Sheila Patel

Retinal microvascular function predicts chronic kidney disease in patients with cardiovascular risk factors.

James D Theuerle, Ali H Al-Fiadh, Edmond Wong, Sheila K Patel, Gizem Ashraf, Thanh Nguyen, Tien Yin Wong, Francesco L Ierino, Louise M Burrell, Omar Farouque

Journal article  |  2021  |  Atherosclerosis

BACKGROUND AND AIMS: Endothelial dysfunction is a precursor to atherosclerosis and is implicated in the coexistence between cardio..

Angiotensin-Converting Enzyme 2 Activity Is Associated With Embolic Stroke of Undetermined Source

Jithin K Sajeev, Helen Dewey, Jonathan M Kalman, Bon Chou, Louise Roberts, Jennifer C Cooke, Anoop N Koshy, Sheila K Patel, Merryn Gould, Jeremy Ngoh, Louise M Burrell, Andrew W Teh

Journal article  |  2021  |  STROKE

[Figure: see text].

Impaired retinal microvascular function predicts long-term adverse events in patients with cardiovascular disease

James D Theuerle, Ali H Al-Fiadh, Fakir M Amirul Islam, Sheila K Patel, Louise M Burrell, Tien Yin Wong, Omar Farouque

Journal article  |  2021  |  CARDIOVASCULAR RESEARCH

AIMS: Endothelial dysfunction is a precursor to the development of symptomatic atherosclerosis. Retinal microvascular reactivity t..

Plasma ACE2 activity is persistently elevated following SARS-CoV-2 infection: implications for COVID-19 pathogenesis and consequences

Sheila K Patel, Jennifer A Juno, Wen Shi Lee, Kathleen M Wragg, P Mark Hogarth, Stephen J Kent, Louise M Burrell

Journal article  |  2021  |  EUROPEAN RESPIRATORY JOURNAL

Gamma-glutamyltransferase, arterial remodeling and prehypertension in a healthy population at low cardiometabolic risk.

Michaela Kozakova, Amalia Gastaldelli, Carmela Morizzo, Kurt Højlund, Peter M Nilssson, Ele Ferrannini, undefined RISC Investigators, Carlo Palombo

Journal article  |  2021  |  J Hum Hypertens

Plasma gamma-glutamyltransferase (GGT) was suggested to reflect the level of systemic oxidative stress. Oxidative stress induces c..

Comparison of brain atrophy and cognitive performance in individuals with low and high cardiovascular risk: Data from the Diabetes and Dementia (D2) Study

Carolina Restrepo, Emilio Werden, Rebecca Singleton, Mohamed Salah Khlif, Laura J Bird, Elif Ekinci, Richard MacIsaac, Piyush Srivastava, Sheila Patel, Louise Burrell, Amy Brodtmann

Conference Proceedings  |  2020  |  Alzheimer's & Dementia

Cognitive and imaging impacts of left ventricular hypertrophy in people with type 2 diabetes

Carolina Restrepo, Sheila Patel, Emilio Werden, Mohamed Salah Khlif, Rebecca Singleton, Laura J Bird, Elif Ekinci, Richard MacIsaac, Piyush Srivastava, Louise Burrell, Amy Brodtmann

Journal article  |  2020  |  Alzheimer's & Dementia

Reduced urinary levels of angiotensin-converting enzyme 2 activity predict acute kidney injury in critically ill patients

Laurent Bitker, Sheila K Patel, Intissar Bittar, Glenn M Eastwood, Rinaldo Bellomo, Louise M Burrell

Journal article  |  2020  |  CRITICAL CARE AND RESUSCITATION

Objective: Angiotensin-converting enzyme 2 activity reflects non-classical renin–angiotensin system upregulation. We assessed the ..

Plasma desmosine, a biomarker of elastin degradation, predicts outcomes in coronary artery disease

Z Iskandar, S Patel, T Lancefield, M Freeman, M Horrigan, O Farouque, JTJ Huang, CC Lang, LM Burrell, AM Choy

Conference Proceedings  |  2020  |  EUROPEAN HEART JOURNAL

Abstract Background Recent evidence from animal studies suggests that elastin ..

Plasma ACE2 activity is persistently elevated following SARS-CoV-2 infection: implications for COVID-19 pathogenesis and consequences

Sheila Patel, Jennifer Juno, Wen Shi Lee, Kathleen Wragg, Mark Hogarth, Stephen Kent, Louise Burrell

Journal article  |  2020

COVID-19 causes persistent endothelial inflammation, lung and cardiovascular complications. SARS-CoV-2 utilises the catalytic site..