Bradford Moffat

OnabotulinumtoxinA treatment for MS-tremor modifies fMRI tremor response in central sensory-motor integration areas

Frederique MC Boonstra, Andrew Evans, Gustavo Noffs, Thushara Perera, Vilija Jokubaitis, Jim Stankovich, Adam P Vogel, Bradford A Moffat, Helmut Butzkueven, Scott C Kolbe, Anneke van der Walt

Journal article  |  2020  |  Multiple Sclerosis and Related Disorders

BACKGROUND: Treatment of tremor in MS is an unmet need. OnabotulinumtoxinA (BoNT-A) has shown promising results; however, little i..

Extracting more for less: multi-echo MP2RAGE for simultaneous T-1-weighted imaging, T-1 mapping, R2*mapping, SWI, and QSM from a single acquisition

Hongfu Sun, Jon O Cleary, Rebecca Glarin, Scott C Kolbe, Roger J Ordidge, Bradford A Moffat, G Bruce Pike

Journal article  |  2019  |  Magnetic Resonance in Medicine

Compressed sensing effects on quantitative analysis of undersampled human brain sodium MRI

Yasmin Blunck, Scott C Kolbe, Bradford A Moffat, Roger J Ordidge, Jon O Cleary, Leigh A Johnston

Journal article  |  2019  |  Magnetic Resonance in Medicine

Normative retrobulbar measurements of the optic nerve using ultra high field magnetic resonance imaging

Bao N Nguyen, Jon O Cleary, Rebecca Glarin, Scott C Kolbe, Bradford A Moffat, Roger J Ordidge, Bang V Bui, Allison M McKendrick

Conference Proceedings  |  2019  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Phantom measurement predicts the impact of image reconstruction on Florbetapir SUVR quantification

Robert Williams, Leigh Johnston, Vincent Dore, Graeme O'Keefe, Jason Callahan, Zhihan Xu, Shuning Zheng, Bradford Moffat, Colin Masters, Christopher Rowe

Conference Proceedings  |  2019  |  JOURNAL OF NUCLEAR MEDICINE

Functional neuroplasticity in response to cerebello-thalamic injury underpins the clinical presentation of tremor in multiple sclerosis.

Frederique Mc Boonstra, Gustavo Noffs, Thushara Perera, Vilija G Jokubaitis, Adam P Vogel, Bradford A Moffat, Helmut Butzkueven, Andrew Evans, Anneke van der Walt, Scott C Kolbe

Journal article  |  2019  |  Multiple Sclerosis Journal

BACKGROUND:: Tremor is present in almost half of multiple sclerosis (MS) patients. The lack of understanding of its pathophysiolog..

Glutamate weighted imaging contrast in gliomas with 7 Tesla magnetic resonance imaging

Andrew Morokoff, Bradford A Moffat, Joel M Stein, Ravi Prakash Reddy Nanga, Patricia Desmond, Russell T Shinohara, Hari Hariharan, Rebecca Glarin, Katharine Drummond, Patrick Kwan, Ravinder Reddy, Terence J O'BRIEN, Kathryn A Davis

Journal article  |  2019  |  NeuroImage: Clinical

INTRODUCTION: Diffuse gliomas are incurable malignancies, which undergo inevitable progression and are associated with seizure in ..

Zero-gradient-excitation ramped hybrid encoding (zG(RF)-RHE) sodium MRI

Yasmin Blunck, Bradford A Moffat, Scott C Kolbe, Roger J Ordidge, Jon O Cleary, Leigh A Johnston

Journal article  |  2019  |  Magnetic Resonance in Medicine

Feasibility of identifying the ideal locations for motor intention decoding using unimodal and multimodal classification at 7T-fMRI

Peter E Yoo, Thomas J Oxley, Sam E John, Nicholas L Opie, Roger J Ordidge, Terence J O'Brien, Maureen A Hagan, Yan T Wong, Bradford A Moffat

Journal article  |  2018  |  Scientific Reports

Comparison between site and central radiological assessments for patients with recurrent glioblastoma on a clinical trial

Kathryn M Field, Greg Fitt, Mark A Rosenthal, John Simes, Anna K Nowak, Elizabeth H Barnes, Kate Sawkins, Christine Goh, Bradford A Moffat, Simon Salinas, Lawrence Cher, Helen Wheeler, Elizabeth J Hovey, Pramit M Phal

Journal article  |  2018  |  Asia-Pacific Journal of Clinical Oncology

Optimized partial-coverage functional analysis pipeline (OPFAP): a semi-automated pipeline for skull stripping and co-registration of partial-coverage, ultra-high-field functional images

