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Chronic isolation stress is associated with increased colonic and motor symptoms in the A5..
Displaying the 18 most recent projects by Vicki Lawson.
Internal Research Grant
Displaying the 65 most recent scholarly works by Vicki Lawson.
Misfolded α-synuclein causes hyperactive respiration without functional deficit in live neuroblastoma cells.
CL Ugalde, SJ Annesley, S Gordon, K Mroczek, MA Perugini, VA Lawson, PR Fisher, DI Finkelstein, AF Hill
Journal article | 2019 | Disease Models & Mechanisms
The misfolding and aggregation of the largely disordered protein, α-synuclein, is a central pathogenic event that occurs in the sy..
Chronic isolation stress is associated with increased colonic and motor symptoms in the A53T mouse model of Parkinson's disease
Shanti Diwakarla, David I Finkelstein, Remy Constable, Olivia Artaiz, Madeleine Di Natale, Rachel M McQuade, Enie Lei, Xin-yi Chai, Mitchell T Ringuet, Linda J Fothergill, Victoria A Lawson, Laura J Ellett, Joel P Berger, John B Furness
Journal article | 2019 | Neurogastroenterology & Motility
BACKGROUND: Chronic stress exacerbates motor deficits and increases dopaminergic cell loss in several rodent models of Parkinson's..
Early existence and biochemical evolution characterise acutely synaptotoxic PrPSc
Simote Totauhelotu Foliaki, Victoria Lewis, Abu Mohammed Taufiqual Islam, Laura Jane Ellett, Matteo Senesi, David Isaac Finkelstein, Blaine Roberts, Victoria A Lawson, Paul Anthony Adlard, Steven John Collins
Journal article | 2019 | PLOS Pathogens
Prion acute synaptotoxicity is largely driven by protease-resistant PrPSc species
Simote Totauhelotu Foliaki, Victoria Lewis, David Isaac Finkelstein, Victoria Lawson, Harold Arthur Coleman, Matteo Senesi, Abu Mohammed Taufiqual Islam, Feng Chen, Shannon Sarros, Blaine Roberts, Paul Anthony Adlard, Steven John Collins
Journal article | 2018 | PLOS Pathogens
Pathogenic Mutations within the Hydrophobic Domain of the Prion Protein Lead to the Formation of Protease-Sensitive Prion Species with Increased Lethality
Bradley M Coleman, Christopher F Harrison, Belinda Guo, Colin L Masters, Kevin J Barnham, Victoria A Lawson, Andrew F Hill
Journal article | 2014 | Journal of Virology
Prion Infection Impairs Cholesterol Metabolism in Neuronal Cells
Huanhuan L Cui, Belinda Guo, Benjamin Scicluna, Bradley M Coleman, Victoria A Lawson, Laura Ellett, Peter J Meikle, Michael Bukrinsky, Nigora Mukhamedova, Dmitri Sviridov, Andrew F Hill
Journal article | 2014 | Journal of Biological Chemistry
Acute exposure to prion infection induces transient oxidative stress progressing to be cumulatively deleterious with chronic propagation in vitro
Cathryn L Haigh, Amelia R McGlade, Victoria Lewis, Colin L Masters, Victoria A Lawson, Steven J Collins
Journal article | 2011 | Free Radical Biology and Medicine
Near-Infrared Fluorescence Imaging of Apoptotic Neuronal Cell Death in a Live Animal Model of Prion Disease
Victoria A Lawson, Cathryn L Haigh, Blaine Roberts, Vijaya B Kenche, Helen MJ Klemm, Colin L Masters, Steven J Collins, Kevin J Barnham, Simon C Drew
Journal article | 2010 | ACS Chemical Neuroscience
Glycosaminoglycan Sulphation Affects the Seeded Misfolding of a Mutant Prion Protein
Victoria A Lawson, Brooke Lumicisi, Jeremy Welton, Dorothy Machalek, Katrina Gouramanis, Helen M Klemm, James D Stewart, Colin L Masters, David E Hoke, Steven J Collins, Andrew F Hill
Journal article | 2010 | PLoS One
Residues Surrounding the Glycosylphosphatidylinositol Anchor Attachment Site of PrP Modulate Prion Infection: Insight from the Resistance of Rabbits to Prion Disease
Rebecca M Nisbet, Christopher F Harrison, Victoria A Lawson, Colin L Masters, Roberto Cappai, Andrew F Hill
Journal article | 2010 | Journal of Virology
Evidence for prion protein expression in enteroglial cells of the myenteric plexus of mouse intestine
Valeria Albanese, Victoria A Lawson, Andrew F Hill, Cappai Roberto, Giovanni Di Guardo, Vasiliki Stalkopoulos, Michelle Thacker, John B Furness, Roberto Chiocchetti
Journal article | 2008 | Autonomic Neuroscience - Basic & Clinical
Mouse-adapted sporadic human Creutzfeldt-Jakob disease prions propagate in cell culture
Victoria A Lawson, Laura J Velia, James D Stewart, Robyn A Sharples, Helen Klemm, Dorothy M Machalek, Colin L Masters, Roberto Cappai, Steven J Collins, Andrew F Hill
Journal article | 2008 | International Journal of Biochemistry and Cell Biology
Viral phenotypes and antibody responses in long-term survivors infected with attenuated human immunodeficiency virus type 1 containing deletions in the nef and long terminal repeat regions
Erin E Verity, Dimitra Zotos, Kim Wilson, Catherine Chatfield, Victoria A Lawson, Dominic E Dwyer, Anthony Cunningham, Jennifer Learmont, Wayne Dyer, John Sullivan, Melissa Churchill, Steven L Wesselingh, Dana Gabuzda, Paul R Gorry, Dale A McPhee
Journal article | 2007 | Journal of Virology
Correlative studies support lipid peroxidation is linked to PrPres propagation as art early primary pathogenic event in prion disease
MW Brazier, V Lewis, GD Ciccotosto, GM Klub, VA Lawson, R Cappai, JW Ironside, CL Masters, AF Hill, AR White, S Collins
Journal article | 2006 | Brain Research Bulletin
Apoptosis induced in synchronized human immunodeficiency virus type 1-infected primary peripheral blood mononuclear cells is detected after the peak of CD4 T-lymphocyte loss and is dependent on the tropism of the gp120 envelope glycoprotein
VA Lawson, KA Silburn, PR Gorry, G Paukovic, DFJ Purcell, AL Greenway, DA McPhee
Journal article | 2004 | Journal of Virology
Rapid full-length genomic sequencing of two cytopathically heterogeneous Australian primary HIV-1 isolates.
RB Oelrichs, VA Lawson, KM Coates, C Chatfield, NJ Deacon, DA McPhee
Journal article | 2000 | Journal of Biomedical Science
Two Australian HIV-1 isolates, derived from patient blood (HIV(MBC200)) and cerebrospinal fluid (HIV(MBC925)), were characterized ..
GENOMIC STRUCTURE OF AN ATTENUATED QUASI-SPECIES OF HIV-1 FROM A BLOOD-TRANSFUSION DONOR AND RECIPIENTS
NJ DEACON, A TSYKIN, A SOLOMON, K SMITH, M LUDFORDMENTING, DJ HOOKER, DA MCPHEE, AL GREENWAY, A ELLETT, C CHATFIELD, VA LAWSON, S CROWE, A MAERZ, S SONZA, J LEARMONT, JS SULLIVAN, A CUNNINGHAM, D DWYER, D DOWTON, J MILLS
Journal article | 1995 | Science
Honours, Awards and Fellowships
NHMRC Howard Florey Centenary Fellowship
Biomedical research scholarship