Chris Williams

A 44 channel suprachoroidal retinal prosthesis: initial psychophysical results

Matthew A Petoe, Samuel A Titchener, Mohit N Shivdasani, David AX Nayagam, Stephanie B Epp, Joel Villalobos, Nicholas N Sinclair, Chris E Williams, Nick Barnes, William G Kentler, Maria Kolic, Elizabeth Kate Baglin, Carla J Abbott, Lauren N Ayton, Chi D Luu, Penelope J Allen

Conference Proceedings  |  2019  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

A 44 channel suprachoroidal retinal prosthesis : surgical approach, safety and stability

Penelope J Allen, David AX Nayagam, Stephanie B Epp, Chi D Luu, Nick Barnes, Maria Kolic, Kiera A Young, Elizabeth Kate Baglin, Carla J Abbott, Robert Briggs, Jonathan Yeoh, William G Kentler, Samuel A Titchener, Matthew A Petoe, Chris E Williams

Conference Proceedings  |  2019  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Effect of chronic electrical stimulation with a fully implantable electrode on photoreceptor survival in a retinal degeneration model

Carla J Abbott, David AX Nayagam, Owen Burns, Helen Feng, Ceara McGowan, Robyn H Guymer, Chris E Williams, Penelope J Allen, Chi D Luu

Conference Proceedings  |  2019  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Ring and peg electrodes for minimally-Invasive and long-term sub-scalp EEG recordings

YB Benovitski, A Lai, CC McGowan, O Burns, V Maxim, DAX Nayagam, R Millard, GD Rathbone, MA le Chevoir, RA Williams, DB Grayden, CN May, M Murphy, WJ D'Souza, MJ Cook, CE Williams

Journal article  |  2017  |  Epilepsy Research

A Pre-clinical Model for Safe Retinal Stimulation

David AX Nayagam, Patrick C Thien, Carla J Abbott, Mohit Naresh Shivdasani, Stephanie B Epp, Joel Villalobos, Ceara McGowan, Richard Williams, Chi D Luu, Cesar Salinas-LaRosa, Jonathan Yeoh, Owen Burns, Alice A Brandli, Chris E Williams, Penelope J Allen, Robert K Shepherd

Conference Proceedings  |  2017  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Passive safety outcomes of a preclinical 44-channel suprachoroidal retinal prosthesis

Carla J Abbott, Chi D Luu, David AX Nayagam, Alice Brandli, Jonathan Yeoh, Joel Villalobos, Owen Burns, Stephanie B Epp, Mohit Naresh Shivdasani, Patrick C Thien, Ceara McGowan, Richard Williams, Robyn H Guymer, Chris E Williams, Robert K Shepherd, Penelope J Allen

Conference Proceedings  |  2017  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Safety and efficacy of explanting or replacing suprachoroidal electrode arrays in a feline model

Ronald T Leung, David AX Nayagam, Richard A Williams, Penelope J Allen, Cesar M Salinas-La Rosa, Chi D Luu, Mohit N Shivdasani, Lauren N Ayton, Meri Basa, Jonathan Yeoh, Alexia L Saunders, Robert K Shepherd, Chris E Williams

Journal article  |  2015  |  Clinical & Experimental Ophthalmology

Preclinical evaluation of a miniaturized Deep Brain Stimulation electrode lead

Joel Villalobos, James B Fallon, Peter M McNeill, Rachel K Allison, Olivier Bibari, Chris E Williams, Hugh J McDermott

Conference Proceedings  |  2015  |  2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)

First-in-Human Trial of a Novel Suprachoroidal Retinal Prosthesis

Lauren N Ayton, Peter J Blamey, Robyn H Guymer, Chi D Luu, David AX Nayagam, Nicholas C Sinclair, Mohit N Shivdasani, Jonathan Yeoh, Mark F McCombe, Robert J Briggs, Nicholas L Opie, Joel Villalobos, Peter N Dimitrov, Mary Varsamidis, Matthew A Petoe, Chris D McCarthy, Janine G Walker, Nick Barnes, Anthony N Burkitt, Chris E Williams, et al.

