Paul Baird

Genome-wide association meta-analysis of corneal curvature identifies novel loci and shared genetic influences across axial length and refractive error

Qiao Fan, Alfred Pozarickij, Nicholas YQ Tan, Xiaobo Guo, Virginie JM Verhoeven, Veronique Vitart, Jeremy A Guggenheim, Masahiro Miyake, J Willem L Tideman, Anthony P Khawaja, Liang Zhang, Stuart MacGregor, Rene Hoehn, Peng Chen, Ginevra Biino, Juho Wedenoja, Seyed Ehsan Saffari, Milly S Tedja, Jing Xie, Carla Lanca, et al.

Journal article  |  2020  |  Communications Biology

Corneal curvature, a highly heritable trait, is a key clinical endophenotype for myopia - a major cause of visual impairment and b..

Association of Genetic Variation With Keratoconus

Bennet J McComish, Srujana Sahebjada, Yelena Bykhovskaya, Colin E Willoughby, Andrea J Richardson, Abi Tenen, Jac C Charlesworth, Stuart MacGregor, Paul Mitchell, Sionne EM Lucas, Richard A Mills, David A Mackey, Xiaohui Li, Jie Jin Wang, Richard A Jensen, Jerome I Rotter, Kent D Taylor, Alex W Hewitt, Yaron S Rabinowitz, Paul N Baird, et al.

Journal article  |  2020  |  JAMA Ophthalmology

Importance: Keratoconus is a condition in which the cornea progressively thins and protrudes in a conical shape, severely affectin..

Do age-related macular degeneration genes show association with keratoconus?

Ke Cao, Srujana Sahebjada, Andrea J Richardson, Paul N Baird

Journal article  |  2019  |  Eye and Vision

Pathway Analysis Integrating Genome-Wide and Functional Data Identifies PLCG2 as a Candidate Gene for Age-Related Macular Degeneration

Andrea R Waksmunski, Michelle Grunin, Tyler G Kinzy, Robert P Igo, Jonathan L Haines, Jessica N Cooke Bailey, Lars G Fritsche, Wilmar Igl, Felix Grassmann, Sebanti Sengupta, Jennifer L Bragg-Gresham, Kathryn P Burdon, Scott J Hebbring, Cindy Wen, Mathias Gorski, Ivana K Kim, David Cho, Donald Zack, Eric Souied, Hendrik PN Scholl, et al.

Journal article  |  2019  |  Investigative Opthalmology & Visual Science

Twin Registries Moving Forward and Meeting the Future: A Review

Paul N Baird, Pirro Hysi

Journal article  |  2019  |  Twin Research and Human Genetics

Assessment of clinical parameters by ethnicity in patients with keratoconus: a multi-country study

Srujana Sahebjada, Elsie Chan, Myra McGuinness, Christopher Hodge, Calvin CP Pang, Govindasamy Kumaramanickavel, Gerard Sutton, Mark Daniell, Paul N Baird

Conference Proceedings  |  2019  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Genome-wide association study on a large multi-ethnic sample identifies new genetic loci that predispose to keratoconus

Alison J Hardcastle, Pirro G Hysi, Karla Rojas-Lopez, Petra Liskova, Alice E Davidson, Manir Ali, Kathryn P Burdon, David O'Brart, Chris Inglehearn, Paul N Baird, Christopher J Hammond, Stephen J Tuft

Conference Proceedings  |  2019  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Ranking the importance of genetic factors by variable-selection confidence sets

Chao Zheng, Davide Ferrari, Michael Zhang, Paul Baird

Journal article  |  2019  |  Journal of the Royal Statistical Society: Series C (Applied Statistics)

IMI - Myopia Genetics Report

Milly S Tedja, Annechien EG Haarman, Magda A Meester-Smoor, Jaakko Kaprio, David A Mackey, Jeremy A Guggenheim, Christopher J Hammond, Virginie JM Verhoeven, Caroline CW Klaver, Joan E Bailey-Wilson, Paul Nigel Baird, Amutha Barathi Veluchamy, Ginevra Biino, Kathryn P Burdon, Harry Campbell, Li Jia Chen, Ching-Yu Cheng, Emily Y Chew, Jamie E Craig, Phillippa M Cumberland, et al.

Journal article  |  2019  |  Investigative Opthalmology & Visual Science

Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases (vol 9, 1864, 2018)

Adriana I Iglesias, Aniket Mishra, Veronique Vitart, Yelena Bykhovskaya, Rene Hoehn, Henriet Springelkamp, Gabriel Cuellar-Partida, Puya Gharahkhani, Jessica N Cooke Bailey, Colin E Willoughby, Xiaohui Li, Seyhan Yazar, Abhishek Nag, Anthony P Khawaja, Ozren Polasek, David Siscovick, Paul Mitchell, Yih Chung Tham, Jonathan L Haines, Lisa S Kearns, et al.

Journal article  |  2019  |  Nature Communications

Association of Genetic Variants With Response to Anti-Vascular Endothelial Growth Factor Therapy in Age-Related Macular Degeneration

Laura Lores-Motta, Moeen Riaz, Michelle Grunin, Jordi Corominas, Freekje van Asten, Marc Pauper, Mathieu Leenders, Andrea J Richardson, Philipp Muether, Angela J Cree, Helen L Griffiths, Connie Pham, Marie-Claude Belanger, Magda A Meester-Smoor, Manir Ali, Iris M Heid, Lars G Fritsche, Usha Chakravarthy, Richard Gale, Martin McKibbin, et al.

Journal article  |  2018  |  JAMA Ophthalmology

Economic impact of Keratoconus -a patient's perspective

Srujana Sahebjada, Elsie Chan, Sara Vogrin, Vijaya Sundararajan, Mark Daniell, Paul N Baird

Conference Proceedings  |  2018  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

A genome-wide association study for keratoconus identifies novel risk loci

Kathryn P Burdon, Bennet McComish, Paul N Baird, Yelena Bykhovskaya, Andrea Richardson-Wynd, Colin E Willoughby, Xiaohui Li, Srujana Sahebjada, Stuart MacGregor, Sionne Lucas, Jerome I Rotter, Richard A Mills, Alex W Hewitt, Yaron Rabinowitz, Jamie E Craig

Conference Proceedings  |  2018  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error

Milly S Tedja, Robert Wojciechowski, Pirro G Hysi, Nicholas Eriksson, Nicholas A Furlotte, Virginie JM Verhoeven, Adriana I Iglesias, Magda A Meester-Smoor, Stuart W Tompson, Qiao Fan, Anthony P Khawaja, Ching-Yu Cheng, Rene Hoehn, Kenji Yamashiro, Adam Wenocur, Clare Grazal, Toomas Haller, Andres Metspalu, Juho Wedenoja, Jost B Jonas, et al.

Journal article  |  2018  |  Nature Genetics

Recurrent structural variation, clustered sites of selection, and disease risk for the complement factor H (CFH) gene family

Stuart Cantsilieris, Bradley J Nelson, John Huddleston, Carl Baker, Lana Harshman, Kelsi Penewit, Katherine M Munson, Melanie Sorensen, AnneMarie E Welch, Vy Dang, Felix Grassmann, Andrea J Richardson, Robyn H Guymer, Tina A Graves-Lindsay, Richard K Wilson, Bernhard HF Weber, Paul N Baird, Rando Allikmets, Evan E Eichler

Journal article  |  2018  |  Proceedings of the National Academy of Sciences

Changing vision: a review of pharmacogenetic studies for treatment response in age-related macular degeneration patients

Janan Arslan, Paul N Baird

Journal article  |  2018  |  Pharmacogenomics

Establishment and activity of the Asian Eye Genetics Consortium (AEGC)

Takeshi Iwata, Gyan Prakash, Paul Baird, S Natarajan

Conference Proceedings  |  2018  |  HUMAN GENOMICS

Gene Expression and Pathways Underlying Form Deprivation Myopia in the Guinea Pig Sclera

Nethrajeith Srinivasalu, Sally A McFadden, Callan Medcalf, Lena Fuchs, Jessica Chung, Gayle Philip, Andrea Richardson, Moeen Riaz, Paul N Baird

Journal article  |  2018  |  Investigative Opthalmology & Visual Science

A genome-wide association study of corneal astigmatism: The CREAM Consortium

Rupal L Shah, Qing Li, Wanting Zhao, Milly S Tedja, J Willem L Tideman, Anthony P Khawaja, Qiao Fan, Seyhan Yazar, Katie M Williams, Virginie JM Verhoeven, Jing Xie, Ya Xing Wang, Moritz Hess, Stefan Nickels, Karl J Lackner, Olavi Parssinen, Juho Wedenoja, Ginevra Biino, Maria Pina Concas, Andre Uitterlinden, et al.

Journal article  |  2018  |  Molecular Vision

A decade of age-related macular degeneration risk models: What have we learned from them and where are we going?

