Justin Bedo

CIS controls the functional polarization of GM-CSF-derived macrophages

Shengbo Zhang, Jai Rautela, Naiara G Bediaga, Tatiana B Kolesnik, Yue You, Junli Nie, Laura F Dagley, Justin Bedo, Hanqing Wang, Li Sun, Robyn Sutherland, Elliot Surgenor, Nadia Iannarella, Rhys Allan, Fernando Souza-Fonseca-Guimaraes, Yi Xie, Qike Wang, Yuxia Zhang, Yuekang Xu, Stephen L Nutt, et al.

Journal article  |  2022  |  CELLULAR & MOLECULAR IMMUNOLOGY

The cytokine granulocyte-macrophage-colony stimulating factor (GM-CSF) possesses the capacity to differentiate monocytes into macr..

Epithelial-to-Mesenchymal Transition Supports Ovarian Carcinosarcoma Tumorigenesis and Confers Sensitivity to Microtubule Targeting with Eribulin

Gwo Yaw Ho, Elizabeth L Kyran, Justin Bedo, Matthew J Wakefield, Darren P Ennis, Hasan B Mirza, Cassandra J Vandenberg, Elizabeth Lieschke, Andrew Farrell, Anthony Hadla, Ratana Lim, Genevieve Dall, James E Vince, Ngee Kiat Chua, Olga Kondrashova, Rosanna Upstill-Goddard, Ulla-Maja Bailey, Suzanne Dowson, Patricia Roxburgh, Rosalind M Glasspool, et al.

Journal article  |  2022  |  CANCER RESEARCH

UNLABELLED: Ovarian carcinosarcoma (OCS) is an aggressive and rare tumor type with limited treatment options. OCS is hypothesized ..

From a large-scale genomic analysis of insertion sequences to insights into their regulatory roles in prokaryotes.

Sebastien Tempel, Justin Bedo, Emmanuel Talla

Journal article  |  2022  |  BMC Genomics

BACKGROUND: Insertion sequences (ISs) are mobile repeat sequences and most of them can copy themselves to new host genome location..

Lung Imaging Reveals Stroke-Induced Impairment in Pulmonary Intravascular Neutrophil Function, a Response Exacerbated with Aging.

Shu Wen Wen, Raymond Shim, Pam Hall, Justin Bedo, Jenny L Wilson, Alyce J Nicholls, Michael J Hickey, Connie HY Wong

Journal article  |  2022  |  J Immunol

In stroke patients, infection is a significant contributor to morbidity and mortality. Moreover, older stroke patients show an inc..

Blood-Derived Extracellular Vesicle-Associated miR-3182 Detects Non-Small Cell Lung Cancer Patients

Kekoolani S Visan, Richard J Lobb, Shu Wen Wen, Justin Bedo, Luize G Lima, Sophie Krumeich, Carlos Palma, Kaltin Ferguson, Ben Green, Colleen Niland, Nicole Cloonan, Peter T Simpson, Amy E McCart Reed, Sarah J Everitt, Michael P MacManus, Gunter Hartel, Carlos Salomon, Sunil R Lakhani, David Fielding, Andreas Moeller

Journal article  |  2022  |  CANCERS

With five-year survival rates as low as 3%, lung cancer is the most common cause of cancer-related mortality worldwide. The severi..

svaRetro and svaNUMT: modular packages for annotating retrotransposed transcripts and nuclear integration of mitochondrial DNA in genome sequencing data.

Ruining Dong, Daniel Cameron, Justin Bedo, Anthony T Papenfuss

Journal article  |  2022  |  GigaByte

Nuclear integration of mitochondrial genomes and retrocopied transcript insertion are biologically important but often-overlooked ..

AN INTEGRATED GENOMIC, PROTEOMIC AND IMMUNOPEPTIDOMIC APPROACH TO DISCOVER NOVEL TUMOUR NEOANTIGENS IN AN IMMUNOLOGICALLY COLD OVARIAN CANCER FOR PERSONALISED T-CELL RECEPTOR THERAPY

GY Ho, P Faridi, J Wu, H Barker, T Nguyen-Dumont, J Chang, A Fell, P Eggenhuizen, J Steen, T Manolitsas, S Frentzas, J Bedo, C Vandenberg, T Papenfuss, C Scott, J Ooi, E Segelov

Conference Proceedings  |  2021  |  INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER

Delivering personalized care and research for rare cancers in the increasingly genomic world?

Clare L Scott, Ratana Lim, Damien Kee, Chloe Georgiou, Reece Caldwell, Lia Papadopoulos, Michael S Krasovitsky, Rebecca Tay, Alison Bourne, Cassandra Vandenberg, Genevieve Dall, Kristy Shield-Artin, Amandine Carmagnac, Gayanie Ratnayak, Joshua Tram, Warren Zhou, Justin Bedo, Jocelyn Penington, Layla Zhu, Joseph Vissers, et al.

Conference Proceedings  |  2021  |  ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY

Collateral Sensitivity to beta-Lactam Drugs in Drug-Resistant Tuberculosis Is Driven by the Transcriptional Wiring of BlaI Operon Genes

AS Trigos, BW Goudey, J Bedo, TC Conway, NG Faux, KL Wyres

Journal article  |  2021  |  MSPHERE

The evolution of resistance to one antimicrobial can result in enhanced sensitivity to another, known as "collateral sensitivity."..

Original Research Ductal variant prostate carcinoma is associated with a significantly shorter metastasis-free survival

Ken Chow, Justin Bedo, Andrew Ryan, Dinesh Agarwal, Damien Bolton, Yee Chan, Philip Dundee, Mark Frydenberg, Marc A Furrer, Jeremy Goad, Dennis Gyomber, Uri Hanegbi, Laurence Harewood, Dennis King, Alastair D Lamb, Nathan Lawrentschuk, Peter Liodakis, Daniel Moon, Declan G Murphy, Justin S Peters, et al.

Journal article  |  2021  |  EUROPEAN JOURNAL OF CANCER

BACKGROUND: Ductal adenocarcinoma is an uncommon prostate cancer variant. Previous studies suggest that ductal variant histology m..