Peter E Yoo, Jon O Cleary, Scott C Kolbe, Roger J Ordidge, Terence J O'Brien, Nicholas L Opie, Sam E John, Thomas J Oxley, Bradford A Moffat

Journal article  |  2018  |  Magnetic Resonance Materials in Physics, Biology and Medicine

A tunable one-pot three-component synthesis of an I-125 and Gd-labelled star polymer nanoparticle for hybrid imaging with MRI and nuclear medicine

Lars Esser, Nigel A Lengkeek, Bradford A Moffat, Mai N Vu, Ivan Greguric, John F Quinn, Thomas P Davis, Michael R Whittaker

Journal article  |  2018  |  Polymer Chemistry

Novel Functional MRI Task for Studying the Neural Correlates of Upper Limb Tremor

Frederique MC Boonstra, Thushara Perera, Gustavo Noffs, Cassandra Marotta, Adam P Vogel, Andrew H Evans, Helmut Butzkueven, Bradford A Moffat, Anneke van der Walt, Scott C Kolbe

Journal article  |  2018  |  Frontiers in Neurology

Spatially dynamic recurrent information flow across long-range dorsal motor network encodes selective motor goals

Peter E Yoo, Maureen A Hagan, Sam E John, Nicholas L Opie, Roger J Ordidge, Terence J O'Brien, Thomas J Oxley, Bradford A Moffat, Yan T Wong

Journal article  |  2018  |  Human Brain Mapping

Nano-assemblies of cationic mPEG brush block copolymers with gadolinium polyoxotungstate [Gd(W5O18)(2)](9-) form stable, high relaxivity MRI contrast agents

Joanne Ly, Yuhuan Li, Mai N Vu, Bradford A Moffat, Kevin S Jack, John F Quinn, Michael R Whittaker, Thomas P Davis

Journal article  |  2018  |  Nanoscale

3D-multi-echo radial imaging of Na-23 (3D-MERINA) for time-efficient multi-parameter tissue compartment mapping

Yasmin Blunck, Sonal Josan, Syeda Warda Taqdees, Bradford A Moffat, Roger J Ordidge, Jon O Cleary, Leigh A Johnston

Journal article  |  2018  |  Magnetic Resonance in Medicine

An Objective Measurement of Lacunar Infarct Location from the Middle Cerebral Artery Stem

Shanal S Kumar, Bradford A Moffat, Simon Salinas, Leonid Churilov, Bernard Yan

Journal article  |  2018  |  Journal of Stroke and Cerebrovascular Diseases

Emotional reactivity following surgery to the prefrontal cortex

Lisanne M Jenkins, David G Andrewes, Christian L Nicholas, Katharine J Drummond, Bradford A Moffat, Pramit M Phal, Patricia Desmond

Conference Proceedings  |  2018  |  Journal of the International Neuropsychological Society

Technologies for Advanced Gait and Balance Assessments in People with Multiple Sclerosis

Camille J Shanahan, Frederique MC Boonstra, L Eduardo Cofre Lizama, Myrte Strik, Bradford A Moffat, Fary Khan, Trevor J Kilpatrick, Anneke van der Walt, Mary P Galea, Scott C Kolbe

Journal article  |  2018  |  Frontiers in Neurology

7T-fMRI: Faster temporal resolution yields optimal BOLD sensitivity for functional network imaging specifically at high spatial resolution

Peter E Yoo, Sam E John, Shawna Farquharson, Jon O Cleary, Yan T Wong, Amanda Ng, Claire B Mulcahy, David B Grayden, Roger J Ordidge, Nicholas L Opie, Terence J O'Brien, Thomas J Oxley, Bradford A Moffat

Journal article  |  2018  |  NeuroImage

Tremor in multiple sclerosis is associated with cerebello-thalamic pathology

Frederique Boonstra, Grace Florescu, Andrew Evans, Chris Steward, Peter Mitchell, Patricia Desmond, Brad Moffat, Helmut Butzkueven, Scott Kolbe, Anneke van der Walt

Journal article  |  2017  |  Journal of Neural Transmission

Dual-modality NIRF-MRI cubosomes and hexosomes: High throughput formulation and in vivo biodistribution

Tran Nhiem, Nicole Bye, Bradford A Moffat, David K Wright, Andrew Cuddihy, Tracey M Hinton, Adrian M Hawley, Nicholas P Reynolds, Lynne J Waddington, Xavier Mulet, Ann M Turnley, M Cristina Morganti-Kossmann, Benjamin W Muir

Journal article  |  2017  |  Materials Science and Engineering: C

Early perfusion MRI predicts survival outcome in patients with recurrent glioblastoma treated with bevacizumab and carboplatin

