Vickie Wong

Increased episcleral venous pressure in a mouse model of circumlimbal suture induced ocular hypertension

Vickie HY Wong, Da Zhao, Bang Bui, Cameron J Millar, Christine TO Nguyen

Journal article  |  2021  |  Experimental Eye Research

PURPOSE: To investigate changes in aqueous humor dynamics during intraocular pressure (IOP) elevation induced by circumlimbal sutu..

Gene Therapy Intervention in Neovascular Eye Disease: A Recent Update

Fan-Li Lin, Peng-Yuan Wang, Yu-Fan Chuang, Jiang-Hui Wang, Vickie HY Wong, Bang Bui, Guei-Sheung Liu

Journal article  |  2020  |  Molecular Therapy

Aberrant growth of blood vessels (neovascularization) is a key feature of severe eye diseases that can cause legal blindness, incl..

A drug-tunable Flt23k gene therapy for controlled intervention in retinal neovascularization

Jinying Chen, Fan-Li Lin, Jacqueline YK Leung, Leilei Tu, Jiang-Hui Wang, Yu-Fan Chuang, Fan Li, Hsin-Hui Shen, Gregory J Dusting, Vickie HY Wong, Leszek Lisowski, Alex W Hewitt, Bang V Bui, Jingxiang Zhong, Guei-Sheung Liu

Journal article  |  2020  |  Angiogenesis

Gene therapies that chronically suppress vascular endothelial growth factor (VEGF) represent a new approach for managing retinal v..

Blocking endothelial apoptosis revascularizes the retina in a model of ischemic retinopathy

Zoe L Grant, Lachlan Whitehead, Vickie HY Wong, Zheng He, Richard Y Yan, Abigail R Miles, Andrew Benest, David O Bates, Claudia Prahst, Katie Bentley, Bang Bui, Robert CA Symons, Leigh Coultas

Journal article  |  2020  |  Journal of Clinical Investigation

Aberrant, neovascular retinal blood vessel growth is a vision-threatening complication in ischemic retinal diseases. It is driven ..

Fractalkine-induced microglial vasoregulation occurs within the retina and is altered early in diabetic retinopathy

Samuel Mills, Andrew Jobling, Michael Dixon, Bang Bui, Kirstan Vessey, Joanna Phipps, Ursula Greferath, Gene Venables, Vickie HY Wong, Connie HY Wong, Zheng He, Flora Hui, James Young, Josh Tonc, Elena Ivanova, Botir Sagdullaev, Erica Fletcher

Journal article  |  2020

Local blood flow control within the CNS is critical to proper function and is dependent on coordination between neurons, glia and ..

Response of the Trilaminar Retinal Vessel Network to Intraocular Pressure Elevation in Rat Eyes

Da Zhao, Zheng He, Lin Wang, Brad Fortune, Jeremiah KH Lim, Vickie HY Wong, Christine TO Nguyen, Bang Bui

Journal article  |  2020  |  Investigative Ophthalmology and Visual Science

Purpose: The purpose of this study was to test the hypothesis that the superficial, intermediate, and deep retinal vascular plexus..

Utility of Self-Destructing CRISPR/Cas Constructs for Targeted Gene Editing in the Retina

Fan Li, Sandy SC Hung, Mohd Khairul Nizam Mohd Khalid, Jiang-Hui Wang, Vicki Chrysostomou, Vickie HY Wong, Vikrant Singh, Kristof Wing, Leilei Tu, James A Bender, Alice Pebay, Anna E King, Anthony L Cook, Raymond CB Wong, Bang Bui, Alex W Hewitt, Guei-Sheung Liu

Journal article  |  2019  |  Human Gene Therapy

Reversibility of Retinal Ganglion Cell Dysfunction From Chronic IOP Elevation

Da Zhao, Vickie HY Wong, Christine TO Nguyen, Andrew I Jobling, Erica L Fletcher, Algis J Vingrys, Bang V Bui

Journal article  |  2019  |  Investigative ophthalmology & visual science

Progressive impairments in executive function in the APP/PS1 model of Alzheimer’s disease as measured by translatable touchscreen testing

A Shepherd, JKH Lim, VHY Wong, AM Zeleznikow-Johnston, L Churilov, CTO Nguyen, BV Bui, AJ Hannan, EL Burrows

Journal article  |  2019

Abstract Executive function deficits in Alzheimer’s disease (AD) occur early in disease progression and may be predictive of cogni..

Effect of intraocular pressure on vascular autoregulation of the mouse trilaminar network

Jeremiah Kah Heng Lim, Ronald Hao Wu, Vickie Hoi Ying Wong, Algis J Vingrys, Christine Tram Oanh Nguyen, Bang V Bui

Conference Proceedings  |  2019  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE