Sheila Patel

Plasma ACE2 activity is persistently elevated following SARS-CoV-2 infection: implications for COVID-19 pathogenesis and consequences

Sheila Patel, Jennifer Juno, Wen Shi Lee, Kathleen Wragg, Mark Hogarth, Stephen Kent, Louise Burrell

Journal article  |  2020

COVID-19 causes persistent endothelial inflammation, lung and cardiovascular complications. SARS-CoV-2 utilises the catalytic site..

Impaired Retinal Microvascular Function Predicts Long-Term Adverse Events in Patients with Cardiovascular Disease.

James D Theuerle, Ali H Al-Fiadh, Fakir M Amirul Islam, Sheila K Patel, Louise M Burrell, Tien Yin Wong, Omar Farouque

Journal article  |  2020  |  Cardiovascular Research

AIMS: Endothelial dysfunction is a precursor to the development of symptomatic atherosclerosis. Retinal microvascular reactivity t..

Imbalance of the renin-angiotensin system may contribute to inflammation and fibrosis in IBD: a novel therapeutic target?

Mayur Garg, Simon G Royce, Chris Tikellis, Claire Shallue, Duygu Batu, Elena Velkoska, Louise M Burrell, Sheila K Patel, Lauren Beswick, Anvesh Jackson, Kaushali Britto, Matthew Lukies, Pavel Sluka, Hady Wardan, Yumiko Hirokawa, Chin Wee Tan, Maree Faux, Antony W Burgess, Patrick Hosking, Shaun Monagle, et al.

Journal article  |  2020  |  Gut

OBJECTIVE: We evaluated the influence of the renin-angiotensin system (RAS) on intestinal inflammation and fibrosis. DESIGN: Cultu..

Plasma ACE2 Activity Predicts Mortality in Aortic Stenosis and Is Associated With Severe Myocardial Fibrosis

Jay Ramchand, Sheila K Patel, Leighton G Kearney, George Matalanis, Omar Farouque, Piyush M Srivastava, Louise M Burrell

Journal article  |  2020  |  JACC: Cardiovascular Imaging

OBJECTIVES: This study investigated the relationship between plasma angiotensin-converting enzyme 2 (ACE2) activity levels and the..

Gamma-glutamyltransferase, arterial remodeling and prehypertension in a healthy population at low cardiometabolic risk

M Kozakova, A Gastaldelli, C Morizzo, K Højlund, PM Nilssson, E Ferrannini, RJ Heine, J Dekker, S de Rooij, G Nijpels, W Boorsma, A Kok, A Mitrakou, S Tournis, K Kyriakopoulou, P Thomakos, N Lalic, K Lalic, A Jotic, L Lukic, et al.

Journal article  |  2020  |  Journal of Human Hypertension

Plasma endothelin-1 and adrenomedullin are associated with coronary artery function and cardiovascular outcomes in humans

James Theuerle, Omar Farouque, Sheran Vasanthakumar, Sheila K Patel, Louise M Burrell, David J Clark, Ali H Al-Fiadh

Journal article  |  2019  |  International Journal of Cardiology

Development of Acute Decompensated Heart Failure Among Hospital Inpatients: Incidence, Causes and Outcomes

Luke D Plant, David McDonald Taylor, Thomas Worland, Arvind Puri, Antony Ugoni, Sheila K Patel, Douglas F Johnson, Louise M Burrell

Journal article  |  2019  |  Heart, Lung and Circulation

APOE epsilon 4 Carriers Show Delayed Recovery of Verbal Memory and Smaller Entorhinal Volume in the First Year After Ischemic Stroke

Emilio Werden, Mohamed Salah Khlif, Laura J Bird, Toby Cumming, Jennifer Bradshaw, Wasim Khan, Matthew Pase, Carolina Restrepo, Michele Veldsman, Natalia Egorova, Sheila K Patel, Elie Gottlieb, Amy Brodtmann

Journal article  |  2019  |  Journal of Alzheimer's Disease

CEREBRAL ATROPHY IN PATIENTS WITH TYPE 2 DIABETES AND LEFT VENTRICULAR HYPERTROPHY: PRELIMINARY DATA FROM THE DIABETES AND DEMENTIA (D2) STUDY

Sheila Patel, Sheila K Patel, Mohamed S Khlif, Jay Ramchand, Carolina Restrepo, Elise Harrison, Amanda Shanks, Emilio Werden, Piyush M Srivastava, Elif I Ekinci, Louise M Burrell, Amy Brodtmann

Conference Proceedings  |  2018  |  Journal of Hypertension

INVESTIGATION OF THE PEGUERO-LO PRESTI CRITERIA TO IMPROVE THE SENSITIVITY OF THE ELECTROCARDIOGRAM TO DIAGNOSE LEFT VENTRICULAR HYPERTROPHY IN PATIENTS WITH TYPE 2 DIABETES

Thalys Sampaio Rodrigues, Jay Ramchand, Bryan Wai, Piyush M Srivastava, Ronan O'Donnabhain, Sheila K Patel, Louise M Burrell

Conference Proceedings  |  2018  |  Journal of Hypertension