Christopher Reid

The hyperpolarization-activated cyclic nucleotide-gated 4 channel as a potential anti-seizure drug target

Qays Kharouf, A Marie Phillips, Lauren E Bleakley, Emma Morrisroe, Julia Oyrer, Linghan Jia, Andreas Ludwig, Liang Jin, Joseph A Nicolazzo, Elisabetta Cerbai, M Novella Romanelli, Steven Petrou, Christopher A Reid

Journal article  |  2020  |  British Journal of Pharmacology

BACKGROUND AND PURPOSE: Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are encoded by four genes (HCN1-4) with..

Cardiorenal syndrome: Multi-organ dysfunction involving the heart, kidney and vasculature

Feby Savira, Ruth Magaye, Danny Liew, Christopher Reid, Darren J Kelly, Andrew R Kompa, S Jeson Sangaralingham, John C Burnett, David Kaye, Bing H Wang

Journal article  |  2020  |  British Journal of Pharmacology

Cardiorenal syndrome (CRS) is a multi-organ disease, encompassing heart, kidney and vascular system dysfunction. CRS is a worldwid..

Clinical outcomes following ST-elevation myocardial infarction secondary to stent thrombosis treated by percutaneous coronary intervention

Samer Noaman, Jessica O'Brien, Nick Andrianopoulos, Angela L Brennan, Diem Dinh, Christopher Reid, Anand Sharma, William Chan, David Clark, Dion Stub, Sinjini Biswas, Melanie Freeman, Andrew Ajani, Thomas Yip, Stephen J Duffy, Ernesto Oqueli

Conference Proceedings  |  2020  |  Catheterization and Cardiovascular Interventions

The cost-effectiveness of guideline-driven use of drug-eluting stents: propensity-score matched analysis of a seven-year multicentre experience

Thathya Ariyaratne, Zanfina Ademi, Richard Ofori-Asenso, Molla M Huq, Stephen J Duffy, Bryan P Yan, Andrew E Ajani, David J Clark, Baki Billah, Angela L Brennan, Gishel New, Nick Andrianopoulos, Christopher M Reid

Journal article  |  2020  |  Current Medical Research and Opinion

Background: In routine clinical practice, the implantation of a drug-eluting stent (DES) versus a bare metal stent (BMS) for percu..

Re-examining the effect of door-to-balloon delay on STEMI outcomes in the context of unmeasured confounders: a retrospective cohort study

Chee Yoong Foo, Nick Andrianopoulos, Angela Brennan, Andrew Ajani, Christopher M Reid, Stephen J Duffy, David J Clark, Daniel D Reidpath, Nathorn Chaiyakunapruk

Journal article  |  2019  |  Scientific Reports

Literature studying the door-to-balloon time-outcome relation in coronary intervention is limited by the potential of residual bia..

Patient-reported GP health assessments rather than individual cardiovascular risk burden are associated with the engagement in lifestyle changes: population-based survey in South Australia.

David Alejandro Gonzalez-Chica, Jacqueline Bowden, Caroline Miller, Marie Longo, Mark Nelson, Christopher Reid, Nigel Stocks

Journal article  |  2019  |  BMC Family Practice

BACKGROUND: Little is known about whether a more comprehensive health assessment, performed by a general practitioner (GP) during ..

Overcoming challenges to data quality in the ASPREE clinical trial.

Jessica E Lockery, Taya A Collyer, Christopher M Reid, Michael E Ernst, David Gilbertson, Nino Hay, Brenda Kirpach, John J McNeil, Mark R Nelson, Suzanne G Orchard, Kunnapoj Pruksawongsin, Raj C Shah, Rory Wolfe, Robyn L Woods, undefined ASPREE Investigator Group

Journal article  |  2019  |  Trials

BACKGROUND: Large-scale studies risk generating inaccurate and missing data due to the complexity of data collection. Technology h..

Trends of Use and Outcomes Associated With Glycoprotein-IIb/IIIa Inhibitors in Patients With Acute Coronary Syndromes Undergoing Percutaneous Coronary Intervention

Rochelle M Gellatly, Cia Connell, Christianne Tan, Nick Andrianopoulos, Andrew E Ajani, David J Clark, Shane Nanayakkara, Martin Sebastian, Angela Brennan, Melanie Freeman, Jessica O'Brien, Laura A Selkrig, Christopher M Reid, Stephen J Duffy

Journal article  |  2019  |  Annals of Pharmacotherapy

Association of Body Mass Index and Extreme Obesity With Long-Term Outcomes Following Percutaneous Coronary Intervention

Sinjini Biswas, Nick Andrianopoulos, Diem Dinh, Stephen J Duffy, Jeffrey Lefkovits, Angela Brennan, Samer Noaman, Andrew Ajani, David J Clark, Melanie Freeman, Ernesto Oqueli, Chin Hiew, Christopher M Reid, Dion Stub, William Chan

Journal article  |  2019  |  Journal of the American Heart Association

Background Previous studies have reported a protective effect of obesity compared with normal body mass index (BMI) in patients un..

Change in Blood Pressure Variability Among Treated Elderly Hypertensive Patients and Its Association With Mortality.

Enayet K Chowdhury, Mark R Nelson, Lindon MH Wing, Garry LR Jennings, Lawrence J Beilin, Christopher M Reid, undefined Second Australian National Blood Pressure Study Group †, undefined Second Australian National Blood Pressure Study Group<xref ref-type="author-note" rid="jah34572-note-1001">^†</xref>

Journal article  |  2019  |  Journal of the American Heart Association

Background Information is scarce regarding effects of antihypertensive medication on blood pressure variability (BPV) and associat..

