Nancy Wang

Integrative omics identifies conserved and pathogen-specific responses of sepsis-causing bacteria.

Andre Mu, William P Klare, Sarah L Baines, CN Ignatius Pang, Romain Guérillot, Nichaela Harbison-Price, Nadia Keller, Jonathan Wilksch, Nguyen Thi Khanh Nhu, Minh-Duy Phan, Bernhard Keller, Brunda Nijagal, Dedreia Tull, Saravanan Dayalan, Hwa Huat Charlie Chua, Dominik Skoneczny, Jason Koval, Abderrahman Hachani, Anup D Shah, Nitika Neha, et al.

Journal article  |  2023  |  Nat Commun

Even in the setting of optimal resuscitation in high-income countries severe sepsis and septic shock have a mortality of 20-40%, w..

LPS O Antigen Plays a Key Role in Klebsiella pneumoniae Capsule Retention

Shweta Singh, Jonathan J Wilksch, Rhys A Dunstan, Anna Mularski, Nancy Wang, Dianna Hocking, Leila Jebeli, Hanwei Cao, Abigail Clements, Adam WJ Jenney, Trevor Lithgow, Richard A Strugnell

Journal article  |  2022  |  MICROBIOLOGY SPECTRUM

Despite the importance of encapsulation in bacterial pathogenesis, the biochemical mechanisms and forces that underpin retention o..

Genomic epidemiology of Salmonella Typhi in Central Division, Fiji, 2012 to 2016

Mark R Davies, Sebastian Duchene, Mary Valcanis, Aaron P Jenkins, Adam Jenney, Varanisese Rosa, Andrew J Hayes, Aneley Getahun Strobel, Liam McIntyre, Jake A Lacey, Elizabeth J Klemm, Vanessa K Wong, Aalisha Sahukhan, Helen Thomson, Andrew Page, Dianna Hocking, Nancy Wang, Litia Tudravu, Eric Rafai, Gordon Dougan, et al.

Journal article  |  2022  |  LANCET REGIONAL HEALTH-WESTERN PACIFIC

BACKGROUND: Typhoid fever is endemic in some Pacific Island Countries including Fiji and Samoa yet genomic surveillance is not rou..

CD4( ) T cell immunity to Salmonella is transient in the circulation

Newton G Peres, Nancy Wang, Paul Whitney, Sven Engel, Meghanashree M Shreenivas, Ian Comerford, Dianna M Hocking, Anna B Erazo, Irmgard Foerster, Andreas Kupz, Thomas Gebhardt, Shaun R McColl, Stephen J McSorley, Sammy Bedoui, Richard A Strugnell

Journal article  |  2021  |  PLOS PATHOGENS

While Salmonella enterica is seen as an archetypal facultative intracellular bacterial pathogen where protection is mediated by CD..

CCL17-expressing dendritic cells in the intestine are preferentially infected by Salmonella but CCL17 plays a redundant role in systemic dissemination

Anna B Erazo, Nancy Wang, Lena Standke, Adrian D Semeniuk, Lorenz Fuelle, Sevgi C Cengiz, Manja Thiem, Heike Weighardt, Richard A Strugnell, Irmgard Foerster

Journal article  |  2021  |  IMMUNITY INFLAMMATION AND DISEASE

INTRODUCTION: Salmonella spp. are a recognized and global cause of serious health issues from gastroenteritis to invasive disease...

Sustained neutralising antibodies in the Wuhan population suggest durable protection against SARS-CoV-2

Richard Strugnell, Nancy Wang

Journal article  |  2021  |  LANCET

Optimal preparation of SARS-CoV-2 viral transport medium for culture

Julie McAuley, Claire Fraser, Elena Paraskeva, Elizabeth Trajcevska, Michelle Sait, Nancy Wang, Eric Bert, Damian Purcell, Richard Strugnell

Journal article  |  2021  |  VIROLOGY JOURNAL

INTRODUCTION: The sudden arrival of the COVID-19 pandemic placed significant stresses on supply chains including viral transport m..

Flexible Usage and Interconnectivity of Diverse Cell Death Pathways Protect against Intracellular Infection

Marcel Doerflinger, Yexuan Deng, Paul Whitney, Ranja Salvamoser, Sven Engel, Andrew J Kueh, Lin Tai, Annabell Bachem, Elise Gressier, Niall D Geoghegan, Stephen Wilcox, Kelly L Rogers, Alexandra L Garnham, Michael A Dengler, Stefanie M Bader, Gregor Ebert, Jaclyn S Pearson, Dominic De Nardo, Nancy Wang, Chenying Yang, et al.

Journal article  |  2020  |  IMMUNITY

Programmed cell death contributes to host defense against pathogens. To investigate the relative importance of pyroptosis, necropt..

CCR2 enhances CD25 expression by FoxP3( ) regulatory T cells and regulates their abundance independently of chemotaxis and CCR2( ) myeloid cells

Yifan Zhan, Nancy Wang, Ajithkumar Vasanthakumar, Yuxia Zhang, Michael Chopin, Stephen L Nutt, Axel Kallies, Andrew M Lew

Journal article  |  2020  |  CELLULAR & MOLECULAR IMMUNOLOGY

A wide array of chemokine receptors, including CCR2, are known to control Treg migration. Here, we report that CCR2 regulates Treg..

Staphylococcus aureus small colony variants impair host immunity by activating host cell glycolysis and inducing necroptosis

Tania Wong Fok Lung, Ian R Monk, Karen P Acker, Andre Mu, Nancy Wang, Sebastian A Riquelme, Silvia Pires, Loreani P Noguera, Felix Dach, Stanislaw J Gabryszewski, Benjamin P Howden, Alice Prince

Journal article  |  2020  |  NATURE MICROBIOLOGY

Staphylococcus aureus small colony variants (SCVs) are frequently associated with chronic infection, yet they lack expression of m..