Wendyl D'Souza

Resting-state functional connectivity in the idiopathic generalized epilepsies: A systematic review and meta-analysis of EEG and MEG studies

Anita L Dharan, Stephen C Bowden, Alan Lai, Andre DH Peterson, Mike W-L Cheung, Wessel Woldman, Wendyl J D'Souza

Journal article  |  2021  |  EPILEPSY & BEHAVIOR

For idiopathic generalized epilepsies (IGE), brain network analysis is emerging as a biomarker for potential use in clinical care...

Association of Short-term Heart Rate Variability and Sudden Unexpected Death in Epilepsy.

Shobi Sivathamboo, Daniel Friedman, Juliana Laze, Russell Nightscales, Zhibin Chen MBiostat, Levin Kuhlmann, Sasha Devore, Vaughan Macefield, Patrick Kwan, Wendyl D'Souza, Samuel F Berkovic, Piero Perucca, Terence J O'Brien, Orrin Devinsky, undefined MS-BioS study group

Journal article  |  2021  |  Neurology

OBJECTIVE: We compared heart rate variability (HRV) in sudden unexpected death in epilepsy (SUDEP) cases and living epilepsy contr..

Association Between Psychiatric Comorbidities and Mortality in Epilepsy

Gerard Tao, Clarissa Auvrez, Russell Nightscales, Sarah Barnard, Lara McCartney, Charles B Malpas, Piero Perucca, Zhibin Chen, Sophia Adams, Anne McIntosh, Sophia Ignatiadis, Patrick O'Brien, Mark J Cook, Patrick Kwan, Samuel F Berkovic, Wendyl D'Souza, Dennis Velakoulis, Terence J O'Brien

Journal article  |  2021  |  NEUROLOGY-CLINICAL PRACTICE

Objective: To explore the impact of psychiatric comorbidities on all-cause mortality in adults with epilepsy from a cohort of pati..

Long-term mood, quality of life, and seizure freedom in intracranial EEG epilepsy surgery

Oshi Swarup, Alexandra Waxmann, Jocelyn Chu, Simon Vogrin, Alan Lai, Joshua Laing, James Barker, Linda Seiderer, Sophia Ignatiadis, Chris Plummer, Ross Carne, Udaya Seneviratne, Mark Cook, Michael Murphy, Wendyl D'Souza

Journal article  |  2021  |  EPILEPSY & BEHAVIOR

OBJECTIVES: To determine the long-term outcomes in patients undergoing intracranial EEG (iEEG) evaluation for epilepsy surgery in ..

Multiday cycles of heart rate are associated with seizure likelihood: An observational cohort study

Philippa J Karoly, Rachel E Stirling, Dean R Freestone, Ewan S Nurse, Matias Maturana, Amy J Halliday, Andrew Neal, Nicholas M Gregg, Benjamin H Brinkmann, Mark P Richardson, Andre La Gerche, David B Grayden, Wendyl D'Souza, Mark J Cook

Journal article  |  2021  |  EBIOMEDICINE

BACKGROUND: Circadian and multiday rhythms are found across many biological systems, including cardiology, endocrinology, neurolog..

PERMIT study: a global pooled analysis study of the effectiveness and tolerability of perampanel in routine clinical practice

Vicente Villanueva, Wendyl D'Souza, Hiroko Goji, Dong Wook Kim, Claudio Liguori, Rob McMurray, Imad Najm, Estevo Santamarina, Bernhard J Steinhoff, Pavel Vlasov, Tony Wu, Eugen Trinka

Journal article  |  2021  |  JOURNAL OF NEUROLOGY

The PERaMpanel pooled analysIs of effecTiveness and tolerability (PERMIT) study was a pooled analysis of data from 44 real-world s..

Seizure Forecasting Using a Novel Sub-Scalp Ultra-Long Term EEG Monitoring System

Rachel E Stirling, Matias Maturana, Philippa J Karoly, Ewan S Nurse, Kate McCutcheon, David B Grayden, Steven G Ringo, John M Heasman, Rohan J Hoare, Alan Lai, Wendyl D'Souza, Udaya Seneviratne, Linda Seiderer, Karen J McLean, Kristian J Bulluss, Michael Murphy, Benjamin H Brinkmann, Mark P Richardson, Dean R Freestone, Mark J Cook

Journal article  |  2021  |  FRONTIERS IN NEUROLOGY

Accurate identification of seizure activity, both clinical and subclinical, has important implications in the management of epilep..

Epileptic Seizure Cycles: Six Common Clinical Misconceptions

Philippa J Karoly, Dean R Freestone, Dominique Eden, Rachel E Stirling, Lyra Li, Pedro F Vianna, Matias I Maturana, Wendyl J D'Souza, Mark J Cook, Mark P Richardson, Benjamin H Brinkmann, Ewan S Nurse

Journal article  |  2021  |  FRONTIERS IN NEUROLOGY

Computer-assisted EEG diagnostic review for idiopathic generalized epilepsy

Shannon Clarke, Philippa J Karoly, Ewan Nurse, Udaya Seneviratne, Janelle Taylor, Rory Knight-Sadler, Robert Kerr, Braden Moore, Patrick Hennessy, Dulini Mendis, Claire Lim, Jake Miles, Mark Cook, Dean R Freestone, Wendyl D'Souza

Journal article  |  2021  |  EPILEPSY & BEHAVIOR

Epilepsy diagnosis can be costly, time-consuming, and not uncommonly inaccurate. The reference standard diagnostic monitoring is c..

Forecasting Seizure Likelihood With Wearable Technology

Rachel E Stirling, David B Grayden, Wendyl D'Souza, Mark J Cook, Ewan Nurse, Dean R Freestone, Daniel E Payne, Benjamin H Brinkmann, Tal Pal Attia, Pedro F Viana, Mark P Richardson, Philippa J Karoly

Journal article  |  2021  |  FRONTIERS IN NEUROLOGY

The unpredictability of epileptic seizures exposes people with epilepsy to potential physical harm, restricts day-to-day activitie..