proceedings  |  2019  |  Journal of Clinical Oncology

Antitumor effects of all-trans retinoic acid and its synergism with gemcitabine are associated with downregulation of p21-activated kinases in pancreatic cancer

Kai Wang, Graham S Baldwin, Mehrdad Nikfarjam, Hong He

Journal article  |  2019  |  American Journal of Physiology-Gastrointestinal and Liver Physiology

Monitoring quality of care for patients with pancreatic cancer: a modified Delphi consensus

Ashika D Maharaj, Liane Ioannou, Daniel Croagh, John Zalcberg, Rachel E Neale, David Goldstein, Neil Merrett, James G Kench, Kate White, Charles HC Pilgrim, Lorraine Chantrill, Peter Cosman, Andrew Kneebone, Lara Lipton, Mehrdad Nikfarjam, Jennifer Philip, Charbel Sandroussi, Peter Tagkalidis, Richard Chye, Koroush S Haghighi, et al.

Journal article  |  2019  |  HPB

Potential Use of Cannabinoids for the Treatment of Pancreatic Cancer

Golnaz Sharafi, Hong He, Mehrdad Nikfarjam

Journal article  |  2019  |  Journal of Pancreatic Cancer

Background: Cannabinoid extracts may have anticancer properties, which can improve cancer treatment outcomes. The aim of this revi..

PAK inhibition by PF-3758309 enhanced the sensitivity of multiple chemotherapeutic reagents in patient-derived pancreatic cancer cell lines

Kai Wang, Huynh Nhi, Xiao Wang, Marina Pajic, Ashleigh Parkin, Jennifer Man, Graham S Baldwin, Mehrdad Nikfarjam, Hong He

Journal article  |  2019  |  American Journal of Translational Research

Pancreatic cancer

David Burnett, Mehrdad Nikfarjam

Book Chapter  |  2019

Emergency presentations of acute biliary pain: changing patterns of management in a tertiary institute

Daniel RA Cox, Jonathan Fong, Chon Hann Liew, Su Kah Goh, Michael Yeoh, Michael A Fink, Robert M Jones, Jude Mukkadayil, Mehrdad Nikfarjam, Marcos V Perini, Greg Rumler, Graham Starkey, Chris Christophi, Vijayaragavan Muralidharan

Journal article  |  2018  |  ANZ Journal of Surgery

Functions of the CXC ligand family in the pancreatic tumor microenvironment

Nien-Hung Lee, Mehrdad Nikfarjam, Hong He

Journal article  |  2018  |  Pancreatology

p21-activated kinase signalling in pancreatic cancer: New insights into tumour biology and immune modulation

Kai Wang, Graham S Baldwin, Mehrdad Nikfarjam, Hong He

Journal article  |  2018  |  World Journal of Gastroenterology

Metastatic clear cell renal cell carcinoma demonstrating intense uptake on 68Ga-DOTATATE positron emission tomography: Three case reports and a review of the literature.

David P Nadebaum, Sze Ting Lee, Mehrdad Nikfarjam, Andrew M Scott

Journal article  |  2018  |  World Journal of Nuclear Medicine

68Ga-DOTATATE positron emission tomography (PET) is a molecular imaging technology which has shown superiority over 111In-octreoti..

C-Reactive Protein Before Liver Transplantation is Predictive of Post-Transplant Mortality

Michael Fink, Graham Starkey, Marcos Perini, Bao-Zhong Wang, Christopher Christophi, Vijaragavan Muralidharan, Mehrdad Nikfarjam, Robert M Jones

Conference Proceedings  |  2018  |  Transplantation

Prediction of Outcome of Donation after Circulatory Death Liver Transplantation - The Concept of Hypotension Exposure

Michael A Fink, Georgina Riddiough, Graham Starkey, Marcos V Perini, Bao-Zhong Wang, Christopher Christophi, Mehrdad Nikfarjam, Vijayaragavan Muralidharan, Robert M Jones

Conference Proceedings  |  2018  |  Transplantation

The outcomes of central hepatectomy versus extended hepatectomy: a systematic review and meta-analysis

Jenny Chan, Marcos Perini, Michael Fink, Mehrdad Nikfarjam

Journal article  |  2018  |  HPB

Health economic implications of complications associated with pancreaticoduodenectomy at a University Hospital: a retrospective cohort cost study

Jason Wang, Ronald Ma, Paul Eleftheriou, Leonid Churilov, David Debono, Ray Robbins, Mehrdad Nikfarjam, Chris Christophi, Laurence Weinberg

Journal article  |  2018  |  HPB

Age 80 years and over is not associated with increased morbidity and mortality following pancreaticoduodenectomy

Sandy Y Kim, Michael A Fink, Marcos Perini, Nezor Houli, Laurence Weinberg, Vijayaragavan Muralidharan, Graham Starkey, Robert M Jones, Christopher Christophi, Mehrdad Nikfarjam

Journal article  |  2018  |  ANZ Journal of Surgery

The cost of perioperative complications following pancreaticoduodenectomy: A systematic review

Jason Wang, Ronald Ma, Leonid Churilov, Paul Eleftheriou, Mehrdad Nikfarjam, Christopher Christophi, Laurence Weinberg

Journal article  |  2018  |  Pancreatology

Inhibition of p21 activated kinase enhances tumour immune response and sensitizes pancreatic cancer to gemcitabine

Kai Wang, Huynh Nhi, Xiao Wang, Graham Baldwin, Mehrdad Nikfarjam, Hong He

Journal article  |  2018  |  International Journal of Oncology

Identification of unique neoantigen qualities in long-term survivors of pancreatic cancer

Vinod P Balachandran, Marta Luksza, Julia N Zhao, Vladimir Makarov, John Alec Moral, Romain Remark, Brian Herbst, Gokce Askan, Umesh Bhanot, Yasin Senbabaoglu, Daniel K Wells, Charles Ian Ormsby Cary, Olivera Grbovic-Huezo, Marc Attiyeh, Benjamin Medina, Jennifer Zhang, Jennifer Loo, Joseph Saglimbeni, Mohsen Abu-Akeel, Roberta Zappasodi, et al.

