Hanwei Cao

IL-23 costimulates antigen-specific MAIT cell activation and enables vaccination against bacterial infection

Huimeng Wang, Lars Kjer-Nielsen, Mai Shi, Criselle D'Souza, Troi J Pediongco, Hanwei Cao, Lyudmila Kostenko, Xin Yi Lim, Sidonia BG Eckle, Bronwyn S Meehan, Tianyuan Zhu, Bingjie Wang, Zhe Zhao, Jeffrey YW Mak, David P Fairlie, Michele WL Teng, Jamie Rossjohn, Di Yu, Barbara Fazekas de St Groth, George Lovrecz, et al.

Journal article  |  2019  |  Science Immunology

Mucosal-associated invariant T (MAIT) cells are activated in a TCR-dependent manner by antigens derived from the riboflavin synthe..

IL-23 co-stimulation drives antigen-specific MAIT cell activation and enables vaccination against bacterial infection

H Wang, L Kjer-Nielsen, M Shi, DC Souza, T Pediongco, H Cao, L Kostenko, X Lim, S Eckle, B Meeha, B Wang, T Zhu, J Mak, D Fairlie, M Teng, J Rossjohn, D Yu, B Groth, J McCluskey, R Strugnell, et al.

Conference Proceedings  |  2019  |  EUROPEAN JOURNAL OF IMMUNOLOGY

Resistance mechanisms and population structure of highly drug resistant Klebsiella in Pakistan during the introduction of the carbapenemase NDM-1

Eva Heinz, Hasan Ejaz, Josefin Bartholdson Scott, Nancy Wang, Shruti Gujaran, Derek Pickard, Jonathan Wilksch, Hanwei Cao, Ikram-ul Haq, Gordon Dougan, Richard A Strugnell

Journal article  |  2019  |  Scientific Reports

An investigation into the Omp85 protein BamK in hypervirulent Klebsiella pneumoniae, and its role in outer membrane biogenesis

Von Vergel L Torres, Eva Heinz, Christopher J Stubenrauch, Jonathan J Wilksch, Hanwei Cao, Ji Yang, Abigail Clements, Rhys A Dunstan, Felicity Alcock, Chaille T Webb, Gordon Dougan, Richard A Strugnell, Iain D Hay, Trevor Lithgow

Journal article  |  2018  |  Molecular Microbiology

Mucosal-Associated Invariant T Cells Augment Immunopathology and Gastritis in Chronic Helicobacter pylori Infection

Criselle D'Souza, Troi Pediongco, Huimeng Wang, Jean-Pierre Y Scheerlinck, Lyudmila Kostenko, Robyn Esterbauer, Andrew W Stent, Sidonia BG Eckle, Bronwyn S Meehan, Richard A Strugnell, Hanwei Cao, Ligong Liu, Jeffrey YW Mak, George Lovrecz, Louis Lu, David P Fairlie, Jamie Rossjohn, James McCluskey, Alison L Every, Zhenjun Chen, et al.

Journal article  |  2018  |  The Journal of Immunology

Phylogenetic Analysis of Klebsiella pneumoniae from Hospitalized Children, Pakistan

Hasan Ejaz, Nancy Wang, Jonathan J Wilksch, Andrew J Page, Hanwei Cao, Shruti Gujaran, Jacqueline A Keane, Trevor Lithgow, Ikram ul-Haq, Gordon Dougan, Richard A Strugnell, Eva Heinz

Journal article  |  2017  |  Emerging Infectious Diseases

Mucosal-associated invariant T-cell activation and accumulation after in vivo infection depends on microbial riboflavin synthesis and co-stimulatory signals

Z Chen, H Wang, C D'Souza, S Sun, L Kostenko, SBG Eckle, BS Meehan, DC Jackson, RA Strugnell, H Cao, N Wang, DP Fairlie, L Liu, DI Godfrey, J Rossjohn, J McCluskey, AJ Corbett

Journal article  |  2017  |  Mucosal Immunology

Genomic analysis of diversity, population structure, virulence, and antimicrobial resistance in Klebsiella pneumoniae, an urgent threat to public health

Kathryn E Holt, Heiman Wertheim, Ruth N Zadoks, Stephen Baker, Chris A Whitehouse, David Dance, Adam Jenney, Thomas R Connor, Li Yang Hsu, Juliette Severin, Sylvain Brisse, Hanwei Cao, Jonathan Wilksch, Claire Gorrie, Mark B Schultz, David J Edwards, Van Nguyen Kinh, Vu Nguyen Trung, Tuyet Dao Trinh, Martijn Mensinke, et al.

Journal article  |  2015  |  Proceedings of the National Academy of Sciences

Analysis of Salmonella enterica Serovar Typhimurium Variable-Number Tandem-Repeat Data for Public Health Investigation Based on Measured Mutation Rates and Whole-Genome Sequence Comparisons

Karolina Dimovski, Hanwei Cao, Odilia LC Wijburg, Richard A Strugnell, Radha K Mantena, Margaret Whipp, Geoff Hogg, Kathryn E Holt

Journal article  |  2014  |  JOURNAL OF BACTERIOLOGY

T-cell activation by transitory neo-antigens derived from distinct microbial pathways

Alexandra J Corbett, Sidonia BG Eckle, Richard W Birkinshaw, Ligong Liu, Onisha Patel, Jennifer Mahony, Zhenjun Chen, Rangsima Reantragoon, Bronwyn Meehan, Hanwei Cao, Nicholas A Williamson, Richard A Strugnell, Douwe Van Sinderen, Jeffrey YW Mak, David P Fairlie, Lars Kjer-Nielsen, Jamie Rossjohn, James McCluskey

Journal article  |  2014  |  Nature

NLRC4 inflammasomes in dendritic cells regulate noncognate effector function by memory CD8( ) T cells

Andreas Kupz, Greta Guarda, Thomas Gebhardt, Leif E Sander, Kirsty R Short, Dimitri A Diavatopoulos, Odilia LC Wijburg, Hanwei Cao, Jason C Waithman, Weisan Chen, Daniel Fernandez-Ruiz, Paul G Whitney, William R Heath, Roy Curtiss, Juerg Tschopp, Richard A Strugnell, Sammy Bedoui

Journal article  |  2012  |  Nature Immunology

MrkH, a Novel c-di-GMP-Dependent Transcriptional Activator, Controls Klebsiella pneumoniae Biofilm Formation by Regulating Type 3 Fimbriae Expression

Jonathan J Wilksch, Ji Yang, Abigail Clements, Jacinta L Gabbe, Kirsty R Short, Hanwei Cao, Rosalia Cavaliere, Catherine E James, Cynthia B Whitchurch, Mark A Schembri, Mary LC Chuah, Zhao-Xun Liang, Odilia L Wijburg, Adam W Jenney, Trevor Lithgow, Richard A Strugnell

Journal article  |  2011  |  PLoS Pathogens