Bradford Moffat

Study protocol for a phase II randomised, double-blind, placebo-controlled trial of perampanel as an antiepileptogenic treatment following acute stroke.

John-Paul Nicolo, Zhibin Chen, Bradford Moffat, David K Wright, Benjamin Sinclair, Rebecca Glarin, Andrew Neal, Vincent Thijs, Udaya Seneviratne, Bernard Yan, Geoffrey Cloud, Terence J O'Brien, Patrick Kwan

Journal article  |  2021  |  BMJ Open

INTRODUCTION: Stroke is a common cause of epilepsy that may be mediated via glutamate dysregulation. There is currently no evidenc..

7T Magnetic Resonance Imaging Quantification of Brain Glutamate in Acute Ischaemic Stroke

John-Paul Nicolo, Bradford Moffat, David K Wright, Benjamin Sinclair, Andrew Neal, Elaine Lui, Patricia Desmond, Rebecca Glarin, Kathryn A Davis, Ravinder Reddy, Bernard Yan, Terence J O'Brien, Patrick Kwan

Journal article  |  2021  |  Journal of stroke

Systematic Review: Quantitative Susceptibility Mapping (QSM) of Brain Iron Profile in Neurodegenerative Diseases

Parsa Ravanfar, Samantha M Loi, Warda T Syeda, Tamsyn E Van Rheenen, Ashley I Bush, Patricia Desmond, Vanessa L Cropley, Darius JR Lane, Carlos M Opazo, Bradford A Moffat, Dennis Velakoulis, Christos Pantelis

Journal article  |  2021  |  FRONTIERS IN NEUROSCIENCE

Iron has been increasingly implicated in the pathology of neurodegenerative diseases. In the past decade, development of the new m..

Ultra-High Field Magnetic Resonance Imaging of the Retrobulbar Optic Nerve, Subarachnoid Space, and Optic Nerve Sheath in Emmetropic and Myopic Eyes

Bao N Nguyen, Jon O Cleary, Rebecca Glarin, Scott C Kolbe, Bradford A Moffat, Roger J Ordidge, Bang V Bui, Allison M McKendrick

Journal article  |  2021  |  Translational Vision Science & Technology

Purpose: We aimed to image the optic nerve, subarachnoid space and optic nerve sheath in emmetropes and myopes ultra-high field (7..

MR-EYE: High-Resolution MRI of the Human Eye and Orbit at Ultrahigh Field (7T)

Rebecca K Glarin, Bao N Nguyen, Jon O Cleary, Scott C Kolbe, Roger J Ordidge, Bang Bui, Allison M McKendrick, Bradford A Moffat

Journal article  |  2021  |  Magnetic Resonance Imaging Clinics of North America

Key points • Dedicated eye imaging can be implemented at 7T to acquire high-resolution, high contrast-to-noise, and high signal-to..

QSMART: Quantitative Susceptibility Mapping Artifact Reduction Technique

Negin Yaghmaie, Warda Syeda, Chengchuan Wu, Yicheng Zhang, Tracy D Zhang, Emma L Burrows, Amy Brodtmann, Bradford A Moffat, David K Wright, Rebecca Glarin, Scott Kolbe, Leigh Johnston

Journal article  |  2021  |  NeuroImage

PURPOSE: Quantitative susceptibility mapping (QSM) is a novel MR technique that allows mapping of tissue susceptibility values fro..

Resting-state functional connectivity and quantitation of glutamate and GABA of the PCC/precuneus by magnetic resonance spectroscopy at 7T in healthy individuals

Ofer M Gonen, Bradford A Moffat, Patrick Kwan, Terence J O'Brien, Patricia M Desmond, Elaine Lui

Journal article  |  2020  |  PLOS ONE

The default mode network (DMN) is the main large-scale network of the resting brain and the PCC/precuneus is a major hub of this n..

xQSM: quantitative susceptibility mapping with octave convolutional and noise-regularized neural networks

Yang Gao, Xuanyu Zhu, Bradford A Moffat, Rebecca Glarin, Alan H Wilman, G Bruce Pike, Stuart Crozier, Feng Liu, Hongfu Sun

Journal article  |  2020  |  NMR IN BIOMEDICINE

Quantitative susceptibility mapping (QSM) provides a valuable MRI contrast mechanism that has demonstrated broad clinical applicat..

Ultra-high-field MRI using composite RF (STEP) pulses

Roger Ordidge, Jon Cleary, Rebecca Glarin, Yasmin Blunck, Shawna Farquharson, Brad Moffat

Journal article  |  2020  |  NMR IN BIOMEDICINE

Ultra-high field MRI offers many opportunities to expand the applications of MRI. In order for this to be realized, the technical ..

Seven-tesla quantitative magnetic resonance spectroscopy of glutamate, gamma-aminobutyric acid, and glutathione in the posterior cingulate cortex/precuneus in patients with epilepsy

Ofer M Gonen, Bradford A Moffat, Patricia M Desmond, Elaine Lui, Patrick Kwan, Terence J O'Brien

Journal article  |  2020  |  EPILEPSIA

OBJECTIVE: The posterior cingulate cortex (PCC)/precuneus is a key hub of the default mode network, whose function is known to be ..