Stephen Harrap

The assertive cardiac care trial: A randomised controlled trial of a coproduced assertive cardiac care intervention to reduce absolute cardiovascular disease risk in people with severe mental illness in the primary care setting.

Matthew Lewis, Patty Chondros, Cathrine Mihalopoulos, Yong Yi Lee, Jane M Gunn, Carol Harvey, John Furler, David Osborn, David Castle, Sandra Davidson, Mahesh Jayaram, Amanda Kenny, Mark R Nelson, Vera A Morgan, Stephen Harrap, Kylie McKenzie, Maria Potiriadis, Konstancja Densley, Victoria J Palmer

Journal article  |  2020  |  Contemporary Clinical Trials

BACKGROUND: Cardiovascular disease (CVD) accounts for 40% of the excess mortality identified in people with severe mental illness ..

Alternative kidney filtration markers and the risk of major macrovascular and microvascular events, andall-causemortality in individuals with type 2 diabetes in theADVANCEtrial

Hyunju Kim, Dan Wang, John Chalmers, Min Jun, Sophia Zoungas, Michel Marre, Pavel Hamet, Stephen Harrap, Giuseppe Mancia, Neil R Poulter, Mark E Cooper, Mark Woodward, Elizabeth Selvin, Casey M Rebholz

Journal article  |  2020  |  Journal of Diabetes

BACKGROUND: Creatinine-based estimated glomerular filtration rate (eGFR) is biased in the setting of obesity and other conditions...

Sex-specific associations between cardiovascular risk factors and myocardial infarction in patients with type 2 diabetes: TheADVANCE-ONstudy

Toshiaki Ohkuma, Sanne AE Peters, Min Jun, Stephen Harrap, Mark Cooper, Pavel Hamet, Neil Poulter, John Chalmers, Mark Woodward

Journal article  |  2020  |  Diabetes, Obesity and Metabolism

AIM: To examine possible sex differences in the excess risk of myocardial infarction (MI) consequent to a range of conventional ri..

Effects of Intensive Glycemic Control on Clinical Outcomes Among Patients With Type 2 Diabetes With Different Levels of Cardiovascular Risk and Hemoglobin A(1c) in the ADVANCE Trial

Jingyan Tian, Toshiaki Ohkuma, Mark Cooper, Stephen Harrap, Giuseppe Mancia, Neil Poulter, Ji-Guang Wang, Sophia Zoungas, Mark Woodward, John Chalmers

Journal article  |  2020  |  Diabetes Care

OBJECTIVE: To study whether the effects of intensive glycemic control on major vascular outcomes (a composite of major macrovascul..

Plasma fatty acids and the risk of vascular disease and mortality outcomes in individuals with type 2 diabetes: results from the ADVANCE study

Katie Harris, Megumi Oshima, Naveed Sattar, Peter Wurtz, Min Jun, Paul Welsh, Pavel Hamet, Stephen Harrap, Neil Poulter, John Chalmers, Mark Woodward

Journal article  |  2020  |  Diabetologia

AIMS/HYPOTHESIS: This biomarker study aimed to quantify the association of essential and other plasma fatty acid biomarkers with m..

Self-rated health scores predict mortality among people with type 2 diabetes differently across three different country groupings: findings from the ADVANCE and ADVANCE-ON trials

X Hua, TWC Lung, M Woodward, JA Salomon, P Hamet, SB Harrap, G Mancia, N Poulter, J Chalmers, PM Clarke

Journal article  |  2020  |  Diabetic Medicine

AIMS: To explore whether there is a different strength of association between self-rated health and all-cause mortality in people ..

Does glyceryl trinitrate cause central sympatholytic effects? Insights from a case of baroreflex failure

Sarah Tan, Lin Xie, Robert Anderson, Andrew Hammond, Angelina Y Fong, Seok Lim, Andrew M Allen, Stephen B Harrap

Journal article  |  2020  |  Internal Medicine Journal

Whether part of the blood pressure lowering effects of glyceryl trinitrate (GTN) is the result of centrally mediated reduction in ..

The Risks of Cardiovascular Disease and Mortality Following Weight Change in Adults with Diabetes: Results from ADVANCE

Alexandra K Lee, Mark Woodward, Dan Wang, Toshiaki Ohkuma, Bethany Warren, A Richey Sharrett, Bryan Williams, Michel Marre, Pavel Hamet, Stephen Harrap, John W Mcevoy, John Chalmers, Elizabeth Selvin

Journal article  |  2020  |  The Journal of Clinical Endocrinology & Metabolism

CONTEXT: Weight loss is strongly recommended for overweight and obese adults with type 2 diabetes. Unintentional weight loss is as..

Change in Blood Pressure Variability Among Treated Elderly Hypertensive Patients and Its Association With Mortality.

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Journal article  |  2019  |  Journal of the American Heart Association

Background Information is scarce regarding effects of antihypertensive medication on blood pressure variability (BPV) and associat..

The relationship between eGFR slope and subsequent risk of vascular outcomes and all-cause mortality in type 2 diabetes: the ADVANCE-ON study

Megumi Oshima, Min Jun, Toshiaki Ohkuma, Tadashi Toyama, Takashi Wada, Mark E Cooper, Samy Hadjadj, Pavel Hamet, Stephen Harrap, Giuseppe Mancia, Michel Marre, Bryan Williams, John Chalmers, Mark Woodward, Vlado Perkovic

Journal article  |  2019  |  Diabetologia

AIMS/HYPOTHESIS: Some studies have reported that annual change in eGFR (eGFR slope) is associated with the future risk of end-stag..