The Early Oscillatory Activity In Human IPSC-Derived Neurons

F Rosa, D Mendez, H Loeffler, G Elsen, S Mueller, N Schwarz, B Uysal, C Reid, S Petrou, H Lerche, S Maljevic

Conference Proceedings  |  2019  |  EPILEPSIA

Risk-Adjusting Key Outcome Measures in a Clinical Quality PCI Registry Development of a Highly Predictive Model Without the Need to Exclude High-Risk Conditions

Mark Tacey, Diem T Dinh, Nick Andrianopoulos, Angela L Brennan, Dion Stub, Danny Liew, Christopher M Reid, Stephen J Duffy, Jeffrey Lefkovits

Journal article  |  2019  |  JACC: Cardiovascular Interventions

Impact of extreme obesity on long-term outcomes following percutaneous coronary intervention

S Biswas, D Dinh, S Noaman, SJ Duffy, J Lefkovits, A Brennan, A Ajani, DJ Clark, M Freeman, E Oqueli, C Hiew, CM Reid, D Stub, W Chan

Conference Proceedings  |  2019  |  EUROPEAN HEART JOURNAL

Impact of cultural and linguistic diversity on ischaemic time and clinical outcomes in patients undergoing percutaneous coronary intervention (PCI) for ST-elevation myocardial infarction (STEMI)

S Biswas, D Dinh, M Lucas, SJ Duffy, A Brennan, D Liew, N Cox, C Neil, CM Reid, J Lefkovits, D Stub

Conference Proceedings  |  2019  |  EUROPEAN HEART JOURNAL

Outcomes in patients with peripheral vascular disease following percutaneous coronary intervention

John Ramzy, Nick Andrianopoulos, Louise Roberts, Stephen J Duffy, David Clark, Andrew W Teh, Andrew E Ajani, Christopher M Reid, Angela Brennan, Melanie Freeman

Journal article  |  2019  |  Catheterization and Cardiovascular Interventions

Impact of Gender and Door-to-Balloon Times on Long-Term Mortality in Patients Presenting With ST-Elevation Myocardial Infarction

Alexandra C Murphy, Matias B Yudi, Omar Farouque, Diem Dinh, Stephen J Duffy, Angela Brennan, Christopher M Reid, Nick Andrianopoulos, Anoop N Koshy, Lorelle Martin, Misha Dagan, Melanie Freeman, David Blusztein, Andrew E Ajani, David J Clark

Journal article  |  2019  |  The American Journal of Cardiology

Using a Multiplex Nucleic Acid in situ Hybridization Technique to Determine HCN4 mRNA Expression in the Adult Rodent Brain

Julia Oyrer, Lauren E Bleakley, Kay L Richards, Snezana Maljevic, A Marie Phillips, Steven Petrou, Cameron J Nowell, Christopher A Reid

Journal article  |  2019  |  Frontiers in Molecular Neuroscience

Relaxin-3 receptor (RXFP3) expression by gaba neurons in hippocampus and amygdala and effects of RXFP3 activation on behaviour

V Rytova, M Nategh, TD Aumann, H Albert-Gasco, CA Reid, RAD Bathgate, FE Oloucha-Bordonau, S Ma, AL Gundlach

Conference Proceedings  |  2019  |  JOURNAL OF NEUROCHEMISTRY

Impact of Pre-Procedural Blood Pressure on Long-Term Outcomes Following Percutaneous Coronary Intervention

Josephine Warren, Shane Nanayakkara, Nick Andrianopoulos, Angela Brennan, Diem Dinh, Matias Yudi, David Clark, Andrew E Ajani, Christopher M Reid, Laura Selkrig, James Shaw, Chin Hiew, Melanie Freeman, David Kaye, Bronwyn A Kingwell, Anthony M Dart, Stephen J Duffy

Journal article  |  2019  |  Journal of the American College of Cardiology

May Measurement Month 2017: an analysis of blood pressure screening results from Australia-South-East Asia and Australasia

Revathy Carnagarin, Ricardo Fonseca, Derrin Brockman, Dagmara Hering, Vance B Matthews, Anastasia Mihailidou, Christopher Reid, Rebecca Lee, Gavin W Lambert, Louise M Burrell, James E Sharman, Xin Xia, Neil R Poulter, Thomas Beaney, Shariful M Islam, Melinda Carrington, Markus P Schlaich

Journal article  |  2019  |  European Heart Journal Supplements, Volume 21, Issue Supplement_D, April 2019,

Spectrum of GABA(A) receptor variants in epilepsy

Snezana Maljevic, Rikke S Moller, Christopher A Reid, Eduardo Perez-Palma, Dennis Lal, Patrick May, Holger Lerche

Journal article  |  2019  |  Current Opinion in Neurology

Effects of blood pressure and lipid lowering on cognition Results from the HOPE-3 study

Jackie Bosch, Martin O'Donnell, Balakumar Swaminathan, Eva Marie Lonn, Mikul Sharma, Gilles Dagenais, Rafael Diaz, Kamlesh Khunti, Basil S Lewis, Alvaro Avezum, Claes Held, Matyas Keltai, Christopher Reid, William D Toff, Antonio Dans, Lawrence A Leiter, Karen Sliwa, Shun Fu Lee, Janice M Pogue, Robert Hart, et al.

Journal article  |  2019  |  Neurology

Discovering the pharmacodynamics of conolidine and cannabidiol using a cultured neuronal network based workflow

GDC Mendis, G Berecki, E Morrisroe, S Pachernegg, M Li, M Varney, PB Osborne, CA Reid, S Halgamuge, S Petrou

Journal article  |  2019  |  Scientific Reports

What matters most to patients following percutaneous coronary interventions? A new patient-reported outcome measure developed using Rasch analysis.

Sze-Ee Soh, Anna L Barker, Darshini R Ayton, Susannah Ahern, Renata Morello, Jeffrey Lefkovits, Angela L Brennan, Susan Evans, John R Zalcberg, Christopher M Reid, John J McNeil

Journal article  |  2019  |  PLOS ONE

INTRODUCTION: Measuring patient reported outcomes can improve the quality and effectiveness of healthcare interventions. The aim o..

