Vickie Wong

Utility of Self-Destructing CRISPR/Cas Constructs for Targeted Gene Editing in the Retina

Fan Li, Sandy SC Hung, Mohd Khairul Nizam Mohd Khalid, Jiang-Hui Wang, Vicki Chrysostomou, Vickie HY Wong, Vikrant Singh, Kristof Wing, Leilei Tu, James A Bender, Alice Pebay, Anna E King, Anthony L Cook, Raymond CB Wong, Bang Bui, Alex W Hewitt, Guei-Sheung Liu

Conference Proceedings  |  2019  |  Human Gene Therapy

Progressive impairments in executive function in the APP/PS1 model of Alzheimer’s disease as measured by translatable touchscreen testing

A Shepherd, JKH Lim, VHY Wong, AM Zeleznikow-Johnston, L Churilov, CTO Nguyen, BV Bui, AJ Hannan, EL Burrows

Journal article  |  2019

Abstract Executive function deficits in Alzheimer’s disease (AD) occur early in disease progression and may be predictive of cogni..

A tractable preclinical model of optic nerve demyelination

Peter van Wijngaarden, Joseph P Paul, Vickie Hoi Ying Wong, Bang V Bui, Tobias D Merson

Conference Proceedings  |  2019  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Evaluating retinal biomarkers in a mouse model of Parkinson's disease

Christine Tram Oanh Nguyen, Katie Tran, Jeremiah Kah Heng Lim, Vickie Hoi Ying Wong, Ali Shahandeh, Algis J Vingrys, Bang V Bui, David Finkelstein

Conference Proceedings  |  2019  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Response of the Rat Optic Nerve to Acute Intraocular and Intracranial Pressure Changes

Da Zhao, Zheng He, Anna Van Koeverden, Algis J Vingrys, Vickie HY Wong, Jeremiah KH Lim, Christine TO Nguyen, Bang V Bui

Book Chapter  |  2019

A Model of Glaucoma Induced by Circumlimbal Suture in Rats and Mice

Zheng He, Da Zhao, Anna K van Koeverden, Christine T Nguyen, Jeremiah KH Lim, Vickie HY Wong, Algis J Vingrys, Bang Bui

Journal article  |  2018  |  Journal of Visualized Experiments

Reversibility of retinal ganglion cell dysfunction due to chronic IOP elevation.

Da Zhao, Vickie Hoi Ying Wong, Zheng He, Christine Tram Oanh Nguyen, Andrew Ian Jobling, Erica Fletcher, Holly Chinnery, Patricia Jusuf, Jeremiah KH Lim, Algis J Vingrys, Bang V Bui

Conference Proceedings  |  2018  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Age-related changes in the response of retinal structure, function and blood flow to pressure modification in rats

Da Zhao, Christine TO Nguyen, Zheng He, Vickie HY Wong, Anna K van Koeverden, Algis J Vingrys, Bang V Bui

Journal article  |  2018  |  Scientific Reports

Retinal biomarkers provide "insight" into cortical pharmacology and disease

Christine TO Nguyen, Flora Hui, Jason Charng, Shajan Velaedan, Anna K van Koeverden, Jeremiah KH Lim, Zheng He, Vickie HY Wong, Algis J Vingrys, Bang V Bui, Magnus Ivarsson

Journal article  |  2017  |  Pharmacology & Therapeutics

Characterization of the Circumlimbal Suture Model of Chronic IOP Elevation in Mice and Assessment of Changes in Gene Expression of Stretch Sensitive Channels.

Da Zhao, Christine TO Nguyen, Vickie HY Wong, Jeremiah KH Lim, Zheng He, Andrew I Jobling, Erica L Fletcher, Holly R Chinnery, Algis J Vingrys, Bang V Bui

Journal article  |  2017  |  Frontiers in Neuroscience

To consider whether a circumlimbal suture can be used to chronically elevate intraocular pressure (IOP) in mice and to assess its ..

The Eye As a Biomarker for Alzheimer's Disease

Jeremiah KH Lim, Qiao-Xin Li, Zheng He, Algis J Vingrys, Vickie HY Wong, Nicolas Currier, Jamie Mullen, Bang V Bui, Christine TO Nguyen

Journal article  |  2016  |  Frontiers in Neuroscience

Phenotype-based Discovery of 2-[(E)-2-(Quinolin-2-yl)vinyl]phenol as a Novel Regulator of Ocular Angiogenesis

Alison L Reynolds, Yolanda Alvarez, Temitope Sasore, Nora Waghorne, Clare T Butler, Claire Kilty, Andrew J Smith, Carmel McVicar, Vickie HY Wong, Orla Galvin, Stephanie Merrigan, Janina Osman, Gleb Grebnev, Anita Sjolander, Alan W Stitt, Breandan N Kennedy

Journal article  |  2016  |  Journal of Biological Chemistry

Chronic intraocular pressure elevation impairs autoregulatory capacity in streptozotocin-induced diabetic rat retina

Vickie H Wong, James A Armitage, Zheng He, Flora Hui, Algis J Vingrys, Bang V Bui

Journal article  |  2015  |  Ophthalmic and Physiological Optics

Relationship between the Magnitude of Intraocular Pressure during an Episode of Acute Elevation and Retinal Damage Four Weeks later in Rats

Bang V Bui, Abrez H Batcha, Erica Fletcher, Vickie HY Wong, Brad Fortune

Journal article  |  2013  |  PLoS One

Susceptibility of Streptozotocin-Induced Diabetic Rat Retinal Function and Ocular Blood Flow to Acute Intraocular Pressure Challenge

Vickie HY Wong, Algis J Vingrys, Andrew I Jobling, Bang V Bui

Journal article  |  2013  |  Investigative Ophthalmology and Visual Science

Identifying Cell Class Specific Losses from Serially Generated Electroretinogram Components

Christine TO Nguyen, Algis J Vingrys, Vickie HY Wong, Bang V Bui

Journal article  |  2013  |  BioMed Research International

Using the Electroretinogram to Understand How Intraocular Pressure Elevation Affects the Rat Retina

Bang V Bui, Zheng He, Algis J Vingrys, Christine TO Nguyen, Vickie HY Wong, Brad Fortune

Journal article  |  2013  |  Journal of Ophthalmology

SUSCEPTIBILITY OF RETINAL FUNCTION AND OCULAR BLOOD FLOW TO CHRONIC INTRAOCULAR PRESSURE CHALLENGE IN STREPTOZOTOCIN-INDUCED DIABETIC RAT RETINA

Vickie HY Wong, Bang V Bui, Algis J Vingrys

Journal article  |  2012  |  CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Glial and neuronal dysfunction in streptozotocin-induced diabetic rats.

Vickie HY Wong, Algis J Vingrys, Bang V Bui

Journal article  |  2011  |  Journal of Ocular Biology, Diseases, and Informatics

Neuronal dysfunction has been noted very soon after the induction of diabetes by streptozotocin injection in rats. It is not clear..

Clinical and experimental links between diabetes and glaucoma

Vickie HY Wong, Bang V Bui, Algis J Vingrys

Journal article  |  2011  |  Clinical and Experimental Optometry