Robin McAllen

Advancing respiratory-cardiovascular physiology with the working heart-brainstem preparation over 25 years

Julian FR Paton, Benedito H Machado, Davi JA Moraes, Daniel B Zoccal, Ana P Abdala, Jeffrey C Smith, Vagner R Antunes, David Murphy, Mathias Dutschmann, Rishi R Dhingra, Robin McAllen, Anthony E Pickering, Richard JA Wilson, Trevor A Day, Nicole O Barioni, Andrew M Allen, Clement Menuet, Joseph Donnelly, Igor Felippe, Walter M St-John

Journal article  |  2022  |  JOURNAL OF PHYSIOLOGY-LONDON

Twenty-five years ago, a new physiological preparation called the working heart-brainstem preparation (WHBP) was introduced with t..

Reflex regulation of systemic inflammation by the autonomic nervous system.

Robin M McAllen, Michael J McKinley, Davide Martelli

Journal article  |  2022  |  Auton Neurosci

This short review focusses on the inflammatory reflex, which acts in negative feedback manner to moderate the inflammatory consequ..

The endogenous inflammatory reflex inhibits the inflammatory response to different immune challenges in mice

Alessandra Occhinegro, Chinn Yi Wong, Brendon Y Chua, David C Jackson, Michael J McKinley, Robin M McAllen, Davide Martelli

Journal article  |  2021  |  BRAIN BEHAVIOR AND IMMUNITY

The splanchnic anti-inflammatory pathway, the efferent arm of the endogenous inflammatory reflex, has been shown to suppress the a..

Selective optogenetic stimulation of efferent fi bers in the vagus nerve of a large mammal

Lindsea C Booth, Song T Yao, Alla Korsak, David GS Farmer, Sally G Hood, Daniel McCormick, Quinn Boesley, Angela A Connelly, Stuart J McDougall, Willian S Korim, Sarah-Jane Guild, Svetlana Mastitskaya, Phuong Le, Anja G Teschemacher, Sergey Kasparov, Gareth L Ackland, Simon C Malpas, Robin M McAllen, Andrew M Allen, Clive N May, et al.

Journal article  |  2021  |  BRAIN STIMULATION

BACKGROUND: Electrical stimulation applied to individual organs, peripheral nerves, or specific brain regions has been used to tre..

Sympathetic nerves control bacterial clearance

Yugeesh R Lankadeva, Clive N May, Michael J McKinley, Melanie R Neeland, Shuai Ma, Dianna M Hocking, Roy Robins-Browne, Sammy Bedoui, David GS Farmer, Simon R Bailey, Davide Martelli, Robin M McAllen

Journal article  |  2020  |  SCIENTIFIC REPORTS

A neural reflex mediated by the splanchnic sympathetic nerves regulates systemic inflammation in negative feedback fashion, but it..

A new algorithm for drift compensation in multi-unit recordings of action potentials in peripheral autonomic nerves over time.

Catherine E Davey, Artemio Soto-Breceda, Anthony Shafton, Robin M McAllen, John B Furness, David B Grayden, Martin J Stebbing

Journal article  |  2020  |  Journal of Neuroscience Methods

BACKGROUND: Peripheral autonomic nerves control visceral organs and convey information regarding their functional states and are, ..

Prior Ablation of the Splanchnic Sympathetic Nerves Increases Plasma Inflammatory Cytokine Levels and Suppresses Bacteremia in Response to Systemically Administered E. coli in Sheep

Michael McKinley, Kaylani Almeida, Sammy Bedoui, David Farmer, Dianna Hocking, Yugeesh Lankadeva, Davide Martelli, Clive May, Roy Robins-Browne, Robin McAllen

Conference Proceedings  |  2020  |  FASEB JOURNAL

The splanchnic anti-inflammatory pathway requires the brain stem but not the hypothalamus

A Occhinegro, DGS Farmer, MJ McKinley, RM McAllen, D Martellia

Conference Proceedings  |  2019  |  ACTA PHYSIOLOGICA

The splanchnic anti-inflammatory pathway can be exogenously activated to inhibit inflammation

D Martelli, MJ McKinley, RM McAllen

Conference Proceedings  |  2019  |  ACTA PHYSIOLOGICA

On the presence and functional significance of sympathetic premotor neurons with collateralized spinal axons in the rat

David GS Farmer, Natasha Pracejus, Bowen Dempsey, Anita Turner, Phillip Bokiniec, Julian FR Paton, Anthony E Pickering, Jasmine Burguet, Philippe Andrey, Ann K Goodchild, Robin M McAllen, Simon McMullan

Journal article  |  2019  |  JOURNAL OF PHYSIOLOGY-LONDON

KEY POINTS: Spinally-projecting neurons of the rostral ventrolateral medulla (RVLM) determine sympathetic outflow to different ter..