Development of a rapid functional assay that predicts GLUT1 disease severity

Sasha M Zaman, Saul A Mullen, Slave Petrovski, Snezana Maljevic, Elena Gazina, A Marie Phillips, Gabriel Davis Jones, Michael S Hildebrand, John Damiano, Stephane Auvin, Holger Lerche, Yvonne G Weber, Samuel F Berkovic, Ingrid E Scheffer, Christopher A Reid, Steven Petrou

Journal article  |  2018  |  Neurology Genetics

The Challenges of Stem Cell Therapy in Myocardial Infarction and Heart Failure and the Potential Strategies to Improve the Outcomes

Bing Hui Wang, Danny Liew, Kevin W Huang, Li Huang, Wenjie Tang, Darren J Kelly, Christopher Reid, Zhongmin Liu

Journal article  |  2018  |  Nano LIFE

Developing a truly patient-derived outcome measure for cardiac procedures

Darshini Ayton, Sze-Ee Soh, Anna Barker, Susannah Ahern, Renata Morello, Jeffrey Lefkovits, Angela Brennan, Sue Evans, John Zalcberg, Christopher Reid, Johannes Stoelwinder, John McNeil

Conference Proceedings  |  2018  |  QUALITY OF LIFE RESEARCH

Selective Na(V)1.1 activation rescues Dravet syndrome mice from seizures and premature death

Kay L Richards, Carol J Milligan, Robert J Richardson, Nikola Jancovski, Morten Grunnet, Laura H Jacobson, Eivind AB Undheim, Mehdi Mobli, Chun Yuen Chow, Volker Herzig, Agota Csoti, Gyorgy Panyi, Christopher A Reid, Glenn F King, Steven Petrou

Journal article  |  2018  |  Proceedings of the National Academy of Sciences

Rare coding variants in genes encoding GABA(A) receptors in genetic generalised epilepsies: an exome-based case-control study

Patrick May, Simon Girard, Merle Harrer, Dheeraj R Bobbili, Julian Schubert, Stefan Wolking, Felicitas Becker, Pamela Lachance-Touchette, Caroline Meloche, Micheline Gravel, Cristina E Niturad, Julia Knaus, Carolien De Kovel, Mohamad Toliat, Anne Polvi, Michele Iacomino, Rosa Guerrero-Lopez, Stephanie Baulac, Carla Marini, Holger Thiele, et al.

Journal article  |  2018  |  The Lancet Neurology

Impact of Discontinuation of Antiplatelet Therapy Prior to Isolated Valve and Combined Coronary Artery Bypass Graft and Valve Procedures on Short and Intermediate Term Outcomes

James Meneguzzi, Matthew Kilpin, Ying Yan Zhu, Atsuo Doi, Christopher Reid, Lavinia Tran, Philip Hayward, Julian Smith

Journal article  |  2018  |  Heart, Lung and Circulation

Neurons Specifically Activated by Fear Learning in Lateral Amygdala Display Increased Synaptic Strength

CW Butler, YM Wilson, J Oyrer, TJ Karle, S Petrou, JM Gunnersen, M Murphy, CA Reid

Journal article  |  2018  |  eneuro

Can mutation-mediated effects occurring early in development cause long-term seizure susceptibility in genetic generalized epilepsies?

Christopher Alan Reid, Ben Rollo, Steven Petrou, Samuel F Berkovic

Journal article  |  2018  |  Epilepsia

Characterization of a Novel Knock-in Mouse Model of KCNT1 Epileptic Encephalopathy

Lisseth Burbano, Melody Li, Nikola Jancovski, Kay Richards, Elena Gazina, Snezana Maljevic, Christopher Reid, Steven Petrou

Conference Proceedings  |  2018  |  NEUROLOGY

Gain-of-function HCN2 variants in genetic epilepsy

Melody Li, Snezana Maljevic, A Marie Phillips, Slave Petrovski, Michael S Hildebrand, Rosemary Burgess, Therese Mount, Federico Zara, Pasquale Striano, Julian Schubert, Holger Thiele, Peter Nuernberg, Michael Wong, Judith L Weisenberg, Liu Lin Thio, Holger Lerche, Ingrid E Scheffer, Samuel F Berkovic, Steven Petrou, Christopher A Reid

Journal article  |  2018  |  Human Mutation

Method of derivation and differentiation of mouse embryonic stem cells generating synchronous neuronal networks

Elena V Gazina, Emma Morrisroe, Gunarathna DC Mendis, Anna E Michalska, Joseph Chen, Christian M Nefzger, Benjamin N Rollo, Christopher A Reid, Martin F Pera, Steven Petrou

Journal article  |  2018  |  Journal of Neuroscience Methods

Ion Channels in Genetic Epilepsy: From Genes and Mechanisms to Disease-Targeted Therapies

Julia Oyrer, Snezana Maljevic, Ingrid E Scheffer, Samuel F Berkovic, Steven Petrou, Christopher A Reid

Journal article  |  2018  |  Pharmacological Reviews

Models for discovery of targeted therapy in genetic epileptic encephalopathies

Snezana Maljevic, Christopher A Reid, Steven Petrou

Journal article  |  2017  |  Journal of Neurochemistry

Functional variants in HCN4 and CACNA1H may contribute to genetic generalized epilepsy.

Felicitas Becker, Christopher A Reid, Kerstin Hallmann, Han-Shen Tae, A Marie Phillips, Georgeta Teodorescu, Yvonne G Weber, Ailing Kleefuss-Lie, Christian Elger, Edward Perez-Reyes, Steven Petrou, Wolfram S Kunz, Holger Lerche, Snezana Maljevic

Journal article  |  2017  |  Epilepsia Open

Objective: Genetic generalized epilepsy (GGE) encompasses seizure disorders characterized by spike-and-wave discharges (SWD) origi..