Journal article  |  2017  |  Nature

Diagnosis and treatment in chronic pancreatitis: an international survey and case vignette study

Yama Issa, Hjalmar C van Santvoort, Paul Fockens, Marc G Besselink, Thomas L Bollen, Marco J Bruno, Marja A Boermeester

Journal article  |  2017  |  HPB

Restrictive intraoperative fluid optimisation algorithm improves outcomes in patients undergoing pancreaticoduodenectomy: A prospective multicentre randomized controlled trial

Laurence Weinberg, Damian Ianno, Leonid Churilov, Ian Chao, Nick Scurrah, Clive Rachbuch, Jonathan Banting, Vijaragavan Muralidharan, David Story, Rinaldo Bellomo, Chris Christophi, Mehrdad Nikfarjam

Journal article  |  2017  |  PLOS ONE

The effect of a surgery-specific cardiac output-guided haemodynamic algorithm on outcomes in patients undergoing pancreaticoduodenectomy in a high-volume centre: a retrospective comparative study

L Weinberg, J Banting, L Churilov, RL McLeod, K Fernandes, I Chao, T Ho, D Ianno, V Liang, V Muralidharan, C Christophi, M Nikfarjam

Journal article  |  2017  |  Anaesthesia and Intensive Care

K-Ras mutation and amplification status is predictive of resistance and high basal pAKT is predictive of sensitivity to everolimus in biliary tract cancer cell lines

Yvonne Yeung, David K Lau, Fiona Chionh, Hoanh Tran, Janson WT Tse, Andrew J Weickhardt, Mehrdad Nikfarjam, Andrew M Scott, Niall C Tebbutt, John M Mariadason

Journal article  |  2017  |  Molecular Oncology

Diagnosis and management of pancreatic exocrine insufficiency

Mehrdad Nikfarjam, Jeremy S Wilson, Ross C Smith

Journal article  |  2017  |  Medical Journal of Australia

Diagnosis and management of pancreatic exocrine insufficiency

M Nikfarjam, JS Wilson, RC Smith

Journal article  |  2017  |  Medical Journal of Australia

Depletion of p21-activated kinase 1 up-regulates the immune system of APC(Delta 14/ ) mice and inhibits intestinal tumorigenesis

Nhi Huynh, Kai Wang, Mildred Yim, Chelsea J Dumesny, Mauro S Sandrin, Graham S Baldwin, Mehrdad Nikfarjam, Hong He

Journal article  |  2017  |  BMC Cancer

The outcomes of pancreaticoduodenectomy in patients aged 80 or older: a systematic review and meta-analysis

Sandy Y Kim, Laurence Weinberg, Christopher Christophil, Mehrdad Nikfarjam

Journal article  |  2017  |  HPB

Inhibition of Group 1 p21-Activated Kinases Suppresses Pancreatic Stellate Cell Activation and Increases Survival of Mice with Pancreatic Cancer

Dannel Yeo, Phoebe Phillips, Graham S Baldwin, Hong He, Mehrdad Nikfarjam

Journal article  |  2017  |  International Journal of Cancer

Refining the care of patients with pancreatic cancer: the AGITG Pancreatic Cancer Workshop consensus

Robert C Gandy, Andrew P Barbour, Jaswinder Samra, Mehrdad Nikfarjam, Koroush Haghighi, James G Kench, Payal Saxena, David Goldstein

Journal article  |  2016  |  MEDICAL JOURNAL OF AUSTRALIA

Refining the care of patients with pancreatic cancer: the AGITG Pancreatic Cancer Workshop consensus

Robert C Gandy, Andrew P Barbour, Jaswinder Samra, Mehrdad Nikfarjam, Koroush Haghighi, James G Kench, Payal Saxena, David Goldstein

Journal article  |  2016  |  The Medical Journal of Australia

Sodium bicarbonate infusion in patients undergoing orthotopic liver transplantation: a single center randomized controlled pilot trial

Laurence Weinberg, Jeremy Broad, Param Pillai, Guangjun Chen, Micheline Nguyen, Glenn M Eastwood, Nick Scurrah, Mehrdad Nikfarjam, David Story, Larry McNicol, Rinaldo Bellomo

Journal article  |  2016  |  Clinical Transplantation

Genomic analyses identify molecular subtypes of pancreatic cancer

Peter Bailey, David K Chang, Katia Nones, Amber L Johns, Ann-Marie Patch, Marie-Claude Gingras, David K Miller, Angelika N Christ, Tim JC Bruxner, Michael C Quinn, Craig Nourse, L Charles Murtaugh, Ivon Harliwong, Senel Idrisoglu, Suzanne Manning, Ehsan Nourbakhsh, Shivangi Wani, Lynn Fink, Oliver Holmes, Vencssa Chin, et al.

Journal article  |  2016  |  Nature

Summary and recommendations from the Australasian guidelines for the management of pancreatic exocrine insufficiency

Ross C Smith, Sarah F Smith, Jeremy Wilson, Callum Pearce, Nick Wray, Ruth Vo, John Chen, Chee Y Ooi, Mark Oliver, Tamarah Katz, Richard Turner, Mehrdad Nikfarjam, Christopher Rayner, Michael Horowitz, Gerald Holtmann, Nick Talley, John Windsor, Ron Pirola, Rachel Neale

Journal article  |  2016  |  Pancreatology

PANCREATIC CANCER: IS THE SURGEON STILL RELEVANT?

Nick Butler, Jaswinder Samra, Mehrdad Nikfarjam, Andrew P Barbour

Journal article  |  2016  |  Cancer Forum

Ampullary Cancers Harbor ELF3 Tumor Suppressor Gene Mutations and Exhibit Frequent WNT Dysregulation

Marie-Claude Gingras, Kyle R Covington, David K Chang, Lawrence A Donehower, Anthony J Gill, Michael M Ittmann, Chad J Creighton, Amber L Johns, Eve Shinbrot, Ninad Dewal, William E Fisher, Christian Pilarsky, Robert Gruetzmann, Michael J Overman, Nigel B Jamieson, George Van Buren, Jennifer Drummond, Kimberly Walker, Oliver A Hampton, Liu Xi, et al.

Journal article  |  2016  |  Cell Reports

Intraoperative analysis of cross-talk inhibition between diaphragmatic and cardiac pacemakers.

