Vickie Wong

Retinal Dysfunction in a Mouse Model of HCN1 Genetic Epilepsy.

Da Zhao, Paulo Pinares-Garcia, Chaseley E McKenzie, Lauren E Bleakley, Ian C Forster, Vickie HY Wong, Christine TO Nguyen, Ingrid E Scheffer, Christopher A Reid, Bang V Bui

Journal article  |  2023  |  J Neurosci

Pathogenic variants in HCN1 are associated with a range of epilepsy syndromes including a developmental and epileptic encephalopat..

The Effect of Aging on Retinal Function and Retinal Ganglion Cell Morphology Following Intraocular Pressure Elevation

Pei Ying Lee, Da Zhao, Vickie HY Wong, Vicki Chrysostomou, Jonathan G Crowston, Bang V Bui

Journal article  |  2022  |  FRONTIERS IN AGING NEUROSCIENCE

Aging and elevated intraocular pressure (IOP) are two major risk factors for glaucomatous optic neuropathy; a condition characteri..

Characterization of retinal function and structure in the MPTP murine model of Parkinson's disease

Katie KN Tran, Vickie HY Wong, Jeremiah KH Lim, Ali Shahandeh, Hoang Anh, David Finkelstein, Bang Bui, Christine TO Nguyen

Journal article  |  2022  |  SCIENTIFIC REPORTS

In addition to well characterized motor symptoms, visual disturbances are increasingly recognized as an early manifestation in Par..

Effect of hydroxychloroquine or chloroquine and short wavelength light on in vivo retinal function and structure in mouse eyes

Wilson Heriot, Vickie HY Wong, Zheng He, Hoang Anh, Jeremiah KH Lim, Tomoharu Nishimura, Da Zhao, Andrew B Metha, Bang Bui

Journal article  |  2022  |  CLINICAL AND EXPERIMENTAL OPTOMETRY

CLINICAL RELEVANCE: The use of chloroquine or hydroxychloroquine can lead to both acute and chronic changes to both retinal struct..

White matter tract conductivity is resistant to wide variations in paranodal structure and myelin thickness accompanying the loss of Tyro3: an experimental and simulated analysis

Farrah Blades, Jordan D Chambers, Timothy D Aumann, Christine TO Nguyen, Vickie HY Wong, Andrea Aprico, Eze C Nwoke, Bang Bui, David B Grayden, Trevor J Kilpatrick, Michele D Binder

Journal article  |  2022  |  BRAIN STRUCTURE & FUNCTION

Myelination within the central nervous system (CNS) is crucial for the conduction of action potentials by neurons. Variation in co..

Fractalkine-induced microglial vasoregulation occurs within the retina and is altered early in diabetic retinopathy

Samuel A Mills, Andrew Jobling, Michael A Dixon, Bang Bui, Kirstan A Vessey, Joanna A Phipps, Ursula Greferath, Gene Venables, Vickie HY Wong, Connie HY Wong, Zheng He, Flora Hui, James C Young, Josh Tonc, Elena Ivanova, Botir T Sagdullaev, Erica L Fletcher

Journal article  |  2021  |  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Local blood flow control within the central nervous system (CNS) is critical to proper function and is dependent on coordination b..

Progressive impairments in executive function in the APP/PS1 model of Alzheimer's disease as measured by translatable touchscreen testing

Amy Shepherd, Jeremiah KH Lim, Vicky HY Wong, Ariel M Zeleznikow-Johnston, Leonid Churilov, Christine TO Nguyen, Bang V. Bui, Anthony J Hannan, Emma L Burrows

Journal article  |  2021  |  NEUROBIOLOGY OF AGING

Executive function deficits in Alzheimer's disease (AD) occur early in disease progression and may be predictive of cognitive decl..

Targeted delivery of LM22A-4 by cubosomes protects retinal ganglion cells in an experimental glaucoma model

Yue Ding, Seong H Chow, Jinying Chen, Anton P Le Brun, Chun-Ming Wu, Anthony P Duff, Yajun Wang, Jiangning Song, Jiang-Hui Wang, Vickie HY Wong, Da Zhao, Tomoharu Nishimura, Tzong-Hsien Lee, Charlotte E Conn, Hsien-Yi Hsu, Bang Bui, Guei-Sheung Liu, Hsin-Hui Shen

Journal article  |  2021  |  ACTA BIOMATERIALIA

Glaucoma, a major cause of irreversible blindness worldwide, is associated with elevated intraocular pressure (IOP) and progressiv..

Retinal ganglion cell dysfunction in mice following acute intraocular pressure is exacerbated by P2X7 receptor knockout

Anna YM Wang, Vickie HY Wong, Pei Ying Lee, Bang V Bui, Stefanie Dudczig, Kirstan A Vessey, Erica L Fletcher

Journal article  |  2021  |  SCIENTIFIC REPORTS

There is increasing evidence for the vulnerability of specific retinal ganglion cell (RGC) types in those with glaucoma and in ani..

Increased episcleral venous pressure in a mouse model of circumlimbal suture induced ocular hypertension

Vickie HY Wong, Da Zhao, Bang Bui, Cameron J Millar, Christine TO Nguyen

Journal article  |  2021  |  EXPERIMENTAL EYE RESEARCH

PURPOSE: To investigate changes in aqueous humor dynamics during intraocular pressure (IOP) elevation induced by circumlimbal sutu..