Gabapentin Modulates HCN4 Channel Voltage-Dependence

Han-Shen Tae, Kelly M Smith, A Marie Phillips, Kieran A Boyle, Melody Li, Ian C Forster, Robert J Hatch, Robert Richardson, David I Hughes, Brett A Graham, Steven Petrou, Christopher A Reid

Journal article  |  2017  |  Frontiers in Pharmacology

KCTD12 modulation of GABA(B) receptor function

Melody Li, Carol J Milligan, Haiyan Wang, Andrew Walker, Leonid Churilov, Andrew J Lawrence, Christopher A Reid, Seth C Hopkins, Steven Petrou

Journal article  |  2017  |  Pharmacology Research & Perspectives

Gap Junctions Link Regular-Spiking and Fast-Spiking Interneurons in Layer 5 Somatosensory Cortex

Robert J Hatch, G Dulini C Mendis, Kai Kaila, Christopher A Reid, Steven Petrou

Journal article  |  2017  |  Frontiers in Cellular Neuroscience

Optogenetic Demonstration of Functional Innervation of Mouse Colon by Neurons Derived From Transplanted Neural Cells

Lincon A Stamp, Rachel M Gwynne, Jaime PP Foong, Alan E Lomax, Marlene M Hao, David I Kaplan, Christopher A Reid, Steven Petrou, Andrew M Allen, Joel C Bornstein, Heather M Young

Journal article  |  2017  |  Gastroenterology

Myoclonus Epilepsy and Ataxia due to KCNC1 Mutation: Analysis of 20 Cases and K plus Channel Properties

Karen L Oliver, Silvana Franceschetti, Carol J Milligan, Mikko Muona, Simone A Mandelstam, Laura Canafoglia, Anna M Boguszewska-Chachulska, Amos D Korczyn, Francesca Bisulli, Carlo Di Bonaventura, Francesca Ragona, Roberto Michelucci, Bruria Ben-Zeev, Rachel Straussberg, Ferruccio Panzica, Joao Massano, Daniel Friedman, Arielle Crespel, Bernt A Engelsen, Frederick Andermann, et al.

Journal article  |  2017  |  Annals of Neurology

Synaptic Zn2 and febrile seizure susceptibility

Christopher A Reid, Michael S Hildebrand, Saul A Mullen, Joanne M Hildebrand, Samuel F Berkovic, Steven Petrou

Journal article  |  2017  |  British Journal of Pharmacology

Interleukin-1 beta has trophic effects in microglia and its release is mediated by P2X7R pore

Mastura Monif, Christopher A Reid, Kim L Powell, Katherine J Drummond, Terrence J O'Brien, David A Williams

Journal article  |  2016  |  Journal of Neuroinflammation

A targeted resequencing gene panel for focal epilepsy

Michael S Hildebrand, Candace T Myers, Gemma L Carvill, Brigid M Regan, John A Damiano, Saul A Mullen, Mark R Newton, Umesh Nair, Elena V Gazina, Carol J Milligan, Christopher A Reid, Steven Petrou, Ingrid E Scheffer, Samuel F Berkovic, Heather C Mefford

Journal article  |  2016  |  Neurology

Use of Local Field Potentials of Dissociated Cultures Grown on Multi-Electrode Arrays for Pharmacological Assays

GDC Mendis, E Morrisroe, CA Reid, SK Halgamuge, S Petrou

Conference Proceedings  |  2016  |  2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)

Loss of synaptic Zn2 transporter function increases risk of febrile seizures

Michael S Hildebrand, A Marie Phillips, Saul A Mullen, Paul A Adlard, Katia Hardies, John A Damiano, Verena Wimmer, Susannah T Bellows, Jacinta M McMahon, Rosemary Burgess, Rik Hendrickx, Sarah Weckhuysen, Arvid Suls, Peter De Jonghe, Ingrid E Scheffer, Steven Petrou, Samuel F Berkovic, Christopher A Reid

Journal article  |  2015  |  Scientific Reports

Generation of Local CA1 gamma Oscillations by Tetanic Stimulation

Robert J Hatch, Christopher A Reid, Steven Petrou

Journal article  |  2015  |  Journal of Visualized Experiments

PRIMA1 mutation: a new cause of nocturnal frontal lobe epilepsy

Michael S Hildebrand, Rick Tankard, Elena V Gazina, John A Damiano, Kate M Lawrence, Hans-Henrik M Dahl, Brigid M Regan, Aiden Eliot Shearer, Richard JH Smith, Carla Marini, Renzo Guerrini, Angelo Labate, Antonio Gambardella, Paolo Tinuper, Laura Lichetta, Sara Baldassari, Francesca Bisulli, Tommaso Pippucci, Ingrid E Scheffer, Christopher A Reid, et al.

Journal article  |  2015  |  Annals of Clinical and Translational Neurology

Generalised seizure--mediated changes in HCN channels associates with learning deficits

C Reid

Conference Proceedings  |  2015  |  JOURNAL OF NEUROCHEMISTRY

'Neonatal' Na(v)1.2 reduces neuronal excitability and affects seizure susceptibility and behaviour

Elena V Gazina, Bryan TW Leaw, Kay L Richards, Verena C Wimmer, Tae H Kim, Timothy D Aumann, Travis J Featherby, Leonid Churilov, Vicki E Hammond, Christopher A Reid, Steven Petrou

Journal article  |  2015  |  Human Molecular Genetics

Reduction of p75 neurotrophin receptor ameliorates the cognitive deficits in a model of Alzheimer's disease

Mark Murphy, Yvette M Wilson, Ernesto Vargas, Kathryn M Munro, Belinda Smith, Amy Huang, Qiao-Xin Li, Junhua Xiao, Colin L Masters, Christopher A Reid, Graham L Barrett

Journal article  |  2015  |  Neurobiology of Aging

Oxcarbazepine and its active metabolite, (S)-licarbazepine, exacerbate seizures in a mouse model of genetic generalized epilepsy

Tae Hwan Kim, Christopher A Reid, Steven Petrou

Journal article  |  2015  |  Epilepsia

Mapping somatosensory connectivity in adult mice using diffusion MRI tractography and super-resolution track density imaging

Kay Richards, Fernando Calamante, Jacques-Donald Tournier, Nyoman D Kurniawan, Farnoosh Sadeghian, Alexander R Retchford, Gabriel Davis Jones, Christopher A Reid, David C Reutens, Roger Ordidge, Alan Connelly, Steven Petrou