Katrina Fernandes, Ruth Louise McLeod, Mehrdad Nikfarjam, Laurence Weinberg

Journal article  |  2016  |  BMJ Case Reports

FRAX597, a PAK1 inhibitor, synergistically reduces pancreatic cancer growth when combined with gemcitabine

Dannel Yeo, Hong He, Oneel Patel, Andrew M Lowy, Graham S Baldwin, Mehrdad Nikfarjam

Journal article  |  2016  |  BMC Cancer

Glaucarubinone Combined with Gemcitabine Improves Pancreatic Cancer Survival in an Immunocompetent Orthotopic Murine Model

Dannel Yeo, Huynh Nhi, John A Beutler, Graham S Baldwin, Hong He, Mehrdad Nikfarjam

Journal article  |  2016  |  Journal of Investigative Surgery

The effects of plasmalyte-148 vs. Hartmann's solution during major liver resection: a multicentre, double-blind, randomized controlled trial

L Weinberg, B Pearce, R Sullivan, L Siu, N Scurrah, C Tan, M Backstrom, M Nikfarjam, L McNicol, D Story, C Christophi, R Bellomo

Journal article  |  2015  |  Minerva Anestesiologica

Meta-analysis of radical resection rates and margin assessment in pancreatic cancer

MD Chandrasegaram, D Goldstein, J Simes, V Gebski, JG Kench, AJ Gill, JS Samra, ND Merrett, AJ Richardson, AP Barbour

Journal article  |  2015  |  British Journal of Surgery

Postoperative wristwatch-induced compressive neuropathy of the hand: a case report.

Laurence Weinberg, Manfred Spanger, Chong Tan, Mehrdad Nikfarjam

Journal article  |  2015  |  Journal of Medical Case Reports

INTRODUCTION: Postoperative peripheral nerve injuries are well-recognised complications of both surgery and anaesthesia and a lead..

FRAX597, a PAK1 inhibitor, synergises with gemcitabine in the reduction of pancreatic cancer growth

D Yeo, H He, G Baldwin, M Nikfarjam

Conference Proceedings  |  2015  |  Annals of Oncology

Diffuse Pancreatic Mucinous Cystic Neoplasm Treated by Total Pancreatectomy

Hongyi Chen, Julie Teague, Laurence Weinberg, Mehrdad Nikfarjam

Journal article  |  2015  |  Journal of the Pancreas

The Role of p21-Activated Kinases in Pancreatic Cancer

Dannel Yeo, Hong He, Graham S Baldwin, Mehrdad Nikfarjam

Journal article  |  2015  |  Pancreas

Results of pancreatic resection associated with portal vein resection in an Australian tertiary care centre

Dragos G Iorgulescu, Sophia Ling, Mehrdad Nikfarjam, Michael A Fink, Robert Jones, Vijayaragavan Muralidharan, Graham Starkey, Christopher Christophi

Journal article  |  2015  |  ANZ Journal of Surgery

Whole genomes redefine the mutational landscape of pancreatic cancer

Nicola Waddell, Marina Pajic, Ann-Marie Patch, David K Chang, Karin S Kassahn, Peter Bailey, Amber L Johns, David Miller, Katia Nones, Kelly Quek, Michael CJ Quinn, Alan J Robertson, Muhammad ZH Fadlullah, Tim JC Bruxner, Angelika N Christ, Ivon Harliwong, Senel Idrisoglu, Suzanne Manning, Craig Nourse, Ehsan Nourbakhsh, et al.

Journal article  |  2015  |  Nature

Somatostatinoma of the Minor Papilla Treated by Local Excision in a Patient with Neurofibromatosis Type 1

Ramesh Bhandari, Georgina Riddiough, Julie Lokan, Laurence Weinberg, Marios Efthymiou, Mehrdad Nikfarjam

Journal article  |  2015  |  Journal of the Pancreas

Assessment of Liver Remnant Using ICG Clearance Intraoperatively during Vascular Exclusion: Early Experience with the ALIIVE Technique.

Lawrence Lau, Christopher Christophi, Mehrdad Nikfarjam, Graham Starkey, Mark Goodwin, Laurence Weinberg, Loretta Ho, Vijayaragavan Muralidharan

Journal article  |  2015  |  HPB Surgery

Background. The most significant risk following major hepatectomy is postoperative liver insufficiency. Current preoperative asses..

Outcomes of cholecystectomy for treatment of acute cholecystitis in octogenarians

Mehrdad Nikfarjam, David Yeo, Marcos Perini, Michael A Fink, Vijayaragavan Muralidharan, Graham Starkey, Robert M Jones, Christopher Christophi

Journal article  |  2014  |  ANZ Journal of Surgery

Total pancreatectomy for the treatment of pancreatic neoplasms

Mehrdad Nikfarjam, Nicholas Low, Laurence Weinberg, Ping Han Chia, Hong He, Christopher Christophi

Journal article  |  2014  |  ANZ Journal of Surgery

Association of Diabetes Mellitus and Pancreatic Adenocarcinoma: A Meta-Analysis of 88 Studies

Pikli Batabyal, Stephen Vander Hoorn, Christopher Christophi, Mehrdad Nikfarjam

Journal article  |  2014  |  Annals of Surgical Oncology

Glucagon-like peptide 1 and peptide YY are in separate storage organelles in enteroendocrine cells

Hyun-Jung Cho, Eliza S Robinson, Leni R Rivera, Paul J McMillan, Adam Testro, Mehrdad Nikfarjam, David M Bravo, John B Furness

Journal article  |  2014  |  Cell and Tissue Research

Laparoscopic Partial Splenectomy Performed by Monopolar Saline-Cooled Radiofrequency Coagulation

Nagendra Naidu Dudi-Venkata, Nezor Houli, Laurence Weinberg, Mehrdad Nikfarjam

Journal article  |  2014  |  Journal of Laparoendoscopic and Advanced Surgical Techniques

Fluid prescription practices of anesthesiologists managing patients undergoing elective colonoscopy: an observational study.

Laurence Weinberg, Matthew Faulkner, Chong O Tan, Daniel H Liu, Stanley Tay, Mehrdad Nikfarjam, Philip Peyton, David Story

Journal article  |  2014  |  BMC Research Notes

BACKGROUND: Routine fluid prescription is common practice amongst anesthesiologists caring for patients undergoing colonoscopy. Ho..

