Josef Wagner

Analysis of Hepatitis B virus haplotype diversity detects striking sequence conservation across genotypes and chronic disease phase.

Josef Wagner, Lilly Yuen, Margaret Littlejohn, Vitina Sozzi, Kathy Jackson, Vithika Suri, Susanna Tan, Becket Feierbach, Anuj Gaggar, Patrick Marcellin, Maria Buti Ferret, Harry LA Janssen, Ed Gane, Henry LY Chan, Danni Colledge, Gillian Rosenberg, Julianne Bayliss, Benjamin P Howden, Stephen A Locarnini, Darren Wong, et al.

Journal article  |  2020  |  Hepatology

BACKGROUND: We conducted haplotype analysis of complete hepatitis B virus (HBV) genomes following deep sequencing from 368 patient..

HBV variants are common in the 'immune-tolerant' phase of chronic hepatitis B

Lilly Yuen, Peter A Revill, Gillian Rosenberg, Josef Wagner, Margaret Littlejohn, Julianne Bayliss, Kathy Jackson, Susanna K Tan, Anuj Gaggar, Kathryn Kitrinos, Mani Subramanian, Ed Gane, Henry LY Chan, Xin Li, Scott Bowden, Stephen Locarnini, Alexander Thompson

Journal article  |  2020  |  Journal of Viral Hepatitis

Nucleos(t)ide analouges (NUC) treatment prevents progression of liver fibrosis in subjects with chronic hepatitis B (CHB). However..

Variation of Gut Mucosal Microbiome With Anti-Saccharomyces cerevisiae Antibody Status in Pediatric Crohn Disease.

Shivani Kansal, Anthony G Catto-Smith, Karen Boniface, Sarah Thomas, Donald J Cameron, Mark Oliver, George Alex, Carl D Kirkwood, Josef Wagner

Journal article  |  2019  |  Journal of pediatric gastroenterology and nutrition

OBJECTIVES: Crohn disease (CD) is a chronic relapsing condition possibly caused by a dysbiotic microbiome. Approximately 30% to 60..

Variation of Gut Mucosal Microbiome With Anti-Saccharomyces cerevisiae Antibody Status in Pediatric Crohn Disease

Shivani Kansal, Anthony G Catto-Smith, Karen Boniface, Sarah Thomas, Donald J Cameron, Mark Oliver, George Alex, Carl D Kirkwood, Josef Wagner

Journal article  |  2019  |  Journal of Pediatric Gastroenterology and Nutrition

OBJECTIVES: Crohn's Disease (CD) is a chronic relapsing condition possibly caused by a dysbiotic microbiome. About 30-60% of CD pa..

The composition and functional protein subsystems of the human nasal microbiome in granulomatosis with polyangiitis: a pilot study.

Josef Wagner, Ewan M Harrison, Marcos Martinez Del Pero, Beth Blane, Gert Mayer, Johannes Leierer, Seerapani Gopaluni, Mark A Holmes, Julian Parkhill, Sharon J Peacock, David RW Jayne, Andreas Kronbichler

Journal article  |  2019  |  Microbiome

BACKGROUND: Ear, nose and throat involvement in granulomatosis with polyangiitis (GPA) is frequently the initial disease manifesta..

Multi-Compartment Profiling of Bacterial and Host Metabolites Identifies Intestinal Dysbiosis and Its Functional Consequences in the Critically Ill Child.

Anisha Wijeyesekera, Josef Wagner, Marcus De Goffau, Sarah Thurston, Adilson Rodrigues Sabino, Sara Zaher, Deborah White, Jenna Ridout, Mark J Peters, Padmanabhan Ramnarayan, Ricardo G Branco, M Estee Torok, Frederic Valla, Rosan Meyer, Nigel Klein, Gary Frost, Julian Parkhill, Elaine Holmes, Nazima Pathan

Journal article  |  2019  |  Critical Care Medicine

OBJECTIVES: Adverse physiology and antibiotic exposure devastate the intestinal microbiome in critical illness. Time and cost impl..

The Microbiome in Paediatric Crohn's Disease-A Longitudinal, Prospective, Single-Centre Study

Shivani Kansal, Anthony G Catto-Smith, Karen Boniface, Sarah Thomas, Donald J Cameron, Mark Oliver, George Alex, Carl D Kirkwood, Josef Wagner

Journal article  |  2019  |  Journal of Crohn's and Colitis

BACKGROUND AND AIMS: The gut mucosa is the principal site where Crohn's disease [CD] inflammation occurs. Limited information is a..

Nasal carriage of Staphylococcus pseudintermedius in patients with granulomatosis with polyangiitis.

Andreas Kronbichler, Beth Blane, Mark A Holmes, Josef Wagner, Julian Parkhill, Sharon J Peacock, David RW Jayne, Ewan M Harrison

Journal article  |  2019  |  Rheumatology

Recognizing the reagent microbiome.

