Wendyl d'Souza

Enlarged hippocampal fissure in psychosis of epilepsy

James Allebone, Richard A Kanaan, Jerome J Maller, Terrence O'Brien, Saul Mullen, Mark Cook, Sophie Adams, Simon Vogrin, David Vaughan, Alan Connelly, Patrick Kwan, Samuel F Berkovic, Wendyl D'Souza, Graeme Jackson, Dennis Velakoulis, Sarah J Wilson

Journal article  |  2020  |  Epilepsy & Behavior

Psychosis of epilepsy (POE) can be a devastating condition, and its neurobiological basis remains unclear. In a previous study, we..

Domino-like transient dynamics at seizure onset in epilepsy

Jennifer Creaser, Congping Lin, Thomas Ridler, Jonathan T Brown, Wendyl D'Souza, Udaya Seneviratne, Mark Cook, John R Terry, Krasimira Tsaneva-Atanasova

Journal article  |  2020  |  PLoS Computational Biology

The International League Against Epilepsy (ILAE) groups seizures into "focal", "generalized" and "unknown" based on whether the se..

Mortality in patients with psychogenic nonepileptic seizures

Russell Nightscales, Lara McCartney, Clarissa Auvrez, Gerard Tao, Sarah Barnard, Charles B Malpas, Piero Perucca, Anne McIntosh, Zhibin Chen, Shobi Sivathamboo, Sophia Ignatiadis, Simon Jones, Sophia Adams, Mark J Cook, Patrick Kwan, Dennis Velakoulis, Wendyl D'Souza, Samuel F Berkovic, Terence J O'Brien

Journal article  |  2020  |  Neurology

OBJECTIVE: To investigate the hypothesis that patients diagnosed with psychogenic nonepileptic seizures (PNES) on video-EEG monito..

Critical slowing down as a biomarker for seizure susceptibility.

Matias I Maturana, Christian Meisel, Katrina Dell, Philippa J Karoly, Wendyl D'Souza, David B Grayden, Anthony N Burkitt, Premysl Jiruska, Jan Kudlacek, Jaroslav Hlinka, Mark J Cook, Levin Kuhlmann, Dean R Freestone

Journal article  |  2020  |  Nature Communications

The human brain has the capacity to rapidly change state, and in epilepsy these state changes can be catastrophic, resulting in lo..

Anti-seizure therapy with a long-term, implanted intra-cerebroventricular delivery system for drug-resistant epilepsy: A first-in-man study.

Mark Cook, Michael Murphy, Kristian Bulluss, Wendyl D'Souza, Chris Plummer, Emma Priest, Catherine Williams, Ashwini Sharan, Robert Fisher, Sharon Pincus, Eric Distad, Tom Anchordoquy, Dan Abrams

Journal article  |  2020  |  EClinicalMedicine

Background: A clinical feasibility study was undertaken at a single center of long-term intra-cerebroventricular drug delivery of ..

"Sleep Surge": The impact of sleep onset and offset on epileptiform discharges in idiopathic generalized epilepsies

Udaya Seneviratne, Alan Lai, Mark Cook, Wendyl D'Souza, Ray C Boston

Journal article  |  2020  |  Clinical Neurophysiology

Objective To investigate the impact of sleep onset and offset on the rate of epileptiform discharges (ED) in idiopathic generalize..

Computer-assisted estimation of interictal discharge burden in idiopathic generalized epilepsy.

Dominique Eden, Ewan S Nurse, Shannon Clarke, Philippa J Karoly, Udaya Seneviratne, Mark Cook, Dean R Freestone, Wendyl D'Souza

Journal article  |  2020  |  Epilepsy & Behavior

Improved irritability, mood, and quality of life following introduction of perampanel as late adjunctive treatment for epilepsy

Johanna Sofia Moraes, Graham Hepworth, Sophia Ignatiadis, Anita Dharan, Ross Carne, Udaya Seneviratne, Mark J Cook, Wendyl Jude D'Souza

Journal article  |  2020  |  Epilepsy & Behavior

Quality of life and its association with comorbidities and adverse events from antiepileptic medications: Online survey of patients with epilepsy in Australia

Jeremy M Welton, Christine Walker, Kate Riney, Alvin Ng, Lisa Todd, Wendyl J D'Souza

Journal article  |  2020  |  Epilepsy & Behavior

Single-subject manual independent component analysis and resting state fMRI connectivity outcomes in patients with juvenile absence epilepsy

Nicholas Parsons, Stephen C Bowden, Simon Vogrin, Wendyl J D'Souza

Journal article  |  2020  |  Magnetic Resonance Imaging

The quality of fMRI data impacts functional connectivity measures and consequently, the decisions that clinicians and researchers ..