Michael Zhang, Paul N Baird

Journal article  |  2017  |  Ophthalmic Genetics

Loss of Function of P2X7 Receptor Scavenger Activity in Aging Mice A Novel Model for Investigating the Early Pathogenesis of Age-Related Macular Degeneration

Kirstan A Vessey, Ben J Gu, Andrew I Jobling, Joanna A Phipps, Ursula Greferath, Mai X Tran, Michael A Dixon, Paul N Baird, Robyn H Guymer, James S Wiley, Erica L Fletcher

Journal article  |  2017  |  The American Journal of Pathology

Joint Analysis of Nuclear and Mitochondrial Variants in Age-Related Macular Degeneration Identifies Novel Loci TRPM1 and ABHD2/RLBP1

Patrice J Persad, Iris M Heid, Daniel E Weeks, Paul N Baird, Eiko K de Jong, Jonathan L Haines, Margaret A Pericak-Vance, William K Scott

Journal article  |  2017  |  Investigative Opthalmology & Visual Science

International networks in eye disease - the Asian Eye Genetics Consortium (AEGC)

Takeshi Iwata, Gyan Prakash, Paul N Baird, S Natarajan

Conference Proceedings  |  2017  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Whole Exome sequencing to identify the pharmacogenetic basis of retinal fluid clearance in anti-VEGF treated AMD

Paul N Baird, Moeen Riaz, Andrea J Richardson, Nguyen Thanh, Shilpa Taori, Chiea Chuen Khor, Robyn H Guymer

Conference Proceedings  |  2017  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Identification of a Novel Variant Associated with anti-VEGF Response in Age-related Macular Degeneration Using Exome Chip Analysis

Michelle Grunin, Laura Lores-Motta, Moeen Riaz, Jordi Corominas, Andrea J Richardson, Sascha Fauser, Robyn H Guymer, Eiko de Jong, Iris M Heid, Carel CB Hoyng, Andrew J Lotery, Paul Mitchell, Paul N Baird, Anneke I Den Hollander, Itay Chowers

Conference Proceedings  |  2017  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Recent advances and future directions for the pharmacogenetic basis of anti-VEGF treatment response in neovascular age-related macular degeneration

Moeen Riaz, Paul N Baird

Journal article  |  2017  |  Neural Regeneration Research

GWAS study using DNA pooling strategy identifies association of variant rs4910623 in OR52B4 gene with anti-VEGF treatment response in age-related macular degeneration

Moeen Riaz, Laura Lores-Motta, Andrea J Richardson, Yi Lu, Grant Montgomery, Amer Omar, Robert K Koenekoop, John Chen, Philipp Muether, Lebriz Altay, Tina Schick, Sascha Fauser, Dzenita Smailhodzic, Freekje van Asten, Eiko K de Jong, Carel B Hoyng, Kathryn P Burdon, Stuart MacGregor, Robyn H Guymer, Anneke I den Hollander, et al.

Journal article  |  2016  |  Scientific Reports

Pooled genome wide association detects association upstream of FCRL3 with Graves' disease

Jwu Jin Khong, Kathryn P Burdon, Yi Lu, Kate Laurie, Lefta Leonardos, Paul N Baird, Srujana Sahebjada, John P Walsh, Adam Gajdatsy, Peter R Ebeling, Peter Shane Hamblin, Rosemary Wong, Simon P Forehan, Spiros Fourlanos, Anthony P Roberts, Matthew Doogue, Dinesh Selva, Grant W Montgomery, Stuart Macgregor, Jamie E Craig

Journal article  |  2016  |  BMC Genomics

Childhood gene-environment interactions and age-dependent effects of genetic variants associated with refractive error and myopia: The CREAM Consortium

Qiao Fan, Xiaobo Guo, J Willem L Tideman, Katie M Williams, Seyhan Yazar, S Mohsen Hosseini, Laura D Howe, Beate St Pourcain, David M Evans, Nicholas J Timpson, George McMahon, Pirro G Hysi, Eva Krapohl, Ya Xing Wang, Jost B Jonas, Paul Nigel Baird, Jie Jin Wang, Ching-Yu Cheng, Yik-Ying Teo, Tien-Yin Wong, et al.

Journal article  |  2016  |  Scientific Reports

Multiallelic copy number variation in the complement component 4A (C4A) gene is associated with late-stage age-related macular degeneration (AMD)

Felix Grassmann, Stuart Cantsilieris, Anja-Sabrina Schulz-Kuhnt, Stefan J White, Andrea J Richardson, Alex W Hewitt, Brendan J Vote, Denise Schmied, Robyn H Guymer, Bernhard HF Weber, Paul N Baird

Journal article  |  2016  |  Journal of Neuroinflammation

Meta-analysis of gene-environment-wide association scans accounting for education level identifies additional loci for refractive error

Qiao Fan, Virginie JM Verhoeven, Robert Wojciechowski, Veluchamy A Barathi, Pirro G Hysi, Jeremy A Guggenheim, Rene Hoehn, Veronique Vitart, Anthony P Khawaja, Kenji Yamashiro, S Mohsen Hosseini, Terho Lehtimaki, Yi Lu, Toomas Haller, Jing Xie, Cecile Delcourt, Mario Pirastu, Juho Wedenoja, Puya Gharahkhani, Cristina Venturini, et al.

Journal article  |  2016  |  Nature Communications

Reticular Pseudodrusen and Their Association with Age-Related Macular Degeneration

Robert P Finger, Elaine Chong, Myra B McGuinness, Luba D Robman, Khin Zaw Aung, Graham Giles, Paul N Baird, Robyn H Guymer

Journal article  |  2016  |  Ophthalmology

Reticular Pseudodrusen in Intermediate Age-Related Macular Degeneration: Prevalence, Detection, Clinical, Environmental, and Genetic Associations

Zhichao Wu, Lauren N Ayton, Chi D Luu, Paul N Baird, Robyn H Guymer

Journal article  |  2016  |  Investigative Opthalmology & Visual Science

A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants

Lars G Fritsche, Wilmar Igl, Jessica N Cooke Bailey, Felix Grassmann, Sebanti Sengupta, Jennifer L Bragg-Gresham, Kathryn P Burdon, Scott J Hebbring, Cindy Wen, Mathias Gorski, Ivana K Kim, David Cho, Donald Zack, Eric Souied, Hendrik PN Scholl, Elisa Bala, Kristine E Lee, David J Hunter, Rebecca J Sardell, Paul Mitchell, et al.

Journal article  |  2016  |  Nature Genetics

Genetics in Retinal Diseases

Moeen Riaz, Paul N Baird

Journal article  |  2016  |  Developments in Ophthalmology

Association Study of Mannose-Binding Lectin Levels and Genetic Variants in Lectin Pathway Proteins with Susceptibility to Age-Related Macular Degeneration: A Case-Control Study

Michael Osthoff, Melinda M Dean, Paul N Baird, Andrea J Richardson, Mark Daniell, Robyn H Guymer, Damon P Eisen

Journal article  |  2015  |  PLOS ONE

Genetic variation at the GPC6 gene is reproducibly associated with keratoconus in a genome-wide association study

Kathryn P Burdon, Yi Lu, Paul N Baird, Richard A Mills, Yelena Bykhovskaya, Srujana Sahebjada, Yaron S Rabinowitz, Xiaohui Li, Stuart MacGregor, Jamie E Craig

Conference Proceedings  |  2015  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

AGE-RELATED MACULAR DEGENERATION PHENOTYPES ASSOCIATED WITH MUTUALLY EXCLUSIVE HOMOZYGOUS RISK VARIANTS IN CFH AND HTRA1 GENES

Elaine W Chong, Fakir M Amirul Islam, Liubov D Robman, Khin Zaw Aung, Andrea J Richardson, Paul N Baird, Robyn H Guymer

Journal article  |  2015  |  Retina

Age-Related Macular Degeneration in Ethnically Diverse Australia: Melbourne Collaborative Cohort Study

Liubov D Robman, Fakir MA Islam, Elaine WT Chong, Madeleine KM Adams, Julie A Simpson, Khin Zaw Aung, Galina A Makeyeva, John L Hopper, Dallas R English, Graham G Giles, Paul N Baird, Robyn H Guymer

Journal article  |  2015  |  Ophthalmic Epidemiology

Identification of myopia-associated WNT7B polymorphisms provides insights into the mechanism underlying the development of myopia

Masahiro Miyake, Kenji Yamashiro, Yasuharu Tabara, Kenji Suda, Satoshi Morooka, Hideo Nakanishi, Chiea-Chuen Khor, Peng Chen, Fan Qiao, Isao Nakata, Yumiko Akagi-Kurashige, Norimoto Gotoh, Akitaka Tsujikawa, Akira Meguro, Sentaro Kusuhara, Ozen Polasek, Caroline Hayward, Alan F Wright, Harry Campbell, Andrea J Richardson, et al.

Journal article  |  2015  |  Nature Communications

Genome-wide association study for refractive astigmatism reveals genetic co-determination with spherical equivalent refractive error: the CREAM consortium

Qing Li, Robert Wojciechowski, Claire L Simpson, Pirro G Hysi, Virginie JM Verhoeven, Mohammad Kamran Ikram, Rene Hoehn, Veronique Vitart, Alex W Hewitt, Konrad Oexle, Kari-Matti Makela, Stuart MacGregor, Mario Pirastu, Qiao Fan, Ching-Yu Cheng, Beat St Pourcain, George McMahon, John P Kemp, Kate Northstone, Jugnoo S Rahi, et al.

