Bradford Moffat

Systematic Review: Quantitative Susceptibility Mapping (QSM) of Brain Iron Profile in Neurodegenerative Diseases

Parsa Ravanfar, Samantha M Loi, Warda T Syeda, Tamsyn E Van Rheenen, Ashley I Bush, Patricia Desmond, Vanessa L Cropley, Darius JR Lane, Carlos M Opazo, Bradford A Moffat, Dennis Velakoulis, Christos Pantelis

Journal article  |  2021  |  Frontiers in Neuroscience

Iron has been increasingly implicated in the pathology of neurodegenerative diseases. In the past decade, development of the new m..

Ultra-High Field Magnetic Resonance Imaging of the Retrobulbar Optic Nerve, Subarachnoid Space, and Optic Nerve Sheath in Emmetropic and Myopic Eyes

Bao N Nguyen, Jon O Cleary, Rebecca Glarin, Scott C Kolbe, Bradford A Moffat, Roger J Ordidge, Bang V Bui, Allison M McKendrick

Journal article  |  2021  |  Translational Vision Science and Technology

Purpose: We aimed to image the optic nerve, subarachnoid space and optic nerve sheath in emmetropes and myopes ultra-high field (7..

MR-EYE: High-Resolution MRI of the Human Eye and Orbit at Ultrahigh Field (7T)

Rebecca K Glarin, Bao N Nguyen, Jon O Cleary, Scott C Kolbe, Roger J Ordidge, Bang Bui, Allison M McKendrick, Bradford A Moffat

Journal article  |  2021  |  Magnetic Resonance Imaging Clinics of North America

Key points • Dedicated eye imaging can be implemented at 7T to acquire high-resolution, high contrast-to-noise, and high signal-to..

QSMART: Quantitative Susceptibility Mapping Artifact Reduction Technique

Negin Yaghmaie, Warda Syeda, Chengchuan Wu, Yicheng Zhang, Tracy D Zhang, Emma L Burrows, Amy Brodtmann, Bradford A Moffat, David K Wright, Rebecca Glarin, Scott Kolbe, Leigh Johnston

Journal article  |  2021  |  NeuroImage

PURPOSE: Quantitative susceptibility mapping (QSM) is a novel MR technique that allows mapping of tissue susceptibility values fro..

Resting-state functional connectivity and quantitation of glutamate and GABA of the PCC/precuneus by magnetic resonance spectroscopy at 7T in healthy individuals

Ofer M Gonen, Bradford A Moffat, Patrick Kwan, Terence J O'Brien, Patricia M Desmond, Elaine Lui

Journal article  |  2020  |  PLoS One

The default mode network (DMN) is the main large-scale network of the resting brain and the PCC/precuneus is a major hub of this n..

xQSM: quantitative susceptibility mapping with octave convolutional and noise-regularized neural networks

Yang Gao, Xuanyu Zhu, Bradford A Moffat, Rebecca Glarin, Alan H Wilman, G Bruce Pike, Stuart Crozier, Feng Liu, Hongfu Sun

Journal article  |  2020  |  NMR in Biomedicine

Quantitative susceptibility mapping (QSM) provides a valuable MRI contrast mechanism that has demonstrated broad clinical applicat..

Ultra-high-field MRI using composite RF (STEP) pulses

Roger Ordidge, Jon Cleary, Rebecca Glarin, Yasmin Blunck, Shawna Farquharson, Brad Moffat

Journal article  |  2020  |  NMR in Biomedicine

Ultra-high field MRI offers many opportunities to expand the applications of MRI. In order for this to be realized, the technical ..

Seven-tesla quantitative magnetic resonance spectroscopy of glutamate, gamma-aminobutyric acid, and glutathione in the posterior cingulate cortex/precuneus in patients with epilepsy

Ofer M Gonen, Bradford A Moffat, Patricia M Desmond, Elaine Lui, Patrick Kwan, Terence J O'Brien

Journal article  |  2020  |  Epilepsia

OBJECTIVE: The posterior cingulate cortex (PCC)/precuneus is a key hub of the default mode network, whose function is known to be ..

Reproducibility of Glutamate, Glutathione, and GABA Measurementsin vivoby Single-Voxel STEAM Magnetic Resonance Spectroscopy at 7-Tesla in Healthy Individuals

Ofer M Gonen, Bradford A Moffat, Patrick Kwan, Terence J O'Brien, Patricia M Desmond, Elaine Lui

Journal article  |  2020  |  Frontiers in Neuroscience

Background and Purpose: Derangements in brain glutamate, glutathione, and γ-amino butyric acid (GABA) are implicated in a range of..

Distinct Neural Correlates Underlie Inhibitory Mechanisms of Motor Inhibition and Motor Imagery Restraint

PE Yoo, TJ Oxley, MA Hagan, S John, SM Ronayne, GS Rind, AM Brinded, NL Opie, BA Moffat, YT Wong

Journal article  |  2020  |  Frontiers in Behavioral Neuroscience

There is evidence to suggest that motor execution and motor imagery both involve planning and execution of the same motor plan, ho..