Iwan E Bennett, Kathryn M Field, Christopher M Hovens, Bradford A Moffat, Mark A Rosenthal, Katharine Drummond, Andrew H Kaye, Andrew P Morokoff

Journal article  |  2017  |  Journal of Neuro-Oncology

Assessment of Optic Pathway Structure and Function in Patients With Compression of the Optic Chiasm: A Correlation With Optical Coherence Tomography

Pramit M Phal, Christopher Steward, Andrew D Nichols, Chris Kokkinos, Patricia M Desmond, Helen Danesh-Meyer, Yuval Z Sufaro, Andrew H Kaye, Bradford A Moffat

Journal article  |  2016  |  Investigative Opthalmology & Visual Science

Development and Implementation of a Corriedale Ovine Brain Atlas for Use in Atlas-Based Segmentation

Kishan Andre Liyanage, Christopher Steward, Bradford Armstrong Moffat, Nicholas Lachlan Opie, Gil Simon Rind, Sam Emmanuel John, Stephen Ronayne, Clive Newton May, Terence John O'Brien, Marjorie Eileen Milne, Thomas James Oxley

Journal article  |  2016  |  PLOS ONE

Development of representative magnetic resonance imaging-based atlases of the canine brain and evaluation of three methods for atlas-based segmentation

Marjorie E Milne, Christopher Steward, Simon M Firestone, Sam N Long, Terrence J O'Brien, Bradford A Moffat

Journal article  |  2016  |  American Journal of Veterinary Research

Minimally invasive endovascular stent-electrode array for high-fidelity, chronic recordings of cortical neural activity

Thomas J Oxley, Nicholas L Opie, Sam E John, Gil S Rind, Stephen M Ronayne, Tracey L Wheeler, Jack W Judy, Alan J McDonald, Anthony Dornom, Timothy JH Lovell, Christopher Steward, David J Garrett, Bradford A Moffat, Elaine H Lui, Nawaf Yassi, Bruce CV Campbell, Yan T Wong, Kate E Fox, Ewan S Nurse, Iwan E Bennett, et al.

Journal article  |  2016  |  Nature biotechnology

Association between baseline peri-infarct magnetic resonance spectroscopy and regional white matter atrophy after stroke

Nawaf Yassi, Bruce CV Campbell, Bradford A Moffat, Christopher Steward, Leonid Churilov, Mark W Parsons, Geoffrey A Donnan, Patricia M Desmond, Stephen M Davis, Andrew Bivard

Journal article  |  2016  |  Neuroradiology

Gadolinium-functionalized nanoparticles for application as magnetic resonance imaging contrast agents via polymerization-induced self-assembly

Lars Esser, Nghia P Truong, Bunyamin Karagoz, Bradford A Moffat, Cyrille Boyer, John F Quinn, Michael R Whittaker, Thomas P Davis

Journal article  |  2016  |  Polymer Chemistry

Semi-automated Hippocampal Segmentation in People With Cognitive Impairment Using an Age Appropriate Template for Registration

Bernd Merkel, Christopher Steward, Lucy Vivash, Charles B Malpas, Pramit Phal, Bradford A Moffat, Kay L Cox, Kathryn A Ellis, David J Ames, Elizabeth V Cyarto, Michelle MY Lai, Matthew J Sharman, Cassandra Szoeke, Colin L Masters, Nicola T Lautenschlager, Patricia Desmond

Journal article  |  2015  |  J Magn Reson Imaging

Preoperative biomarkers of tumour vascularity are elevated in patients with glioblastoma multiforme

Iwan E Bennett, Hui Guo, Nicole Kountouri, Giovanna M D'abaco, Christopher M Hovens, Bradford A Moffat, Patricia Desmond, Katharine Drummond, Andrew H Kaye, Andrew P Morokoff

Journal article  |  2015  |  Journal of Clinical Neuroscience

Alterations in dorsal and ventral posterior cingulate connectivity in APOE epsilon 4 carriers at risk of Alzheimer's disease

Rebecca Kerestes, Pramit M Phal, Chris Steward, Bradford A Moffat, Simon Salinas, Kay L Cox, Kathryn A Ellis, Elizabeth V Cyarto, David Ames, Ralph N Martins, Colin L Masters, Christopher C Rowe, Matthew J Sharman, Olivier Salvado, Cassandra Szoeke, Michelle Lai, Nicola T Lautenschlager, Patricia M Desmond

Journal article  |  2015  |  BJPsych Open

Know your tools-concordance of different methods for measuring brain volume change after ischemic stroke