Journal article  |  2015  |  Human Genetics

Assessment of Macular Parameter Changes in Patients with Keratoconus Using Optical Coherence Tomography

Srujana Sahebjada, Fakir M Amirul Islam, Sanj Wickremasinghe, Mark Daniell, Paul N Baird

Journal article  |  2015  |  Journal of Ophthalmology

POLYMORPHISMS IN THE APOE GENE AND THE LOCATION OF RETINAL FLUID IN EYES WITH NEOVASCULAR AGE-RELATED MACULAR DEGENERATION

Sanjeewa S Wickremasinghe, Sukhpal S Sandhu, Fakir M Amirul-Islam, Farshad Abedi, Andrea J Richardson, Paul N Baird, Robyn H Guymer

Journal article  |  2014  |  Retina

Genome-wide analysis of multi-ancestry cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma

Pirro G Hysi, Ching-Yu Cheng, Henriet Springelkamp, Stuart Macgregor, Jessica N Cooke Bailey, Robert Wojciechowski, Veronique Vitart, Abhishek Nag, Alex W Hewitt, Rene Hohn, Cristina Venturini, Alireza Mirshahi, Wishal D Ramdas, Gudmar Thorleifsson, Eranga Vithana, Chiea-Chuen Khor, Arni B Stefansson, Jiemin Liao, Jonathan L Haines, Najaf Amin, et al.

Journal article  |  2014  |  Nature Genetics

Genome-Wide Meta-Analysis of Myopia and Hyperopia Provides Evidence for Replication of 11 Loci

Claire L Simpson, Robert Wojciechowski, Konrad Oexle, Federico Murgia, Laura Portas, Xiaohui Li, Virginie JM Verhoeven, Veronique Vitart, Maria Schache, S Mohsen Hosseini, Pirro G Hysi, Leslie J Raffel, Mary Frances Cotch, Emily Chew, Barbara EK Klein, Ronald Klein, Tien Yin Wong, Cornelia M Van Duijn, Paul Mitchell, Seang Mei Saw, et al.

Journal article  |  2014  |  PLoS ONE

The role of proteases and inflammatory molecules in triggering neovascular age-related macular degeneration: basic science to clinical relevance

Sivaraman A Balasubramanian, Kaavya Krishna Kumar, Paul N Baird

Journal article  |  2014  |  Translational Research

Meta-analysis of genome-wide association studies identifies novel loci that influence cupping and the glaucomatous process

Henriet Springelkamp, Rene Hoehn, Aniket Mishra, Pirro G Hysi, Chiea-Chuen Khor, Stephanie J Loomis, Jessica N Cooke Bailey, Jane Gibson, Gudmar Thorleifsson, Sarah F Janssen, Xiaoyan Luo, Wishal D Ramdas, Eranga Vithana, Monisha E Nongpiur, GrantW Montgomery, Liang Xu, Jenny E Mountain, Puya Gharahkhani, Yi Lu, Najaf Amin, et al.

Journal article  |  2014  |  Nature Communications

Dietary Patterns and Their Associations with Age-Related Macular Degeneration

Fakir M Amirul Islam, Elaine W Chong, Allison M Hodge, Robyn H Guymer, Khin Zaw Aung, Galina A Makeyeva, Paul N Baird, John L Hopper, Dallas R English, Graham G Giles, Liubov D Robman

Journal article  |  2014  |  Ophthalmology

Assessment of Anterior Segment Parameters of Keratoconus Eyes in an Australian Population

Srujana Sahebjada, Jing Xie, Elsie Chan, Grant Snibson, Mark Daniel, Paul N Baird

Journal article  |  2014  |  Optometry and Vision Science

Technical considerations for genotyping multi-allelic copy number variation (CNV), in regions of segmental duplication

Stuart Cantsilieris, Patrick S Western, Paul N Baird, Stefan J White

Journal article  |  2014  |  BMC Genomics

Identification of independent associations involving HLA Class II loci and Age-Related Macular Degeneration (AMD)

Paul N Baird, Andrea J Richardson, Robyn H Guymer

Conference Proceedings  |  2014  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Association of the Hepatocyte Growth Factor Gene with Keratoconus in an Australian Population

Srujana Sahebjada, Maria Schache, Andrea J Richardson, Grant Snibson, Mark Daniell, Paul N Baird

Journal article  |  2014  |  PLoS One

How genetic studies have advanced our understanding of age-related macular degeneration and their impact on patient care: a review

Paul N Baird, Subhabrata Chakrabarti

Journal article  |  2014  |  Clinical & Experimental Ophthalmology

Predictors of anti-VEGF treatment response in neovascular age-related macular degeneration

Robert P Finger, Sanjeewa S Wickremasinghe, Paul N Baird, Robyn H Guymer

Journal article  |  2014  |  Survey of Ophthalmology

Impact of Keratoconus in the Better Eye and the Worse Eye on Vision-Related Quality of Life

Srujana Sahebjada, Eva K Fenwick, Jing Xie, Grant R Snibson, Mark D Daniell, Paul N Baird

Journal article  |  2014  |  Investigative Ophthalmology and Visual Science

Proof of Concept, Randomized, Placebo-Controlled Study of the Effect of Simvastatin on the Course of Age-Related Macular Degeneration

Robyn H Guymer, Paul N Baird, Mary Varsamidis, Lucy Busija, Peter N Dimitrov, Khin Zaw Aung, Galina A Makeyeva, Andrea J Richardson, Lyndell Lim, Liubov D Robman

Journal article  |  2013  |  PLoS One

Evaluating the Association Between Keratoconus and the Corneal Thickness Genes in an Independent Australian Population

Srujana Sahebjada, Maria Schache, Andrea J Richardson, Grant Snibson, Stuart MacGregor, Mark Daniell, Paul N Baird

Journal article  |  2013  |  Investigative Ophthalmology and Visual Science

Germline Variants and Advanced Colorectal Adenomas: Adenoma Prevention with Celecoxib Trial Genome-wide Association Study

Jiping Wang, Luis G Carvajal-Carmona, Jen-Hwa Chu, Ann G Zauber, Michikai Kubo, Koichi Matsuda, Malcolm Dunlop, Richard S Houlston, Oliver Sieber, Lara Lipton, Peter Gibbs, Nicholas G Martin, Grant W Montgomery, Joanne Young, Paul N Baird, Mark J Ratain, Yusuke Nakamura, Scott T Weiss, Ian Tomlinson, Monica M Bertagnolli

Journal article  |  2013  |  Clinical Cancer Research

Identification of a rare coding variant in complement 3 associated with age-related macular degeneration

Xiaowei Zhan, David E Larson, Chaolong Wang, Daniel C Koboldt, Yuri V Sergeev, Robert S Fulton, Lucinda L Fulton, Catrina C Fronick, Kari E Branham, Jennifer Bragg-Gresham, Goo Jun, Youna Hu, Hyun Min Kang, Dajiang Liu, Mohammad Othman, Matthew Brooks, Rinki Ratnapriya, Alexis Boleda, Felix Grassmann, Claudia von Strachwitz, et al.

Journal article  |  2013  |  Nature Genetics

Nine Loci for Ocular Axial Length Identified through Genome-wide Association Studies, Including Shared Loci with Refractive Error

Ching-Yu Cheng, Maria Schache, M Kamran Ikram, Terri L Young, Jeremy A Guggenheim, Veronique Vitart, Stuart MacGregor, Virginie JM Verhoeven, Veluchamy A Barathi, Jiemin Liao, Pirro G Hysi, Joan E Bailey-Wilson, Beate St Pourcain, John P Kemp, George McMahon, Nicholas J Timpson, David M Evans, Grant W Montgomery, Aniket Mishra, Ya Xing Wang, et al.

Journal article  |  2013  |  American Journal of Human Genetics

Genetic Influences on the Outcome of Anti-Vascular Endothelial Growth Factor Treatment in Neovascular Age-related Macular Degeneration

Farshad Abedi, Sanjeewa Wickremasinghe, Andrea J Richardson, Amirul FM Islam, Robyn H Guymer, Paul N Baird

Journal article  |  2013  |  Ophthalmology

Meta-analysis of genome-wide association studies in five cohorts reveals common variants in RBFOX1, a regulator of tissue-specific splicing, associated with refractive error

Dwight Stambolian, Robert Wojciechowski, Konrad Oexle, Mario Pirastu, Xiaohui Li, Leslie J Raffel, Mary Frances Cotch, Emily Y Chew, Barbara Klein, Ronald Klein, Tien Y Wong, Claire L Simpson, Caroline CW Klaver, Cornelia M van Duijn, Virginie JM Verhoeven, Paul N Baird, Veronique Vitart, Andrew D Paterson, Paul Mitchell, Seang Mei Saw, et al.

Journal article  |  2013  |  Human Molecular Genetics

Genetic Loci for Retinal Arteriolar Microcirculation

Xueling Sim, Richard A Jensen, M Kamran Ikram, Mary Frances Cotch, Xiaohui Li, Stuart MacGregor, Jing Xie, Albert Vernon Smith, Eric Boerwinkle, Paul Mitchell, Ronald Klein, Barbara EK Klein, Nicole L Glazer, Thomas Lumley, Barbara McKnight, Bruce M Psaty, Paulus TVM de Jong, Albert Hofman, Fernando Rivadeneira, Andre G Uitterlinden, et al.