Marcus C de Goffau, Susanne Lager, Susannah J Salter, Josef Wagner, Andreas Kronbichler, D Stephen Charnock-Jones, Sharon J Peacock, Gordon CS Smith, Julian Parkhill

Journal article  |  2018  |  Nature Microbiology

Characterization of the fecal virome in dogs with chronic enteropathy

Paloma S Moreno, Josef Wagner, Carl D Kirkwood, James R Gilkerson, Caroline S Mansfield

Journal article  |  2018  |  Veterinary Microbiology

Direct Whole-Genome Sequencing of Cutaneous Strains of Haemophilus ducreyi.

Michael Marks, Maria Fookes, Josef Wagner, Rosanna Ghinai, Oliver Sokana, Yaw-Adu Sarkodie, Anthony W Solomon, David CW Mabey, Nicholas R Thomson

Journal article  |  2018  |  Emerging Infectious Diseases

Haemophilus ducreyi, which causes chancroid, has emerged as a cause of pediatric skin disease. Isolation of H. ducreyi in low-inco..

Diagnostics for Yaws Eradication: Insights From Direct Next-Generation Sequencing of Cutaneous Strains of Treponema pallidum.

Michael Marks, Maria Fookes, Josef Wagner, Robert Butcher, Rosanna Ghinai, Oliver Sokana, Yaw-Adu Sarkodie, Sheila A Lukehart, Anthony W Solomon, David CW Mabey, Nicholas Thomson

Journal article  |  2018  |  Clinical Infectious Diseases

Background: Yaws-like chronic ulcers can be caused by Treponema pallidum subspecies pertenue, Haemophilus ducreyi, or other, still..

Strategies for managing rival bacterial communities: Lessons from burying beetles.

Ana Duarte, Martin Welch, Chris Swannack, Josef Wagner, Rebecca M Kilner

Journal article  |  2018  |  Journal of Animal Ecology

The role of bacteria in animal development, ecology and evolution is increasingly well understood, yet little is known of how anim..

A longitudinal study of the infant nasopharyngeal microbiota: The effects of age, illness and antibiotic use in a cohort of South East Asian children.

Susannah J Salter, Claudia Turner, Wanitda Watthanaworawit, Marcus C de Goffau, Josef Wagner, Julian Parkhill, Stephen D Bentley, David Goldblatt, Francois Nosten, Paul Turner

Journal article  |  2017  |  PLOS Neglected Tropical Diseases

A longitudinal study was undertaken in infants living in the Maela refugee camp on the Thailand-Myanmar border between 2007 and 20..

Characterisation of the canine faecal virome in healthy dogs and dogs with acute diarrhoea using shotgun metagenomics

Paloma S Moreno, Josef Wagner, Caroline S Mansfield, Matthew Stevens, James R Gilkerson, Carl D Kirkwood

Journal article  |  2017  |  PLOS ONE

Protease-activated Receptor 1 Plays a Proinflammatory Role in Colitis by Promoting Th17-related Immunity

Muhammad A Saeed, Garrett Z Ng, Jan Dabritz, Josef Wagner, Louise Judd, Jia-Xi Han, Poshmaal Dhar, Carl D Kirkwood, Philip Sutton

Journal article  |  2017  |  Inflammatory Bowel Diseases

Research benefits of storing genitourinary samples: 16S rRNA sequencing to evaluate vaginal bacterial communities.

Josef Wagner, Sarah Kerry-Barnard, ST Sadiq, Pippa Oakeshott

Journal article  |  2017  |  International Journal of STD & AIDS

Microbial Factors Associated with Postoperative Crohn's Disease Recurrence

Emily K Wright, Michael A Kamm, Josef Wagner, Shu-Mei Teo, Peter De Cruz, Amy L Hamilton, Kathryn J Ritchie, Michael Inouye, Carl D Kirkwood

Journal article  |  2017  |  Journal of Crohn's and Colitis

Recent Advances in Characterizing the Gastrointestinal Microbiome in Crohn's Disease: A Systematic Review

Emily K Wright, Michael A Kamm, Shu Mei Teo, Michael Inouye, Josef Wagner, Carl D Kirkwood

Journal article  |  2015  |  Inflammatory Bowel Diseases

Association between specific mucosa-associated microbiota in Crohn's disease at the time of resection and subsequent disease recurrence: A pilot study

Peter De Cruz, Seungha Kang, Josef Wagner, Michael Buckley, Winnie H Sim, Lani Prideaux, Trevor Lockett, Chris McSweeney, Mark Morrison, Carl D Kirkwood, Michael A Kamm

Journal article  |  2015  |  Journal of Gastroenterology and Hepatology

SNP genotyping of animal and human derived isolates of Mycobacterium avium subsp paratuberculosis