Journal article  |  2014  |  PLoS ONE

Virtual Electrodes by Current Steering in Retinal Prostheses

Gerald Dumm, James B Fallon, Chris E Williams, Mohit N Shivdasani

Journal article  |  2014  |  Investigative Ophthalmology & Visual Science

Spatiotemporal Interactions in the Visual Cortex Following Paired Electrical Stimulation of the Retina

Rosemary Cicione, James B Fallon, Graeme D Rathbone, Chris E Williams, Mohit N Shivdasani

Journal article  |  2014  |  Investigative Ophthalmology & Visual Science

Development of a surgical procedure for implantation of a prototype suprachoroidal retinal prosthesis

Alexia L Saunders, Chris E Williams, Wilson Heriot, Robert Briggs, Jonthan Yeoh, David AX Nayagam, Mark McCombe, Joel Villalobos, Owen Burns, Chi D Luu, Lauren N Ayton, Michelle McPhedran, Nicholas L Opie, Ceara McGowan, Robert K Shepherd, Robyn Guymer, Penelope J Allen

Journal article  |  2014  |  Clinical & Experimental Ophthalmology

Cortical activation following chronic passive implantation of a wide-field suprachoroidal retinal prosthesis

Joel Villalobos, James B Fallon, David AX Nayagam, Mohit N Shivdasani, Chi D Luu, Penelope J Allen, Robert K Shepherd, Chris E Williams

Journal article  |  2014  |  Journal of Neural Engineering

Chronic Electrical Stimulation with a Suprachoroidal Retinal Prosthesis: A Preclinical Safety and Efficacy Study

David AX Nayagam, Richard A Williams, Penelope J Allen, Mohit N Shivdasani, Chi D Luu, Cesar M Salinas-LaRosa, Sue Finch, Lauren N Ayton, Alexia L Saunders, Michelle McPhedran, Ceara McGowan, Joel Villalobos, James B Fallon, Andrew K Wise, Jonathan Yeoh, Jin Xu, Helen Feng, Rodney Millard, Melanie McWade, Patrick C Thien, et al.

Journal article  |  2014  |  PLoS One

Suprachoroidal electrical stimulation: effects of stimulus pulse parameters on visual cortical responses

Sam E John, Mohit N Shivdasani, Chris E Williams, John W Morley, Robert K Shepherd, Graeme D Rathbone, James B Fallon

Journal article  |  2013  |  Journal of Neural Engineering

Visual prostheses for the blind

Robert K Shepherd, Mohit N Shivdasani, David AX Nayagam, Christopher E Williams, Peter J Blamey

Journal article  |  2013  |  Trends in Biotechnology

Techniques for Processing Eyes Implanted With a Retinal Prosthesis for Localized Histopathological Analysis

David AX Nayagam, Ceara McGowan, Joel Villalobos, Richard A Williams, Cesar Salinas-LaRosa, Penny McKelvie, Irene Lo, Meri Basa, Justin Tan, Chris E Williams

Journal article  |  2013  |  Journal of Visualized Experiments

A Wide-Field Suprachoroidal Retinal Prosthesis Is Stable and Well Tolerated Following Chronic Implantation

Joel Villalobos, David AX Nayagam, Penelope J Allen, Penelope McKelvie, Chi D Luu, Lauren N Ayton, Alexia L Freemantle, Michelle McPhedran, Meri Basa, Ceara C McGowan, Robert K Shepherd, Chris E Williams

Journal article  |  2013  |  Investigative Ophthalmology and Visual Science

Visual cortex responses to suprachoroidal electrical stimulation of the retina: effects of electrode return configuration

Rosemary Cicione, Mohit N Shivdasani, James B Fallon, Chi D Luu, Penny J Allen, Graeme D Rathbone, Robert K Shepherd, Chris E Williams

Journal article  |  2012  |  Journal of Neural Engineering

Development of a surgical approach for a wide-view suprachoroidal retinal prosthesis: evaluation of implantation trauma

Joel Villalobos, Penelope J Allen, Mark F McCombe, Meera Ulaganathan, Ehud Zamir, David C Ng, Robert K Shepherd, Chris E Williams