Journal article  |  2013  |  PLoS One

Age-related macular degeneration and DNA methylation

Paul N Baird, Lai Wei

Journal article  |  2013  |  Epigenomics

Data-Driven Pattern Analysis of Dietary Items in Relation to Age-Related Macular Degeneration

Amirul Islam, Elaine Chong, Allison Hodge, Robyn Guymer, Khin Zaw Aung, Galina Makeyeva, Dallas English, Graham Giles, Paul Baird, Liubov Robman

Conference Proceedings  |  2013  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Ethnic disparity in prevalence of retinal vein occlusions amongst older Australians - the Melbourne Collaborative Cohort Study

Khin Zaw Aung, Galina Makeyeva, Madeleine Adams, Elaine Chong, Paul Baird, Robyn Guymer, Liubov Robman

Conference Proceedings  |  2013  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Association studies of EGR-1, PCDHB9, NARF, OGDH and SELENBP1 with myopia and myopia sub phenotypes reveals a novel association of OGDH with corneal curvature

Paul Baird, Maria Schache

Conference Proceedings  |  2013  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

The Consortium for Refractive Error and Myopia (CREAM) Identifies Four New Loci for Ocular Axial Length and Demonstrates Shared Loci for Axial Length and Refractive Error through Genome-Wide Association Studies

Ching-Yu Cheng, Maria Schache, Mohammad Ikram, Jeremy Guggenheim, Dwight Stambolian, Caroline Klaver, Yik-Ying Teo, Seang-Mei Saw, Paul Baird

Conference Proceedings  |  2013  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Younger Siblings, C-Reactive Protein, and Risk of Age-Related Macular Degeneration

Amy C Cohn, Lucy Busija, Liubov D Robman, Peter N Dimitrov, Mary Varsamidis, Lyndell L Lim, Paul N Baird, Robyn H Guymer

Journal article  |  2013  |  American Journal of Epidemiology

THE PREVALENCE AND RISK FACTORS OF EPIRETINAL MEMBRANES The Melbourne Collaborative Cohort Study

Khin Z Aung, Galina Makeyeva, Madeleine K Adams, Elaine W-T Chong, Lucy Busija, Graham G Giles, Dallas R English, John Hopper, Paul N Baird, Robyn H Guymer, Liubov D Robman

Journal article  |  2013  |  Retina: the journal of retinal and vitreous diseases

Association of the del443ins54 at the ARMS2 locus in Indian and Australian cohorts with age-related macular degeneration

Inderjeet Kaur, Stuart Cantsilieris, Saritha Katta, Andrea J Richardson, Maria Schache, Rajeev R Pappuru, Raja Narayanan, Annie Mathai, Ajit B Majji, Nicole Tindill, Robyn H Guymer, Subhabrata Chakrabarti, Paul N Baird

Journal article  |  2013  |  Molecular Vision

A rare functional haplotype of the P2RX4 and P2RX7 genes leads to loss of innate phagocytosis and confers increased risk of age-related macular degeneration

Ben J Gu, Paul N Baird, Kirstan A Vessey, Kristen K Skarratt, Erica L Fletcher, Stephen J Fuller, Andrea J Richardson, Robyn H Guymer, James S Wiley

Journal article  |  2013  |  FASEB Journal

Seven new loci associated with age-related macular degeneration

Lars G Fritsche, Wei Chen, Matthew Schu, Brian L Yaspan, Yi Yu, Gudmar Thorleifsson, Donald J Zack, Satoshi Arakawa, Valentina Cipriani, Stephan Ripke, Robert P Igo, Gabrielle HS Buitendijk, Xueling Sim, Daniel E Weeks, Robyn H Guymer, Joanna E Merriam, Peter J Francis, Gregory Hannum, Anita Agarwal, Ana Maria Armbrecht, et al.

Journal article  |  2013  |  Nature Genetics

Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia

Virginie JM Verhoeven, Pirro G Hysi, Robert Wojciechowski, Qiao Fan, Jeremy A Guggenheim, Rene Hoehn, Stuart MacGregor, Alex W Hewitt, Abhishek Nag, Ching-Yu Cheng, Ekaterina Yonova-Doing, Xin Zhou, M Kamran Ikram, Gabrielle HS Buitendijk, George McMahon, John P Kemp, Beate St Pourcain, Claire L Simpson, Karl-Matti Makela, Terho Lehtimaki, et al.

Journal article  |  2013  |  Nature Genetics

Genome-Wide Association Study of Retinopathy in Individuals without Diabetes

Richard A Jensen, Xueling Sim, Xiaohui Li, Mary Frances Cotch, M Kamran Ikram, Elizabeth G Holliday, Gudny Eiriksdottir, Tamara B Harris, Fridbert Jonasson, Barbara EK Klein, Lenore J Launer, Albert Vernon Smith, Eric Boerwinkle, Ning Cheung, Alex W Hewitt, Gerald Liew, Paul Mitchell, Jie Jin Wang, John Attia, Rodney Scott, et al.

Journal article  |  2013  |  PLoS One

Molecular methods for genotyping complex copy number polymorphisms

Stuart Cantsilieris, Paul N Baird, Stefan J White

Journal article  |  2013  |  Genomics

Genetic Association of Refractive Error and Axial Length with 15q14 but Not 15q25 in the Blue Mountains Eye Study Cohort

Maria Schache, Andrea J Richardson, Paul Mitchell, Jie Jin Wang, Elena Rochtchina, Ananth C Viswanathan, Tien Y Wong, Seang Mei Saw, Fotis Topouzis, Jing Xie, Xueling Sim, Elizabeth C Holliday, John Attia, Rodney J Scott, Paul N Baird

Journal article  |  2013  |  Ophthalmology

The Australian Twin Registry as a Resource For Genetic Studies into Ophthalmic Traits

Maria Schache, Paul N Baird

Journal article  |  2013  |  Twin Research and Human Genetics

Insights into the Genetic Architecture of Early Stage Age-Related Macular Degeneration: A Genome-Wide Association Study Meta-Analysis

Elizabeth G Holliday, Albert V Smith, Belinda K Cornes, Gabrielle HS Buitendijk, Richard A Jensen, Xueling Sim, Thor Aspelund, Tin Aung, Paul N Baird, Eric Boerwinkle, Ching Yu Cheng, Cornelia M van Duijn, Gudny Eiriksdottir, Vilmundur Gudnason, Tamara Harris, Alex W Hewitt, Michael Inouye, Fridbert Jonasson, Barbara EK Klein, Lenore Launer, et al.

Journal article  |  2013  |  PLoS One

Variants in the VEGFA Gene and Treatment Outcome after Anti-VEGF Treatment for Neovascular Age-related Macular Degeneration

Farshad Abedi, Sanjeewa Wickremasinghe, Andrea J Richardson, Enes Makalic, Daniel F Schmidt, Sukhpal S Sandhu, Paul N Baird, Robyn H Guymer

Journal article  |  2013  |  Ophthalmology

YOUNGER SIBLINGS, C-REACTIVE PROTEIN AND RISK OF AGE-RELATED MACULAR DEGENERATION

Luba Robman, Amy Cohn, Lucy Busija, Peter Dimitrov, Mary Varsamidis, Lyndell Lim, Paul Baird, Robyn Guymer

Conference Proceedings  |  2012  |  CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Can genetic associations change with age? CFH and age-related macular degeneration

Madeleine KM Adams, Julie A Simpson, Andrea J Richardson, Robyn H Guymer, Elizabeth Williamson, Stuart Cantsilieris, Dallas R English, Khin Zaw Aung, Galina A Makeyeva, Graham G Giles, John Hopper, Liubov D Robman, Paul N Baird

Journal article  |  2012  |  Human Molecular Genetics

VARIANTS IN THE HTRA1 AND ARMS2 GENES AND OUTCOME OF ANTI-VEGF TREATMENT IN NEOVASCULAR AMD

Farshad Abedi, Sanjeewa Wickremasinghe, Andrea J Richardson, Fakir A Islam, Robyn H Guymer, Paul N Baird

Conference Proceedings  |  2012  |  CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

POLYMORPHISMS OF THE APOE GENE AND THE QUALITATIVE OCT APPEARANCE IN EYES WITH NEOVASCULAR AMD

Sanj Wickremasinghe, Sukpal Sandhu, Fakir Islam, Farshad Abedi, Paul Baird, Robyn Guymer

Conference Proceedings  |  2012  |  CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Hypomethylation of the IL17RC Promoter Associates with Age-Related Macular Degeneration

Lai Wei, Baoying Liu, Jingsheng Tuo, Defen Shen, Ping Chen, Zhiyu Li, Xunxian Liu, Jia Ni, Pradeep Dagur, H Nida Sen, Shayma Jawad, Diamond Ling, Stanley Park, Sagarika Chakrabarty, Catherine Meyerle, Elvira Agron, Frederick L Ferris, Emily Y Chew, J Philip McCoy, Emily Blum, et al.

