Frank Caruso

Programmable Phototaxis of Metal-Phenolic Particle Microswimmers.

Gan Lin, Joseph J Richardson, Heba Ahmed, Quinn A Besford, Andrew J Christofferson, Sebastian Beyer, Zhixing Lin, Amgad R Rezk, Marco Savioli, Jiajing Zhou, Chris F McConville, Christina Cortez-Jugo, Leslie Y Yeo, Frank Caruso

Journal article  |  2021  |  Advanced Materials

Light-driven directional motion is common in nature but remains a challenge for synthetic microparticles, particularly regarding c..

Protocols for Reproducible, Increased-Scale Synthesis of Engineered Particles—Bridging the “Upscaling Gap”

Steve Spoljaric, Yi Ju, Frank Caruso

Journal article  |  2021  |  Chemistry of Materials

In Vivo T Cell-Targeting Nanoparticle Drug Delivery Systems: Considerations for Rational Design.

Paula M Cevaal, Abdalla Ali, Ewa Czuba-Wojnilowicz, Jori Symons, Sharon R Lewin, Christina Cortez-Jugo, Frank Caruso

Journal article  |  2021  |  ACS Nano

T cells play an important role in immunity and repair and are implicated in diseases, including blood cancers, viral infections, a..

Microemulsion-Assisted Templating of Metal-Stabilized Poly(ethylene glycol) Nanoparticles.

Gan Lin, Christina Cortez-Jugo, Yi Ju, Quinn A Besford, Timothy M Ryan, Shuaijun Pan, Joseph J Richardson, Frank Caruso

Journal article  |  2021  |  Biomacromolecules

Poly(ethylene glycol) (PEG) is well known to endow nanoparticles (NPs) with low-fouling and stealth-like properties that can reduc..

Engineered Coatings via the Assembly of Amino-Quinone Networks

Qi-Zhi Zhong, Joseph J Richardson, Ai He, Tian Zheng, Rene PM Lafleur, Jianhua Li, Wen-Ze Qiu, Denzil Furtado, Shuaijun Pan, Zhi-Kang Xu, Ling-Shu Wan, Frank Caruso

Journal article  |  2020  |  Angewandte Chemie International Edition

Engineering coatings with precise physicochemical properties allows for control over the interface of a material and its interacti..

Person-Specific Biomolecular Coronas Modulate Nanoparticle Interactions with Immune Cells in Human Blood

Yi Ju, Hannah G Kelly, Laura F Dagley, Arnold Reynaldi, Timothy E Schlub, Sukhdeep K Spall, Craig A Bell, Jiwei Cui, Andrew J Mitchell, Zhixing Lin, Adam K Wheatley, Kristofer J Thurecht, Miles P Davenport, Andrew Webb, Frank Caruso, Stephen J Kent

Journal article  |  2020  |  ACS Nano

When nanoparticles interact with human blood, a multitude of plasma components adsorb onto the surface of the nanoparticles, formi..

Polyphenol-Based Nanoparticles for Intracellular Protein Delivery via Competing Supramolecular Interactions

Yiyuan Han, Jiajing Zhou, Yingjie Hu, Zhixing Lin, Yutian Ma, Joseph J Richardson, Frank Caruso

Journal article  |  2020  |  ACS Nano

Intracellular delivery of proteins is a promising strategy for regulating cellular behavior and therefore has attracted interest f..

RNAi therapeutics: an antiviral strategy for human infections

Anthony D Kelleher, Christina Cortez-Jugo, Francesca Cavalieri, Yijiao Qu, Allan R Glanville, Frank Caruso, Geoff Symonds, Chantelle L Ahlenstiel

Journal article  |  2020  |  Current Opinion in Pharmacology

Gene silencing induced by RNAi represents a promising antiviral development strategy. This review will summarise the current state..

Catalytically Active Copper Phosphate-Dextran Sulfate Microparticle Coatings for Bioanalyte Sensing

Pietro Pacchin Tomanin, Sukhvir Kaur Bhangu, Frank Caruso, Francesca Cavalieri

Journal article  |  2020  |  Particle and Particle Systems Characterization

Engineering reactive and functional nanostructured surfaces is important for enhancing the sensitivity and versatility of biosenso..

Particle engineering enabled by polyphenol-mediated supramolecular networks.

Jiajing Zhou, Zhixing Lin, Matthew Penna, Shuaijun Pan, Yi Ju, Shiyao Li, Yiyuan Han, Jingqu Chen, Gan Lin, Joseph J Richardson, Irene Yarovsky, Frank Caruso

Journal article  |  2020  |  Nature Communications

We report a facile strategy for engineering diverse particles based on the supramolecular assembly of natural polyphenols and a se..