Nawaf Yassi, Bruce CV Campbell, Bradford A Moffat, Christopher Steward, Leonid Churilov, Mark W Parsons, Patricia M Desmond, Stephen M Davis, Andrew Bivard

Journal article  |  2015  |  Neuroradiology

A novel literature-based approach to identify genetic and molecular predictors of survival in glioblastoma multiforme: Analysis of 14,678 patients using systematic review and meta-analytical tools

Matthew NT Thuy, Jeremy KT Kam, Geoffrey CY Lee, Peter L Tao, Dorothy Q Ling, Melissa Cheng, Su Kah Goh, Alexander J Papachristos, Lipi Shukla, Krystal-Leigh Wall, Nicolas R Smoll, Jordan J Jones, Njeri Gikenye, Bob Soh, Brad Moffat, Nick Johnson, Katharine J Drummond

Journal article  |  2015  |  Journal of Clinical Neuroscience

Probabilistic MRI Tractography of the Optic Radiation Using Constrained Spherical Deconvolution: A Feasibility Study

Jeremy C Lim, Pramit M Phal, Patricia M Desmond, Andrew D Nichols, Chris Kokkinos, Helen V Danesh-Meyer, Andrew H Kaye, Bradford A Moffat

Journal article  |  2015  |  PLOS ONE

Colloidally Stabilized Magnetic Carbon Nanotubes Providing MRI Contrast in Mouse Liver Tumors

Yue Liu, Benjamin W Muir, Lynne J Waddington, Tracey M Hinton, Bradford A Moffat, Xiaojuan Hao, Jieshan Qiu, Timothy C Hughes

Journal article  |  2015  |  Biomacromolecules

Contralesional Thalamic Surface Atrophy and Functional Disconnection 3 Months after Ischemic Stroke

Nawaf Yassi, Charles B Malpas, Bruce CV Campbell, Bradford Moffat, Christopher Steward, Mark W Parsons, Patricia M Desmond, Geoffrey A Donnan, Stephen M Davis, Andrew Bivard

Journal article  |  2015  |  Cerebrovascular Diseases

Social cognition in patients following surgery to the prefrontal cortex

Lisanne Michelle Jenkins, David Gordon Andrewes, Christian Luke Nicholas, Katharine Jann Drummond, Bradford Armstrong Moffat, Pramit Phal, Patricia Desmond, Roy Peter Caspar Kessels

Journal article  |  2014  |  Psychiatry Research: Neuroimaging

IDH1 mutation is associated with seizures and protoplasmic subtype in patients with low-grade gliomas

Simon V Liubinas, Giovanna M D'Abaco, Bradford M Moffat, Michael Gonzales, Frank Feleppa, Cameron J Nowell, Alexandra Gorelik, Katharine J Drummond, Terence J O'Brien, Andrew H Kaye, Andrew P Morokoff

Journal article  |  2014  |  Epilepsia

Nitroxide-Loaded Hexosomes Provide MRI Contrast in Vivo

Nicole Bye, Oliver E Hutt, Tracey M Hinton, Durga P Acharya, Lynne J Waddington, Bradford A Moffat, David K Wright, Hong X Wang, Xavier Mulet, Benjamin W Muir

Journal article  |  2014  |  Langmuir

Tumour associated epilepsy and glutamate excitotoxicity in patients with gliomas

Simon V Liubinas, Terence J O'Brien, Bradford M Moffat, Katharine J Drummond, Andrew P Morokoff, Andrew H Kaye

Journal article  |  2014  |  Journal of Clinical Neuroscience

Glutamate quantification in patients with supratentorial gliomas using chemical shift imaging

SV Liubinas, KJ Drummond, PM Desmond, A Bjorksten, AP Morokoff, AH Kaye, TJ O'Brien, BA Moffat

Journal article  |  2014  |  NMR in Biomedicine

Water-dispersible magnetic carbon nanotubes as T-2-weighted MRI contrast agents

Yue Liu, Timothy C Hughes, Benjamin W Muir, Lynne J Waddington, Thomas R Gengenbach, Christopher D Easton, Tracey M Hinton, Bradford A Moffat, Xiaojuan Hao, Jieshan Qiu

Journal article  |  2014  |  Biomaterials

Mesoporous Europo-Gadolinosilicate Nanoparticles as Bimodal Medical Imaging Agents and a Potential Theranostic Platform

Nicholas MK Tse, Danielle F Kennedy, Nigel Kirby, Bradford A Moffat, Benjamin W Muir, Rachel A Caruso, Calum J Drummond

