Renwick Dobson

The protein dynamics of bovine and caprine β-lactoglobulin differ as a function of pH.

Hannah J Mckerchar, Cristina Lento, Rachel Z Bennie, Jennifer M Crowther, Fabian Dolamore, Jolon M Dyer, Stefan Clerens, Davide Mercadante, Derek J Wilson, Renwick CJ Dobson

Journal article  |  2023  |  Food Chem

The properties of milk proteins differ between mammalian species. β-Lactoglobulin (βlg) proteins from caprine and bovine milk are ..

Structure and mechanism of a tripartite ATP-independent periplasmic TRAP transporter.

James S Davies, Michael J Currie, Rachel A North, Mariafrancesca Scalise, Joshua D Wright, Jack M Copping, Daniela M Remus, Ashutosh Gulati, Dustin R Morado, Sam A Jamieson, Michael C Newton-Vesty, Gayan S Abeysekera, Subramanian Ramaswamy, Rosmarie Friemann, Soichi Wakatsuki, Jane R Allison, Cesare Indiveri, David Drew, Peter D Mace, Renwick CJ Dobson

Journal article  |  2023  |  Nat Commun

In bacteria and archaea, tripartite ATP-independent periplasmic (TRAP) transporters uptake essential nutrients. TRAP transporters ..

Self-Driven Capillaric Viscometer for Direct or Cascaded Bar Graph Read-Out of Relative Sample Viscosity

Daniel Mak, R Claude Meffan, Julian Menges, Fabian Dolamore, Conan Fee, Renwick CJ Dobson, Volker Nock

Conference Proceedings  |  2023  |  2023 IEEE 36th International Conference on Micro Electro Mechanical Systems (MEMS)

Laminar flow-based microfluidic systems for molecular interaction analysis—Part 1: Chip development, system operation and measurement setup

SAJ Watkin, A Hashemi, DR Thomson, FG Pearce, RCJ Dobson, VM Nock

Book Chapter  |  2023  |  Methods in Enzymology

The recent advent of laminar flow-based microfluidic systems for molecular interaction analysis has enabled transformative new pro..

DNA storage-from natural biology to synthetic biology.

Elena Bencurova, Aman Akash, Renwick CJ Dobson, Thomas Dandekar

Journal article  |  2023  |  Comput Struct Biotechnol J

Natural DNA storage allows cellular differentiation, evolution, the growth of our children and controls all our ecosystems. Here, ..

Laminar flow-based microfluidic systems for molecular interaction analysis—Part 2: Data extraction, processing and analysis

SAJ Watkin, A Hashemi, DR Thomson, VM Nock, RCJ Dobson, FG Pearce

Journal article  |  2023  |  Methods in Enzymology

The rate at which fluorescently-labeled biomolecules, that are flowing at a constant speed in a microfluidic channel, diffuse into..

On the utility of microfluidic systems to study protein interactions: advantages, challenges, and applications

Serena AJ Watkin, Rachel Z Bennie, Jenna M Gilkes, Volker M Nock, F Grant Pearce, Renwick CJ Dobson

Journal article  |  2022  |  EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

Within the complex milieu of a cell, which comprises a large number of different biomolecules, interactions are critical for funct..

Structure of Reelin repeat 8 and the adjacent C-terminal region.

Liam S Turk, Michael J Currie, Renwick CJ Dobson, Davide Comoletti

Journal article  |  2022  |  Biophys J

Neuronal development and function are dependent in part on the several roles of the secreted glycoprotein Reelin. Endogenous prote..

Sialic Acid Derivatives Inhibit SiaT Transporters and Delay Bacterial Growth

Tiago Bozzola, Mariafrancesca Scalise, Christer U Larsson, Michael C Newton-Vesty, Caterina Rovegno, Ankita Mitra, Jonathan Cramer, Weixiao Yuan Wahlgren, Partha Radhakrishnan Santhakumari, Richard E Johnsson, Oliver Schwardt, Beat Ernst, Rosmarie Friemann, Renwick CJ Dobson, Cesare Indiveri, Jenny Schelin, Ulf J Nilsson, Ulf Ellervik

Journal article  |  2022  |  ACS CHEMICAL BIOLOGY

Antibiotic resistance is a major worldwide concern, and new drugs with mechanistically novel modes of action are urgently needed. ..

Fermentation of plant-based dairy alternatives by lactic acid bacteria

Aimee R Harper, Renwick CJ Dobson, Vanessa K Morris, Gert-Jan Moggre

Journal article  |  2022  |  MICROBIAL BIOTECHNOLOGY

Ethical, environmental and health concerns around dairy products are driving a fast-growing industry for plant-based dairy alterna..