The impact of fluid intervention on complications and length of hospital stay after pancreaticoduodenectomy (Whipple's procedure)

Laurence Weinberg, Derrick Wong, Dharshi Karalapillai, Brett Pearce, Chong O Tan, Stanley Tay, Chris Christophi, Larry McNicol, Mehrdad Nikfarjam

Journal article  |  2014  |  BMC Anesthesiology

Glaucarubinone and gemcitabine synergistically reduce pancreatic cancer growth via down-regulation of P21-activated kinases

Dannel Yeo, Huynh Nhi, John A Beutler, Christopher Christophi, Arthur Shulkes, Graham S Baldwin, Mehrdad Nikfarjam, Hong He

Journal article  |  2014  |  Cancer Letters

P21-activated kinases as targets in pancreatic cancer

Hong He, Mehrdad Nikfarjam, Dannel Yeo, Xiao Wang, Nhi Huynh, Graham S Baldwin

Journal article  |  2014  |  Pancreatology

Pressurized Pulse Irrigation with Saline Reduces Surgical-site Infections following Major Hepatobiliary and Pancreatic Surgery: Randomized Controlled Trial

Mehrdad Nikfarjam, Laurence Weinberg, Michael A Fink, Vijayaragavan Muralidharan, Graham Starkey, Robert Jones, Kevin Staveley-O'Carroll, Christopher Christophi

Journal article  |  2014  |  World Journal of Surgery

Lymphatics and colorectal liver metastases: the case for sentinel node mapping

Christopher Christophi, Nguyen Linh, Vijayaragavan Muralidharan, Mehrdad Nikfarjam, Jonathan Banting

Journal article  |  2014  |  HPB: the official journal of the IHPBA

Groove pancreatitis, an illustration of two cases

Celia S-L Kuo, Kerryn F Ireland-Jenkin, Mehrdad Nikfarjam, David Williams

Journal article  |  2014  |  Pathology

Comparison of Two Syngeneic Orthotopic Murine Models of Pancreatic Adenocarcinoma

Mehrdad Nikfarjam, Dannel Yeo, Hong He, Graham Baldwin, Theodora Fifis, Patricia Costa, Bryan Tan, Eunice Yang, Shu Wen Wen, Christopher Christophi

Journal article  |  2013  |  Journal of Investigative Surgery

Improving outcomes for pancreatic cancer: radical surgery with patient-tailored, surgery-specific advanced haemodynamic monitoring.

L Weinberg, N Houli, M Nikfarjam

Journal article  |  2013  |  BMJ case reports

Percutaneous Cholecystostomy for Treatment of Acute Cholecystitis in the Era of Early Laparoscopic Cholecystectomy

Mehrdad Nikfarjam, Lilly Shen, Michael A Fink, Vijayaragavan Muralidharan, Graham Starkey, Robert M Jones, Christopher Christophi

Journal article  |  2013  |  Surgical Laparoscopy, Endoscopy and Percutaneous Techniques

Post-procedural considerations

AK Hadj, M Nikfarjam

Book Chapter  |  2013

Treatment with the vascular disruptive agent OXi4503 induces an immediate and widespread epithelial to mesenchymal transition in the surviving tumor

Theodora Fifis, Linh Nguyen, Cathy Malcontenti-Wilson, Lie Sam Chan, Patricia Luiza Nunes Costa, Jurstine Daruwalla, Mehrdad Nikfarjam, Vijayaragavan Muralidharan, Mark Waltham, Erik W Thompson, Christopher Christophi

Journal article  |  2013  |  Cancer Medicine

The utility of upfront double wire guided biliary cannulation following early unintentional pancreatic cannulation in patients undergoing ERCP.

Sujievvan Chandran, Mehrdad Nikfarjam

Journal article  |  2013  |  Indian Journal of Gastroenterology

This study aims to assess the impact of upfront double-guidewire technique (DGT) following inadvertent early pancreatic duct (PD) ..

Improving outcomes for pancreatic cancer: radical surgery with patient-tailored, surgery-specific advanced haemodynamic monitoring.

Laurence Weinberg, Nezor Houli, Mehrdad Nikfarjam

Journal article  |  2013  |  BMJ Case Reports

Pancreatic cancer has poor prognoses, with a median survival after diagnosis of less than 6 months. For some patients radical surg..

Biliary stenting versus surgical bypass for palliation of periampullary malignancy.

Mehrdad Nikfarjam, Andrew K Hadj, Vijayaragavan Muralidharan, Niall Tebbutt, Michael A Fink, Robert M Jones, Graham Starkey, Rhys B Vaughan, Alexander W Marshall, Christopher Christophi

Journal article  |  2013  |  Indian Journal of Gastroenterology

BACKGROUND: Patients with periampullary cancers may not be suitable for curative resection due to locally advanced disease, metast..

The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma (vol 486, pg 266, 2012)

Pedro A Perez-Mancera, Alistair G Rust, Louise van der Weyden, Glen Kristiansen, Allen Li, Aaron L Sarver, Kevin AT Silverstein, Robert Gruetzmann, Daniela Aust, Petra Ruemmele, Thomas Knoesel, Colin Herd, Derek L Stemple, Ross Kettleborough, Jacqueline A Brosnan, Ang Li, Richard Morgan, Spencer Knight, Jun Yu, Shane Stegeman, et al.

Journal article  |  2013  |  Nature

Sex Differences and Outcomes of Management of Acute Cholecystitis

Mehrdad Nikfarjam, Efrant Harnaen, Farrukh Tufail, Vijayaragavan Muralidharan, Michael A Fink, Graham Starkey, Robert M Jones, Christopher Christophi

Journal article  |  2013  |  Surgical Laparoscopy, Endoscopy and Percutaneous Techniques

A fast track recovery program significantly reduces hospital length of stay following uncomplicated pancreaticoduodenectomy.

Mehrdad Nikfarjam, Laurence Weinberg, Nicholas Low, Michael A Fink, Vijayaragavan Muralidharan, Nezor Houli, Graham Starkey, Robert Jones, Christopher Christophi

Journal article  |  2013  |  Journal of the Pancreas

CONTEXT: Factors affecting length of hospital stay after uncomplicated pancreaticoduodenectomy have not been reported. We hypothes..