Journal article  |  2013  |  Advanced Healthcare Materials

Description of technique and lower reference limit for magnetic resonance imaging of hippocampal volumetry in dogs

Marjorie E Milne, Garry A Anderson, Kathleen E Chow, Terrence J O'Brien, Bradford A Moffat, Sam N Long

Journal article  |  2013  |  American Journal of Veterinary Research

Mesoporous gadolino-aluminosilicate nanoparticles as magnetic resonance imaging contrast agents

Nicholas MK Tse, Danielle F Kennedy, Nigel Kirby, Bradford A Moffat, Tracey M Hinton, Benjamin W Muir, Rachel A Caruso, Calum J Drummond

Journal article  |  2013  |  Journal of Materials Chemistry B

Metal-free and MRI visible theranostic lyotropic liquid crystal nitroxide-based nanoparticles

Benjamin W Muir, Durga P Acharya, Danielle F Kennedy, Xavier Mulet, Richard A Evans, Suzanne M Pereira, Kim L Wark, Ben J Boyd, Tr-Hung Nguyen, Tracey M Hinton, Lynne J Waddington, Nigel Kirby, David K Wright, Hong X Wang, Gary E Egan, Bradford A Moffat

Journal article  |  2012  |  Biomaterials

High throughput preparation of hexagonally ordered mesoporous silica and gadolinosilicate nanoparticles for use as MRI contrast agents

N TSE, undefined kennedy, BA Moffat, undefined Kirby, RA Caruso, undefined Drummond

Journal article  |  2012  |  ACS Combinatorial Science

Cubic mesophase nanoparticles doped with superparamagnetic iron oxide nanoparticles: a new class of MRI contrast agent

Durga P Acharya, Bradford A Moffat, Anastasios Polyzos, Lynne Waddington, Greg Coia, David K Wright, Hong X Wang, Gary F Egan, Benjamin W Muir, Patrick G Hartley

Journal article  |  2012  |  RSC Advances: an international journal to further the chemical sciences

Comparative Study of the Magnetic Behavior of Spherical and Cubic Superparamagnetic Iron Oxide Nanoparticles

Guoliang Zhen, Benjamin W Muir, Bradford A Moffat, Peter Harbour, Keith S Murray, Boujemaa Moubaraki, Kiyonori Suzuki, Ian Madsen, Nicki Agron-Olshina, Lynne Waddington, Paul Mulvaney, Patrick G Hartley

Journal article  |  2011  |  Journal of Physical Chemistry C

Evaluation of Treatment-Associated Inflammatory Response on Diffusion-Weighted Magnetic Resonance Imaging and 2-[F-18]-Fluoro-2-Deoxy-D-Glucose-Positron Emission Tomography Imaging Biomarkers

Craig J Galban, Mahaveer S Bhojani, Kuei C Lee, Charles R Meyer, Marcian E Van Dort, Kyle K Kuszpit, Robert A Koeppe, Rajesh Ranga, Bradford A Moffat, Timothy D Johnson, Thomas L Chenevert, Alnawaz Rehemtulla, Brian D Ross

Journal article  |  2010  |  Clinical Cancer Research

Substantiating in vivo magnetic brain tumor targeting of cationic iron oxide nanocarriers via adsorptive surface masking

Beata Chertok, Allan E David, Bradford A Moffat, Victor C Yang

Journal article  |  2009  |  Biomaterials

Advanced MRI: Translation from Animal to Human in Brain Tumor Research

Bradford A Moffat, Craig J Galban, Alnawaz Rehemtulla

Journal article  |  2009  |  Neuroimaging Clinics of North America

Combinatorial Discovery of Novel Amphiphilic Polymers for the Phase Transfer of Magnetic Nanoparticles

Benjamin W Muir, Bradford A Moffat, Peter Harbour, Greg Coia, Guoliang Zhen, Lynne Waddington, Judith Scoble, Daniel Krah, San H Thang, Yen K Chong, Paul Mulvaney, Patrick Hartley

Journal article  |  2009  |  Physical Chemistry Chemical Physics

A Feasibility Study of Parametric Response Map Analysis of Diffusion-Weighted Magnetic Resonance Imaging Scans of Head and Neck Cancer Patients for Providing Early Detection of Therapeutic Efficacy

Craig J Galban, Suresh K Mukherji, Thomas L Chenevert, Charles R Meyer, Daniel A Hamstra, Peyton H Bland, Timothy D Johnson, Bradford A Moffat, Alnawaz Rehemtulla, Avraham Eisbruch, Brian D Ross

Journal article  |  2009  |  Translational Oncology

Diffusion Magnetic Resonance Imaging: An Imaging Treatment Response Biomarker to Chemoradiotherapy in a Mouse Model of Squamous Cell Cancer of the Head and Neck