Journal article  |  2012  |  Cell Reports

Assessment of the Association of Matrix Metalloproteinases with Myopia, Refractive Error and Ocular Biometric Measures in an Australian Cohort

Maria Schache, Paul N Baird

Journal article  |  2012  |  PLoS One

Heritability of the spatial distribution and peak density of macular pigment: a classical twin study

RE Hogg, EL Ong, M Chamberlain, M Dirani, PN Baird, RH Guymer, F Fitzke

Journal article  |  2012  |  Eye - London

Large scale international replication and meta-analysis study confirms association of the 15q14 locus with myopia. The CREAM consortium

Virginie JM Verhoeven, Pirro G Hysi, Seang-Mei Saw, Veronique Vitart, Alireza Mirshahi, Jeremy A Guggenheim, Mary Frances Cotch, Kenji Yamashiro, Paul N Baird, David A Mackey, Robert Wojciechowski, M Kamran Ikram, Alex W Hewitt, Priya Duggal, Sarayut Janmahasatian, Chiea-Chuen Khor, Qiao Fan, Xin Zhou, Terri L Young, E-Shyong Tai, et al.

Journal article  |  2012  |  Human Genetics

Heritability and Genome-Wide Association Study to Assess Genetic Differences between Advanced Age-related Macular Degeneration Subtypes

Lucia Sobrin, Stephan Ripke, Yi Yu, Jesen Fagerness, Tushar R Bhangale, Perciliz L Tan, Eric H Souied, Gabrielle HS Buitendijk, Joanna E Merriam, Andrea J Richardson, Soumya Raychaudhuri, Robyn Reynolds, Kimberly A Chin, Aaron Y Lee, Nicolas Leveziel, Donald J Zack, Peter Campochiaro, R Theodore Smith, Gaetano R Barile, Ruth E Hogg, et al.

Journal article  |  2012  |  Ophthalmology

20/20-Alcohol and Age-related Macular Degeneration: The Melbourne Collaborative Cohort Study

Madeleine KM Adams, Elaine W Chong, Elizabeth Williamson, Khin Zaw Aung, Galina A Makeyeva, Graham G Giles, Dallas R English, John Hopper, Robyn H Guymer, Paul N Baird, Liubov D Robman, Julie A Simpson

Journal article  |  2012  |  American Journal of Epidemiology

Comprehensive Analysis of Copy Number Variation of Genes at Chromosome 1 and 10 Loci Associated with Late Age Related Macular Degeneration

Stuart Cantsilieris, Stefan J White, Andrea J Richardson, Robyn H Guymer, Paul N Baird

Journal article  |  2012  |  PLoS One

Delay to Treatment and Visual Outcomes in Patients Treated With Anti-Vascular Endothelial Growth Factor for Age-Related Macular Degeneration

Jonathan H Lim, Sanjeewa S Wickremasinghe, Jing Xie, Devinder S Chauhan, Paul N Baird, Luba D Robman, Gregory Hageman, Robyn H Guymer

Journal article  |  2012  |  American Journal of Ophthalmology

Apolipoprotein E Gene Associations in Age-related Macular Degeneration

Madeleine KM Adams, Julie A Simpson, Andrea J Richardson, Dallas R English, Khin Zaw Aung, Galina A Makeyeva, Robyn H Guymer, Graham G Giles, John Hopper, Liubov D Robman, Paul N Baird

Journal article  |  2012  |  American Journal of Epidemiology

Refinement of the associations between risk of colorectal cancer and polymorphisms on chromosomes 1q41 and 12q13.13

Sarah L Spain, Luis G Carvajal-Carmona, Kimberley M Howarth, Angela M Jones, Zhan Su, Jean-Baptiste Cazier, Jennet Williams, Lauri A Aaltonen, Paul Pharoah, David J Kerr, Jeremy Cheadle, Li Li, Graham Casey, Pavel Vodicka, Oliver Sieber, Lara Lipton, Peter Gibbs, Nicholas G Martin, Grant W Montgomery, Joanne Young, et al.

Journal article  |  2012  |  Human Molecular Genetics

Hypomethylation of IL17RC Promoter Associates with Age-related Macular Degeneration

L Wei, B Liu, J Tuo, D Shen, P Chen, Z Li, X Liu, J Ni, P Dagur, HN Sen, S Jawad, D Ling, S Park, S Chakrabarty, C Meyerle, E Argron, FL Ferris, EY Chew, P McCoy, E Blum, et al.

Journal article  |  2012  |  Cell Reports

Evidence of association of APOE with age-related macular degeneration - a pooled analysis of 15 studies

Gareth J McKay, Chris C Patterson, Usha Chakravarthy, Shilpa Dasari, Caroline C Klaver, Johannes R Vingerling, Lintje Ho, Paulus TVM de Jong, Astrid E Fletcher, Ian S Young, Johan H Seland, Mati Rahu, Gisele Soubrane, Laura Tomazzoli, Fotis Topouzis, Jesus Vioque, Aroon D Hingorani, Reecha Sofat, Michael Dean, Julie Sawitzke, et al.

Journal article  |  2011  |  Human Mutation

Gene patents related to common diseases of the eye.

Srujana Sahebjada, Stuart Cantsileris, Paul N Baird

Journal article  |  2011  |  Recent Patents on DNA & Gene Sequences

Visual impairment and blindness impose substantial morbidity and premature mortality on the population. The direct costs for visio..

Almost total protection from age-related macular degeneration by haplotypes of the Regulators of Complement Activation

Joseph F Williamson, Craig A McLure, Robyn H Guymer, Paul N Baird, John Millman, Stuart Cantsilieris, Roger L Dawkins

Journal article  |  2011  |  Genomics

Common variants near FRK/COL10A1 and VEGFA are associated with advanced age-related macular degeneration

Yi Yu, Tushar R Bhangale, Jesen Fagerness, Stephan Ripke, Gudmar Thorleifsson, Perciliz L Tan, Eric H Souied, Andrea J Richardson, Joanna E Merriam, Gabrielle HS Buitendijk, Robyn Reynolds, Soumya Raychaudhuri, Kimberly A Chin, Lucia Sobrin, Evangelos Evangelou, Phil H Lee, Aaron Y Lee, Nicolas Leveziel, Donald J Zack, Betsy Campochiaro, et al.

Journal article  |  2011  |  Human Molecular Genetics

Clinical validation of a genetic model to estimate the risk of developing choroidal neovascular age-related macular degeneration.

Gregory S Hageman, Karen Gehrs, Serguei Lejnine, Aruna T Bansal, Margaret M Deangelis, Robyn H Guymer, Paul N Baird, Rando Allikmets, Cosmin Deciu, Paul Oeth, Lorah T Perlee

Journal article  |  2011  |  Human Genomics

Predictive tests for estimating the risk of developing late-stage neovascular age-related macular degeneration (AMD) are subject t..

Variations in Apolipoprotein E Frequency With Age in a Pooled Analysis of a Large Group of Older People

Gareth J McKay, Giuliana Silvestri, Usha Chakravarthy, Shilpa Dasari, Lars G Fritsche, Bernhard H Weber, Claudia N Keilhauer, Michael L Klein, Peter J Francis, Caroline C Klaver, Johannes R Vingerling, Lintje Ho, Paulus TDV De Jong, Michael Dean, Julie Sawitzke, Paul N Baird, Robyn H Guymer, Dwight Stambolian, Anton Orlin, Johanna M Seddon, et al.

Journal article  |  2011  |  American Journal of Epidemiology

Variants in the APOE Gene Are Associated with Improved Outcome after Anti-VEGF Treatment for Neovascular AMD

Sanjeewa S Wickremasinghe, Jing Xie, Jonathan Lim, Devinder S Chauhan, Luba Robman, Andrea J Richardson, Gregory Hageman, Paul N Baird, Robyn Guymer

Journal article  |  2011  |  Investigative Ophthalmology and Visual Science

Multiple Common Susceptibility Variants near BMP Pathway Loci GREM1, BMP4, and BMP2 Explain Part of the Missing Heritability of Colorectal Cancer

Ian PM Tomlinson, Luis G Carvajal-Carmona, Sara E Dobbins, Albert Tenesa, Angela M Jones, Kimberley Howarth, Claire Palles, Peter Broderick, Emma EM Jaeger, Susan Farrington, Annabelle Lewis, James GD Prendergast, Alan M Pittman, Evropi Theodoratou, Bianca Olver, Marion Walker, Steven Penegar, Ella Barclay, Nicola Whiffin, Lynn Martin, et al.

Journal article  |  2011  |  PLoS Genetics

Identification of Urinary Biomarkers for Age-Related Macular Degeneration

Robyn H Guymer, Lingwei W Tao, Jonathan K Goh, Danny Liew, Olga Ischenko, Liubov D Robman, KhinZaw Aung, Tania Cipriani, Melinda Cain, Andrea J Richardson, Paul N Baird, Robyn Langham

Journal article  |  2011  |  Investigative Ophthalmology and Visual Science

Abdominal Obesity and Age-related Macular Degeneration

Madeleine KM Adams, Julie A Simpson, Khin Zaw Aung, Galina A Makeyeva, Graham G Giles, Dallas R English, John Hopper, Robyn H Guymer, Paul N Baird, Liubov D Robman

Journal article  |  2011  |  American Journal of Epidemiology

Animal Models of Retinal Disease

Erica L Fletcher, Andrew I Jobling, Kirstan A Vissey, Chi Luu, Robyn H Guymer, Paul N Baird

Book Chapter  |  2011  |  Progress in Molecular Biology and Translational Science

Analysis of glutathione S-transferase Pi isoform (GSTP1) single-nucleotide polymorphisms and macular telangiectasia type 2.