Journal article  |  2014  |  NeuroImage

Epilepsy, energy deficiency and new therapeutic approaches including diet

Christopher A Reid, Saul Mullen, Tae Hwan Kim, Steven Petrou

Journal article  |  2014  |  Pharmacology & Therapeutics

P2X7 receptors are a potential novel target for anti-glioma therapies

Mastura Monif, Terence J O'Brien, Kate J Drummond, Christopher A Reid, Simon V Liubinas, David A Williams

Journal article  |  2014  |  Journal of Inflammation

Reduced dendritic arborization and hyperexcitability of pyramidal neurons in a Scn1b-based model of Dravet syndrome

Christopher A Reid, Bryan Leaw, Kay L Richards, Robert Richardson, Verena Wimmer, Christiaan Yu, Elisa L Hill-Yardin, Holger Lerche, Ingrid E Scheffer, Samuel F Berkovic, Steven Petrou

Journal article  |  2014  |  Brain

HCN channelopathy and cardiac electrophysiologic dysfunction in genetic and acquired rat epilepsy models

Kim L Powell, Nigel C Jones, Jeremy T Kennard, Caroline Ng, Vijay Urmaliya, Shannen Lau, Adora Tran, Thomas Zheng, Ezgi Ozturk, Gabi Dezsi, Ika Megatia, Lea M Delbridge, Didier Pinault, Christopher A Reid, Paul J White, Terence J O'Brien

Journal article  |  2014  |  Epilepsia

Enhanced in vitro CA1 network activity in a sodium channel beta 1(C121W) subunit model of genetic epilepsy

Robert J Hatch, Christopher A Reid, Steven Petrou

Journal article  |  2014  |  Epilepsia

Spike-and-wave discharge mediated reduction in hippocampal HCN1 channel function associates with learning deficits in a genetic mouse model of epilepsy

A Marie Phillips, Taehwan Kim, Ernesto Vargas, Steven Petrou, Christopher A Reid

Journal article  |  2014  |  Neurobiology of Disease

Acute effect of carbamazepine on corticothalamic 5-9-Hz and thalamocortical spindle (10-16-Hz) oscillations in the rat

Thomas W Zheng, Terence J O'Brien, Sofya P Kulikova, Christopher A Reid, Margaret J Morris, Didier Pinault

Journal article  |  2014  |  European Journal of Neuroscience

Low glycaemic index diet reduces seizure susceptibility in a syndrome-specific mouse model of generalized epilepsy

Tae Hwan Kim, Steven Petrou, Christopher A Reid

Journal article  |  2014  |  Epilepsy Research

The auxiliary GABA(B) receptor subunits KCTD12 and KCTD16 differentially modulate receptor function

Melody YS Li, Carol Milligan, Haiyan Wang, Christopher Reid, Seth Hopkins, Steven Petrou

Conference Proceedings  |  2013  |  ACTA PHARMACOLOGICA SINICA

The auxiliary GABA(B) receptor subunits KCTD12 and KCTD16 differentially modulate receptor function

Melody YS Li, Carol Milligan, Haiyan Wang, Christopher Reid, Seth Hopkins, Steven Petrou

Conference Proceedings  |  2013  |  ACTA PHARMACOLOGICA SINICA

SPIKE-AND-WAVE DISCHARGE MEDIATED REDUCTION IN HIPPOCAMPAL HCN1 CHANNEL FUNCTION ASSOCIATES WITH LEARNING DEFICITS IN A GENETIC MOUSE MODEL OF EPILEPSY

AM Phillips, TH Kim, E Vargas, S Petrou, CA Reid

Conference Proceedings  |  2013  |  EPILEPSIA

Perturbations in cortical development and neuronal network excitability arising from prenatal exposure to benzodiazepines in mice

Matilda Haas, Zhengdong Qu, Tae Hwan Kim, Ernesto Vargas, Kenneth Campbell, Steven Petrou, Seong-Seng Tan, Christopher A Reid, Julian Heng

Journal article  |  2013  |  European Journal of Neuroscience

Hippocampal volume and cell density changes in a mouse model of human genetic epilepsy

Kay L Richards, Nyoman D Kurniawan, Zhengyi Yang, Tae Hwan Kim, Marianne D Keller, Jun Low, Jeremy FP Ullmann, Stacey Cole, Samuel Foong, Graham J Galloway, Christopher A Reid, George Paxinos, David C Reutens, Steven Petrou

Journal article  |  2013  |  Neurology

Multiple molecular mechanisms for a single GABA(A) mutation in epilepsy

Christopher A Reid, Taehwan Kim, A Marie Phillips, Jun Low, Samuel F Berkovic, Bernhard Luscher, Steven Petrou

Journal article  |  2013  |  Neurology

Two lines of transgenic mice expressing cre-recombinase exhibit increased seizure susceptibility

Tae Hwan Kim, Kay Richards, Julian Heng, Steven Petrou, Christopher A Reid

Journal article  |  2013  |  Epilepsy Research

Triheptanoin reduces seizure susceptibility in a syndrome-specific mouse model of generalized epilepsy

Tae Hwan Kim, Karin Borges, Steven Petrou, Christopher A Reid

Journal article  |  2013  |  Epilepsy Research

Genetic and pharmacological modulation of giant depolarizing potentials in the neonatal hippocampus associates with increased seizure susceptibility

Ernesto Vargas, Steven Petrou, Christopher A Reid

Journal article  |  2013  |  Journal of Physiology

Multiple molecular mechanisms for a single GABAA mutation in epilepsy

CA Reid, T Kim, AM Phillips, J LOW, SF Berkovic, B Luscher, S Petrou

Journal article  |  2013  |  Neurology

Rhythmic neuronal activity in S2 somatosensory and insular cortices contribute to the initiation of absence-related spike-and-wave discharges

Thomas W Zheng, Terence J O'Brien, Margaret J Morris, Christopher A Reid, Valentina Jovanovska, Patrick O'Brien, Leena van Raay, Arun K Gandrathi, Didier Pinault

