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Dr

Barbara Fam White

Senior Research Fellow - Proietto
Medicine - Austin Health
Insulin resistance and beta-cell dysfunction
Obesity development
transgenic and knockout animal models
animal models of obesity
body weight regulation
animal physiology
diet-induced obesity
appetite regulation
science & technology
Barbara Fam White's Profile Picture
Dr

Barbara Fam White

 
Division
Medicine, Dentistry and Health Sciences
 
Primary Interest
Type 2 Diabetes
Barbara Fam White's Profile Picture
Dr

Barbara Fam White

 
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Barbara Fam's  Short Profile
 

Projects

Displaying the 10 most recent projects by Barbara Fam White.

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Exploring the role of the gut in diet-induced obesity resistance.

2020 - 2021
Active
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Why do some people gain weight and others don't? Exploring the role of the gut specific G-protein coupled receptors in obesity development

2019 - 2021
Active
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Exploring the link between gut G-coupled protein receptors (GPRs), the gut microbiome and epigenetic in obesity development

2017 - 2020
Completed
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WHAT CAUSES COMMON OBESITY?

Obesity in Australia is at a crisis point. It is clear that energy-rich environments and an individual’s genes leads to excessive weight gai..

2014 - 2016
Completed
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Investigating the impact of energy-rich environments on susceptibility and resistance to common (diet-induced) obesity

2013 - 2014
Completed
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INVESTIGATING THE IMPACT OF AN ENERGY-RICH ENVIRONMENT ON GENETIC SUSCEPTIBILITY TO OBESITY - WHAT CAUSES COMMON OBESITY?

2013 - 2013
Completed
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WHAT CAUSES COMMON OBESITY?

2012 - 2012
Completed
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INVESTIGATING INSULIN SECRETORY DEFECTS IN A RAT MODEL WITH A PRIMARY DEFECT IN ENDOGENOUS GLUCOSE PRODUCTION.

2011 - 2011
Completed
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Understanding the causes of the current obesity epidemic - Investigation of possible epigenetic mechanisms

2011 - 2011
Completed
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The role of a liver enzyme in controlling body weight

We have shown that fructose-1,6-bisphosphatase (FBPase), an enzyme important in producing sugar from the liver and one that is connected to ..

2009 - 2011
Completed

22

Projects

Project Types

17

Research Grant

4

Internal Research Grant

1

Research Contracts

Scholarly Works

Displaying the 10 most recent scholarly works by Barbara Fam White.

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Restriction of essential amino acids dictates the systemic metabolic response to dietary protein dilution

Yann W Yap, Patricia M Rusu, Andrea Y Chan, Barbara C Fam, Andreas Jungmann, Samantha M Solon-Biet, Christopher K Barlow, Darren J Creek, Cheng Huang, Ralf B Schittenhelm, Bruce Morgan, Dieter Schmoll, Bente Kiens, Matthew DW Piper, Mathias Heikenwaelder, Stephen J Simpson, Stefan Broer, Sofianos Andrikopoulos, Oliver J Mueller, Adam J Rose

Journal article  |  2020  |  Nature Communications

Dietary protein dilution (DPD) promotes metabolic-remodelling and -health but the precise nutritional components driving this resp..

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The androgen receptor in bone marrow progenitor cells negatively regulates fat mass

Patricia K Russell, Salvatore Mangiafico, Barbara C Fam, Michele V Clarke, Evelyn S Marin, Sofianos Andrikopoulos, Kristine M Wiren, Jeffrey D Zajac, Rachel A Davey

Journal article  |  2018  |  Journal of Endocrinology

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Androgens act via the Androgen Receptor (AR) in progenitor cells residing within the bone marrow to reduce fat mass in male mice

Rachel A Davey, Patricia K Russell, Barbara C Fam, Salvatore Mangiafico, Michele V Clarke, Sof Andrikopoulos, Kristine M Wiren, Jeffrey D Zajac

Conference Proceedings  |  2017  |  CLINICAL ENDOCRINOLOGY

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Muscle-specific androgen receptor deletion shows limited actions in myoblasts but not in myofibers in different muscles in vivo

Kesha Rana, Maria WS Chiu, Patricia K Russell, Jarrod P Skinner, Nicole KL Lee, Barbara C Fam, Jeffrey D Zajac, Helen E MacLean

Journal article  |  2016  |  Journal of Molecular Endocrinology

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Identification of ABCC8 as a contributory gene to impaired early-phase insulin secretion in NZO mice

Sofianos Andrikopoulos, Barbara C Fam, Anita Holdsworth, Sherley Visinoni, Zheng Ruan, Maria Stathopoulos, Anne W Thorburn, Christos N Joannides, Michael Cancilla, Lois Balmer, Joseph Proietto, Grant Morahan

Journal article  |  2016  |  Journal of Endocrinology

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Contribution of the hypothalamus and gut to weight gain susceptibility and resistance in mice

Barbara C Fam, Rebecca Sgambellone, Zheng Ruan, Joseph Proietto, Sofianos Andrikopoulos

Journal article  |  2015  |  JOURNAL OF ENDOCRINOLOGY

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High-Fat-Fed Obese Glutathione Peroxidase 1-Deficient Mice Exhibit Defective Insulin Secretion but Protection from Hepatic Steatosis and Liver Damage

Troy L Merry, Melanie Tran, Maria Stathopoulos, Florian Wiede, Barbara Christianne Fam, Garron T Dodd, Iain Clarke, Matthew J Watt, Sofianos Andrikopoulos, Tony Tiganis

Journal article  |  2014  |  Antioxidants & Redox Signaling

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Targeting VEGF-B as a novel treatment for insulin resistance and type 2 diabetes

CE Hagberg, A Mehlem, A Falkevall, L Muhl, BC Fam, H Ortsäter, P Scotney, D Nyqvist, E Samén, L Lu, S Stone-Elander, J Proietto, S Andrikopoulos, A Sjöholm, A Nash, U Eriksson

Journal article  |  2014  |  Diabetes Technology & Therapeutics

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DICARBA MODIFICATION OF INSULIN PROVIDES GREATER GLUCOSE LOWERING EFFECT UNDER NORMAL AND INSULIN RESISTANT STATES, WHILE AVOIDING THE MITOGENIC ACTIVITY OF UNMODIFIED INSULIN

S Andrikopoulos, B van Lierop, BC Fam, B Forbes, A Robinson

Journal article  |  2013  |  DIABETES TECHNOLOGY & THERAPEUTICS

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Response to comment on: Visinoni et al. The role of liver fructose-1,6-bisphosphatase in regulating appetite and adiposity. Diabetes 2012;61:1122-1132

BC Fam, CN Joannides, S Andrikopoulos

Journal article  |  2012  |  Diabetes

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Scholarly Works

Keyword Analysis

Clinical Sciences
Clinical Health (organs, Diseases and Abnormal Conditions)
Clinical (organs, Diseases and Abnormal Conditions)
Biochemistry and Cell Biology
Expanding Knowledge
Medical Biochemistry and Metabolomics
Medical Physiology
Neurosciences
Cardiovascular Medicine and Haematology

Credentials

Positions

Senior Research Fellow - Proietto

Medicine - Austin Health

Full Member

Australian Diabetes Society

Full Member

Australasian Society for the Study of Obesity

Full Member

Australia and New Zealand Bone and Mineral Society

Education

Doctor of Philosophy

University of Melbourne

Bachelor of Science (honours)

University of Melbourne

Bachelor of Agricultural Science

University of Melbourne

Links