Daniel A Hamstra, Kuei C Lee, Bradford A Moffat, Thomas L Chenevert, Alnawaz Rehemtulla, Brian D Ross

Journal article  |  2008  |  Translational Oncology

Iron oxide nanoparticles as a drug delivery vehicle for MRI monitored magnetic targeting of brain tumors

Beata Chertok, Bradford A Moffat, Allan E David, Faquan Yu, Christian Bergemann, Brian D Ross, Victor C Yang

Journal article  |  2008  |  Biomaterials

Magnetization transfer effects on the efficiency of flow-driven adiabatic fast passage inversion of arterial blood

Luis Hernandez-Garcia, David P Lewis, Bradford Moffat, Craig A Branch

Journal article  |  2007  |  NMR in Biomedicine

An Imaging biomarker of early treatment response in prostate cancer that has metastasized to the bone

Kuei C Lee, Sudha Sud, Charles R Meyer, Bradford A Moffat, Thomas L Chenevert, Alnawaz Rehemtulla, Kenneth J Pienta, Brian D Ross

Journal article  |  2007  |  Cancer Research

Prospective early response imaging biomarker for neoadjuvant breast cancer chemotherapy

Kutei C Lee, Bradford A Moffat, Anne F Schott, Rachel Layman, Steven Ellingworth, Rebecca Juliar, Amjad P Khan, Mark Helvie, Charles R Meyer, Thomas L Chenevert, Alnawaz Rehemtulla, Brian D Ross

Journal article  |  2007  |  Clinical Cancer Research

Vascular targeted nanoparticles for imaging and treatment of brain tumors

G Ramachandra Reddy, Mahaveer S Bhojani, Patrick McConville, Jonathan Moody, Bradford A Moffat, Daniel E Hall, Gwangseong Kim, Yong-Eun L Koo, Michael J Woolliscroft, James V Sugai, Timothy D Johnson, Martin A Philbert, Raoul Kopelman, Alnawaz Rehemtulla, Brian D Ross

Journal article  |  2006  |  Clinical Cancer Research

Assessment of the functional diffusion map (fDM) as an imaging biomarker for early stratification of glioma clinical response.

BD Ross, DA Hamstra, TL Chenevert, BA Moffat, TD Johnson, C Tsein, CR Meyer, S Mukherji, L Junck, A Rehemtulla, TS Lawrence

Conference Proceedings  |  2006  |  JOURNAL OF CLINICAL ONCOLOGY

Dynamic Imaging of emerging resistance during cancer therapy

Kuei C Lee, Daniel E Hall, Benjamin A Hoff, Bradford A Moffat, Surabhi Sharma, Thomas L Chenevert, Charles R Meyer, Wilbur R Leopold, Timothy D Johnson, Richard V Mazurchuk, Alnawaz Rehemtulla, Brian D Ross

Journal article  |  2006  |  Cancer Research

Validation of functional diffusion mapping as a biomarker for early prediction of cancer treatment response

Bradford A Moffat, Kuei C Lee, Daniel E Hall, Daniel A Hamstra, Charles Meyer, Timothy D Johnson, Thomas L Chenevert, Alnawaz Rehemtulla, Brian D Ross

Conference Proceedings  |  2006  |  CANCER RESEARCH

Non-invasive bioluminescence imaging of apoptosis detects 5-FU enhanced TRAIL sensitivity in vivo

Kuei C Lee, Amjad P Khan, Mahaveer S Bhojani, Bharathi Laxman, Daniel E Hall, Daniel A Hamstra, Bradford A Moffat, Brian D Ross, Alnawaz Rehemtulla

Conference Proceedings  |  2006  |  CANCER RESEARCH

The functional diffusion map: An imaging biomarker for the early prediction of cancer treatment outcome

Bradford A Moffat, Thomas L Chenevert, Charles R Meyer, Paul E Mckeever, Daniel E Hall, Benjamin A Hoff, Timothy D Johnson, Alnawaz Rehemtulla, Brian D Ross

Journal article  |  2006  |  NeoPlasia

Inhibition of vascular endothelial growth factor (VEGF)-A causes a paradoxical increase in tumor blood flow and up-regulation of VEGF-D

BA Moffat, M Chen, MST Kariaapper, DA Hamstra, DE Hall, J Stojanovska, TD Johnson, M Blaivas, M Kumar, TL Chenevert, A Rehemtulla, BD Ross

Journal article  |  2006  |  Clinical Cancer Research

A methodology for registration of a histological slide and in vivo MRI volume based on optimizing mutual information