Journal article  |  2012  |  Epilepsia

Early Development of Electrical Excitability in the Mouse Enteric Nervous System

Marlene M Hao, Alan E Lomax, Sonja J McKeown, Christopher A Reid, Heather M Young, Joel C Bornstein

Journal article  |  2012  |  Journal of Neuroscience

Glutamate is associated with a higher risk of seizures in patients with gliomas

Tanya I Yuen, Andrew P Morokoff, Andrew Bjorksten, Giovanna D'Abaco, Lucy Paradiso, Sue Finch, Daniel Wong, Christopher A Reid, Kim L Powell, Kate J Drummond, Mark A Rosenthal, Andrew H Kaye, Terence J O'Brien

Journal article  |  2012  |  Neurology

Neurons derived from human embryonic stem cells extend long-distance axonal projections through growth along host white matter tracts after intra-cerebral transplantation

Mark Denham, Clare L Parish, Bryan Leaw, Jordan Wright, Christopher A Reid, Steven Petrou, Mirella Dottori, Lachlan H Thompson

Journal article  |  2012  |  Frontiers in Cellular Neuroscience

Channelrhodopsins shed light on a new pathway in absence epilepsy

S Petrou, CA Reid

Journal article  |  2012  |  Future Neurology

The GABAAγ2(R43Q) mouse model of human genetic epilepsy

S Petrou, CA Reid

Reference Work  |  2012

HCN channelopathies: pathophysiology in genetic epilepsy and therapeutic implications

Christopher A Reid, A Marie Phillips, Steven Petrou

Journal article  |  2012  |  British Journal of Pharmacology

RESCUE OF SPATIAL MEMORY IN ALZHEIMER'S DISEASE MICE BY KNOCKDOWN OF THE P75 NEUROTROPHIN RECEPTOR

G Barrett, M Murphy, Q-X Li, C Reid, Y Wilson

Conference Proceedings  |  2011  |  EUROPEAN JOURNAL OF NEUROLOGY

GABA(A) receptor mutations in epilepsy

Christopher A Reid, Dimitri M Kullmann

Journal article  |  2011  |  European Journal of Neuroscience

Stargazin and AMPA receptor membrane expression is increased in the somatosensory cortex of Genetic Absence Epilepsy Rats from Strasbourg

JTT Kennard, R Barmanray, S Sampurno, E Ozturk, CA Reid, L Paradiso, GM D'Abaco, AH Kaye, SJ Foote, TJ O'Brien, KL Powell

Journal article  |  2011  |  Neurobiology of Disease

Low blood glucose precipitates spike-and-wave activity in genetically predisposed animals

Christopher A Reid, Tae Hwan Kim, Samuel F Berkovic, Steven Petrou

Journal article  |  2011  |  Epilepsia

Temperature elevation increases GABA(A)-mediated cortical inhibition in a mouse model of genetic epilepsy

Elisa L Hill, Suzanne Hosie, Rachel S Mulligan, Kay L Richards, Philip J Davies, Celine M Dube, Tallie Z Baram, Christopher A Reid, Mathew V Jones, Steven Petrou

Journal article  |  2011  |  Epilepsia

Seizure-like thalamocortical rhythms initiate in the deep layers of the cortex in a co-culture model

Brendan EL Adams, Mervyn Kyi, Christopher A Reid, Damian E Myers, Shenghong Xu, David A Williams, Terence J O'Brien

Journal article  |  2011  |  Experimental Neurology

New therapeutic opportunities in epilepsy: A genetic perspective

Christopher A Reid, Graeme D Jackson, Samuel F Berkovic, Steven Petrou

Journal article  |  2010  |  Pharmacology and Therapeutics

Axon initial segment dysfunction in a mouse model of genetic epilepsy with febrile seizures plus

Verena C Wimmer, Christopher A Reid, Suzanne Mitchell, Kay L Richards, Byron B Scaf, Bryan T Leaw, Elisa L Hill, Michel Royeck, Marie-Therese Horstmann, Brett A Cromer, Philip J Davies, Ruwei Xu, Holger Lerche, Samuel F Berkovic, Heinz Beck, Steven Petrou

Journal article  |  2010  |  Journal of Clinical Investigation

Axon initial segment dysfunction in epilepsy

Verena C Wimmer, Christopher A Reid, Eva Y-W So, Samuel F Berkovic, Steven Petrou

Journal article  |  2010  |  The Journal of Physiology

Augmented Currents of an HCN2 Variant in Patients with Febrile Seizure Syndromes

Leanne M Dibbens, Christopher A Reid, Bree Hodgson, Evan A Thomas, Alison M Phillips, Elena Gazina, Brett A Cromer, Alison L Clarke, Tallie Z Baram, Ingrid E Scheffer, Samuel F Berkovic, Steven Petrou

Journal article  |  2010  |  Annals of Neurology

DIFFERENTIAL EXPRESSION OF EXON 5 SPLICE VARIANTS OF SODIUM CHANNEL alpha SUBUNIT mRNAs IN THE DEVELOPING MOUSE BRAIN

EV Gazina, KL Richards, MBC Mokhtar, EA Thomas, CA Reid, S Petrou

Journal article  |  2010  |  Neuroscience

Cocaine-mediated synaptic potentiation is absent in VTA neurons from mGlu5-deficient mice

Michael K Bird, Christopher A Reid, Feng Chen, Heneu O Tan, Steven Petrou, Andrew J Lawrence

Journal article  |  2010  |  International Journal of Neuropsychopharmacology

Mossy fiber sprouting interacts with sodium channel mutations to increase dentate gyrus excitability

Evan A Thomas, Christopher A Reid, Steven Petrou

Journal article  |  2010  |  Epilepsia

Enhanced Spatial Memory and Hippocampal Long-Term Potentiation in p75 Neurotrophin Receptor Knockout Mice

Graham L Barrett, Christopher A Reid, Christina Tsafoulis, Wenmei Zhu, David A Williams, Antonio G Paolini, Jennifer Trieu, Mark Murphy

