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FEATURED Journal article
Whole genomes redefine the mutational landscape of pancreatic cancerRead more
Mehrdad Nikfarjam's selected work
IMPROVING THE TREATMENT OF PANCREATIC CANCER BY NOVEL TREATMENT TARGETS
A ray of hope for pancreatic cancer
Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes
The role of P21 activated kinase 4 (PAK4) in pancreatic cancer tumorigenesis
The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma
Reprogramming the tumour microenvironment of pancreatic cancer to improve response to ther..
Mehrdad Nikfarjam's selected work
Displaying the 10 most recent projects from 12 for Mehrdad Nikfarjam.
Internal Research Grant
Displaying the 10 most recent scholarly works from 242 for Mehrdad Nikfarjam.
Prospective multicentre randomised controlled trial of the effect of Braun Enteroenterostomy in the Reconstruction after Pancreaticoduodenectomy on delayed gastric emptying (DGE): protocol for the BERP study.
Saksham Gupta, Kai Brown, Natalie Lott, Rosemary Carroll, David Burnett, Mehrdad Nikfarjam
Journal article | 2022 | BMJ Open
INTRODUCTION: Despite advances in achieving low mortality rates with pancreaticoduodenectomy (PD), morbidity remains high. A key c..
The trilogy of P21 activated kinase, autophagy and immune evasion in pancreatic ductal adenocarcinoma.
Yi Ma, Mehrdad Nikfarjam, Hong He
Journal article | 2022 | Cancer Lett
Pancreatic Ductal Adenocarcinoma (PDA) is one of the most lethal types of cancer with a dismal prognosis. KRAS mutation is a commo..
Radiofrequency Ablation Versus Repeat Hepatectomy for Recurrent Hepatocellular Carcinoma: A Systematic Review and Meta-Analysis.
Marcus Yeow, Joseph J Zhao, Khi Yung Fong, Joel Wong, Alvin Yong Hui Tan, Juinn Huar Kam, Mehrdad Nikfarjam, Brian KP Goh, Tousif Kabir
Journal article | 2022 | World J Surg
BACKGROUND: An updated systematic review and meta-analysis was conducted to compare radiofrequency ablation (RFA) versus repeat he..
A mixed blessing for liver transplantation patients - Rapamycin.
Guang-Han Fan, Chen-Zhi Zhang, Feng-Qiang Gao, Xu-Yong Wei, Sun-Bin Ling, Kai Wang, Jian-Guo Wang, Shu-Sen Zheng, Mehrdad Nikfarjam, Xiao Xu
Journal article | 2022 | Hepatobiliary Pancreat Dis Int
BACKGROUND: Liver transplantation (LT) is an effective treatment option for end-stage liver disease. Mammalian target of rapamycin..
Inhibition of HCK in myeloid cells restricts pancreatic tumor growth and metastasis.
Ashleigh R Poh, Megan O'Brien, David Chisanga, Hong He, David Baloyan, Jasmin Traichel, Christine Dijkstra, Michaël Chopin, Stephen Nutt, Lachlan Whitehead, Louis Boon, Ashleigh Parkin, Clifford Lowell, Marina Pajic, Wei Shi, Mehrdad Nikfarjam, Matthias Ernst
Journal article | 2022 | Cell Rep
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive disease with a low 5-year survival rate and is associated with poor respo..
Impact of first-line FOLFIRINOX versus Gemcitabine/Nab-Paclitaxel chemotherapy on survival in advanced pancreatic cancer: Evidence from the prospective international multicentre PURPLE pancreatic cancer registry.
Jordan Santucci, Mark Tacey, Benjamin Thomson, Michael Michael, Rachel Wong, Julia Shapiro, Ross Jennens, Kate Clarke, Sharon Pattison, Matthew Burge, Rob Zielinski, Mehrdad Nikfarjam, Sumitra Ananda, Lara Lipton, Peter Gibbs, Belinda Lee
Journal article | 2022 | Eur J Cancer
BACKGROUND: First-line palliative chemotherapy regimens in advanced pancreatic ductal adenocarcinoma (PDAC) have not been compared..
1308P Comparison of tumour size on outcomes for patients with unresectable locally advanced pancreatic adenocarcinoma (LAPC) receiving P-32 microparticles with standard-of-care chemotherapy (SoC CT)
P Ross, HS Wasan, D Croagh, M Nikfarjam, N Nguyen, M Aghmesheh, A Nagrial, D Bartholomeusz, A Hendlisz, T Ajithkumar, C Iwuji, DM Turner, D James, M Harris
Journal article | 2022 | Annals of Oncology
Use and outcomes from neoadjuvant chemotherapy in borderline resectable pancreatic ductal adenocarcinoma in an Australasian population
Imogen Walpole, Belinda Lee, Jeremy Shapiro, Benjamin Thomson, Lara Lipton, Sumitra Ananda, Val Usatoff, Sue-Ann Mclachlan, Brett Knowles, Adrian Fox, Rachel Wong, Prasad Cooray, Matthew Burge, Kate Clarke, Sharon Pattison, Mehrdad Nikfarjam, Niall Tebbutt, Marion Harris, Adnan Nagrial, Rob Zielinski, et al.
Conference Proceedings | 2022 | ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY
Background: Use of neoadjuvant (NA) chemotherapy is recommended when pancreatic ductal adenocarcinoma (PDAC) is borderline resecta..
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Honours, Awards and Fellowships
Sir Edward Hughes Memorial Research Award
RC Bennett Research Medal
Austhos Travelling Research Fellowship
Surgery and Anaesthetic research prize
Surgeon Scientist Scholarship
DS Rosengarten Award
Prince Henry's Prize in Surgery
First Class Honours
FACS - Fellow of the American College of Surgeons
FRACS - Fellow of the Royal Australasian College of Surgeons
Surgery - Austin Health
American Society for Gastrointestinal Endoscopy
American Hepato Pancreatico-Biliary
Royal Australasian College of Surgeons
Pennsylvania State Board of Medicine
Doctorate of Philosophy
University of Melbourne
Fellow of the Royal Australasian College of Surgeons
The Royal Australasian College of Surgeons
Medical Bachelor and Bachelor of Surgery
Certificates & Licences
General Medical Council, UK
Awarded: 01 Jan 2005
ECFMG Registration, USA
Awarded: 01 Jan 2006
Case Western Reserve University
Pennsylvania State University