Charles R Meyer, Bradford A Moffat, Kyle K Kuszpit, Peyton L Bland, Paul E Mckeever, Timothy D Johnson, Thomas L Chenevert, Alnawaz Rehemtulla, Brian D Ross

Journal article  |  2006  |  Molecular Imaging

Fusion of the HSV-1 tegument protein vp22 to cytosine deaminase confers enhanced bystander effect and increased therapeutic benefit

KC Lee, DA Hamstra, S Bullarayasamudram, MS Bhojani, BA Moffat, KJ Dornfeld, BD Ross, A Rehemtulla

Journal article  |  2006  |  Gene Therapy

Evaluation of the functional diffusion map as an early biomarker of time-to-progression and overall survival in high-grade glioma

DA Hamstra, TL Chenevert, BA Moffat, TD Johnson, CR Meyer, SK Mukherji, DJ Quint, SS Gebarski, XY Fan, CI Tsien, TS Lawrence, L Junck, A Rehemtulla, BD Ross

Journal article  |  2005  |  Proceedings of the National Academy of Sciences of the United States of America

High-throughput magnetic resonance imaging in mice for phenotyping and therapeutic evaluation

P McConville, JB Moody, BA Moffat

Journal article  |  2005  |  Current Opinion in Chemical Biology

Intratumoral injection of BCNU in ethanol (DTI-015) results in enhanced delivery to tumor - a pharmacokinetic study

DA Hamstra, BA Moffat, DE Hall, JM Young, TJ Desmond, J Carter, D Pietronigro, KA Frey, A Rehemtulla, BD Ross

Journal article  |  2005  |  Journal of Neuro-Oncology

Quantification of early brain tumor therapeutic response using functional diffusion maps

BD Ross, BA Moffat, TL Chenevert, TS Lawrence, CR Meyer, TD Johnson, L Junk, A Rehemtulla

Conference Proceedings  |  2005  |  NEURO-ONCOLOGY

Diffusion MRI May Help Earlier Prediction of Response to Chemotherapy of Brain Tumors

B Moffat, T Chenevert, T Lawrence, C Meyer, T Johnson, Q Dong, C Tsien, S Mukherji, D Quint, S Gebarski, P Robertson, L Junck, A Rehemtulla

Journal article  |  2005  |  Cancer Biology and Therapy

Multifunctional nanoparticle platforms for in vivo MRI enhancement and photodynamic therapy of a rat brain cancer

R Kopelman, YEL Koo, M Philbert, BA Moffat, GR Reddy, P McConville, DE Hall, TL Chenevert, MS Bhojani, SM Buck, A Rehemtulla, BD Ross

Journal article  |  2005  |  Journal of Magnetism and Magnetic Materials

Functional diffusion map: A noninvasive MR1 biomarker for early stratification of clinical brain tumor response

BA Moffat, TL Chenevert, TS Lawrence, CR Meyer, TD Johnson, Q Dong, C Tsien, S Mukherji, DJ Quint, SS Gebarski, PL Robertson, LR Junck, A Rehemtulla, BD Ross

Journal article  |  2005  |  Proceedings of the National Academy of Sciences of the United States of America

Continuous arterial spin labeling using a train of adiabatic inversion pulses

BA Moffat, TL Chenevert, DE Hall, A Rehemtulla, BD Ross

Journal article  |  2005  |  Journal of Magnetic Resonance Imaging

Evaluation of the functional diffusion map (fDM) as an early biomarker of TTP and OS in high grade glioma

DA Hamstra, TL Chenevert, BA Moffat, TD Johnson, CR Meyer, C Tsien, TS Lawrence, LR Junck, A Rehemtulla, BD Ross

Conference Proceedings  |  2005  |  International Journal of Radiation Oncology*Biology*Physics

Diffusion MR imaging in adult neoplasia.

B MOFFAT, TLC Chenevert, BDR Ross

Book Chapter  |  2005

Development of a syngeneic rat brain tumor model expressing EGFRvIII and its use for molecular targeting studies with monoclonal antibody L8A4

WL Yang, RF Barth, G Wu, LJ Ciesielski, RA Fenstermaker, BA Moffat, BD Ross, CJ Wikstrand

Journal article  |  2005  |  Clinical Cancer Research

Diffusion imaging for evaluation of tumor therapies in preclinical animal models

BA Moffat, DE Hall, J Stojanovska, PJ McConville, JB Moody, TL Chenevert, A Rehemtulla, BD Ross

Journal article  |  2004  |  Magnetic Resonance Materials in Physics, Biology and Medicine