Journal article  |  2010  |  Hippocampus

BENZODIAZEPINE EFFICACY IN A MOUSE MODEL OF ABSENCE EPILEPSY BASED ON A HUMAN MUTATION IN THE GAMMA2 GABA-A SUBUNIT

Christopher A Reid, N Taylor, SF Berkovic, S Petrou

Conference Proceedings  |  2009  |  EPILEPSIA

THE GAERS CA(V)3.2 T-TYPE CALCIUM CHANNEL MUTATION (GCM) AFFECTS RELATIVE EXPRESSION OF THE CHANNEL SPLICE VARIANTS

Caroline Ng, JR Tyson, KL Powell, SM Cain, CA Reid, TP Snutch, TJ O'Brien

Conference Proceedings  |  2009  |  EPILEPSIA

ALTERED GLUTAMATE TRANSPORER EXPRESSION AND INCREASED GLUTAMATE LEVELS IN TUMORS ARE SPECIFICALLY ASSOCIATED WITH TUMOR ASSOCIATED SEIZURES

T O'Brien, T Yuen, A Morokoff, A Bjorksten, G D'Abaco, K Powell, C Reid, K Drummond, M Rosenthal, L Paradiso, A Kaye

Conference Proceedings  |  2009  |  EPILEPSIA

Prediction by Modeling That Epilepsy May Be Caused by Very Small Functional Changes in Ion Channels

Evan A Thomas, Christopher A Reid, Samuel F Berhovic, Steven Petrou

Journal article  |  2009  |  Archives of Neurology

Excitotoxic-mediated transcriptional decreases in HCN2 channel function increase network excitability in CA1

Brendan EL Adams, Christopher A Reid, Damian Myers, Caroline Ng, Kim Powell, A Marie Phillips, Thomas Zheng, Terence J O'Brien, David A Williams

Journal article  |  2009  |  Experimental Neurology

The P2X(7) Receptor Drives Microglial Activation and Proliferation: A Trophic Role for P2X(7)R Pore

Mastura Monif, Christopher A Reid, Kim L Powell, Megan L Smart, David A Williams

Journal article  |  2009  |  Journal of Neuroscience

A Ca(v)3.2 T-Type Calcium Channel Point Mutation Has Splice-Variant-Specific Effects on Function and Segregates with Seizure Expression in a Polygenic Rat Model of Absence Epilepsy

Kim L Powell, Stuart M Cain, Caroline Ng, Shreerang Sirdesai, Laurence S David, Mervyn Kyi, Esperanza Garcia, John R Tyson, Christopher A Reid, Melanie Bahlo, Simon J Foote, Terrance P Snutch, Terence J O'Brien

Journal article  |  2009  |  Journal of Neuroscience

Mechanisms of human inherited epilepsies

Christopher A Reid, Samuel F Berkovic, Steven Petrou

Journal article  |  2009  |  Progress in Neurobiology

Oxcarbazepine, not its active metabolite, potentiates GABA(A) activation and aggravates absence seizures

Thomas Zheng, Alison L Clarke, Margaret J Morris, Christopher A Reid, Steven Petrou, Terence J O'Brien

Journal article  |  2009  |  Epilepsia

Developmental impact of a familial GABA(A) receptor epilepsy mutation

Cindy Chiu, Christopher A Reid, Heneu O Tan, Philip J Davies, Frank N Single, Irene Koukoulas, Samuel F Berkovic, Seong-Seng Tan, Rolf Sprengel, Mathew V Jones, Steven Petrou

Journal article  |  2008  |  Annals of Neurology

Genetic absence epilepsy rats from Strasbourg have increased corticothalamic expression of stargazin

KL Powell, M Kyi, CA Reid, L Paradiso, GM D'Abaco, AH Kaye, SJ Foote, TJ O'Brien

Journal article  |  2008  |  Neurobiology of Disease

Sub region-specific modulation of synchronous neuronal burst firing after a kainic acid insult in organotypic hippocampal cultures

Christopher A Reid, Brendan EL Adams, Damian Myers, Terence J O'Brien, David A Williams

Journal article  |  2008  |  BMC Neuroscience

Increased thalamic inhibition in the absence seizure prone DBA/2J mouse

Heneu O Tan, Christopher A Reid, Cindy Chiu, Mathew V Jones, Steven Petrou

Journal article  |  2008  |  Epilepsia

A CAV3.2 T-TYPE CALCIUM CHANNEL POINT MUTATION HAS SPLICE VARIANT-SPECIFIC EFFECTS ON FUNCTION AND SEGREGATES WITH SEIZURE EXPRESSION IN A POLYGENIC RAT MODEL OF ABSENCE EPILEPSY

Caroline Ng, Kim L Powell, SM Cain, S Sirdesai, LS David, M Kyi, E Garcia, J Tyson, Christopher A Reid, M Bahlo, SJ Foote, TP Snutch, TJ O'Brien

Conference Proceedings  |  2008  |  EPILEPSIA

DO HOMOZYGOUS BETA1 (C121W) MUTANT MICE MODEL DRAVET SYNDROME?

Christopher A Reid, Elisa L Hill, P Davies, Samuel F Berkovic, S Petrou

Conference Proceedings  |  2008  |  EPILEPSIA

Spontaneous release from mossy fiber terminals inhibits Ni2 -sensitive T-type Ca2 channels of CA3 pyramidal neurons in the rat organotypic hippocampal slice

Christopher A Reid, Shenghong Xu, David A Williams

Journal article  |  2008  |  Hippocampus

A novel mutation in the rat Ca(v)3.2 T-type Ca2 channel CACNA1H gene increases absence seizure expression

Kim L Powell, S Sirdesai, M Kyi, C Ng, E Garcia, CA Reid, D Pinault, SJ Foote, TP Snutch, TJ O'Brien

Conference Proceedings  |  2007  |  EPILEPSIA

Early developmental expression of a familial GABAA epilepsy gene increases adult seizure susceptibility

