Bradford Moffat

Seven-tesla quantitative magnetic resonance spectroscopy of glutamate, gamma-aminobutyric acid, and glutathione in the posterior cingulate cortex/precuneus in patients with epilepsy

Ofer M Gonen, Bradford A Moffat, Patricia M Desmond, Elaine Lui, Patrick Kwan, Terence J O'Brien

Journal article  |  2020  |  Epilepsia

OBJECTIVE: The posterior cingulate cortex (PCC)/precuneus is a key hub of the default mode network, whose function is known to be ..

Reproducibility of Glutamate, Glutathione, and GABA Measurementsin vivoby Single-Voxel STEAM Magnetic Resonance Spectroscopy at 7-Tesla in Healthy Individuals

Ofer M Gonen, Bradford A Moffat, Patrick Kwan, Terence J O'Brien, Patricia M Desmond, Elaine Lui

Journal article  |  2020  |  Frontiers in Neuroscience

Background and Purpose: Derangements in brain glutamate, glutathione, and γ-amino butyric acid (GABA) are implicated in a range of..

Distinct Neural Correlates Underlie Inhibitory Mechanisms of Motor Inhibition and Motor Imagery Restraint

PE Yoo, TJ Oxley, MA Hagan, S John, SM Ronayne, GS Rind, AM Brinded, NL Opie, BA Moffat, YT Wong

Journal article  |  2020  |  Frontiers in Behavioral Neuroscience

There is evidence to suggest that motor execution and motor imagery both involve planning and execution of the same motor plan, ho..

OnabotulinumtoxinA treatment for MS-tremor modifies fMRI tremor response in central sensory-motor integration areas

Frederique MC Boonstra, Andrew Evans, Gustavo Noffs, Thushara Perera, Vilija Jokubaitis, Jim Stankovich, Adam P Vogel, Bradford A Moffat, Helmut Butzkueven, Scott C Kolbe, Anneke van der Walt

Journal article  |  2020  |  Multiple Sclerosis and Related Disorders

BACKGROUND: Treatment of tremor in MS is an unmet need. OnabotulinumtoxinA (BoNT-A) has shown promising results; however, little i..

Functional neuroplasticity in response to cerebello-thalamic injury underpins the clinical presentation of tremor in multiple sclerosis.

Frederique Mc Boonstra, Gustavo Noffs, Thushara Perera, Vilija G Jokubaitis, Adam P Vogel, Bradford A Moffat, Helmut Butzkueven, Andrew Evans, Anneke van der Walt, Scott C Kolbe

Journal article  |  2020  |  Multiple Sclerosis Journal

BACKGROUND: Tremor is present in almost half of multiple sclerosis (MS) patients. The lack of understanding of its pathophysiology..

Extracting more for less: multi-echo MP2RAGE for simultaneous T-1-weighted imaging, T-1 mapping, R-2* mapping, SWI, and QSM from a single acquisition

Hongfu Sun, Jon O Cleary, Rebecca Glarin, Scott C Kolbe, Roger J Ordidge, Bradford A Moffat, G Bruce Pike

Journal article  |  2020  |  Magnetic Resonance in Medicine

Compressed sensing effects on quantitative analysis of undersampled human brain sodium MRI

Yasmin Blunck, Scott C Kolbe, Bradford A Moffat, Roger J Ordidge, Jon O Cleary, Leigh A Johnston

Journal article  |  2020  |  Magnetic Resonance in Medicine

Purpose The clinical application of sodium MRI is hampered due to relatively low image quality and associated long acquisition tim..

Systematic review protocol: Quantitative susceptibility mapping of brain iron accumulation in neurodegenerative diseases

Parsa Ravanfar, Samantha Loi, Tamsyn Van Rheenen, Ashley Bush, Patricia Desmond, Vanessa Cropley, Bradford Moffat, Dennis Velakoulis, Christos Pantelis

Journal article  |  2020

Abstract Iron has been found to play an important role in neurodegeneration. Quantitative susceptibility mapping (QSM) is a relati..

Normative retrobulbar measurements of the optic nerve using ultra high field magnetic resonance imaging

Bao N Nguyen, Jon O Cleary, Rebecca Glarin, Scott C Kolbe, Bradford A Moffat, Roger J Ordidge, Bang V Bui, Allison M McKendrick

Conference Proceedings  |  2019  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Phantom measurement predicts the impact of image reconstruction on Florbetapir SUVR quantification

Robert Williams, Leigh Johnston, Vincent Dore, Graeme O'Keefe, Jason Callahan, Zhihan Xu, Shuning Zheng, Bradford Moffat, Colin Masters, Christopher Rowe

Conference Proceedings  |  2019  |  JOURNAL OF NUCLEAR MEDICINE