Wendyl D'Souza

The influence of comorbidity on mortality in patients with epilepsy and psychogenic non-epileptic seizures.

Michael Tan, Neil Pearce, Aurelio Tobias, Mark J Cook, Wendyl J D'Souza

Journal article  |  2023  |  Epilepsia

OBJECTIVE: This study aims to determine the contribution of comorbidly to excess PNES mortality. METHODS: Retrospective cohort stu..

A cross-sectional investigation of cognition and epileptiform discharges in juvenile absence epilepsy.

Anita L Dharan, Stephen C Bowden, Andre Peterson, Alan Lai, Udaya Seneviratne, Gabriel Dabscheck, Ewan Nurse, Amy Loughman, Nicholas Parsons, Wendyl J D'Souza

Journal article  |  2023  |  Epilepsia

OBJECTIVES: Despite the prevalence of cognitive symptoms in the idiopathic generalized epilepsies (IGEs), cognitive dysfunction in..

Sleep and seizure risk in epilepsy: bed and wake times are more important than sleep duration.

Rachel E Stirling, Cindy M Hidajat, David B Grayden, Wendyl J D'Souza, Jodie Naim-Feil, Katrina L Dell, Logan D Schneider, Ewan Nurse, Dean Freestone, Mark J Cook, Philippa J Karoly

Journal article  |  2022  |  Brain

Sleep duration, sleep deprivation and the sleep-wake cycle are thought to play an important role in the generation of epileptic ac..

Individualised prediction of drug resistance and seizure recurrence after medication withdrawal in people with juvenile myoclonic epilepsy: A systematic review and individual participant data meta-analysis.

Remi Stevelink, Dania Al-Toma, Floor E Jansen, Herm J Lamberink, Ali A Asadi-Pooya, Mohsen Farazdaghi, Gonçalo Cação, Sita Jayalakshmi, Anuja Patil, Çiğdem Özkara, Şenay Aydın, Joanna Gesche, Christoph P Beier, Linda J Stephen, Martin J Brodie, Gopeekrishnan Unnithan, Ashalatha Radhakrishnan, Julia Höfler, Eugen Trinka, Roland Krause, et al.

Journal article  |  2022  |  EClinicalMedicine

BACKGROUND: A third of people with juvenile myoclonic epilepsy (JME) are drug-resistant. Three-quarters have a seizure relapse whe..

Increased cortical thickness in nodes of the cognitive control and default mode networks in psychosis of epilepsy

James Allebone, Sarah J Wilson, Richard CJ Bradlow, Jerome Maller, Terry O' Brien, Saul A Mullen, Mark Cook, Sophia J Adams, Simon Vogrin, David N Vaughan, Alan Connelly, Patrick Kwan, Samuel F Berkovic, Wendyl J DSouza, Graeme Jackson, Dennis Velakoulis, Richard A Kanaan

Journal article  |  2022  |  SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

OBJECTIVE: To explore the cortical morphological associations of the psychoses of epilepsy. METHODS: Psychosis of epilepsy (POE) h..

Semiologic differences between bilateral tonic-clonic seizures of focal onset and generalized onset.

Udaya Seneviratne, Harry Christie, Wendyl D'Souza, Mark Cook

Journal article  |  2022  |  Epilepsy Behav

BACKGROUND: Focal semiologies have been described in idiopathic generalized epilepsies (IGE) and generalized-onset bilateral tonic..

Second-line immunotherapy and functional outcomes in autoimmune encephalitis: A systematic review and individual patient data meta-analysis.

Amy Halliday, Andrew Duncan, Mike Cheung, Ray C Boston, Metha Apiwattanakul, Ximena Camacho, Stephen Bowden, Wendyl D'Souza

Journal article  |  2022  |  Epilepsia

Autoimmune encephalitis (AE) is a neurological disorder caused by autoimmune attack on cerebral proteins. Experts currently recomm..

Perampanel for the treatment of patients with myoclonic seizures in clinical practice: Evidence from the PERMIT study.

Wendyl D'Souza, Taoufik Alsaadi, Javier Montoya, Mar Carreño, Carlo Di Bonaventura, Rajiv Mohanraj, Takamichi Yamamoto, Rob McMurray, Oliver Shastri, Vicente Villanueva, undefined PERMIT study group

Journal article  |  2022  |  Seizure

PURPOSE: To investigate the effectiveness, safety and tolerability of perampanel (PER) in treating myoclonic seizures in clinical ..

Preclinical safety study of a fully implantable, sub-scalp ring electrode array for long-term EEG recordings

Yuri B Benovitski, Alan Lai, Alexia Saunders, Ceara C McGowan, Owen Burns, David AX Nayagam, Rodney Millard, Mark Harrison, Graeme D Rathbone, Richard A Williams, Clive N May, Michael Murphy, Wendyl J D'Souza, Mark J Cook, Chris E Williams

Journal article  |  2022  |  JOURNAL OF NEURAL ENGINEERING

OBJECTIVE: Long-term electroencephalogram (EEG) recordings can aid diagnosis and management of various neurological conditions suc..

Prevalence, risk factors, and prognosis of drug-resistant epilepsy in autoimmune encephalitis

Robb Wesselingh, James Broadley, Katherine Buzzard, David Tarlinton, Udaya Seneviratne, Chris Kyndt, Jim Stankovich, Paul Sanfilippo, Cassie Nesbitt, Wendyl D'Souza, Richard Macdonell, Helmut Butzkueven, Terence J O'Brien, Mastura Monif

Journal article  |  2022  |  EPILEPSY & BEHAVIOR

OBJECTIVE: To evaluate the prevalence and biomarkers of drug-resistant epilepsy (DRE) in patients with autoimmune encephalitis (AI..