Journal article  |  2012  |  Graefe's Archive for Clinical and Experimental Ophthalmology

Inhibition of MMP-9 Activity following Hypoxic Ischemia in the Developing Brain Using a Highly Specific Inhibitor

Himani S Ranasinghe, Arjan Scheepens, Ernest Sirimanne, Murray D Mitchell, Christopher E Williams, Mhoyra Fraser

Journal article  |  2012  |  Developmental Neuroscience

Cot-Side Electroencephalography Monitoring is Not Clinically Useful in the Detection of Mild Neonatal Hypoglycemia

Deborah L Harris, Philip J Weston, Christopher E Williams, Anthony B Pleasants, Malcolm R Battin, Claire G Spooner, Jane E Harding

Journal article  |  2011  |  J. Pediatr.

An automated system for rapid evaluation of high-density electrode arrays in neural prostheses

Sam E John, Mohit N Shivdasani, James Leuenberger, James B Fallon, Robert K Shepherd, Rodney E Millard, Graeme D Rathbone, Chris E Williams

Journal article  |  2011  |  Journal of Neural Engineering

Biocompatibility of Immobilized Aligned Carbon Nanotubes

David AX Nayagam, Richard A Williams, Jun Chen, Kylie A Magee, Jennifer Irwin, Justin Tan, Peter Innis, Ronald T Leung, Sue Finch, Chris E Williams, Graeme M Clark, Gordon G Wallace

Journal article  |  2011  |  Small

Cot-side electroencephalography for outcome prediction in preterm infants: observational study

Claire R West, Jane E Harding, Chris E Williams, Melinda Nolan, Malcolm R Battin

Journal article  |  2011  |  Archives of Disease in Childhood - Fetal and Neonatal Edition

Wireless power delivery for retinal prostheses

David C Ng, Chris E Williams, Penny J Allen, Shun Bai, Clive S Boyd, Hamish Meffin, Mark E Halpern, Efstratios Skafidas

Conference Proceedings  |  2011  |  Proceedings the 33rd Annual International IEEE EMBC Conference

Evaluation of stimulus parameters and electrode geometry for an effective suprachoroidal retinal prosthesis

Mohit N Shivdasani, Chi D Luu, Rosemary Cicione, James B Fallon, Penny J Allen, James Leuenberger, Gregg J Suaning, Nigel H Lovell, Robert K Shepherd, Chris E Williams

Journal article  |  2010  |  Journal of Neural Engineering

Delayed and chronic treatment with growth hormone after endothelin-induced stroke in the adult rat

Praneeti Pathipati, Andrzej Surus, Christopher Edward Williams, Arjan Scheepens

Journal article  |  2009  |  Behav. Brain Res.

Growth hormone receptor immunoreactivity is increased in the subventricular zone of juvenile rat brain after focal ischemia: A potential role for growth hormone in injury-induced neurogenesis

Larissa Joy Christophidis, Thorsten Gorba, Malin Gustavsson, Chris Edward Williams, George Arthur Werther, Vincenzo Carlo Russo, Arjan Scheepens

Journal article  |  2009  |  Growth Hormone & IGF Research

Pulling the plug on ad hoc critical incident training

DW Wheeler, CE Williams, AF Merry

Journal article  |  2009  |  British Journal of Anaesthesia

PROTEOLYTIC ACTIVITY DURING CORTICAL DEVELOPMENT IS DISTINCT FROM THAT INVOLVED IN HYPOXIC ISCHEMIC INJURY

HS Ranasinghe, CE Williams, LJ Christophidis, MD Mitchell, M Fraser, A Scheepens

Journal article  |  2009  |  Neuroscience

Cot-Side Electro-Encephalography and Interstitial Glucose Monitoring during Insulin-Induced Hypoglycaemia in Newborn Lambs

Deborah L Harris, Malcolm R Battin, Chris E Williams, Philip J Weston, Jane E Harding

Journal article  |  2009  |  Neonatology

Extracellular amino acids and lipid peroxidation products in periventricular white matter during and after cerebral ischemia in preterm fetal sheep

M Fraser, L Bennet, PL Van Zijl, TJ Mocatta, CE Williams, PD Gluckman, CC Winterbourn, AJ Gunn

Journal article  |  2008  |  Journal of Neurochemistry

Selective losses of brainstem catecholamine neurons after hypoxia-ischemia in the immature rat pup

Kathryn M Buller, Julie A Wixey, Praneeti Pathipati, Michelle Carty, Paul B Colditz, Christopher E Williams, Arjan Scheepens

Journal article  |  2008  |  Pediatr. Res.

