Benjamin Goudey

Letter: improved parsimony of genetic risk scores for coeliac disease through refined HLA modelling

Michael Erlichster, Justin Bedo, Efstratios Skafidas, Patrick Kwan, Adam Kowalczyk, Benjamin Goudey

Journal article  |  2021  |  Alimentary Pharmacology & Therapeutics

Improved HLA-based prediction of coeliac disease identifies two novel genetic interactions

Michael Erlichster, Justin Bedo, Efstratios Skafidas, Patrick Kwan, Adam Kowalczyk, Benjamin Goudey

Journal article  |  2020  |  European Journal of Human Genetics

Human Leucocyte Antigen (HLA) testing is useful in the clinical work-up of coeliac disease (CD) with high negative but low positiv..

Exploring effective approaches for haplotype block phasing.

Ziad Al Bkhetan, Justin Zobel, Adam Kowalczyk, Karin Verspoor, Benjamin Goudey

Journal article  |  2019  |  BMC Bioinformatics

BACKGROUND: Knowledge of phase, the specific allele sequence on each copy of homologous chromosomes, is increasingly recognized as..

Cross-ethnicity tagging SNPs for HLA alleles associated with adverse drug reaction

Michael Erlichster, Benjamin Goudey, Efstratios Skafidas, Patrick Kwan

Journal article  |  2019  |  The Pharmacogenomics Journal

Reduction of adverse drug reaction (ADR) incidence through screening of predisposing human leucocyte antigen (HLA) alleles is a pr..

A blood-based signature of cerebrospinal fluid A beta(1-42) status

Benjamin Goudey, Bowen J Fung, Christine Schieber, Noel G Faux, Michael W Weiner, Paul Aisen, Ronald Petersen, Clifford R Jack, William Jagust, John Q Trojanowki, Arthur W Toga, Laurel Beckett, Robert C Green, Andrew J Saykin, John Morris, Leslie M Shaw, Jeffrey Kaye, Joseph Quinn, Lisa Silbert, Betty Lind, et al.

Journal article  |  2019  |  SCIENTIFIC REPORTS

It is increasingly recognized that Alzheimer's disease (AD) exists before dementia is present and that shifts in amyloid beta occu..

Improved HLA-based prediction of coeliac disease identifies two novel HLA risk modifiers, DQ6.2 and DQ7.3

Michael Erlichster, Justin Bedo, Efstratios Skafidas, Patrick Kwan, Adam Kowalczyk, Benjamin Goudey

Journal article  |  2019

Abstract Purpose Human Leukocyte Antigen (HLA) testing is useful in the clinical work-up of coeliac disease (CD), with high negati..

A framework for optimal health worker allocation in under-resourced regions

B Goudey, RI Hickson, CKH Hettiarachchige, M Pore, C Reeves, OJ Smith, A Swan

Journal article  |  2017  |  IBM JOURNAL OF RESEARCH AND DEVELOPMENT

The effectiveness of health systems is dependent on the availability of health workers and their distribution across a healthcare ..

A blood-based signature of cerebral spinal fluid Aβ1–42 status

Benjamin Goudey, Bowen Fung, Christine Schieber, Noel Faux, undefined for the Alzheimer’s Disease Metabolomics Consortium, undefined for the Alzheimer’s Disease Neuroimaging Initiative

Journal article  |  2017

ABSTRACT It is increasingly recognized that Alzheimer’s disease (AD) exists before dementia is present and that shifts in amyloid ..

Interactions within the MHC contribute to the genetic architecture of celiac disease

Benjamin Goudey, Gad Abraham, Eder Kikianty, Qiao Wang, Dave Rawlinson, Fan Shi, Izhak Haviv, Linda Stern, Adam Kowalczyk, Michael Inouye

Journal article  |  2017  |  PLOS ONE

Interaction analysis of GWAS can detect signal that would be ignored by single variant analysis, yet few robust interactions in hu..

Use of a Novel Nonparametric Version of DEPTH to Identify Genomic Regions Associated with Prostate Cancer Risk

Robert J MacInnis, Daniel F Schmidt, Enes Makalic, Gianluca Severi, Liesel M FitzGerald, Matthias Reumann, Miroslaw K Kapuscinski, Adam Kowalczyk, Zeyu Zhou, Benjamin Goudey, Guoqi Qian, Quang M Bui, Daniel J Park, Adam Freeman, Melissa C Southey, Ali Amin Al Olama, Zsofia Kote-Jarai, Rosalind A Eeles, John L Hopper, Graham G Giles

Journal article  |  2016  |  CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

BACKGROUND: We have developed a genome-wide association study analysis method called DEPTH (DEPendency of association on the numbe..