Salvatore Pepe

Neonatal Subcutaneous BCG Vaccination Decreases Atherosclerotic Plaque Number and Plaque Macrophage Content in ApoE(-/-) Mice

Siroon Bekkering, Krishan Singh, Hui Lu, Albert P Limawan, Claudia A Nold-Petry, Megan J Wallace, Nigel Curtis, Salvatore Pepe, Michael Cheung, David P Burgner, Timothy Moss

Journal article  |  2022  |  BIOLOGY-BASEL

Bacille-Calmette Guérin (BCG) modulates atherosclerosis development in experimental animals, but it remains unclear whether neonat..

S-Nitrosoglutathione Limits Apoptosis and Reduces Pulmonary Vascular Dysfunction After Bypass.

Roberto Chiletti, Martin Bennett, Kelly Kenna, Julie Angerosa, Freya L Sheeran, Johann Brink, Stephanie Perrier, Diana Zannino, Joseph Smolich, Salvatore Pepe, Michael MH Cheung

Journal article  |  2022  |  Ann Thorac Surg

BACKGROUND: During hypoxia or acidosis, S-nitrosoglutathione (GSNO) has been shown to protect the cardiomyocyte from ischemia-repe..

Preserved Left Ventricular Function despite Myocardial Fibrosis and Myopathy in the Dystrophin-Deficient D2.B10-Dmd(mdx)/J Mouse

Holly M Hayes, Julie Angerosa, Adam T Piers, Jason D White, Jane Koleff, Madeline Thurgood, Jessica Moody, Michael M Cheung, Salvatore Pepe

Journal article  |  2022  |  OXIDATIVE MEDICINE AND CELLULAR LONGEVITY

Duchenne muscular dystrophy involves an absence of dystrophin, a cytoskeletal protein which supports cell structural integrity and..

Arterial Stiffness in Congenital Heart Disease

Kieran Sandhu, Salvatore Pepe, Joseph J Smolich, Michael MH Cheung, Jonathan P Mynard

Journal article  |  2021  |  HEART LUNG AND CIRCULATION

Transposition of the great arteries (TGA), coarctation of the aorta (CoA), single ventricle (SV) and tetralogy of Fallot (ToF) are..

Vascular Ageing: A Key Frontier in the Fight Against Cardiovascular Disease

Rachel E Climie, Ann T Gregory, A Robert Denniss, Jonathan P Mynard, Salvatore Pepe

Journal article  |  2021  |  HEART LUNG AND CIRCULATION

Myocarditis, Pericarditis and Cardiomyopathy After COVID-19 Vaccination

Salvatore Pepe, T Ann Gregory, A Robert Denniss

Journal article  |  2021  |  HEART LUNG AND CIRCULATION

Postnatal inflammation in ApoE-/- mice is associated with immune training and atherosclerosis

Ellesandra C Noye, Siroon Bekkering, Albert P Limawan, Maria U Nguyen, Lisa K Widiasmoko, Hui Lu, Salvatore Pepe, Michael M Cheung, Trevelyan R Menheniott, Megan J Wallace, Timothy J Moss, David P Burgner, Kirsty R Short

Journal article  |  2021  |  CLINICAL SCIENCE

BACKGROUND AND AIMS: Preterm birth is associated with increased risk of cardiovascular disease (CVD). This may reflect a legacy of..

A switch in mechanism of action attenuates doxorubicin-mediated cardiotoxicity.

Alison Cheong, Sean McGrath, Tina Robinson, Ruqaya Maliki, Alex Spurling, Ada Rephaeli, Abraham Nudelman, Don R Phillips, Belinda S Parker, Salvatore Pepe, Suzanne M Cutts

Conference Proceedings  |  2021  |  CANCER RESEARCH

Abstract 992: A switch in mechanism of action attenuates doxorubicin-mediated cardiotoxicity

Alison Cheong, Sean McGrath, Tina Robinson, Ruqaya Maliki, Alex Spurling, Ada Rephaeli, Abraham Nudelman, Don R Phillips, Belinda S Parker, Salvatore Pepe, Suzanne M Cutts

Conference Proceedings  |  2021  |  Cancer Research

Abstract Chemotherapy remains as the mainstay systemic therapy for triple negative breast cancer patients since tar..

A switch in mechanism of action prevents doxorubicin-mediated cardiac damage

Alison Cheong, Sean McGrath, Tina Robinson, Ruqaya Maliki, Alex Spurling, Peter Lock, Ada Rephaeli, Abraham Nudelman, Belinda S Parker, Salvatore Pepe, Suzanne M Cutts

Journal article  |  2021  |  BIOCHEMICAL PHARMACOLOGY

Cancer patients treated with doxorubicin are at risk of congestive heart failure due to doxorubicin-mediated cardiotoxicity via to..