The electroencephalograph during anesthesia and emergence in infants and children

Andrew J Davidson, Steven M Sale, Connie Wong, Stephen Mckeever, Suzette Sheppard, Zeke Chan, Chris Williams

Journal article  |  2008  |  Pediatric Anesthesia

Developmental changes and injury induced disruption of the radial organization of the cortex in the immature rat brain revealed by in vivo diffusion tensor MRI

St Phane V Sizonenko, Emily J Camm, Joel R Garbow, Stephan E Maier, Terrie E Inder, Chris E Williams, Jeffrey J Neil, Petra S Huppi

Journal article  |  2007  |  Cerebral Cortex

Prolactin is involved in glial responses following a focal injury to the juvenile rat brain

TAE Moderscheim, T Gorba, P Pathipati, IC Kokay, DR Grattan, CE Williams, A Scheepens

Journal article  |  2007  |  Neuroscience

Distinct neuronal growth hormone receptor ligand specificity in the rat brain

Tanja Anna Elisabeth Moderscheim, Larissa Joy Christophidis, Chris Edward Williams, Arjan Scheepens

Journal article  |  2007  |  Brain Research

Regional specificity of magnetic resonance imaging and histopathology following cerebral ischemia in preterm fetal sheep

Mhoyra Fraser, Laura Bennet, Rachel Helliwell, Scott Wells, Christopher Williams, Peter Gluckman, Alistair J Gunn, Terrie Inder

Journal article  |  2007  |  Reproductive Sciences

Seizure detection algorithm for neonates based on wave-sequence analysis

Michael A Navakatikyan, Paul B Colditz, Chris J Burke, Terrie E Inder, Jane Richmond, Christopher E Williams

Journal article  |  2006  |  Clinical Neurophysiology

Seizure detection algorithm for neonates based on wave-sequence analysis

Michael A Navakatikyan, Paul B Colditz, Chris J Burke, Terrie E Inder, Jane Richmond, Christopher E Williams

Journal article  |  2006  |  Clinical Neurophysiology

Early low cardiac output is associated with compromised electroencephalographic activity in very preterm infants

CR West, AM Groves, CE Williams, JE Harding, JR Skinner, CA Kuschel, MR Battin

Journal article  |  2006  |  Pediatric Research

Early evidence of a regulated response to hypoxaemia in sheep that preserves the brain cortex

D Gorman, HY Lin, C Williams

Journal article  |  2006  |  Neuroscience Letters

Quantitative electroencephalographic patterns in normal preterm infants over the first week after birth

CR West, JE Harding, CE Williams, MI Gunning, MR Battin

Journal article  |  2006  |  Early Human Development

Comparison of quantitative measures and neurophysiologist assessment using cotside EEG monitors to predict outcome in preterm infants

CR West, MA Nolan, CE Williams, JE Harding, JA Dezoete, MR Battin

Conference Proceedings  |  2005  |  Pediatric Research

A regularity-based seizure detection algorithm for neonates

MA Navakatikyan, PB Colditz, CJ Burke, TE Inder, J Richmond, CE Williams

Conference Proceedings  |  2005  |  Pediatric Research

Early quantitative electroencepralographic measures of continuity are associated with neurodevelopmental outcome at 18 months in preterm infants

CR West, MR Battin, CE Williams, JA Dezoete, JE Harding

Conference Proceedings  |  2005  |  Pediatric Research

Echocardiographic blood flow measures are associated with quantitative EEG parameters in preterm infants in the first 48 hours after birth