Future of notes

Mehrdad Nikfarjam, Jeffrey Marks

Book Chapter  |  2013

Endoluminal treatments for gastroesophageal reflux disease

Mehrdad Nikfarjam, Jeffrey Ponsky

Book Chapter  |  2013

Outcomes of patients with histologically proven acute acalculous cholecystitis

Mehrdad Nikfarjam, Kiran Manya, Michael A Fink, Andrew K Hadj, Vijayaragavan Muralidharan, Graham Starkey, Robert M Jones, Christopher Christophi

Journal article  |  2012  |  ANZ Journal of Surgery

Spatial morphological and molecular differences within solid tumors may contribute to the failure of vascular disruptive agent treatments

Nguyen Linh, Theodora Fifis, Caterina Malcontenti-Wilson, Lie Sam Chan, Patricia Luiza Nunes Costa, Mehrdad Nikfarjam, Vijayaragavan Muralidharan, Christopher Christophi

Journal article  |  2012  |  BMC Cancer

Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes

Andrew V Biankin, Nicola Waddell, Karin S Kassahn, Marie-Claude Gingras, Lakshmi B Muthuswamy, Amber L Johns, David K Miller, Peter J Wilson, Ann-Marie Patch, Jianmin Wu, David K Chang, Mark J Cowley, Brooke B Gardiner, Sarah Song, Ivon Harliwong, Senel Idrisoglu, Craig Nourse, Ehsan Nourbakhsh, Suzanne Manning, Shivangi Wani, et al.

Journal article  |  2012  |  Nature

The utility of upfront double wire guided biliary cannulation technique following early unintentional pancreatic wire cannulation in patients undergoing endoscopic retrograde cholangiopancreatography

Sujievvan Chandran, Mehrdad Nikfarjam

Conference Proceedings  |  2012  |  JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Reduction in delayed gastric emptying following non-pylorus preserving pancreaticoduodenectomy by addition of a Braun enteroenterostomy.

Mehrdad Nikfarjam, Nezor Houli, Farrukh Tufail, Laurence Weinberg, Vijayaragavan Muralidharan, Christopher Christophi

Journal article  |  2012  |  Journal of the Pancreas

CONTEXT: Delayed gastric emptying is a major cause of morbidity following pancreaticoduodenectomy. OBJECTIVE: The impact of a Brau..

RON is not a prognostic marker for resectable pancreatic cancer

Carole M Tactacan, David K Chang, Mark J Cowley, Emily S Humphrey, Jianmin Wu, Anthony J Gill, Angela Chou, Katia Nones, Sean M Grimmond, Robert L Sutherland, Andrew V Biankin, Roger J Daly

Journal article  |  2012  |  BMC Cancer

The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma

Pedro A Perez-Mancera, Alistair G Rust, Louise van der Weyden, Glen Kristiansen, Allen Li, Aaron L Sarver, Kevin AT Silverstein, Robert Gruetzmann, Daniela Aust, Petra Ruemmele, Thomas Knoesel, Colin Herd, Derek L Stemple, Ross Kettleborough, Jacqueline A Brosnan, Ang Li, Richard Morgan, Spencer Knight, Jun Yu, Shane Stegeman, et al.

Journal article  |  2012  |  Nature

Cystic duct clip migration into the common bile duct.

David Rowe, Mehrdad Nikfarjam

Journal article  |  2012  |  Indian Journal of Gastroenterology

Lymphatic Patterns of Colorectal Liver Metastases

Andrew K Hadj, Cathy Malcontenti-Wilson, Mehrdad Nikfarjam, Christopher Christophi

Journal article  |  2012  |  Journal of Surgical Research

Gastrointestinal: Duodenal tumour and cutaneous skin lesions

M Nikfarjam, C Frias-Kletecka, J Hardacre

Journal article  |  2012  |  Journal of Gastroenterology and Hepatology

Spatial morphological and molecular differences within solid tumours may contribute to the failure of vascular disruptive agent treatments

L Nguyen, T Fifis, C Malcontenti-Wilson, undefined Chan, PL Costa, M Nikfarjam, V Muralidharan, C Christophi

Journal article  |  2012  |  BMC Cancer

Embryonal sarcoma of the liver in an adult patient.

Nicole Lightfoot, Mehrdad Nikfarjam

Journal article  |  2012  |  Case Reports in Surgery

Undifferentiated embryonal sarcomas (UESs) are uncommon tumours that are seen predominantly in late childhood. Cases in adults are..

Pseudoaneurysm of the Hepatic Artery

Andrew K Hadj, Mark Goodwin, Heinrich Schwalb, Mehrdad Nikfarjam

Journal article  |  2011  |  Journal of Gastrointestinal Surgery

Author index.

Journal article  |  2011  |  HPB

Outcomes of contemporary management of gangrenous and non-gangrenous acute cholecystitis

Mehrdad Nikfarjam, Vachara Niumsawatt, Arun Sethu, Michael A Fink, Vijayaragavan Muralidharan, Graham Starkey, Robert M Jones, Christopher Christophi

Journal article  |  2011  |  HPB: the official journal of the IHPBA

Direct diaphragm pacing stimulation

Mehrdad Nikfarjam, David A Story, Andrew Nunn, Mark Howard

Journal article  |  2011  |  ANZ Journal of Surgery

Induction of Th1Immune responses following laser ablation in a murine model of colorectal liver metastases

Wen Xu Lin, Theodora Fifis, Caterina Malcontenti-Wilson, Mehrdad Nikfarjam, Vijayaragavan Muralidharan, Nguyen Linh, Christopher Christophi

Journal article  |  2011  |  Journal of Translational Medicine

Paraganglioma mimicking a pancreatic neoplasm.

Nicole Lightfoot, Peter Santos, Mehrdad Nikfarjam

Journal article  |  2011  |  Journal of the Pancreas

CONTEXT: Paragangliomas are rare tumours of neural crest origin. Extra-adrenal pancreatic paragangliomas are exceptionally rare. C..

Changes in growth factor levels after thermal ablation in a murine model of colorectal liver metastases

Theodora Fifis, Caterina Malcontenti-Wilson, Jason Amijoyo, Beatrice Anggono, Vijayaragavan Muralidharan, Mehrdad Nikfarjam, Christopher Christophi

Journal article  |  2011  |  HPB: the official journal of the IHPBA

Concurrent lymphoma and pancreatic adenocarcinoma.

Jiun Miin Lai, Peter Crowley, Mehrdad Nikfarjam

Journal article  |  2011  |  Journal of the Pancreas

CONTEXT: Retroperitoneal lymph node enlargement in patients with pancreatic cancer is sometimes treated as incurable disease. Non-..

The Effect of Surgical Volume and the Provision of Residency and Fellowship Training on Complications of Major Hepatic Resection

Geoffrey Paul Kohn, Mehrdad Nikfarjam

Journal article  |  2010  |  Journal of Gastrointestinal Surgery

The diagnostic efficacy of natural orifice transluminal endoscopic surgery: is there a role in the intensive care unit?