Joshua A Szental, Paul N Baird, Andrea J Richardson, FM Amirul Islam, Hendrik PN Scholl, Peter Charbel Issa, Frank G Holz, Mark Gillies, Robyn H Guymer

Journal article  |  2010  |  International Ophthalmology Clinics

Recent imaging studies have suggested that macular pigment is decreased centrally in macular telangiectasia type 2 (MT2). The upta..

CHANGING GENETIC ASSOCIATIONS WITH AGE - APOE AND AGE RELATED MACULAR DEGENERATION

Madeleine Adams, Luba Robman, Khin Zaw Aung, Galina Makeyeva, Robyn Guymer, Paul Baird

Conference Proceedings  |  2010  |  CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

VARIANTS IN THE APOE GENE ARE ASSOCIATED WITH IMPROVED TREATMENT OUTCOME FOLLOWING ANTI-VEGF THERAPY FOR NEOVASCULAR AMD

Sanj Wickremasinghe, Jonathan Lim, Jing Xie, Devinder Chauhan, Luba Robman, Andrea Richardson, Gregory Hageman, Paul Baird

Conference Proceedings  |  2010  |  CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

NON-MYDRIATIC DIGITAL RETINAL PHOTOGRAPHY AS A GOOD SCREENING TEST FOR UNDIAGNOSED RETINAL PATHOLOGY

Luba Robman, Khin Zaw Aung, Galina Makeyeva, Madeleine Adams, Paul Baird, Robyn Guymer

Conference Proceedings  |  2010  |  CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

The GEnes in Myopia (GEM) study in understanding the aetiology of refractive errors

Paul N Baird, Maria Schaeche, Mohamed Dirani

Journal article  |  2010  |  Progress in Retinal and Eye Research

PREVALENCE OF RETINAL VASCULAR PATHOLOGY IN OLDER AUSTRALIANS OF MEDITERRANEAN OR ANGLO-CELTIC ORIGIN

Galina Makeyeva, Madeleine Adams, Khin Zaw Aung, Lucy Busija, Paul Baird, Robyn Guymer, Luba Robman

Conference Proceedings  |  2010  |  CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

An Intergenic Region between the tagSNP rs3793917 and rs11200638 in the HTRA1 Gene Indicates Association with Age- Related Macular Degeneration

Andrea J Richardson, FM Amirul Islam, Khin Zaw Aung, Robyn H Guymer, Paul N Baird

Journal article  |  2010  |  Investigative Ophthalmology and Visual Science

Long-term refractive outcomes and stability after excimer laser surgery for myopia

Mohamed Dirani, Terry Couper, Joanne Yau, Eng K Ang, FM Amirul Islam, Grant R Snibson, Rasik B Vajpayee, Paul N Baird

Journal article  |  2010  |  Journal of Cataract and Refractive Surgery

C-Reactive Protein Levels and Complement Factor H Polymorphism Interaction in Age-related Macular Degeneration and Its Progression

Luba Robman, Paul N Baird, Peter N Dimitrov, Andrea J Richardson, Robyn H Guymer

Journal article  |  2010  |  Ophthalmology

Discordant refraction in male monozygotic twins.

Mohamed Dirani, Maria Schache, Paul Nigel Baird

Journal article  |  2010  |  Journal of Pediatric Ophthalmology and Strabismus

As part of the Genes In Myopia (GEM) Study, the authors describe a pair of monozygotic twins who presented with discordant hyperme..

Role of the Hepatocyte Growth Factor Gene in Refractive Error

Sundar Veerappan, Kelly K Pertile, Amirul FM Islam, Maria Schaeche, Christine Y Chen, Paul Mitchell, Mohamed Dirani, Paul N Baird

Journal article  |  2010  |  Ophthalmology

Genetics of retinal disease

MK Adams, RH Guymer, PN Baird

Book Chapter  |  2010

Twins studies and myopia

M Schache, PN Baird

Book Chapter  |  2010

Twin studies and myopia

M Schache, PN Baird

Book Chapter  |  2010

The hepatocyte growth factor receptor (MET) gene is not associated with refractive error and ocular biometrics in a Caucasian population

M Schache, CY Chen, M Dirani, PN Baird

Journal article  |  2009  |  Molecular Vision

Mirror image congenital esotropia and concordant hypermetropia in identical twins

Mohamed Dirani, Maria Schache, Paul N Baird

Journal article  |  2009  |  European Journal of Ophthalmology

New era for personalized medicine: the diagnosis and management of age-related macular degeneration

Paul N Baird, Gregory S Hageman, Robyn H Guymer

Journal article  |  2009  |  Clinical and Experimental Ophthalmology

The SERPING1 gene and age-related macular degeneration

Rando Allikmets, Michael Dean, Gregory S Hageman, Paul N Baird, Caroline C Klaver, Arthur A Bergen, Bernhard H Weber

Journal article  |  2009  |  The Lancet

Amyloid precursor protein processing and retinal pathology in mouse models of Alzheimer's disease

R Michael Dutescu, Qiao-Xin Li, Jonathan Crowston, Colin L Masters, Paul N Baird, Janetta G Culvenor

Journal article  |  2009  |  Graefe's Archive for Clinical and Experimental Ophthalmology

Mislabelling of twin zygosities - the Genes in Myopia (GEM) twin study

Mohamed Dirani, Maria Schache, Paul N Baird

Journal article  |  2009  |  Clinical and Experimental Ophthalmology

The retinoic acid receptor alpha (RARA) gene is not associated with myopia, hypermetropia, and ocular biometric measures

S Veerappan, M Schaeche, KK Pertile, FMA Islam, CY Chen, P Mitchell, M Dirani, PN Baird

Journal article  |  2009  |  Molecular Vision

Outcomes of laser refractive surgery for myopia

Eng K Ang, Terry Couper, Mohamed Dirani, Rasik B Vajpayee, Paul N Baird

Journal article  |  2009  |  Journal of Cataract and Refractive Surgery

Fine mapping linkage analysis identifies a novel susceptibility locus for myopia on chromosome 2q37 adjacent to but not overlapping MYP12

Maria Schache, Christine Y Chen, Kelly Kathleen Pertile, Andrea Jane Richardson, Mohamed Dirani, Paul Mitchell, Paul Nigel Baird

Journal article  |  2009  |  Molecular Vision

Sorsby's Fundus Dystrophy: a case report to raise awareness of the disease and potential future treatments

Joshua A Szental, Colin A Harper, Paul N Baird, Kira Michalova, Robyn H Guymer

Journal article  |  2009  |  Clinical and Experimental Ophthalmology

Primary open angle glaucoma in subjects harbouring the predicted GLC1L haplotype reveals a normotensive phenotype

Justin C Sherwin, Alex W Hewitt, Sonya L Bennett, Paul N Baird, Jamie E Craig, David A Mackey

Journal article  |  2009  |  Clinical and Experimental Ophthalmology

The dot-and-fleck retinopathy of X linked Alport syndrome is independent of complement factor H (CFH) gene polymorphisms

J Liu, D Colville, YY Wang, PN Baird, RH Guymer, J Savige

Journal article  |  2009  |  British Journal of Ophthalmology

Analysis of Rare Variants in the Complement Component 2 (C2) and Factor B (BF) Genes Refine Association for Age-Related Macular Degeneration (AMD)

Andrea J Richardson, FM Amirul Islam, Robyn H Guymer, Paul N Baird

Journal article  |  2009  |  Investigative Ophthalmology and Visual Science

Gene-Environment Interactions and Aging Visual Function A Classical Twin Study

Ruth E Hogg, Peter N Dimitrov, Mohamed Dirani, Mary Varsamidis, Matthew D Chamberlain, Paul N Baird, Robyn H Guymer, Algis J Vingrys

Journal article  |  2009  |  Ophthalmology

Mirror image congenital esotropia and concordant hypermetropia in identical twins

M DIRANI, M SCHACHE, P BAIRD

Journal article  |  2009  |  European Journal of Ophthalmology

Recent patents relating to diagnostic advances in age related macular degeneration (AMD).

Stuart Cantsilieris, Maria Schache, M Luisa Ashdown, Paul N Baird

Journal article  |  2009  |  Recent Patents on DNA & Gene Sequences

Age Related Macular Degeneration (AMD) is a complex neurodegenerative disorder accounting for 50% of blind registrations in the we..

Androgen Receptor Repeat Length Polymorphism Associated with Male-to-Female Transsexualism

Lauren Hare, Pascal Bernard, Francisco J Sanchez, Paul N Baird, Eric Vilain, Trudy Kennedy, Vincent R Harley

Journal article  |  2009  |  Biological Psychiatry

Role of Genetic Factors in Lower- and Higher-Order Aberrations - The Genes in Myopia Twin Study

M Dirani, M Chamberlain, TA Couper, RH Guymer, PN Baird

Journal article  |  2009  |  Ophthalmic Research: journal for research in experimental and clinical ophthalmology

The Role of Birth Weight in Myopia - The Genes in Myopia Twin Study

M Dirani, FMA Islam, PN Baird

Journal article  |  2009  |  Ophthalmic Research: journal for research in experimental and clinical ophthalmology

Myopia: Recent Advances in Molecular Studies; Prevalence, Progression and Risk Factors; Emmetropization; Therapies; Optical Links; Peripheral Refraction; Sclera and Ocular Growth; Signalling Cascades; and Animal Models.