Therapeutic efficacy of DTI-015 using diffusion magnetic resonance imaging as an early surrogate marker

DE Hall, BA Moffat, J Stojanovska, TD Johnson, ZL Li, DA Hamstra, A Rehemtulla, TL Chenevert, J Carter, D Pietronigro, BD Ross

Journal article  |  2004  |  Clinical Cancer Research

The use of F-19 spectroscopy and diffusion-weighted MRI to evaluate differences in gene-dependent enzyme prodrug therapies

DA Hamstra, KC Lee, JM Tychewicz, VD Schepkin, BA Moffat, M Chen, KJ Dornfeld, TS Lawrence, TL Chenevert, BD Ross, JT Gelovani, A Rehemtulla

Journal article  |  2004  |  Molecular Therapy

Use of Magnetic Resonance Imaging (MRI) for evaluation treatment response.

BDR Ross, PM McConville, TLC Chenevert, B MOFFAT, AR Rehemtulla

Book Chapter  |  2004

A novel polyacrylamide magnetic nanoparticle contrast agent for molecular imaging using MRI.

Bradford A Moffat, G Ramachandra Reddy, Patrick McConville, Daniel E Hall, Thomas L Chenevert, Raoul R Kopelman, Martin Philbert, Ralph Weissleder, Alnawaz Rehemtulla, Brian D Ross

Journal article  |  2003  |  Molecular Imaging

A novel polyacrylamide superparamagnetic iron oxide nanoparticle platform is described which has been synthetically prepared such ..

Evaluation of cancer therapy using diffusion magnetic resonance imaging

BD Ross, BA Moffat, TS Lawrence, SK Mukherji, SS Gebarski, DJ Quint, TD Johnson, L Junck, PL Robertson, KM Muraszko, Q Dong, CR Meyer, PH Bland, P McConville, HR Geng, A Rehemtulla, TL Chenevert

Journal article  |  2003  |  Molecular Cancer Therapeutics

Age-related changes of the refractive index of the crystalline lens - Response

JM Pope, DA Atchison, BA Moffat

Journal article  |  2002  |  Vision Research

Age-related changes of the refractive index of the crystalline lens

RA Schachar

Journal article  |  2002  |  Vision Research

Diffusion MRI: a new strategy for assessment of cancer therapeutic efficacy.

Thomas L Chenevert, Charles R Meyer, Bradford A Moffat, Alnawaz Rehemtulla, Suresh K Mukherji, Stephen S Gebarski, Douglas J Quint, Patricia L Robertson, Theodore S Lawrence, Larry Junck, Jeremy M Taylor, Timothy D Johnson, Qian Dong, Karin M Muraszko, James A Brunberg, Brian D Ross

Journal article  |  2002  |  Molecular Imaging

The use of anatomical imaging in clinical oncology practice traditionally relies on comparison of patient scans acquired before an..

Age-related changes in refractive index distribution and power of the human lens as measured by magnetic resonance micro-imaging in vitro

BA Moffat, DA Atchison, JM Pope

Journal article  |  2002  |  Vision Research

Anisotropic water transport in the human eye lens studied by diffusion tensor NMR micro-imaging

BA Moffat, JM Pope

Journal article  |  2002  |  Experimental Eye Research

The emerging role of molecular imaging for evaluating cancer therapy

BD Ross, A Rehemtulla, TL Chenevert, B Moffat

Journal article  |  2002  |  BRITISH JOURNAL OF CANCER

Explanation of the lens paradox

BA Moffat, DA Atchison, JM Pope

Journal article  |  2002  |  Optometry and Vision Science

The interpretation of multi-exponential water proton transverse relaxation in the human and porcine eye lens

BA Moffat, JM Pope

Journal article  |  2002  |  Magnetic Resonance Imaging

Age-related changes in the kinetics of water transport in normal human lenses

BA Moffat, KA Landman, RJW Truscott, MHJ Sweeney, JM Pope

Journal article  |  1999  |  Experimental Eye Research

Systematic review protocol: Quantitative susceptibility mapping of brain iron accumulation in neurodegenerative diseases.

Parsa Ravanfar, Samantha Loi, Tamsyn Van Rheenen, Ashley Bush, Patricia Desmond, Vanessa Cropley, Bradford Moffat, Dennis Velakoulis, Christos Pantelis

Journal article

Iron has been found to play an important role in neurodegeneration. Quantitative susceptibility mapping (QSM) is a relatively new,..

Application of NMR Micro-imaging to the Study of Water Transport in Eye Lenses

BA Moffat, RJW Truscott, MHJ Sweeney, JM Pope

Book Chapter