CR West, AM Groves, JE Harding, CE Williams, CA Kuschel, JR Skinner, MR Battin

Conference Proceedings  |  2005  |  Pediatric Research

Distinctive neuropathologic alterations in the deep layers of the parietal cortex after moderate ischemic-hypoxic injury in the P3 immature rat brain

SV Sizonenko, JZ Kiss, T Inder, PD Gluckman, CE Williams

Journal article  |  2005  |  Pediatric Research

Blockade of haem oxygenase and nitric oxide synthetase causes cortical dysfunction in sheep exposed to carbon monoxide

D Gorman, HY Lin, C Williams

Journal article  |  2005  |  Toxicology

Cortical electroencephalogram suppression is associated with post-ischemic cortical injury in 0.65 gestation fetal sheep

M Fraser, L Bennet, M Gunning, C Williams, PD Gluckman, S George, AJ Gunn

Journal article  |  2005  |  Developmental Brain Research

Haemodynamically significant PDA is associated with changes in advanced EEG measures in preterm infants

C Wong, RW Hunt, C Williams, S Rogerson, TE Inder

Conference Proceedings  |  2004  |  PEDIATRIC RESEARCH

Spectral Edge Frequency measurements in the first week predict Hammersmith neonatal neurology score near term in a cohort of premature infants

CR West, CE Williams, JE Harding, MR Battin

Conference Proceedings  |  2004  |  PEDIATRIC RESEARCH

Changes in novel electroencephalography measurements over the first week after birth in premature infants

CR West, CE Williams, JE Harding, MR Battin

Conference Proceedings  |  2004  |  PEDIATRIC RESEARCH

Radial organisation of the cortex in the immature rat brain revealed by diffusion tensor MRI (DTI)

SV Sizonenko, S Zimine, JR Garbow, S Maier, CE Williams, TE Inder, JF Neil, PS Huppi

Conference Proceedings  |  2004  |  PEDIATRIC RESEARCH

A lignocaine infusion worsens the leukoencephalopathy due to a carbon monoxide exposure in sheep

D Gorman, YL Huang, C Williams

Journal article  |  2003  |  Toxicology

Astrocytes and microglia activation after moderate hypoxia-ischemia (HI) in the P3 rat brain

S Sizonenko, J Kiss, P Gluckman, T Inder, C Williams

Conference Proceedings  |  2003  |  PEDIATRIC RESEARCH

Cellular damage and gliosis after mild hypoxia-ischemia in P3 rat brain.

S Sizonenko, C Williams, T Inder, P Gluckman

Conference Proceedings  |  2002  |  PEDIATRIC RESEARCH

A narcotic dose of carbon monoxide induces neuronal haeme oxygenase and nitric oxide synthetase in sheep

D Gorman, YL Huang, C Williams

Journal article  |  2002  |  Toxicology

Time-course of cellular and axonal damage after mild acute hypoxia-ischemia in P3 rat brain

S Sizonenko, C Williams, T Inder, P Gluckman

Conference Proceedings  |  2002  |  DEVELOPMENTAL NEUROSCIENCE

The relationship of amplitude integrated EEG measures of spectral edge frequency to gestational age

TE Inder, CE Williams, ML Gunning, JJ Volpe, PD Gluckman

Journal article  |  2002  |  PEDIATRIC RESEARCH

Neuroprotective effects of the N-terminal tripeptide of IGF-1, glycine-proline-glutamate, in the immature rat brain after hypoxic-ischemic injury

SV Sizonenko, ES Sirimanne, CE Williams, PD Gluckman

Journal article  |  2001  |  Brain Research

Prolonged exposure to one percent carbon monoxide causes a leucoencephalopathy in un-anaesthetised sheep

DF Gorman, YL Huang, C Williams

Journal article  |  2001  |  Toxicology

ST waveform changes during repeated umbilical cord occlusions in near-term fetal sheep

JA Westgate, L Bennet, C Brabyn, CE Williams, AJ Gunn

Journal article  |  2001  |  American Journal of Obstetrics and Gynecology

Growth hormone as a neuronal rescue factor during recovery from CNS injury

A Scheepens, ES Sirimanne, BH Breier, RG Clark, PD Gluckman, CE Williams

Journal article  |  2001  |  Neuroscience