Joseph A Trunzo, Benjamin K Poulose, Michael F McGee, Mehrdad Nikfarjam, Steve J Schomisch, Raymond P Onders, Judy Jin, Amitabh Chak, Jeffrey L Ponsky, Jeffrey M Marks

Journal article  |  2010  |  Surgical Endoscopy

In vitro and in vivo evaluation of tumor targeting styrene-maleic acid copolymer-pirarubicin micelles: Survival improvement and inhibition of liver metastases

Jurstine Daruwalla, Mehrdad Nikfarjam, Khaled Greish, Cathy Malcontenti-Wilson, Vijayaragavan Muralidharan, Chris Christophi, Hiroshi Maeda

Journal article  |  2010  |  Cancer Science

Transgastric natural-orifice transluminal endoscopic surgery peritoneoscopy in humans: a pilot study in efficacy and gastrotomy site selection by using a hybrid technique

Mehrdad Nikfarjam, Michael F McGee, Joseph A Trunzo, Raymond P Onders, Jonathan P Pearl, Benjamin K Poulose, Amitabh Chak, Jeffrey L Ponsky, Jeffrey M Marks

Journal article  |  2010  |  Gastrointestinal Endoscopy

Peritoneal inflammatory response of natural orifice translumenal endoscopic surgery (NOTES) versus laparoscopy with carbon dioxide and air pneumoperitoneum

Joseph A Trunzo, Michael F McGee, Leandro T Cavazzola, Steve Schomisch, Mehrdad Nikfarjam, Jessica Bailey, Tripurari Mishra, Benjamin K Poulose, Young-Joon Lee, Jeffrey L Ponsky, Jeffrey M Marks

Journal article  |  2010  |  Surgical Endoscopy

Anaesthetic aspects of implanting diaphragmatic pacing in patients with spinal cord injury

D Story, E Mariampillai, M Nikfarjam, M Howard, A Nunn, R Onders

Journal article  |  2010  |  Anaesthesia and Intensive Care

Feasibility of Radiofrequency Ablation for the Treatment of Chronic Radiation Proctitis

Mehrdad Nikfarjam, Ashley Faulx, Michelle Laughinghouse, Jeffrey M Marks

Journal article  |  2010  |  Surgical Innovation

Complete surgical resection of giant mucinous hepatic cystadenomas.

Mehrdad Nikfarjam, Eric T Kimchi, Niraj J Gusani, Kevin F Staveley-O'Carroll

Journal article  |  2010  |  American Surgeon

Duct of Luschka

M Nikfarjam, RP Onders, JM Marks

Journal article  |  2010  |  Asian Journal of Endoscopic Surgery

Pylorus preserving pancreaticoduodenectomy.

Mehrdad Nikfarjam

Journal article  |  2010  |  Saudi Journal of Gastroenterology

Author index.

Journal article  |  2010  |  HPB

ACS Multimedia Atlas of Surgery: Pancreas Surgery Volume

Mehrdad Nikfarjam, Jeffrey Ponsky

Book Chapter  |  2010

Human acellular dermal matrix: an innovative tool for diaphragmatic reconstruction in patients with large intra-abdominal tumors.

Diego Avella, Luis J Garcia, Niraj J Gusani, Mehrdad Nikfarjam, Serene Shereef, Eric T Kimchi, Kevin F Staveley-O'Carroll

Journal article  |  2010  |  American Journal of Surgery

BACKGROUND: Patients presenting with large intra-abdominal tumors often require multivisceral organ resection including partial or..

Combined pancreaticoduodenectomy and extended right hemicolectomy: outcomes and indications

Eric T Kimchi, Mehrdad Nikfarjam, Niraj J Gusani, Diego M Avella, Kevin F Staveley-O'Carroll

Journal article  |  2009  |  HPB: the official journal of the IHPBA

A Reduction in Delayed Gastric Emptying by Classic Pancreaticoduodenectomy with an Antecolic Gastrojejunal Anastomosis and a Retrogastric Omental Patch

Mehrdad Nikfarjam, Eric T Kimchi, Niraj J Gusani, Syed M Shah, Mandeep Sehmbey, Serene Shereef, Kevin F Staveley-O'Carroll

Journal article  |  2009  |  Journal of Gastrointestinal Surgery

Reduction of surgical site infections by use of pulsatile lavage irrigation after prolonged intra-abdominal surgical procedures

Mehrdad Nikfarjam, Eric T Kimchi, Niraj J Gusani, Diego M Avella, Serene Shereef, Kevin F Staveley-O'Carroll

Journal article  |  2009  |  American Journal of Surgery

Acute Management of Stoma-Related Colocutaneous Fistula by Temporary Placement of a Self-Expanding Plastic Stent

Mehrdad Nikfarjam, Brad Champagne, Harry L Reynolds, Benjamin K Poulose, Jeffrey L Ponsky, Jeffrey M Marks

Journal article  |  2009  |  Surgical Innovation

Survival Outcomes of Patients with Colorectal Liver Metastases Following Hepatic Resection or Ablation in the Era of Effective Chemotherapy

Mehrdad Nikfarjam, Serene Shereef, Eric T Kimchi, Niraj J Gusani, Yixing Jiang, Diego M Avella, Rickhesvar P Mahraj, Kevin F Staveley-O'Carroll

Journal article  |  2009  |  Annals of Surgical Oncology

Additional Organ Resection Combined with Pancreaticoduodenectomy does not Increase Postoperative Morbidity and Mortality

Mehrdad Nikfarjam, Mandeep Sehmbey, Eric T Kimchi, Niraj J Gusani, Serene Shereef, Diego M Avella, Kevin F Staveley-O'Carroll

Journal article  |  2009  |  Journal of Gastrointestinal Surgery

Completion Pancreatectomy for Treatment of a Clostridium perfringens Pancreatic Infection

Jovenel Cherenfant, Mehrdad Nikfarjam, Abraham Mathew, Eric T Kimchi, Kevin F Staveley-O'Carroll

Journal article  |  2009  |  Archives of Surgery

Pancreaticoduodenectomy in patients with a history of Roux-en Y gastric bypass surgery.

Mehrdad Nikfarjam, Kevin F Staveley-O'Carroll, Eric T Kimchi, Jeffrey M Hardacre

Journal article  |  2009  |  Journal of the Pancreas

CONTEXT: Roux-en Y gastric bypass surgery is the most common operation for treatment of morbid obesity. The approach to pancreatic..

