Andrew Jarnicki

Prime-boost, double-dose influenza vaccine immunity in COPD: a pilot observational study.

Gary P Anderson, Louis B Irving, Andrew Jarnicki, Katherine Kedzierska, Marios Koutsakos, Stephen Kent, Aeron C Hurt, Adam K Wheatley, Thi HO Nguyen, Natale Snape, John W Upham

Journal article  |  2023  |  ERJ Open Res

BACKGROUND: COPD patients are more susceptible to viral respiratory infections and their sequelae, and have intrinsically weaker i..

Gastrointestinal consequences of lipopolysaccharide-induced lung inflammation

Rachel M McQuade, Methma Bandara, Shanti Diwakarla, Lauren Sahakian, Myat Noe Han, Maryam Al Thaalibi, Madeleine R Di Natale, Marsha Tan, Kiera H Harwood, Elena K Schneider-Futschik, Andrew Jarnicki

Journal article  |  2022  |  INFLAMMATION RESEARCH

BACKGROUND: Respiratory inflammation is the body's response to lung infection, trauma or hypersensitivity and is often accompanied..

Adverse roles of mast cell chymase-1 in chronic obstructive pulmonary disease.

Gang Liu, Andrew G Jarnicki, Keshav R Paudel, Wenying Lu, Ridhima Wadhwa, Ashleigh M Philp, Hannelore Van Eeckhoutte, Jacqueline E Marshall, Vamshikrishna Malyla, Angelica Katsifis, Michael Fricker, Nicole G Hansbro, Kamal Dua, Nazanin Z Kermani, Mathew S Eapen, Angelica Tiotiu, K Fan Chung, Gaetano Caramori, Ken Bracke, Ian M Adcock, et al.

Journal article  |  2022  |  Eur Respir J

BACKGROUND: COPD is the third leading cause of death worldwide. Cigarette smoke (CS)-induced chronic inflammation inducing airway ..

Ivacaftor Alters Macrophage and Lymphocyte Infiltration in the Lungs Following Lipopolysaccharide Exposure

Kiera H Harwood, Rachel M McQuade, Andrew Jarnicki, Elena K Schneider-Futschik

Journal article  |  2022  |  ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE

Background and purpose: Cystic fibrosis (CF) is associated with a myriad of respiratory complications including increased suscepti..

Aim2 suppresses cigarette smoke-induced neutrophil recruitment, neutrophil caspase-1 activation and anti-Ly6G-mediated neutrophil depletion.

Chantal Donovan, Richard Y Kim, Izabela Galvao, Andrew G Jarnicki, Alexandra C Brown, Bernadette Jones-Freeman, Henry M Gomez, Ridhima Wadhwa, Elinor Hortle, Ranjith Jayaraman, Haroon Khan, Sophie Pickles, Priyanka Sahu, Vrushali Chimankar, Xiaofan Tu, Md Khadem Ali, Jemma R Mayall, Duc H Nguyen, Kurtis F Budden, Vinod Kumar, et al.

Journal article  |  2022  |  Immunol Cell Biol

Increased inflammasome responses are strongly implicated in inflammatory diseases; however, their specific roles are incompletely ..

Vaccine strain affects seroconversion after influenza vaccination in COPD patients and healthy older people

Natale Snape, Gary P Anderson, Louis B Irving, Andrew G Jarnicki, Aeron C Hurt, Tina Collins, Yang Xi, John W Upham

Journal article  |  2022  |  NPJ VACCINES

Though clinical guidelines recommend influenza vaccination for chronic obstructive pulmonary disease (COPD) patients and other hig..

microRNA-21-mediated SATB1/S100A9/NF-kappa B axis promotes chronic obstructive pulmonary disease pathogenesis

Richard Y Kim, Krishna P Sunkara, Ken R Bracke, Andrew G Jarnicki, Chantal Donovan, Alan C Hsu, Antonio Ieni, Emma L Beckett, Izabela Galvao, Sara Wijnant, Fabio Lm Ricciardolo, Antonino Di Stefano, Tatt Jhong Haw, Gang Liu, Angela L Ferguson, Umamainthan Palendira, Peter A Wark, Griet Conickx, Pieter Mestdagh, Guy G Brusselle, et al.

Journal article  |  2021  |  SCIENCE TRANSLATIONAL MEDICINE

Chronic obstructive pulmonary disease (COPD) is the third leading cause of morbidity and death worldwide. Inhalation of cigarette ..

Time-resolved proteomic profiling of cigarette smoke-induced experimental chronic obstructive pulmonary disease.

David A Skerrett-Byrne, Elizabeth G Bromfield, Heather C Murray, M Fairuz B Jamaluddin, Andrew G Jarnicki, Michael Fricker, Ama T Essilfie, Bernadette Jones, Tatt J Haw, Daniel Hampsey, Amanda L Anderson, Brett Nixon, Rodney J Scott, Peter AB Wark, Matthew D Dun, Philip M Hansbro

Journal article  |  2021  |  Respirology

BACKGROUND AND OBJECTIVE: Chronic obstructive pulmonary disease (COPD) is the third leading cause of illness and death worldwide. ..

Absence of pro-survival A1 has no impact on inflammatory cell survival in vivo during acute lung inflammation and peritonitis

Lahiru Gangoda, Robyn L Schenk, Sarah A Best, Christina Nedeva, Cynthia Louis, Damian B D'Silva, Kirsten Fairfax, Andrew G Jarnicki, Hamsa Puthalakath, Kate D Sutherland, Andreas Strasser, Marco J Herold

Journal article  |  2021  |  CELL DEATH AND DIFFERENTIATION

Inflammation is a natural defence mechanism of the body to protect against pathogens. It is induced by immune cells, such as macro..

Anti-Inflammatory Influences of Cystic Fibrosis Transmembrane Conductance Regulator Drugs on Lung Inflammation in Cystic Fibrosis

Kiera H Harwood, Rachel M McQuade, Andrew Jarnicki, Elena K Schneider-Futschik

Journal article  |  2021  |  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cystic fibrosis (CF) is caused by a defect in the cystic fibrosis transmembrane conductance regulator protein (CFTR) which instiga..