Emily Karahalios

Adiposity and Endometrial Cancer Risk in Postmenopausal Women: A Sequential Causal Mediation Analysis.

S Ghazaleh Dashti, Dallas R English, Julie A Simpson, Amalia Karahalios, Margarita Moreno-Betancur, Carine Biessy, Sabina Rinaldi, Pietro Ferrari, Anne Tjønneland, Jytte Halkjær, Christina C Dahm, Helene Tilma Vistisen, Florence Menegaux, Vittorio Perduca, Gianluca Severi, Krasimira Aleksandrova, Matthias B Schulze, Giovanna Masala, Sabina Sieri, Rosario Tumino, et al.

Journal article  |  2020  |  Cancer Epidemiology Biomarkers & Prevention

BACKGROUND: Adiposity increases endometrial cancer risk, possibly through inflammation, hyperinsulinemia, and increasing estrogens..

Placebo run-in periods in anticholinergic trials are not associated with treatment effect size or risk of attrition: an empirical evaluation.

Amalia Karahalios, G Peter Herbison, Joanne E McKenzie

Journal article  |  2020  |  Journal of Clinical Epidemiology

OBJECTIVES: We aimed to explore the impact of run-in periods on the magnitude of treatment effect and the risk of attrition in a s..

Leisure-Time Physical Activity Versus Sedentary Behaviour in Relation to Colorectal Adenoma and Cancer: Are these Two Distinct Risk Factors?

Shahid Mahmood, Robert J MacInnis, Amalia Karahalios, Dallas R English, Brigid M Lynch

Journal article  |  2020  |  Current Colorectal Cancer Reports

Design characteristics and statistical methods used in interrupted time series studies evaluating public health interventions: a review.

Simon L Turner, Amalia Karahalios, Andrew B Forbes, Monica Taljaard, Jeremy M Grimshaw, Allen C Cheng, Lisa Bero, Joanne E McKenzie

Journal article  |  2020  |  Journal of Clinical Epidemiology

OBJECTIVES: Interrupted time series (ITS) designs are frequently used in public health to examine whether an intervention or expos..

Response to physical rehabilitation and recovery trajectories following critical illness: individual participant data meta-analysis protocol.

Jennifer RA Jones, Sue Berney, Michael J Berry, D Clark Files, David M Griffith, Luke A McDonald, Peter E Morris, Marc Moss, Amy Nordon-Craft, Timothy Walsh, Ian Gordon, Amalia Karahalios, Zudin Puthucheary, Linda Denehy, undefined CRITICALConnect Study Investigators

Journal article  |  2020  |  BMJ Open

INTRODUCTION: The number of inconclusive physical rehabilitation randomised controlled trials for patients with critical illness i..

Explaining the link between adiposity and colorectal cancer risk in men and postmenopausal women in the UK Biobank: A sequential causal mediation analysis

S Ghazaleh Dashti, Vivian Viallon, Julie A Simpson, Amalia Karahalios, Margarita Moreno-Betancur, Dallas R English, Marc J Gunter, Neil Murphy

Journal article  |  2020  |  International Journal of Cancer

Mechanisms underlying adiposity-colorectal cancer (CRC) association are incompletely understood. Using UK Biobank data, we investi..

Interventions for reducing the use of opioids in breast reconstruction

C Siotos, MA Cheah, A Karahalios, SM Seal, MA Manahan, GD Rosson

Journal article  |  2020  |  Cochrane Database of Systematic Reviews

The cumulative effect of living with disability on mental health in working-age adults: an analysis using marginal structural models

Amalia Karahalios, Frank Pega, Zoe Aitken, Allison Milner, Julie A Simpson, Anne M Kavanagh

Journal article  |  2020  |  Social Psychiatry and Psychiatric Epidemiology: the international journal for research in social and genetic epidemiology and mental health services

PURPOSE: Previous studies have shown that acquiring a disability is associated with a reduction in mental health, but they have no..

A comparison of methods to estimate the survivor average causal effect in the presence of missing data: a simulation study (vol 19, 223, 2019)

Myra B McGuinness, Jessica Kasza, Amalia Karahalios, Robyn H Guymer, Robert P Finger, Julie A Simpson

Journal article  |  2020  |  BMC Medical Research Methodology

In the original publication of this article [1], the incorrect causal diagram was submitted as Fig. 1.

A quantitative bias analysis to estimate measurement error-related attenuation of the association between self-reported physical activity and colorectal cancer risk

Shahid Mahmood, Nga H Nguyen, Julie K Bassett, Robert J MacInnis, Amalia Karahalios, Neville Owen, Fiona J Bruinsma, Roger L Milne, Graham G Giles, Dallas R English, Brigid M Lynch

Journal article  |  2020  |  International Journal of Epidemiology

BACKGROUND: Self-reported physical activity is inaccurate, yet few investigators attempt to adjust for measurement error when esti..