Diagnosis and management of retroperitoneal ancient schwannomas

Haroon A Choudry, Mehrdad Nikfarjam, John J Liang, Eric T Kimchi, Robert Conter, Niraj J Gusani, Kevin F Staveley-O'Carroll

Journal article  |  2009  |  World Journal of Surgical Oncology

Early management of traumatic pancreatic transection by spleen-preserving laparoscopic distal pancreatectomy

Mehrdad Nikfarjam, Michael Rosen, Todd Ponsky

Journal article  |  2009  |  Journal of Pediatric Surgery

REDUCED DELAYED GASTRIC EMPTYING WITH CLASSIC PANCREATICODUODENECTOMY AND ANTECOLIC GASTROJEJUNAL ANASTOMOSIS

N Gusani, E Kimchi, M Nikfarjam, D Avella, K Staveley-O Carroll

Journal article  |  2008  |  Pancreas

COMBINED PANCREATICODUODENECTOMY AND RIGHT HEMICOLECTOMY - OUTCOMES AND INDICATIONS

E Kimchi, M Nikfarjam, N Gusani, D Avella, K Staveley-O Carroll

Journal article  |  2008  |  Pancreas

Surgical Outcomes of Patients with Gastrointestinal Stromal Tumors in the Era of Targeted Drug Therapy

Mehrdad Nikfarjam, Eric Kimchi, Serene Shereef, Niraj J Gusani, Yixing Jiang, John Liang, Mandeep Sehmbey, Kevin F Staveley-O'Carroll

Journal article  |  2008  |  Journal of Gastrointestinal Surgery

Optimizing imatinib mesylate treatment in gastrointestinal stromal tumors.

Yixing Jiang, Lee Ming, Alberto J Montero, Eric Kimchi, Mehrdad Nikfarjam, Kevin F Staveley-O'Carroll

Journal article  |  2008  |  Gastrointestinal Cancer Research

Improvements in the understanding of molecular oncogenesis and mechanisms of drug resistance have presented new opportunities for ..

Combined right nephrectomy and pancreaticoduodenectomy. Indications and outcomes.

Mehrdad Nikfarjam, Niraj J Gusani, Eric T Kimchi, Rickhesvar P Mahraj, Kevin F Staveley-O'Carroll

Journal article  |  2008  |  Journal of the Pancreas

CONTEXT: Nephrectomy and pancreaticoduodenctomy are operations often performed for the treatment of malignancy. However, the combi..

Vascular targeting agent Oxi4503 inhibits tumor growth in a colorectal liver metastases model

Caterina Malcontenti-Wilson, Lisa Chan, Mehrdad Nikfarjam, Vijayaragavan Muralidharan, Christopher Christophi

Journal article  |  2008  |  Journal of Gastroenterology and Hepatology

Education and imaging - Hepatobiliary and pancreatic: Isolated pancreatic metastases

M Nikfarjam, KF Staveley-O'Carroll, NJ Gusani, E Kimchi

Journal article  |  2008  |  Journal of gastroenterology and hepatology

Ischaemic colitis associated with colonic carcinoma

Sheng-Rong Low, Neil Strugnell, Mehrdad Nikfarjam

Journal article  |  2008  |  ANZ Journal of Surgery

Colorectal metastases to the pancreas.

Mehrdad Nikfarjam

Journal article  |  2008  |  jounral of gastroenterology and hepatology

Hepatobiliary and pancreatic: Isolated pancreatic metastases

M Nikfarjam, KF Staveley-O'Carroll, NJ Gusani, E Kimchi

Journal article  |  2008  |  Journal of Gastroenterology and Hepatology

Combine right nephrectomy and pancreaticoduodenectomy.  Indications and outcomes

M Nikfarjam, undefined Gusani, undefined Kimchi, undefined Mahraj, undefined Staveley-O'Carroll

Journal article  |  2008  |  Journal of the Pancreas

The Effect of laser induced thermal ablation on liver tumors.

Mehrdad Nikfarjam

Book  |  2008

Improved contemporary surgical management of insulinomas - A 25-year experience at the Massachusetts General Hospital

Mehrdad Nikfarjam, Andrew L Warshaw, Lloyd Axelrod, Vikram Deshpande, Sarah P Thayer, Cristina R Ferrone, Carlos Fernandez-del Castillo

Journal article  |  2008  |  Annals of Surgery

Hyperbaric oxygen therapy for severe acute pancreatitis

Christopher Christophi, Ian Millar, Mehrdad Nikfarjam, Vijayaragavan Muralidharan, Caterina Malcontenti-Wilson

Journal article  |  2007  |  Journal of Gastroenterology and Hepatology

Hyperbaric oxygen therapy reduces severity and improves survival in severe acute pancreatitis

Mehrdad Nikfarjam, Christine M Cuthbertson, Caterina Malcontenti-Wilson, Vijayaragavan Muralidharan, Ian Millar, Christopher Christophi

Journal article  |  2007  |  Journal of Gastrointestinal Surgery

Liver regeneration stimulates tumor metastases

Nadia Harun, Mehrdad Nikfarjam, Vijayaragavan Muralidharan, Christopher Christophi

Journal article  |  2007  |  Journal of Surgical Research

Evaluation of the effect of SMA-pirarubicin micelles on colorectal cancer liver metastases and of hyperbaric oxygen in CBA mice

Jurstine Daruwalla, Khaled Greish, Mehrdad Nikfarjam, Ian Millar, Cathy Malcontenti-Wilson, Arun K Iyer, Chris Christophi

Journal article  |  2007  |  Journal of Drug Targeting

Re: "Altered growth patterns of colorectal liver metastases after thermal ablation" - Response

Mehrdad Nikfarjam, Christopher Christophi

Journal article  |  2006  |  Surgery

SMA-pirarubicin inhibits growth of colorectal cancer liver metastases in an animal model

Jurstine Daruwalla, Khaled Greish, Mehrdad Nikfarjam, Cathy Malcontenti-Wilson, Hiroshi Maeda, Chris Christophi