James W Wynne, Christie Beller, Victoria Boyd, Barry Francis, Jacek Gwozdz, Marios Carajias, Hans G Heine, Josef Wagner, Carl D Kirkwood, Wojtek P Michalski

Journal article  |  2014  |  Veterinary Microbiology

TLR4, IL10RA, and NOD2 mutation in paediatric Crohn's disease patients: an association with Mycobacterium avium subspecies paratuberculosis and TLR4 and IL10RA expression

Josef Wagner, Narelle A Skinner, Anthony G Catto-Smith, Donald JS Cameron, Wojtek P Michalski, Kumar Visvanathan, Carl D Kirkwood

Journal article  |  2013  |  MEDICAL MICROBIOLOGY AND IMMUNOLOGY

Bacteriophages in Gut Samples From Pediatric Crohn's Disease Patients: Metagenomic Analysis Using 454 Pyrosequencing

Josef Wagner, Jovana Maksimovic, Gabriella Farries, Winnie H Sim, Ruth F Bishop, Donald J Cameron, Anthony G Catto-Smith, Carl D Kirkwood

Journal article  |  2013  |  Inflammatory Bowel Diseases

Current knowledge and systematic review of viruses associated with Crohn's disease

Josef Wagner, Winnie H Sim, Katherine J Lee, Carl D Kirkwood

Journal article  |  2013  |  Reviews in Medical Virology

Pseudomonas Infection in Children with Early-onset Crohn's Disease: An Association with a Mutation Close to PSMG1

Josef Wagner, Anthony G Catto-Smith, Donald JS Cameron, Carl D Kirkwood

Journal article  |  2013  |  Inflammatory Bowel Diseases

Enteral Nutrition in Crohn's Disease: An Underused Therapy

S Kansal, J Wagner, CD Kirkwood, AG Catto-Smith

Journal article  |  2013  |  Gastroenterology Research and Practice

Gut microbiota at the time of Crohn's resection predicts development of disease recurrence

Peter De Cruz, Seungha Kang, Winnie H Sim, Michael Buckley, Josef Wagner, Lani Prideaux, Mark Morrison, Chris Mcsweeney, Carl Kirkwood, Michael A Kamm

Conference Proceedings  |  2012  |  JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Expression profile of genes involved in pathogenesis of pediatric Crohn's disease

Winnie H Sim, Josef Wagner, Donald J Cameron, Anthony G Catto-Smith, Ruth F Bishop, Carl D Kirkwood

Journal article  |  2012  |  Journal of Gastroenterology and Hepatology

Characterization of the gastrointestinal microbiota in health and inflammatory bowel disease

Peter De Cruz, Lani Prideaux, Josef Wagner, Siew C Ng, Chris McSweeney, Carl Kirkwood, Mark Morrison, Michael A Kamm

Journal article  |  2012  |  Inflammatory Bowel Diseases

Mycobacterium avium Subspecies paratuberculosis in Children with Early-onset Crohn's Disease: A Longitudinal Follow-up Study

Josef Wagner, Winnie Sim, Ruth F Bishop, Anthony G Catto-Smith, Donald JS Cameron, Carl D Kirkwood

Journal article  |  2011  |  Inflammatory Bowel Diseases

Exploring the Zoonotic Potential of Mycobacterium avium Subspecies paratuberculosis through Comparative Genomics

James W Wynne, Tim J Bull, Torsten Seemann, Dieter M Bulach, Josef Wagner, Carl D Kirkwood, Wojtek P Michalski

Journal article  |  2011  |  PLoS One

Prospective Evaluation of the Mucosa-Associated Microbiota Using 454 Pyrosequencing at Crohn's Surgery and 6 Months Later Reveals Loss of Diversity and Specific Phyla Changes Associated With Disease Recurrence

P De Cruz, J Wagner, L Prideaux, CD Kirkwood, M Kamm

Journal article  |  2011  |  Gastroenterology

Identification and Characterisation of Pseudomonas 16S Ribosomal DNA from Ileal Biopsies of Children with Crohn's Disease

Josef Wagner, Kirsty Short, Anthony G Catto-Smith, Don JS Cameron, Ruth F Bishop, Carl D Kirkwood

Journal article  |  2008  |  PLoS One

Differentiation of mouse embryonic stem cells into growth hormone and prolactin expressing cells in vitro

Josef Wagner, Diana Lepore, Paul Thomas

Journal article  |  2007  |  Molecular and Cellular Endocrinology

Survival and differentiation of pituitary colony-forming cells in vivo

Diana A Lepore, Gregory PL Thomas, Kenneth R Knight, Alan J Hussey, Thomas Callahan, Josef Wagner, Wayne A Morrison, Paul Q Thomas

Journal article  |  2007  |  Stem Cells