Christopher A Reid, C Chiu, HO Tan, P Davies, S Tan, M Jones, S Petrou

Conference Proceedings  |  2007  |  EPILEPSIA

Oxcarbazepine but not its active metabolite, MHD, aggravates genetic absences seizures in the rat and potentiates GABA(A) receptor activation

Thomas W Zheng, AL Clarke, MJ Morris, CA Reid, S Petrou, TJ O'Brien

Conference Proceedings  |  2007  |  EPILEPSIA

High speed Ca2 -fluorescence imaging reveals hippocampal regional impacts of excitotoxic insult on synchronized burst firing

Brendan E Adams, DE Myers, CA Reid, TJ O'Brien, DA Williams

Conference Proceedings  |  2007  |  EPILEPSIA

Reduced cortical inhibition in a mouse model of familial childhood absence epilepsy

Heneu O Tan, Christopher A Reid, Frank N Single, Philip J Davies, Cindy Chiu, Susan Murphy, Alison L Clarke, Leanne Dibbens, Heinz Krestel, John C Mulley, undefined others

Journal article  |  2007  |  Proceedings of the National Academy of Sciences of the United States of America

The mechanism of carbamazepine aggravation of absence seizures

Lige Liu, Thomas Zheng, Margaret J Morris, Charlott Wallengren, Alison L Clarke, Christopher A Reid, Steven Petrou, Terence J O'Brien

Journal article  |  2006  |  Journal of Pharmacology and Experimental Therapeutics

Null mutation of the alpha 4 nicotinic receptor subunit increases the propensity of muscarinic-mediated neuronal bursting in mouse hippocampal slices

Christopher A Reid, Harold A Coleman, David I Finkelstein, Malcolm K Horne, John Drago

Journal article  |  2006  |  Neuropharmacology

Changes in HCN expression in the hippocampus are not critical to limbic epileptogenesis: Contrasting results in two animal models

Kim L Powell, Caroline Ng, Sheng-Hong Xu, Terence J O'Brien, David A Williams, Chris A Reid

Conference Proceedings  |  2006  |  EPILEPSIA

Reciprocal burst activity in thalamocortical co-cultures from postnatal rats

M Kyi, S Xu, B Adams, DE Myers, DA Williams, TJ O'Brien, CA Reid

Conference Proceedings  |  2005  |  JOURNAL OF THE NEUROLOGICAL SCIENCES

Development of low-affinity, membrane-targeted Ca2 sensors suitable for measuring presynaptic Ca2

M Monif, ML Smart, CA Reid, DA Williams

Journal article  |  2004  |  Clinical and Experimental Pharmacology and Physiology

Optical quantal analysis indicates that long-term potentiation at single hippocampal mossy fiber synapses is expressed through increased release probability, recruitment of new release sites, and activation of silent synapses

CA Reid, DB Dixon, M Takahashi, TVP Bliss, A Fine

Journal article  |  2004  |  Journal of Neuroscience

Specific fast oscillatory thalamocortical activity in brain slices in the gaers absence epilepsy model

DE Myers, TJ O'Brien, CA Reid, BE Adams, RJ Lohman, S Berkovic, DA Williams

Conference Proceedings  |  2004  |  EPILEPSIA

Presynaptic Ca2 channels: a functional patchwork

CA Reid, JM Bekkers, JD Clernents

Journal article  |  2003  |  Trends in Neurosciences

Optical quantal analysis reveals a presynaptic component of LTP at hippocampal Schaffer-associational synapses

NJ Emptage, CA Reid, A Fine, TVP Bliss

Journal article  |  2003  |  Neuron

Calcium signalling and synaptic plasticity at single hippocampal synapses

A Fine, NJ Emptage, CA Reid, D Dixon, R Fabian-Fine, TVP Bliss

Conference Proceedings  |  2002  |  JOURNAL OF PHYSIOLOGY-LONDON

The role of dendritic spines: comparing the complex with the simple

CA Reid

Journal article  |  2002  |  European Journal of Pharmacology

Postsynaptic calcium transients evoked by activation of individual hippocampal mossy fiber synapses

CA Reid, R Fabian-Fine, A Fine

Journal article  |  2001  |  The Journal of Neuroscience

Calcium stores in hippocampal synaptic boutons mediate short-term plasticity, store-operated Ca2 entry, and spontaneous transmitter release

NJ Emptage, CA Reid, A Fine

Journal article  |  2001  |  Neuron

Learning about kainate receptors

CA Reid, TVP Bliss

Journal article  |  2000  |  Trends in Pharmacological Sciences

Postsynaptic calcium signals at mossy fibre synapses in the hippocampus

CA Reid, TVP Bliss, A Fine

Conference Proceedings  |  2000  |  EUROPEAN JOURNAL OF NEUROSCIENCE

Postsynaptic expression of long-term potentiation in the rat dentate gyrus demonstrated by variance-mean analysis

CA Reid, JD Clements

Journal article  |  1999  |  The Journal of Physiology

N- and P/Q-type Ca2 channels mediate transmitter release with a similar cooperativity at rat hippocampal autapses

CA Reid, JM Bekkers, JD Clements

Journal article  |  1998  |  The Journal of Neuroscience

Nonuniform distribution of Ca2 channel subtypes on presynaptic terminals of excitatory synapses in hippocampal cultures

CA Reid, JA Clements, JM Bekkers

Journal article  |  1997  |  The Journal of Neuroscience

Development of spontaneous seizures over extended electrical kindling. II. Persistence of dentate inhibitory suppression.

NW Milgram, M Michael, S Cammisuli, E Head, J Ferbinteanu, C Reid, MP Murphy, R Racine

Journal article  |  1995  |  Brain Research

The effect of an extended program of perforant path or amygdala kindling on paired-pulse suppression in the dentate gyrus was stud..

Effects of L-deprenyl on manifestations of aging in the rat and dog.

GO Ivy, JT Rick, MP Murphy, E Head, C Reid, NW Milgram

Journal article  |  1994  |  Annals of the New York Academy of Sciences