Li Wu

Identification of a novel cDC2-committed progenitor within mouse common dendritic cell progenitor population.

Yujie Tian, Xueheng Guo, Tao Wu, Kuangyu Fei, Li Wu

Journal article  |  2022  |  Protein Cell

Exploration on the "3 2 3" training mode of eight-year program of clinical medicine in Tsinghua University

Daliang Wang, Ning Wu, Lan Xie, Jinping Liu, Ying Qiu, Li Wu

Journal article  |  2021  |  Chinese Journal of Medical Education

Development of an Optimized Culture System for Generating Mouse Alveolar Macrophage-like Cells.

Maocai Luo, Wenlong Lai, Zhimin He, Li Wu

Journal article  |  2021  |  J Immunol

Alveolar macrophages (AMs) play critical roles in maintaining lung homeostasis and orchestrating the immune responses. Although th..

LRRK2 plays essential roles in maintaining lung homeostasis and preventing the development of pulmonary fibrosis.

Yujie Tian, Jiaoyan Lv, Ziyan Su, Tao Wu, Xiaoguang Li, Xiaoyu Hu, Jianhong Zhang, Li Wu

Journal article  |  2021  |  Proc Natl Acad Sci U S A

Perturbation of lung homeostasis is frequently associated with progressive and fatal respiratory diseases, such as pulmonary fibro..

Three paralogous clusters of the miR-17~92 family of microRNAs restrain IL-12-mediated immune defense.

Xiang Zhang, Sinead M Smith, Xi Wang, Baohong Zhao, Li Wu, Xiaoyu Hu

Journal article  |  2021  |  Cell Mol Immunol

MicroRNAs (miRNAs) have been widely implicated in immune regulation, but evidence for the coordinated function of paralogous miRNA..

Dendritic cell fate determination revealed by "SISter" assays.

Tao Wu, Li Wu

Journal article  |  2021  |  Immunity

Establishing the connection between cell fate and fate-related genes in a single progenitor cell is a challenge. In this issue of ..

MicroRNAs of the miR-17~9 family maintain adipose tissue macrophage homeostasis by sustaining IL-10 expression.

Xiang Zhang, Jianguo Liu, Li Wu, Xiaoyu Hu

Journal article  |  2020  |  Elife

Macrophages are critically involved in not only immune and inflammatory responses but also maintenance of metabolic fitness of org..

MicroRNA-148a facilitates inflammatory dendritic cell differentiation and autoimmunity by targeting MAFB.

Yao Meng, Jun Li, Zhizhong Ye, Zhihua Yin, Qing Sun, Zhuojun Liao, Guanhua Li, Jun Deng, Lu Liu, Yuqing Yu, Li Wu, Haibo Zhou, Nan Shen

Journal article  |  2020  |  JCI Insight

Monocyte-derived DCs (moDCs) have been implicated in the pathogenesis of autoimmunity, but the molecular pathways determining the ..

The colonic macrophage transcription factor RBP-J orchestrates intestinal immunity against bacterial pathogens.

Lan Kang, Xiang Zhang, Liangliang Ji, Tiantian Kou, Sinead M Smith, Baohong Zhao, Xiaohuan Guo, Inés Pineda-Torra, Li Wu, Xiaoyu Hu

Journal article  |  2020  |  J Exp Med

Macrophages play pleiotropic roles in maintaining the balance between immune tolerance and inflammatory responses in the gut. Here..

Crosstalk Between Gut Microbiota and Innate Immunity and Its Implication in Autoimmune Diseases

Yuhao Jiao, Li Wu, Nicholas D Huntington, Xuan Zhang

Journal article  |  2020  |  FRONTIERS IN IMMUNOLOGY

The emerging concept of microbiota contributing to local mucosal homeostasis has fueled investigation into its specific role in im..