Tom Brodnicki

T-Cell-Specific PTPN2 Deficiency in NOD Mice Accelerates the Development of Type 1 Diabetes and Autoimmune Comorbidities

Florian Wiede, Thomas C Brodnicki, Pei Kee Goh, Yew A Leong, Gareth W Jones, Di Yu, Alan G Baxter, Simon A Jones, Thomas WH Kay, Tony Tiganis

Journal article  |  2019  |  Diabetes

Type I Interferon Signaling Is Required for Dacryoadenitis in the Nonobese Diabetic Mouse Model of Sjogren Syndrome

Yury Chaly, Jennifer Y Barr, David A Sullivan, Helen E Thomas, Thomas C Brodnicki, Scott M Lieberman

Journal article  |  2018  |  International Journal of Molecular Sciences

GSK3 inhibition, but not epigenetic remodeling, mediates efficient derivation of germline embryonic stem cells from nonobese diabetic mice

Jun Liu, Michelle P Ashton, Moira K O'Bryan, Thomas C Brodnicki, Paul J Verma

Journal article  |  2018  |  Stem Cell Research

Autoimmune-diseaseprone NOD mice help to reveal a new genetic locus for reducing pulmonary disease caused by Mycoplasma pulmonis

NK Wawegama, PF Markham, CM Elso, A Kanci, MS Marenda, GF Browning, TC Brodnicki

Journal article  |  2018  |  Infection and Immunity

© 2018 American Society for Microbiology. Mycoplasmas are bacterial pathogens of a range of animals, including humans, and are a c..

Repurposed JAK1/JAK2 Inhibitor Reverses Established Autoimmune Insulitis in NOD Mice

Prerak M Trivedi, Kate L Graham, Nicholas A Scott, Misty R Jenkins, Suktilang Majaw, Robyn M Sutherland, Stacey Fynch, Andrew M Lew, Christopher J Burns, Balasubramanian Krishnamurthy, Thomas C Brodnicki, Stuart I Mannering, Thomas W Kay, Helen E Thomas

Journal article  |  2017  |  Diabetes

Disruption of Serinc1, which facilitates serine-derived lipid synthesis, fails to alter macrophage function, lymphocyte proliferation or autoimmune disease susceptibility

Edward PF Chu, Colleen M Elso, Abigail H Pollock, May A Alsayb, Leanne Mackin, Helen E Thomas, Thomas WH Kay, Pablo A Silveira, Ashley S Mansell, Katharina Gaus, Thomas C Brodnicki

Journal article  |  2017  |  Molecular Immunology

How to Make Mice Tell the Truth

Helen E Thomas, Thomas C Brodnicki, Thomas WH Kay

Journal article  |  2016  |  Diabetes

Sleeping Beauty Transposon Mutagenesis as a Tool for Gene Discovery in the NOD Mouse Model of Type 1 Diabetes

Colleen M Elso, Edward PF Chu, May A Alsayb, Leanne Mackin, Sean T Ivory, Michelle P Ashton, Stefan Broeer, Pablo A Silveira, Thomas C Brodnicki

Journal article  |  2015  |  G3: Genes|Genomes|Genetics

BIM Deficiency Protects NOD Mice From Diabetes by Diverting Thymocytes to Regulatory T Cells

Balasubramanian Krishnamurthy, Jonathan Chee, Gaurang Jhala, Prerak Trivedi, Tara Catterall, Claudia Selck, Esteban N Gurzov, Thomas C Brodnicki, Kate L Graham, Jibran A Wali, Yifan Zhan, Daniel Gray, Andreas Strasser, Janette Allison, Helen E Thomas, Thomas WH Kay

Journal article  |  2015  |  Diabetes

Increased Autoimmune Diabetes in pIgR-Deficient NOD Mice Is Due to a "Hitchhiking" Interval that Refines the Genetic Effect of Idd5.4

Kim R Simpfendorfer, Richard A Strugnell, Thomas C Brodnicki, Odilia LC Wijburg

Journal article  |  2015  |  PLOS ONE