Raymond Wong

Sustained subcutaneous delivery of secretome of human cardiac stem cells promotes cardiac repair following myocardial infarction

Andrew R Kompa, David W Greening, Anne M Kong, Paul J McMillan, Haoyun Fang, Ritika Saxena, Raymond CB Wong, Jarmon G Lees, Priyadharshini Sivakumaran, Andrew E Newcomb, Bakhos A Tannous, Cameron Kos, Lina Mariana, Thomas Loudovaris, Derek J Hausenloy, Shiang Y Lim

Journal article  |  2021  |  CARDIOVASCULAR RESEARCH

AIMS: To establish pre-clinical proof of concept that sustained subcutaneous delivery of the secretome of human cardiac stem cells..

New Technologies to Study Functional Genomics of Age-Related Macular Degeneration

Tu Nguyen, Daniel Urrutia-Cabrera, Roxanne Hsiang-Chi Liou, Chi D Luu, Robyn Guymer, Raymond Ching-Bong Wong

Journal article  |  2021  |  FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY

Age-related macular degeneration (AMD) is the most common cause of irreversible vision loss in people over 50 years old in develop..

Using single cell transcriptomics to study the complexity of human retina

Daniel Urrutia-Cabrera, Raymond Ching-Bong Wong

Journal article  |  2020  |  NEURAL REGENERATION RESEARCH

Comparison of CRISPR/Cas Endonucleases forin vivoRetinal Gene Editing

Fan Li, Kristof Wing, Jiang-Hui Wang, Chi D Luu, James A Bender, Jinying Chen, Qi Wang, Qinyi Lu, Minh Thuan Nguyen Tran, Kaylene M Young, Raymond CB Wong, Alice Pebay, Anthony L Cook, Sandy SC Hung, Guei-Sheung Liu, Alex W Hewitt

Journal article  |  2020  |  FRONTIERS IN CELLULAR NEUROSCIENCE

CRISPR/Cas has opened the prospect of direct gene correction therapy for some inherited retinal diseases. Previous work has demons..

Neuronal Reprogramming for Tissue Repair and Neuroregeneration

Roxanne Hsiang-Chi Liou, Thomas L Edwards, Keith R Martin, Raymond Ching-Bong Wong

Journal article  |  2020  |  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Stem cell and cell reprogramming technology represent a rapidly growing field in regenerative medicine. A number of novel neural r..

Towards retinal regeneration: Reprogramming retinal glial cells into photoreceptors using CRISPRa

Raymond Wong, Tu Nguyen, Lyujie Fang, Sam Lukowski, Camden Lo, Sandy Hung, Chi D Luu, Mark C Gillies, Alex W Hewitt

Conference Proceedings  |  2020  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

THE RELATIONSHIP BETWEEN OFF-SITE ON-CALL SHIFTS AND SLEEP, MOOD AND VIGILANCE AMONG DOCTORS - DOCTORS ON-CALL (DOC) STUDY

Raymond Wong, Melinda Jackson, Christopher Worsnop

Conference Proceedings  |  2020  |  INTERNAL MEDICINE JOURNAL

Differentiation of Retinal Glial Cells From Human Embryonic Stem Cells by Promoting the Notch Signaling Pathway

Sook Hyun Chung, Weiyong Shen, Kathryn C Davidson, Alice Pebay, Raymond CB Wong, Belinda Yau, Mark Gillies

Journal article  |  2019  |  FRONTIERS IN CELLULAR NEUROSCIENCE

Dysfunction of retinal glial cells, particularly Müller cells, has been implicated in several retinal diseases. Despite their impo..

Utility of Self-Destructing CRISPR/Cas Constructs for Targeted Gene Editing in the Retina

Fan Li, Sandy SC Hung, Mohd Khairul Nizam Mohd Khalid, Jiang-Hui Wang, Vicki Chrysostomou, Vickie HY Wong, Vikrant Singh, Kristof Wing, Leilei Tu, James A Bender, Alice Pebay, Anna E King, Anthony L Cook, Raymond CB Wong, Bang Bui, Alex W Hewitt, Guei-Sheung Liu

Journal article  |  2019  |  HUMAN GENE THERAPY

Safe delivery of CRISPR/Cas endonucleases remains one of the major barriers to the widespread application of in vivo genome editin..

A single-cell transcriptome atlas of the adult human retina

Samuel W Lukowski, Camden Y Lo, Alexei A Sharov, Quan Nguyen, Lyujie Fang, Sandy SC Hung, Ling Zhu, Ting Zhang, Ulrike Grunert, Tu Nguyen, Anne Senabouth, Jafar S Jabbari, Emily Welby, Jane C Sowden, Hayley S Waugh, Adrienne Mackey, Graeme Pollock, Trevor D Lamb, Peng-Yuan Wang, Alex W Hewitt, et al.

Journal article  |  2019  |  EMBO JOURNAL

The retina is a specialized neural tissue that senses light and initiates image processing. Although the functional organization o..