Conference Proceedings  |  2006  |  CANCER RESEARCH

Impact of blood flow occlusion on liver necrosis following thermal ablation

M Nikfarjam, V Muralidharan, C Malcontenti-Wilson, W McLaren, C Christophi

Journal article  |  2006  |  ANZ Journal of Surgery

Altered growth patterns of colorectal liver metastases after thermal ablation

M Nikfarjam, V Muralidharan, C Christophi

Journal article  |  2006  |  Surgery

Retroperitoneal lymphangioma

Martin Cherk, Mehrdad Nikfarjam, Christopher Christophi

Journal article  |  2006  |  Asian Journal of Surgery

Effect of thalidomide on colorectal cancer liver metastases in CBA mice

J Daruwalla, M Nikfarjam

Journal article  |  2005  |  Journal of Surgical Oncology

Mechanisms of focal heat destruction of liver tumors

M Nikfarjam, V Muralidharan, C Christophi

Journal article  |  2005  |  Journal of Surgical Research

The management of liver tumours by percutaneous interstitial laser thermotherapy

M Nikfarjam, C Christophi

Journal article  |  2005  |  Emirates Medical Journal

Progressive microvascular injury in liver and colorectal liver metastases following laser induced focal hyperthermia therapy

M Nikfarjam, V Muralidharan, C Malcontenti-Wilson, C Christophi

Journal article  |  2005  |  Lasers in Surgery and Medicine

Comparison of 980-and 1064-nm wavelengths for interstitial laser thermotherapy of the liver

M Nikfarjam, C Malcontenti-Wilson, C Christophi

Journal article  |  2005  |  Photomedicine and Laser Surgery

Patterns of heat shock protein (HSP70) expression and Kupffer cell activity following thermal ablation of liver and colorectal liver metastases

M Nikfarjam, V Muralidharan, K Su, C Malcontenti-Wilson, C Christophi

Journal article  |  2005  |  International Journal of Hyperthermia

Focal hyperthermia produces progressive tumor necrosis independent of the initial thermal effects

M Nikfarjam, C Malcontenti-Wilson, C Christophi

Journal article  |  2005  |  Journal of Gastrointestinal Surgery

The apoptotic response of liver and colorectal liver metastases to focal hyperthermic injury

M Nikfarjam, V Muralidharan, C Malcontenti-Wilson, C Christophi

Journal article  |  2005  |  Anticancer Research

The apoptotic response of liver and colorectal liver metastases to focal hyperthermic injury

M Nikfarjam, V Muralidharan, C Malcontenti-Wilson, C Christophi

Journal article  |  2005  |  Anticancer Research

Selective endoscopic cholangiography for the detection of common bile duct stones in patients with cholelithiasis

D Katz, M Nikfarjam, A Sfakiotaki, C Christophi

Journal article  |  2004  |  Endoscopy

Long-term survival of patients with unresectable colorectal liver metastases treated by percutaneous interstitial laser thermotherapy

C Christophi, M Nikfarjam, C Malcontenti-Wilson, V Muralidharan

Journal article  |  2004  |  World Journal of Surgery

Mechanisms of liver tumor ablation by focal hyperthermia

M Nikfarjam, V Muralidharan, C Malcontenti-Wilson, C Christophi

Conference Proceedings  |  2004  |  HEPATOLOGY

Improved survival following interstitial laser thermotherapy for the treatment of unresectable colorectal liver metastases

M Nikfarjam, V Muralidharan, C Christophi

Conference Proceedings  |  2004  |  HEPATOLOGY

Long-term Survival of Patients with Unresectable Colorectal Liver Metastases treated by Percutaneous Interstitial Laser Thermotherapy

Christopher Christophi, Mehrdad Nikfarjam, Caterina Malcontenti-Wilson, Vijayaragavan Muralidharan

Journal article  |  2004  |  World Journal of Surgery

A model of partial hepatectomy in mice

M Nikfarjam, C Malcontenti-Wilson, M Fanartzis, J Daruwalla, C Christophi

Journal article  |  2004  |  Journal of Investigative Surgery

Not all hepatic carcinoids are metastases

M Nikfarjam, P Evans, V Muralidharan, C Christophi

Journal article  |  2004  |  Journal of Gastroenterology and Hepatology

Primary hepatic carcinoid tumours.

M Nikfarjam, V Muralidharan, C Christophi

Journal article  |  2004  |  HPB: the official journal of the IHPBA

BACKGROUND: Carcinoid tumours of the liver are predominantly metastases from the gastrointestinal tract. Primary hepatic carcinoid..

Effect of interstitial laser hyperthermia in a murine model of colorectal liver metastases: Scanning electron microscopic study

V Muralidharan, M Nikfarjam, C Malcontenti-Wilson, C Christophi

Journal article  |  2004  |  World Journal of Surgery

Scanning electron microscopy study of the blood supply of human colorectal liver metastases

M Nikfarjam, V Muralidharan, C Malcontenti-Wilson, C Christophi

Journal article  |  2003  |  European Journal of Surgical Oncology

Small bowel diverticular disease complicated by perforation

S Nightingale, M Nikfarjam, L Iles, M Djeric

Journal article  |  2003  |  ANZ Journal of Surgery

Interstitial laser thermotherapy for liver tumours

M Nikfarjam, C Christophi

Journal article  |  2003  |  British Journal of Surgery

Internal hernia tranversing the lesser sac

M Nikfarjam, C Christophi

Journal article  |  2003  |  College of Surgeons Hong Kong - Annals

Interstitial laser hyperthermia and the biological characteristics of tumor: Study in a murine model of colorectal liver metastases

V Muralidharan, M Nikfarjam, C Malcontenti-Wilson, C Christophi

Journal article  |  2003  |  Journal of Clinical Laser Medicine and Surgery

Primary bile duct carcinoma in histocompatibility antigen-identical twins

C Christophi, M Nikfarjam, V Muralidharan, F Dudley

Journal article  |  2003  |  Journal of Gastroenterology and Hepatology

Pancreatic resection for metastatic melanoma.

M Nikfarjam, P Evans, C Christophi

Journal article  |  2003  |  HPB: the official journal of the IHPBA

BACKGROUND: The pancreas is an occasional site of metastases from melanoma. It may be the only location of metastatic disease, but..

Neuroendocrine tumours of the ampulla of vater

M Nikfarjam, C McLean, V Muralidharan, C Christophi

Journal article  |  2002  |  ANZ Journal of Surgery

Autoimmune pancreatitis

M Nikfarjam, V Muralidharan, C Christophi, H Tang, D Clouston

Journal article  |  2002  |  ANZ Journal of Surgery

Local resection of ampullary adenocarcinomas of the duodenum

M Nikfarjam, V Muralidharan, C McLean, C Christophi

Journal article  |  2001  |  ANZ Journal of Surgery