Barbara White

Restriction of essential amino acids dictates the systemic metabolic response to dietary protein dilution

Yann W Yap, Patricia M Rusu, Andrea Y Chan, Barbara C Fam, Andreas Jungmann, Samantha M Solon-Biet, Christopher K Barlow, Darren J Creek, Cheng Huang, Ralf B Schittenhelm, Bruce Morgan, Dieter Schmoll, Bente Kiens, Matthew DW Piper, Mathias Heikenwaelder, Stephen J Simpson, Stefan Broer, Sofianos Andrikopoulos, Oliver J Mueller, Adam J Rose

Journal article  |  2020  |  NATURE COMMUNICATIONS

Dietary protein dilution (DPD) promotes metabolic-remodelling and -health but the precise nutritional components driving this resp..

The androgen receptor in bone marrow progenitor cells negatively regulates fat mass

Patricia K Russell, Salvatore Mangiafico, Barbara C Fam, Michele V Clarke, Evelyn S Marin, Sofianos Andrikopoulos, Kristine M Wiren, Jeffrey D Zajac, Rachel A Davey

Journal article  |  2018  |  JOURNAL OF ENDOCRINOLOGY

It is well established that testosterone negatively regulates fat mass in humans and mice; however, the mechanism by which testost..

Androgens act via the Androgen Receptor (AR) in progenitor cells residing within the bone marrow to reduce fat mass in male mice

Rachel A Davey, Patricia K Russell, Barbara C Fam, Salvatore Mangiafico, Michele V Clarke, Sof Andrikopoulos, Kristine M Wiren, Jeffrey D Zajac

Conference Proceedings  |  2017  |  CLINICAL ENDOCRINOLOGY

Muscle-specific androgen receptor deletion shows limited actions in myoblasts but not in myofibers in different muscles in vivo

Kesha Rana, Maria WS Chiu, Patricia K Russell, Jarrod P Skinner, Nicole KL Lee, Barbara C Fam, Jeffrey D Zajac, Helen E MacLean

Journal article  |  2016  |  JOURNAL OF MOLECULAR ENDOCRINOLOGY

The aim of this study was to investigate the direct muscle cell-mediated actions of androgens by comparing two different mouse lin..

Identification of ABCC8 as a contributory gene to impaired early-phase insulin secretion in NZO mice

Sofianos Andrikopoulos, Barbara C Fam, Anita Holdsworth, Sherley Visinoni, Zheng Ruan, Maria Stathopoulos, Anne W Thorburn, Christos N Joannides, Michael Cancilla, Lois Balmer, Joseph Proietto, Grant Morahan

Journal article  |  2016  |  JOURNAL OF ENDOCRINOLOGY

Type 2 diabetes (T2D) is associated with defective insulin secretion, which in turn contributes to worsening glycaemic control and..

Contribution of the hypothalamus and gut to weight gain susceptibility and resistance in mice

Barbara C Fam, Rebecca Sgambellone, Zheng Ruan, Joseph Proietto, Sofianos Andrikopoulos

Journal article  |  2015  |  JOURNAL OF ENDOCRINOLOGY

Obesity susceptibility in humans and in rodent strains varies in response to the consumption of high-energy density (HED) diets. H..

High-Fat-Fed Obese Glutathione Peroxidase 1-Deficient Mice Exhibit Defective Insulin Secretion but Protection from Hepatic Steatosis and Liver Damage

Troy L Merry, Melanie Tran, Maria Stathopoulos, Florian Wiede, Barbara Christianne Fam, Garron T Dodd, Iain Clarke, Matthew J Watt, Sofianos Andrikopoulos, Tony Tiganis

Journal article  |  2014  |  ANTIOXIDANTS & REDOX SIGNALING

AIMS: Reactive oxygen species (ROS) such as H2O2 can promote signaling through the inactivation of protein tyrosine phosphatases (..

Newer therapies for diabetes management.

Satish K Garg, Viral N Shah

Journal article  |  2014  |  Diabetes Technol Ther

DICARBA MODIFICATION OF INSULIN PROVIDES GREATER GLUCOSE LOWERING EFFECT UNDER NORMAL AND INSULIN RESISTANT STATES, WHILE AVOIDING THE MITOGENIC ACTIVITY OF UNMODIFIED INSULIN

S Andrikopoulos, B van Lierop, BC Fam, B Forbes, A Robinson

Journal article  |  2013  |  DIABETES TECHNOLOGY & THERAPEUTICS

Response to comment on: Visinoni et al. The role of liver fructose-1,6-bisphosphatase in regulating appetite and adiposity. Diabetes 2012;61:1122-1132

BC Fam, CN Joannides, S Andrikopoulos

Journal article  |  2012  |  Diabetes