Assoc/Prof. Salvatore Pepe is a clinical scientist who leads the Molecular & Cellular Cardiology Laboratory in the Heart Research Group (Clinical Sciences Theme) at the Murdoch Children's Research Institute (MCRI) and is a clinical research manager in the Department of Cardiology, Royal Children's Hospital.
After initially training in clinical pharmacology and completing a doctorate in cardiovascular physiology he undertook four years post-doctoral training (NIH Fogarty Postdoctoral Fellow) at Johns Hopkins Hospital, Bayview Campus, Baltimore, USA, in the NIH, National Institute on Aging Intramural Research Program (Cardiovascular Science).
Previous to working at Melbourne Children's Campus he was Head of the Cardiothoracic Surgical Research Laboratory, (Dept of Cardiothoracic Surgery), at the Alfred Hospital, and Adjunct Senior Lecturer, Department of Surgery (Alfred), Monash University, Melbourne, involved in clinical trial and laboratory research focused on cellular and mitochondrial processes in heart failure, transplantation, and cardiopulmonary bypass surgery.
Working with cardiac surgery, cardiology and intensive care clinicians, Dr Pepe's work is focused on cardiovascular complications arising from congenital and acquired heart and lung disorders, premature birth and surgical interventions.
The emphasis of the research effort is to translate new understanding of disease mechanisms and novel therapeutic agents to clinical use. Currently he is investigating the safety and efficacy of cord blood stem cell therapy as an adjunct to cardiopulmonary bypass surgery in children with severe heart malformations (i.e. hypoplastic left heart syndrome) or with cardiomyopathy. The research program over the past decade spans from in vitro and in vivo laboratory studies to clinical trials.
A/Prof Pepe has served NHMRC, NHF and ARC as a panel member and external reviewer, and is an invited reviewer for numerous medical and scientific journals. Currently he is an Associate Editor of Heart Lung and Circulation (Elsevier) and Clinical and Experimental Pharmacology and Physiology (Wiley), and also an editorial board member of the Journal of Molecular and Cellular Cardiology (Elsevier) and Heliyon (Elsevier). He is Past-President of the International Society for Heart Research and in 2016 was awarded the ISHR Distinguished Leader Award.
Find out more about Salvatore Pepe's experience
Salvatore Pepe's highlights
FEATURED Journal article
Remote ischaemic preconditioning modifies serum apolipoprotein D, met-enkephalin, adenosine, and nitric oxide in healthy young adults
Read moreSalvatore Pepe's selected work
Projects
Displaying the most recent project by Salvatore Pepe.
Scholarly Works
Displaying the 39 most recent scholarly works by Salvatore Pepe.
Keyword Analysis
Honours, Awards and Fellowships
International Society for Heart Research Distinguished Leader Award 2016
FCSANZ - Fellow of the Cardiac Society of Australia and New Zealand
FSGC - Fellow of the Society for Gerontological Cardiology
FAHA - Fellow of the American Heart Association
Credentials
Positions
Honorary
Paediatrics Royal Children'S Hospital
Membership Of The Perinatal Society Of Australia And New Zealand
Perinatal Society of Australia and New Zealand
American Physiological Society -Cardiovascular Section
American Physiological Society
Fellowship Of The Cardiac Society Of Australia And New Zealand
Cardiac Society of Australia and New Zealand
Fellowship Of American Heart Association
American Heart Association
International Society For Heart Research -Australasian Section
International Society for Heart Research
Education
BScHonsMed
Flinders University of South Australia
GDipHealth Counselling
University of South Australia
Doctor of Philosophy
Adelaide University