James Bell

Using machine learning to ace cardiovascular risk tests.

James R Bell, Gemma A Figtree, Grant R Drummond

Journal article  |  2020  |  Cardiovasc Res

Epicardial Adipose Tissue Accumulation Confers Atrial Conduction Abnormality

Chrishan J Nalliah, James R Bell, Antonia JA Raaijmakers, Helen M Waddell, Simon P Wells, Gabriel B Bernasochi, Magdalene K Montgomery, Simon Binny, Troy Watts, Subodh B Joshi, Elaine Lui, Choon Boon Sim, Marco Larobina, Michael O'Keefe, John Goldblatt, Alistair Royse, Geoffrey Lee, Enzo R Porrello, Matthew J Watt, Peter M Kistler, et al.

Journal article  |  2020  |  JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

BACKGROUND: Clinical studies have reported that epicardial adipose tissue (EpAT) accumulation associates with the progression of a..

A novel mass spectrometric methodology facilitates quantification of testosterone and progesterone, but not estrogens in cardiac and adipose tissues

Gabriel B Bernasochi, Thusitha TW Rupasinghe, James R Bell, Ute Roessner, Wah Chin Boon, Lea MD Delbridge

Conference Proceedings  |  2020  |  JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Cardiomyocyte functional screening: interrogating comparative electrophysiology of high-throughput model cell systems

Simon P Wells, Helen M Waddell, Choon Boon Sim, Shiang Y Lim, Gabriel B Bernasochi, Davor Pavlovic, Paulus Kirchhof, Enzo R Porrello, Lea MD Delbridge, James R Bell

Journal article  |  2019  |  AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Cardiac arrhythmias of both atrial and ventricular origin are an important feature of cardiovascular disease. Novel antiarrhythmic..

Impact of Estrogens on the Regulation of White, Beige, and Brown Adipose Tissue Depots

Gabriel B Bernasochi, James R Bell, Evan R Simpson, Lea MD Delbridge, Wah Chin Boon

Journal article  |  2019  |  COMPREHENSIVE PHYSIOLOGY

As adipose tissue depots are active endocrine organs, they secrete a variety of hormones (including estrogens from white adipose) ..

The myocardium and sex steroid hormone influences

Gabriel B Bernasochi, Wah Chin Boon, Lea Md Delbridge, James R Bell

Journal article  |  2018  |  CURRENT OPINION IN PHYSIOLOGY

Extensive evidence of sex steroid hormone influence on cardiac function and cardiopathology has been observed in both clinical and..

Cardiomyocyte Functional Etiology in Heart Failure With Preserved Ejection Fraction Is Distinctive-A New Preclinical Model

Claire L Curl, Vennetia R Danes, James R Bell, Antonia JA Raaijmakers, Wendy TK Ip, Chanchal Chandramouli, Tristan W Harding, Enzo R Porrello, Jeffrey R Erickson, Fadi J Charchar, Andrew R Kompa, Amanda J Edgley, David J Crossman, Christian Soeller, Kimberley M Mellor, Jonathan M Kalman, StephenB Harrap, Lea MD Delbridge

Journal article  |  2018  |  JOURNAL OF THE AMERICAN HEART ASSOCIATION

BACKGROUND: Among the growing numbers of patients with heart failure, up to one half have heart failure with preserved ejection fr..

Pericardial adipose and aromatase: A new translational target for aging, obesity and arrhythmogenesis?

Gabriel B Bernasochi, Wah Chin Boon, Claire L Curl, Upasna Varma, Salvatore Pepe, Marianne Tare, Laura J Parry, Evdokia Dimitriadis, Stephen B Harrap, Chrishan J Nalliah, Jonathan M Kalman, Lea MD Delbridge, James R Bell

Journal article  |  2017  |  JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

A correlation exists between the extent of pericardial adipose and atrial fibrillation (AF) risk, though the underlying mechanisms..

Experimental and Human Evidence for Lipocalin-2 (Neutrophil Gelatinase-Associated Lipocalin [NGAL]) in the Development of Cardiac Hypertrophy and heart failure

Francine Z Marques, Priscilla R Prestes, Sean G Byars, Scott C Ritchie, Peter Wurtz, Sheila K Patel, Scott A Booth, Indrajeetsinh Rana, Yosuke Minoda, Stuart P Berzins, Claire L Curl, James R Bell, Bryan Wai, Piyush M Srivastava, Antti J Kangas, Pasi Soininen, Saku Ruohonen, Mika Kahonen, Terho Lehtimaki, Emma Raitoharju, et al.

Journal article  |  2017  |  JOURNAL OF THE AMERICAN HEART ASSOCIATION

BACKGROUND: Cardiac hypertrophy increases the risk of developing heart failure and cardiovascular death. The neutrophil inflammato..

Insights into the role of maladaptive hexosamine biosynthesis and O-GlcNAcylation in development of diabetic cardiac complications

Cheng Xue Qin, Rochelle Sleaby, Amy J Davidoff, James R Bell, Miles J De Blasio, Leanne M Delbridge, John C Chatham, Rebecca H Ritchie

Journal article  |  2017  |  PHARMACOLOGICAL RESEARCH

Diabetes mellitus significantly increases the risk of heart failure, independent of coronary artery disease. The mechanisms implic..