Emily Karahalios

Mobility Deterioration During Acute Pneumonia Illness Is Associated With Increased Hospital Length of Stay and Health Service Costs: An Observational Study

Melanie Lloyd, Emily Callander, Koen Simons, Amalia Karahalios, Graeme Maguire, Edward Janus, Harin Karunajeewa

Journal article  |  2021  |  Cardiopulmonary Physical Therapy Journal

Evaluation of statistical methods used in the analysis of interrupted time series studies: a simulation study.

Simon L Turner, Andrew B Forbes, Amalia Karahalios, Monica Taljaard, Joanne E McKenzie

Journal article  |  2021  |  BMC Med Res Methodol

BACKGROUND: Interrupted time series (ITS) studies are frequently used to evaluate the effects of population-level interventions or..

Comparison of six statistical methods for interrupted time series studies: empirical evaluation of 190 published series.

Simon L Turner, Amalia Karahalios, Andrew B Forbes, Monica Taljaard, Jeremy M Grimshaw, Joanne E McKenzie

Journal article  |  2021  |  BMC Med Res Methodol

BACKGROUND: The Interrupted Time Series (ITS) is a quasi-experimental design commonly used in public health to evaluate the impact..

Latent Class Trajectory Modeling of Adult Body Mass Index and Risk of Obesity-Related Cancer: Findings from the Melbourne Collaborative Cohort Study

Yi Yang, Brigid M Lynch, Pierre-Antoine Dugue, Amalia Karahalios, Robert J MacInnis, Julie K Bassett, Alison McAleese, Craig Sinclair, Graham G Giles, Roger L Milne, Allison M Hodge, Dallas R English

Journal article  |  2021  |  CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

BACKGROUND: Obesity increases the risk of 13 cancer types. Given the long process of carcinogenesis, it is important to determine ..

Adiposity and Endometrial Cancer Risk in Postmenopausal Women: A Sequential Causal Mediation Analysis

S Ghazaleh Dashti, Dallas R English, Julie A Simpson, Amalia Karahalios, Margarita Moreno-Betancur, Carine Biessy, Sabina Rinaldi, Pietro Ferrari, Anne Tjonneland, Jytte Halkjaer, Christina C Dahm, Helene Tilma Vistisen, Florence Menegaux, Vittorio Perduca, Gianluca Severi, Krasimira Aleksandrova, Matthias B Schulze, Giovanna Masala, Sabina Sieri, Rosario Tumino, et al.

Journal article  |  2021  |  CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

BACKGROUND: Adiposity increases endometrial cancer risk, possibly through inflammation, hyperinsulinemia, and increasing estrogens..

Creating effective interrupted time series graphs: Review and recommendations.

Simon L Turner, Amalia Karahalios, Andrew B Forbes, Monica Taljaard, Jeremy M Grimshaw, Elizabeth Korevaar, Allen C Cheng, Lisa Bero, Joanne E McKenzie

Conference Proceedings  |  2021  |  Res Synth Methods

INTRODUCTION: Interrupted Time Series (ITS) studies may be used to assess the impact of an interruption, such as an intervention o..

Placebo run-in periods in anticholinergic trials are not associated with treatment effect size or risk of attrition: an empirical evaluation.

Amalia Karahalios, G Peter Herbison, Joanne E McKenzie

Journal article  |  2020  |  J Clin Epidemiol

OBJECTIVES: We aimed to explore the impact of run-in periods on the magnitude of treatment effect and the risk of attrition in a s..

Leisure-Time Physical Activity Versus Sedentary Behaviour in Relation to Colorectal Adenoma and Cancer: Are these Two Distinct Risk Factors?

Shahid Mahmood, Robert J MacInnis, Amalia Karahalios, Dallas R English, Brigid M Lynch

Journal article  |  2020  |  CURRENT COLORECTAL CANCER REPORTS

Purpose of Review: This literature review provides an up-to-date overview of the evidence relating to the associations of leisure-..

Design characteristics and statistical methods used in interrupted time series studies evaluating public health interventions: a review.

Simon L Turner, Amalia Karahalios, Andrew B Forbes, Monica Taljaard, Jeremy M Grimshaw, Allen C Cheng, Lisa Bero, Joanne E McKenzie

Journal article  |  2020  |  J Clin Epidemiol

OBJECTIVES: Interrupted time series (ITS) designs are frequently used in public health to examine whether an intervention or expos..

Response to physical rehabilitation and recovery trajectories following critical illness: individual participant data meta-analysis protocol.

Jennifer RA Jones, Sue Berney, Michael J Berry, D Clark Files, David M Griffith, Luke A McDonald, Peter E Morris, Marc Moss, Amy Nordon-Craft, Timothy Walsh, Ian Gordon, Amalia Karahalios, Zudin Puthucheary, Linda Denehy, undefined CRITICALConnect Study Investigators

Journal article  |  2020  |  BMJ Open

INTRODUCTION: The number of inconclusive physical rehabilitation randomised controlled trials for patients with critical illness i..