NA McBrien, TL Young, CP Pang, C Hammond, P Baird, SM Saw, IG Morgan, DO Mutti, KA Rose, J Wallman, A Gentle, CF Wildsoet, J Gwiazda, KL Schmid, E Smith, D Troilo, J Summers-Rada, TT Norton, F Schaeffel, P Megaw, et al.

Conference Proceedings  |  2008  |  Myopia

The 12th International Myopia Conference held in Queensland, Australia on July 8-11, 2008 included 11 separate symposia, each with..

Evidence of shared genes in refraction and axial length: The Genes in Myopia (GEM) twin study

Mohamed Dirani, Sri N Shekar, Paul N Baird

Journal article  |  2008  |  Investigative Ophthalmology and Visual Science

Adult-onset myopia: The Genes in Myopia (GEM) twin study

Mohamed Dirani, Sri N Shekar, Paul N Baird

Journal article  |  2008  |  Investigative Ophthalmology and Visual Science

Gene-environment interaction in progression of AMD: the CFH gene, smoking and exposure to chronic infection

Paul N Baird, Luba D Robman, Andrea J Richardson, Peter N Dimitrov, Gabriella Tikellis, Catherine A McCarty, Robyn H Guymer

Journal article  |  2008  |  Human Molecular Genetics

Dominant genetic effects on corneal astigmatism: The genes in myopia (GEM) twin study

Mohamed Dirani, Amirul Islam, Sri N Shekar, Paul N Baird

Journal article  |  2008  |  Investigative Ophthalmology and Visual Science

Novel sequence elements define ancestral haplotypes of the region encompassing complement factor H

Joseph F Williamson, Craig A McLure, Paul N Baird, Dean Mate, John Millman, Blair Lawley, M Luisa Ashdown, Peter J Keating, Roger L Dawkins

Journal article  |  2008  |  Human Immunology

Ancestral LOXL1 variants are associated with pseudoexfoliation in Caucasian Australians but with markedly lower penetrance than in Nordic people

Alex W Hewitt, Shiwani Sharma, Kathryn P Burdon, Jie Jin Wang, Paul N Baird, David P Dimasi, David A Mackey, Paul Mitchell, Jamie E Craig

Journal article  |  2008  |  Human Molecular Genetics

Myopia and personality: The genes in myopia (GEM) personality study

Robert van de Berg, Mohamed Dirani, Christine Y Chen, Nicholas Haslam, Paul N Baird

Journal article  |  2008  |  Investigative Ophthalmology and Visual Science

The role of educational attainment in refraction: The genes in myopia (GEM) twin study

Mohamed Dirani, Sri N Shekar, Paul N Baird

Journal article  |  2008  |  Investigative Ophthalmology and Visual Science

Can HMG Co-A reductase inhibitors ("statins") slow the progression of age-related macular degeneration? The Age-Related Maculopathy Statin Study (ARMSS)

Robyn H Guymer, Peter N Dimitrov, Mary Varsamidis, Lyndell L Lim, Paul N Baird, Algis J Vingrys, Luba Robman

Journal article  |  2008  |  Clinical Interventions in Aging

Myocilin mutations and their role in open-angle glaucoma

P BAIRD

Book Chapter  |  2008

Testing protocol and recruitment in the genes in myopia twin study

M Dirani, M Chamberlain, P Garoufalis, C Chen, RH Guymer, PN Baird

Journal article  |  2008  |  Ophthalmic Epidemiology

Body stature and myopia - The genes in myopia (GEM) twin study

Mohamed Dirani, Amirul Islam, Paul N Baird

Journal article  |  2008  |  Ophthalmic Epidemiology

Assessment of TGIF as a candidate gene for myopia

Kelly K Pertile, Maria Schaeche, FM Amirul Islam, Christine Y Chen, Mohamed Dirani, Paul Mitchell, Paul N Baird

Journal article  |  2008  |  Investigative Ophthalmology and Visual Science

A tag-single nucleotide polymorphisms approach to the vascular endothelial growth factor-A gene in age-related macular degeneration

Andrea J Richardson, FM Amirul Islam, Robyn H Guymer, Melinda Cain, Paul N Baird

Journal article  |  2007  |  Molecular Vision

Genetic mapping of myopia susceptibility loci

Maria Schaeche, Andrea J Richardson, Kelly K Pertile, Mohamed Dirani, Katrina Scurrah, Paul N Baird

Journal article  |  2007  |  Investigative Ophthalmology and Visual Science

Linkage replication of the MYP12 locus in common myopia

Christine Y Chen, Jim Stankovich, Katrina J Scurrah, Pam Garoufalis, Mohamed Dirani, Kelly K Pertile, Andrea J Richardson, Paul N Baird

Journal article  |  2007  |  Investigative Ophthalmology and Visual Science

Vision-related quality of life comparison for emmetropes, myopes after refractive surgery, and myopes wearing spectacles or contact lenses

Christine Y Chen, Jill E Keeffe, Pam Garoufalis, Fakir MA Islam, Mohamed Dirani, Terry A Couper, Hugh R Taylor, Paul N Baird

Journal article  |  2007  |  Journal of Refractive Surgery

Evaluation of accuracy in proband-reported family history and its determinants: The genes in myopia family study

Pam Garoufalis, Christine Y Chen, Amirul Islam, Mohamed Dirani, Kelly K Pertile, Andrea J Richardson, Terry A Couper, Hugh R Taylor, Paul N Baird

Journal article  |  2007  |  Optometry and Vision Science

Heritability and shared environment estimates for myopia and associated ocular biometric traits: the Genes in Myopia (GEM) family study

Christine Yi-Chin Chen, Katrina Jacqueline Scurrah, Jim Stankovich, Pam Garoufalis, Mohamed Dirani, Kelly Kathleen Pertile, Andrea Jane Richardson, Paul Mitchell, Paul Nigel Baird

Journal article  |  2007  |  Human Genetics

Analysis of the RDS/peripherin gene in age-related macular degeneration

Paul N Baird, Andrea Richardson, Amirul Islam

Journal article  |  2007  |  Clinical and Experimental Ophthalmology

Discordant unilateral myopia in adult monozygotic twins.

M DIRANI, M CHAMBERLAIN, P GAROUFALIS, CYC CHEN, R GUYMER, P BAIRD

Journal article  |  2007  |  Australian Orthoptic Journal

Heritability of refractive error and ocular biometrics: The Genes in Myopia (GEM) Twin Study

Mohamed Dirani, Matthew Chamberlain, Sri N Shekar, Amirul FM Islam, Pam Garoufalis, Christine Y Chen, Robyn H Guymer, Paul N Baird

Journal article  |  2006  |  Investigative Ophthalmology and Visual Science

Unraveling a complex genetic disease: Age-related macular degeneration

Matt Chamberlain, Paul Baird, Mohamed Dirani, Robyn Guymer

Journal article  |  2006  |  Survey of Ophthalmology

Analysis of the Y402H variant of the complement factor H gene in age-related macular degeneration

Paul N Baird, FM Amirul Islam, Andrea J Richardson, Melinda Cain, Nicola Hunt, Robyn Guymer

Journal article  |  2006  |  Investigative Ophthalmology and Visual Science

Refractive errors in twin studies

Mohamed Dirani, Matthew Chamberlain, Pam Garoufalis, Christine Chen, Robyn H Guymer, Paul N Baird

Journal article  |  2006  |  Twin Research

Concordant bilateral Duane's Retraction Syndrome (type 1) in female monozygotic twins

Mohamed Dirani, Matthew Chamberlain, Pam Garoufalis, Christine Chen, Robyn H Guymer, Paul N Baird

Journal article  |  2006  |  Clinical and Experimental Ophthalmology

Blood storage at 4 degrees C - factors involved in DNA yield and quality

Andrea J Richardson, Niro Narendran, Robyn H Guymer, Hien Vu, Paul N Baird

Journal article  |  2006  |  Journal of Laboratory & Clinical Medicine

Mirror-image congenital esotropia in monozygotic twins

M Dirani, M Chamberlain, P Garoufalis, CY Chen, RH Guymer, PN Baird

Journal article  |  2006  |  Journal of Pediatric Ophthalmology and Strabismus

Marked discordance for myopia in female monozygotic twins

M Dirani, M Chamberlain, P Garoufalis, C Chen, RH Guymer, PN Baird

Journal article  |  2006  |  Clinical and Experimental Ophthalmology

Apolipoprotein (APOE) gene is associated with progression of age-related macular degeneration (AMD)

PN Baird, AJ Richardson, LD Robman, PN Dimitrov, G Tikellis, CA McCarty, RH Guymer

Journal article  |  2006  |  Human Mutation

Heritability of macular thickness determined by optical coherence tomography

MD Chamberlain, RH Guymer, M Dirani, JL Hopper, PN Baird

Journal article  |  2006  |  Investigative Ophthalmology and Visual Science

Genes and age-related macular degeneration

RH Guymer, N Narendran, PN Baird

Book Chapter  |  2005

Methodology and recruitment of probands and their families for the Genes in Myopia (GEM) Study

