Dr Enzo Porrello heads the Cardiac Regeneration Laboratory at the Murdoch Childrens Research Institute, The Royal Children's Hospital, Melbourne, and is a Senior Research Fellow in the School of Biomedical Sciences at The University of Melbourne.
After completing his PhD in Physiology at The University of Melbourne, Dr Porrello was awarded an NHMRC/NHF C.J. Martin Fellowship to undertake postdoctoral training in Prof Eric Olson's laboratory at UT Southwestern Medical Center in Dallas, USA.
Upon returning to Australia in 2012, Dr Porrello established the Cardiac Regeneration Laboratory at The University of Queensland, which he co-headed together with Dr James Hudson from 2013-2017. Dr Porrello maintains strong links to The University of Queensland where he holds an honorary appointment as an Associate Professor in the School of Biomedical Sciences.
Dr Porrello has made a number of contributions to field of cardiac developmental and regenerative biology over the past 10 years. His discovery of a previously unappreciated developmental window for cardiac regeneration in the neonatal period has opened up an entirely new field of research, which has broad implications for the development of cardiac regenerative therapies for congenital and acquired forms of heart disease. His laboratory has contributed to an enhanced understanding of the transcriptional and epigenetic mechanisms governing cardiomyocyte maturation in the neonatal period, which remains a major area of research focus in his group. Ongoing work harnesses a range of technologies including animal models and human cardiac organoids derived from patient stem cells for disease modeling and drug development.
Dr Porrello curerntly holds an NHMRC Career Development Fellowhsip and a Heart Foundation Future Leader Fellowship. His research has been recognised by a number of prestigious awards including the Metcalf Prize for Stem Cell Research, NHF Paul Korner Innovation Award, Heart Foundation Researcher of the Year (Qld), UQ Foundation for Research Excellence Award, A.K. McIntyre Prize (Australian Physiological Society) and the UT Southwestern Psotdoctoral Achievement Award.
Find out more about Enzo Porrello's experience
Enzo Porrello's highlights
FEATURED Journal article
Epicardial Adipose Tissue Accumulation Confers Atrial Conduction Abnormality.
Read moreEnzo Porrello's selected work
Molecular control of postnatal heart development.
Research Grant
HMGB1 amplifies ILC2-induced type-2 inflammation and airway smooth muscle remodelling
Journal article
AN RNA-BASED STRATEGY FOR HEART REGENERATION
Research Grant
Neonatal heart regeneration: Moving from phenomenology to regenerative medicine
Journal article
Reactivation of Myc transcription in the mouse heart unlocks its proliferative capacity
Conference Proceedings
REACTIVATION OF MYC TRANSCRIPTION IN THE HEART UNLOCKS ITS PROLIFERATIVE CAPACITY
Conference Proceedings
Enzo Porrello's selected work
Projects
Displaying the 2 most recent projects by Enzo Porrello.
Project Types
2
Research Grant
Additional Information
NHMRC CDF and Heart Foundation Future Leader Fellowship, 'An RNA-based strategy for heart regeneration'. 2016-2019
NHMRC Project Grant, 'Understanding the regenerative potential of the human heart in development and disease'. 2019-2022
NHMRC Project Grant, 'Reprogramming adult cardiomyocytes to a neonatal proliferative state for heart regeneration'. 2019-2022
MRFF Accelerated Translation/Stem Cells Australia, 'Bioengineering solutions for congenital heart repair'. 2019-2020
Royal Children's Hospital Foundation, 'Melbourne Children's Centre for Cardiovascular Genomics and Regenerative Medicine (CardioRegen)'. 2018-2021
Scholarly Works
Displaying the 10 most recent scholarly works by Enzo Porrello.
Keyword Analysis
Honours, Awards and Fellowships
School of Biomedical Sciences Teaching Excellence Award
Heart Foundation Queensland Researcher of the Year
Barbara Ell Lecture
Paul Korner Innovation Award
UQ Foundation for Research Excellence Award
A.K. McIntyre Medal
Postdoctoral Research Achievement Award
Dean's Award for Excellence in a PhD Thesis
Dean's Award (Honours Level)
NHMRCF - NHMRC Fellowship
University of Queensland Postdoctoral Research Fellowship
CJMARTIN - C.J. Martin Research Fellowship (National Health & Medical Research Council, Australia)
Credentials
Positions
Positions
Associate Professor
Physiology
Isscr Member
International Society for Stem Cell Research (ISSCR)
Australasian Section Council Member Of The International Society For Heart Research (Ishr)
International Society for Heart Research (Australasian Section)
Aha Member
American Heart Association (AHA)
Aups Member
Australian Physiological Society (AuPS)
Ishr Member
International Society for Heart Research (ISHR)
Education
Education
Doctor of Philosophy
University of Melbourne
Bachelor of Science
University of Melbourne
Bachelor of Biomedical Science
University of Melbourne