Stephen Fox

Systematic review of NTRK 1/2/3 fusion prevalence pan-cancer and across solid tumours.

Sophie O'Haire, Fanny Franchini, Yoon-Jung Kang, Julia Steinberg, Karen Canfell, Jayesh Desai, Stephen Fox, Maarten IJzerman

Journal article  |  2023  |  Sci Rep

NTRK gene fusions are rare somatic mutations found across cancer types with promising targeted therapies emerging. Healthcare syst..

The impact of coding germline variants on contralateral breast cancer risk and survival.

Anna Morra, Nasim Mavaddat, Taru A Muranen, Thomas U Ahearn, Jamie Allen, Irene L Andrulis, Päivi Auvinen, Heiko Becher, Sabine Behrens, Carl Blomqvist, Stig E Bojesen, Manjeet K Bolla, Hiltrud Brauch, Nicola J Camp, Sara Carvalho, Jose E Castelao, Melissa H Cessna, Jenny Chang-Claude, Georgia Chenevix-Trench, undefined NBCS Collaborators, et al.

Journal article  |  2023  |  Am J Hum Genet

Evidence linking coding germline variants in breast cancer (BC)-susceptibility genes other than BRCA1, BRCA2, and CHEK2 with contr..

Australian Genomics: Outcomes of a 5-year national program to accelerate the integration of genomics in healthcare.

Zornitza Stark, Tiffany Boughtwood, Matilda Haas, Jeffrey Braithwaite, Clara L Gaff, Ilias Goranitis, Amanda B Spurdle, David P Hansen, Oliver Hofmann, Nigel Laing, Sylvia Metcalfe, Ainsley J Newson, Hamish S Scott, Natalie Thorne, Robyn L Ward, Marcel E Dinger, Stephanie Best, Janet C Long, Sean M Grimmond, John Pearson, et al.

Journal article  |  2023  |  Am J Hum Genet

Australian Genomics is a national collaborative partnership of more than 100 organizations piloting a whole-of-system approach to ..

Homologous Recombination Repair Deficiency: An Overview for Pathologists.

Kenneth D Doig, Andrew P Fellowes, Stephen B Fox

Journal article  |  2023  |  Mod Pathol

The repair of DNA double-stranded breaks relies on the homologous recombination repair pathway and is critical to cell function. H..

Prognostic and Predictive Biomarkers in Familial Breast Cancer.

Siddhartha Deb, Anannya Chakrabarti, Stephen B Fox

Journal article  |  2023  |  Cancers (Basel)

Large numbers of breast cancers arise within a familial context, either with known inherited germline mutations largely within DNA..

Identification errors in medical research: privacy at all costs?

James A Rickard, Toni-Maree Rogers, David A Westerman, Cathy Carolan, Stephen B Fox

Journal article  |  2023  |  Pathology

Phyllodes tumour evidence gaps mapped from the 5th edition of the WHO classification of tumours of the breast

Nur Diyana Md Nasir, Valerie CY Koh, Ian A Cree, Blanca II Ruiz, Javier Del Aguila, Subasri Armon, Stephen B Fox, Sunil R Lakhani, Puay Hoon Tan

Journal article  |  2023  |  HISTOPATHOLOGY

AIMS: Breast phyllodes tumours (PTs) are a rare subset of fibroepithelial neoplasms categorised into benign, borderline, and malig..

A Phase II Trial of Guadecitabine in Children and Adults with SDH-Deficient GIST, Pheochromocytoma, Paraganglioma, and HLRCC-Associated Renal Cell Carcinoma.

John A Ligon, R Taylor Sundby, Mary F Wedekind, Fernanda I Arnaldez, Jaydira Del Rivero, Lori Wiener, Ramaprasad Srinivasan, Melissa Spencer, Amanda Carbonell, Haiyan Lei, John Shern, Seth M Steinberg, William D Figg, Cody J Peer, Sara Zimmerman, Josquin Moraly, Xia Xu, Stephen Fox, King Chan, Michael I Barbato, et al.

Journal article  |  2023  |  Clin Cancer Res

PURPOSE: Succinate dehydrogenase (dSDH)-deficient tumors, including pheochromocytoma/paraganglioma, hereditary leiomyomatosis and ..

The Ring Study: an international comparison of PD-L1 diagnostic assays and their interpretation in non-small cell lung cancer, head and neck squamous cell cancer and urothelial cancer

Sung-liang Yu, Yi-jing Hsiao, Wendy A Cooper, Yoon-la Choi, ALEJANDRO Aviles-salas, Teh-ying Chou, RENATA Coudry, Grigory A Raskin, Stephen B Fox, Chao-cheng Huang, Yoon kyung Jeon, Young-hyeh Ko, Wen-hui Ku, Ghee-young Kwon, CONNULL Leslie, Mei-chun Lin, Pei-jen Lou, CRISTOVAM Scapulatempo-neto, Saulo mendoza Ramirez, NIKITA Savelov, et al.

Journal article  |  2023  |  PATHOLOGY

PD-L1 immunohistochemistry has been approved as a diagnostic assay for immunotherapy. However, an international comparison across ..

Identifying recurrences and metastasis after ductal carcinoma in situ (DCIS) of the breast

Ruwangi Udayasiri, Tongtong Luo, Kylie L Gorringe, Stephen B Fox

Journal article  |  2023  |  HISTOPATHOLOGY

Ductal carcinoma in situ (DCIS) of the breast is a non-invasive tumour that has the potential to progress to invasive ductal carci..