Mark Hew

Comorbidities Modify the Phenotype but Not the Treatment Effectiveness to Mepolizumab in Severe Eosinophilic Asthma.

Vicky Kritikos, Erin S Harvey, Sean Stevens, Constance H Katelaris, David Langton, Janet Rimmer, Claude S Farah, Andrew Gillman, Mark Hew, Naghmeh Radhakrishna, Dennis Thomas, Peter G Gibson, undefined Australian Mepolizumab Registry Investigators

Journal article  |  2023  |  J Allergy Clin Immunol Pract

BACKGROUND: Comorbidities in severe asthma are common and contribute to disease burden. The severe asthma phenotype and treatment ..

Diagnostic value of a medical algorithm for investigation of perioperative hypersensitivity reactions.

Asger Sverrild, John Carruthers, Kavitha Garuna Murthee, Alice Moore, Robyn Elizabeth O'Hehir, Robert Puy, Mark Hew, Celia Zubrinich

Journal article  |  2023  |  Allergy

BACKGROUND: Evaluation of perioperative hypersensitivity (POH) is challenging, and accurate screening tools are needed to optimize..

Electronic Monitoring Devices to Support Inhalation Technique in Patients with Asthma: a Narrative Review

AA Eikholt, MBR Wiertz, M Hew, AHY Chan, JFM van Boven

Journal article  |  2023  |  Current Treatment Options in Allergy

Purpose of Review: Improper inhaling technique is common and is associated with poor patient outcomes. However, digital e-health d..

Advancing Digital Solutions to Overcome Longstanding Barriers in Asthma and COPD Management.

Sinthia Bosnic-Anticevich, Nawar Diar Bakerly, Henry Chrystyn, Mark Hew, Job van der Palen

Journal article  |  2023  |  Patient Prefer Adherence

Maintenance therapy delivered via inhaler is central to asthma and chronic obstructive pulmonary disease (COPD) management. Poor a..

Biomarkers of asthma relapse and lung function decline in adults with spontaneous asthma remission: A population-based cohort study

Daniel J Tan, Caroline J Lodge, Eugene Haydn Walters, Adrian J Lowe, Dinh S Bui, Gayan Bowatte, Rangi Kandane-Rathnayake, Fahad M Aldakheel, Bircan Erbas, Garun S Hamilton, Paul S Thomas, Mark Hew, Mimi LK Tang, Michael J Abramson, Jennifer L Perret, Shyamali C Dharmage

Conference Proceedings  |  2022  |  ALLERGY

BACKGROUND: The extent to which biomarkers of asthma activity persist in spontaneous asthma remission and whether such markers are..

RNA sequencing of single allergen-specific memory B cells after grass pollen immunotherapy: Two unique cell fates and CD29 as a biomarker for treatment effect

Craig McKenzie, Nirupama Varese, Pei Mun Aui, Simone Reinwald, Bruce D Wines, P Mark Hogarth, Francis Thien, Mark Hew, Jennifer M Rolland, Robyn E O'Hehir, Menno C van Zelm

Journal article  |  2022  |  ALLERGY

BACKGROUND: Sublingual immunotherapy (SLIT) for grass pollen allergy can modify the natural history of allergic rhinitis and is as..

Breathing pattern disorder

Eve Denton, Janet Bondarenko, Mark Hew

Book Chapter  |  2022

Laryngoscopy diagnosis of inducible laryngeal obstruction during supervised challenge for suspected anaphylaxis.

Stephanie Stojanovic, Celia Zubrinich, Asger Sverrild, Janine Mahoney, Eve Denton, Joy Lee, Mark Hew

Journal article  |  2022  |  Clin Exp Allergy

Regional variation in prevalence of difficult-to-treat asthma and oral corticosteroid use for patients in Australia: heat map analysis.

Peter AB Wark, Mark Hew, Yang Xu, Clare Ghisla, Tra-My Nguyen, Bora Erdemli, Aditya Samant, Cassandra Nan

Journal article  |  2022  |  J Asthma

BACKGROUND: In Australia, the regional prevalence of difficult-to-treat asthma is unknown. We aimed to describe regional variation..

Global Variability in Administrative Approval Prescription Criteria for Biologic Therapy in Severe Asthma.

Celeste M Porsbjerg, Andrew N Menzies-Gow, Trung N Tran, Ruth B Murray, Bindhu Unni, Shi Ling Audrey Ang, Marianna Alacqua, Mona Al-Ahmad, Riyad Al-Lehebi, Alan Altraja, Andrey S Belevskiy, Unnur S Björnsdóttir, Arnaud Bourdin, John Busby, G Walter Canonica, George C Christoff, Borja G Cosio, Richard W Costello, J Mark FitzGerald, João A Fonseca, et al.

Journal article  |  2022  |  J Allergy Clin Immunol Pract

BACKGROUND: Regulatory bodies have approved five biologics for severe asthma. However, regional differences in accessibility may l..