P Garoufalis, CYC Chen, M Dirani, TA Couper, HR Taylor, PN Baird

Journal article  |  2005  |  Ophthalmic Epidemiology

A common disease haplotype for the Q368STOP mutation of the myocilin gene in Australian and Canadian glaucoma families

PN Baird, AJ Richardson, DA Mackey, JE Craig, M Faucher, V Raymond

Journal article  |  2005  |  American Journal of Ophthalmology

Linkage to 10q22 for maximum intraocular pressure and 1p32 for maximum cup-to-disc ratio in an extended primary open-angle glaucoma pedigree

JC Charlesworth, TD Dyer, JM Stankovich, J Blangero, DA Mackey, JE Craig, CM Green, SJ Foote, PN Baird, MM Sale

Journal article  |  2005  |  Investigative Ophthalmology and Visual Science

Evidence for a novel glaucoma locus at chromosome 3p21-22

PN Baird, SJ Foote, DA Mackey, J Craig, TP Speed, A Bureau

Journal article  |  2005  |  Human Genetics

The Q368STOP myocilin mutation in a population-based cohort: The Blue Mountains Eye Study

PN Baird, AJ Richardson, JE Craig, E Rochtchina, DA Mackey, P Mitchell

Journal article  |  2005  |  American Journal of Ophthalmology

HMG CoA reductase inhibitors (Statins): Do they have a role in age-related macular degeneration?

RH Guymer, AWI Chin, L Lim, PN Baird

Journal article  |  2005  |  Survey of Ophthalmology

Analysis of the EFEMP1 gene in individuals and families with early onset drusen

N Narendran, RH Guymer, M Cain, PN Baird

Journal article  |  2005  |  Eye

Analysis of optineurin (OPTN) gene mutations in subjects with and without glaucoma: the Blue Mountains Eye Study

PN Baird, AJ Richardson, JE Craig, DA Mackey, E Rochtchina, P Mitchell

Journal article  |  2004  |  Clinical and Experimental Ophthalmology

Association of the M55L and Q192R paraoxonase gene polymorphisms with age-related macular degeneration

PN Baird, D Chu, E Guida, HTV Vu, R Guymer

Journal article  |  2004  |  American Journal of Ophthalmology

Identification of a mutation in the PKD2 gene in a family with age-related macular degeneration

N Narendran, RH Guymer, M Cain, PN Baird

Journal article  |  2004  |  American Journal of Medical Genetics

The epsilon 2 and epsilon 4 alleles of the apolipoprotein gene are associated with age-related macular degeneration

PN Baird, E Guida, DT Chu, HTV Vu, RH Guymer

Journal article  |  2004  |  Investigative Ophthalmology and Visual Science

The 2 and 4 Alleles of the Apolipoprotein Gene Are Associated with Age-Related Macular Degeneration

PN Baird

Journal article  |  2004  |  Investigative Ophthalmology and Visual Science

Analysis of 15 primary open-angle glaucoma families from Australia identifies a founder effect for the Q368STOP mutation of myocilin

PN Baird, JE Craig, AJ Richardson, MA Ring, P Sim, S Stanwix, SJ Foote, DA Mackey

Journal article  |  2003  |  Human Genetics

Analysis of the Arg345Trp disease-associated allele of the EFEMP1 gene in individuals with early onset drusen or familial age-related macular degeneration

RH Guymer, R McNeil, M Cain, B Tomlin, PJ Allen, CL Dip, PN Baird

Journal article  |  2002  |  Clinical and Experimental Ophthalmology

Generating mouse models of retinal disease using ENU mutagenesis

PN Baird, RH Guymer, D Chiu, AL Vincent, WS Alexander, SJ Foote, DJ Hilton

Journal article  |  2002  |  Vision Research

Cholesterol-lowering medications reduce the risk of age-related maculopathy progression

CA McCarty, BN Mukesh, RH Guymer, PN Baird, HR Taylor

Journal article  |  2001  |  Medical Journal of Australia

Evidence for genetic heterogeneity within eight glaucoma families, with the GLC1A Gln368STOP mutation being an important phenotypic modifier

JE Craig, PN Baird, DL Healey, AI McNaught, PJ McCartney, JL Rait, JL Dickinson, L Roe, JH Fingert, EM Stone, DA Mackey

Journal article  |  2001  |  Ophthalmology

Variation of codons 1961 and 2177 of the Stargardt disease gene is not associated with age-related macular degeneration

RH Guymer, E Heon, AJ Lotery, FL Munier, DF Schorderet, PN Baird, RJ McNeil, H Haines, VC Sheffield, EM Stone

Journal article  |  2001  |  Archives of Ophthalmology

The Taa1 restriction enzyme provides a simple means to identify the Q368STOP mutation of the myocilin gene in primary open angle glaucoma

PN Baird, J Dickinson, JE Craig, DA Mackey

Journal article  |  2001  |  American Journal of Ophthalmology

Expression of the Wilms' tumor gene (WT1) in normal hemopoiesis

PN Baird, PJ Simmons

Journal article  |  1997  |  Experimental Hematology

CYTOKINE RECEPTOR GENES - STRUCTURE, CHROMOSOMAL LOCATION, AND INVOLVEMENT IN HUMAN-DISEASE

PN BAIRD, RJ DANDREA, GJ GOODALL

Journal article  |  1995  |  Leukemia & Lymphoma

MOLECULAR-GENETIC ANALYSIS OF CHROMOSOME 11P IN FAMILIAL WILMS-TUMOR

PN BAIRD, J PRITCHARD, JK COWELL

Journal article  |  1994  |  British Journal of Cancer

A NOVEL ZINC-FINGER MUTATION IN A PATIENT WITH DENYS-DRASH SYNDROME

PN BAIRD, JK COWELL

Journal article  |  1993  |  Human Molecular Genetics

INSERTIONAL INACTIVATION OF THE WT1 GENE IN TUMOR-CELLS FROM A PATIENT WITH WAGR SYNDROME

A SANTOS, L OSORIOALMEIDA, PN BAIRD, JM SILVA, MG BOAVIDA, J COWELL

Journal article  |  1993  |  Human Genetics

LOSS OF HETEROZYGOSITY AT 11P13 IN WILMS-TUMORS DOES NOT NECESSARILY INVOLVE MUTATIONS IN THE WT1 GENE

JK COWELL, N GROVES, P BAIRD

Journal article  |  1993  |  British Journal of Cancer

A SINGLE BASE PAIR POLYMORPHISM IN THE WT1 GENE DETECTED BY SINGLE-STRAND CONFORMATION POLYMORPHISM ANALYSIS

N GROVES, PN BAIRD, A HOGG, JK COWELL

Journal article  |  1992  |  Human Genetics

IDENTIFICATION OF MUTATIONS IN THE WT1 GENE IN TUMORS FROM PATIENTS WITH THE WAGR SYNDROME

PN BAIRD, N GROVES, DA HABER, DE HOUSMAN, JK COWELL

Journal article  |  1992  |  Oncogene

Constitutional mutations in the WT1 gene in patients with Denys-Drash syndrome.

PN Baird, A Santos, N Groves, L Jadresic, JK Cowell

Journal article  |  1992  |  Human Molecular Genetics

The Denys-Drash syndrome is characterised by a typical nephropathy, genital abnormalities and also predisposes to the development ..

ONCOGENIC POINT MUTATIONS IN EXON-20 OF THE RB1 GENE IN FAMILIES SHOWING INCOMPLETE PENETRANCE AND MILD EXPRESSION OF THE RETINOBLASTOMA PHENOTYPE

Z ONADIM, A HOGG, PN BAIRD, JK COWELL

Journal article  |  1992  |  Proceedings of the National Academy of Sciences

DETECTION OF HETEROZYGOUS MUTATIONS IN THE RB1 GENE IN RETINOBLASTOMA PATIENTS USING SINGLE-STRAND CONFORMATION POLYMORPHISM ANALYSIS AND POLYMERASE CHAIN-REACTION SEQUENCING

A HOGG, Z ONADIM, PN BAIRD, JK COWELL

Journal article  |  1992  |  Oncogene

LOSS OF HETEROZYGOSITY FOR CHROMOSOME REGION 11P15 IN WILMS-TUMORS IS NOT RELATED TO HRAS GENE TRANSFORMING MUTATIONS

P BAIRD, R WADEY, J COWELL

Journal article  |  1991  |  Oncogene

Identification of two unknown reading frames in Synechococcus 6301 as homologues of the 10k and 65k antigen genes of Mycobacterium tuberculosis and related heat shock genes in E. coli and Coxiella burnetii.

MJ Cookson, PN Baird, LM Hall, AR Coates

Journal article  |  1989  |  Nucleic Acids Research

CLONING AND SEQUENCE-ANALYSIS OF THE 10-KDA ANTIGEN GENE OF MYCOBACTERIUM-TUBERCULOSIS

PN BAIRD, LMC HALL, ARM COATES

Journal article  |  1989  |  Microbiology

A major antigen from Mycobacterium tuberculosis which is homologous to the heat shock proteins groES from E. coli and the htpA gene product of Coxiella burneti.

PN Baird, LM Hall, AR Coates

Journal article  |  1988  |  Nucleic Acids Research