Josef Wagner

Editorial: baseline hepatitis B virus haplotype number may help predict a functional cure in patients with chronic hepatitis B treated with nucleotide analogues-authors' reply.

Josef Wagner, Margaret Littlejohn, Peter A Revill

Journal article  |  2023  |  Aliment Pharmacol Ther

Hepatitis B virus haplotype number at baseline is a predictive marker of functional cure during antiviral therapy for patients with genotypes A and D HBeAg-positive chronic hepatitis B

Josef Wagner, Lilly Yuen, Margaret Littlejohn, Vitina Sozzi, Kathy Jackson, Ross Martin, Thomas Aeschbacher, Vithika Suri, Susanna K Tan, Becket Feierbach, Anuj Gaggar, Patrick Marcellin, Maria Buti Ferret, Harry LA Janssen, Ed Gane, Niamh Meagher, David J Price, Darren Wong, Alexander T Thompson, Peter A Revill

Journal article  |  2022  |  ALIMENTARY PHARMACOLOGY & THERAPEUTICS

BACKGROUNDS AND AIMS: We investigated associations between hepatitis B virus (HBV) genome-length haplotype number (HN) at baseline..

Secreted hepatitis B virus splice variants differ by HBV genotype and across phases of chronic hepatitis B infection

Olivia Maslac, Josef Wagner, Vitina Sozzi, Hugh Mason, Jenny Svarovskaia, Susanna Tan, Anuj Gaggar, Stephen Locarnini, Lilly Yuen, Margaret Littlejohn, Peter A Revill

Journal article  |  2022  |  JOURNAL OF VIRAL HEPATITIS

Chronic hepatitis B (CHB) is characterized by progression through different phases of hepatitis B virus (HBV) infection and diseas..

Smallpox vaccination induces a substantial increase in commensal skin bacteria that promote pathology and influence the host response.

Evgeniya V Shmeleva, Mercedes Gomez de Agüero, Josef Wagner, Anton J Enright, Andrew J Macpherson, Brian J Ferguson, Geoffrey L Smith

Journal article  |  2022  |  PLoS Pathog

Interactions between pathogens, host microbiota and the immune system influence many physiological and pathological processes. In ..

Gut microbiomes from Gambian infants reveal the development of a non-industrialized Prevotella-based trophic network

Marcus C de Goffau, Amadou T Jallow, Chilel Sanyang, Andrew M Prentice, Niamh Meagher, David J Price, Peter A Revill, Julian Parkhill, Dora IA Pereira, Josef Wagner

Journal article  |  2021  |  NATURE MICROBIOLOGY

Distinct bacterial trophic networks exist in the gut microbiota of individuals in industrialized and non-industrialized countries...

IDENTIFYING VIROLOGICAL FACTORS ASSOCIATED WITH HEPATITIS B VIRUS REBOUND FOLLOWING WITHDRAWAL OF TENOFOVIR THERAPY

Margaret R Littlejohn, Lilly Yuen, Josef Wagner, Vitina Sozzi, Stephen Locarnini, Alexander Thompson, Anuj Gaggar, Maria Buti, Edward J Gane, Patrick Marcellin, Harry LA Janssen, Peter Revill

Conference Proceedings  |  2021  |  HEPATOLOGY

Weight shapes the intestinal microbiome in preterm infants: results of a prospective observational study.

Fardou H Heida, Elisabeth MW Kooi, Josef Wagner, Thi-Yen Nguyen, Jan BF Hulscher, Anne GJF van Zoonen, Arend F Bos, Hermie JM Harmsen, Marcus C de Goffau

Journal article  |  2021  |  BMC Microbiol

BACKGROUND: The intestinal microbiome in preterm infants differs markedly from term infants. It is unclear whether the microbiome ..

An inter-laboratory study to investigate the impact of the bioinformatics component on microbiome analysis using mock communities.

Denise M O'Sullivan, Ronan M Doyle, Sasithon Temisak, Nicholas Redshaw, Alexandra S Whale, Grace Logan, Jiabin Huang, Nicole Fischer, Gregory CA Amos, Mark D Preston, Julian R Marchesi, Josef Wagner, Julian Parkhill, Yair Motro, Hubert Denise, Robert D Finn, Kathryn A Harris, Gemma L Kay, Justin O'Grady, Emma Ransom-Jones, et al.

Journal article  |  2021  |  Sci Rep

Despite the advent of whole genome metagenomics, targeted approaches (such as 16S rRNA gene amplicon sequencing) continue to be va..

Analysis of Hepatitis B Virus Haplotype Diversity Detects Striking Sequence Conservation Across Genotypes and Chronic Disease Phase

Josef Wagner, Lilly Yuen, Margaret Littlejohn, Vitina Sozzi, Kathy Jackson, Vithika Suri, Susanna Tan, Becket Feierbach, Anuj Gaggar, Patrick Marcellin, Maria Buti Ferret, Harry LA Janssen, Ed Gane, Henry LY Chan, Danni Colledge, Gillian Rosenberg, Julianne Bayliss, Benjamin P Howden, Stephen A Locarnini, Darren Wong, et al.

Journal article  |  2021  |  HEPATOLOGY

BACKGROUND AND AIMS: We conducted haplotype analysis of complete hepatitis B virus (HBV) genomes following deep sequencing from 36..

Nasal microbiome research in ANCA-associated vasculitis: Strengths, limitations, and future directions.

Andreas Kronbichler, Ewan M Harrison, Josef Wagner

Journal article  |  2021  |  Comput Struct Biotechnol J

The human nasal microbiome is characterized by biodiversity and undergoes changes during the span of life. In granulomatosis with ..