Kate Murphy

Sulforaphane attenuates cancer cell-induced atrophy of C2C12 myotubes.

Wenlan Li, Jennifer Trieu, Ronnie Blazev, Benjamin L Parker, Kate T Murphy, Kristy Swiderski, Gordon S Lynch

Journal article  |  2023  |  Am J Physiol Cell Physiol

Cancer cachexia is common in many cancers and the loss of skeletal muscle mass compromises the response to therapies and quality o..

Oral digoxin effects on exercise performance, K regulation and skeletal muscle Na ,K -ATPase in healthy humans

Simon Sostaric, Aaron C Petersen, Craig A Goodman, Xiaofei Gong, Tai-Juan Aw, Malcolm J Brown, Andrew Garnham, Collene H Steward, Kate T Murphy, Kate A Carey, James Leppik, Steve F Fraser, David Cameron-Smith, Henry Krum, Rodney J Snow, Michael J McKenna

Journal article  |  2022  |  JOURNAL OF PHYSIOLOGY-LONDON

We investigated whether digoxin lowered muscle Na+ ,K+ -ATPase (NKA), impaired muscle performance and exacerbated exercise K+ dist..

Role for Plant-Derived Antioxidants in Attenuating Cancer Cachexia

Wenlan Li, Kristy Swiderski, Kate T Murphy, Gordon S Lynch

Journal article  |  2022  |  ANTIOXIDANTS

Cancer cachexia is the progressive muscle wasting and weakness experienced by many cancer patients. It can compromise the response..

Mechanisms of chemotherapy‐induced muscle wasting in mice with cancer cachexia

Kate T Murphy, Kristy Swiderski, James G Ryall, Jonathan R Davey, Hongwei Qian, Séverine Lamon, Victoria C Foletta, Jennifer Trieu, Annabel Chee, Suzannah J Read, Timur Naim, Paul Gregorevic, Gordon S Lynch

Journal article  |  2022  |  JCSM Rapid Communications

Phosphorylation of ERK and dystrophin S3059 protects against inflammation-associated C2C12 myotube atrophy

Kristy Swiderski, Christopher J Brock, Jennifer Trieu, Annabel Chee, Savant S Thakur, Dale M Baum, Paul Gregorevic, Kate T Murphy, Gordon S Lynch

Journal article  |  2021  |  AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

The dystrophin-glycoprotein complex (DGC) is a multiprotein structure required to maintain muscle fiber membrane integrity, transm..

Research Studies in Twins and Multiple Pregnancy

Janine R Lam, Becky Liu, Kate Murphy, Asma Khalil

Book Chapter  |  2021

Temporal lobe regions essential for preserved picture naming after left temporal epilepsy surgery.

Jeffrey R Binder, Jia-Qing Tong, Sara B Pillay, Lisa L Conant, Colin J Humphries, Manoj Raghavan, Wade M Mueller, Robyn M Busch, Linda Allen, William L Gross, Christopher T Anderson, Chad E Carlson, Mark J Lowe, John T Langfitt, Madalina E Tivarus, Daniel L Drane, David W Loring, Monica Jacobs, Victoria L Morgan, Jane B Allendorfer, et al.

Journal article  |  2020  |  Epilepsia

OBJECTIVE: To define left temporal lobe regions where surgical resection produces a persistent postoperative decline in naming vis..

Twins Research Australia: A New Paradigm for Driving Twin Research

Kate Murphy, Janine Lam, Tessa Cutler, Jess Tyler, Lucas Calais-Ferreira, Shuai Li, Callie Little, Paulo Ferreira, Jeffrey M Craig, Katrina J Scurrah, John L Hopper

Journal article  |  2019  |  TWIN RESEARCH AND HUMAN GENETICS

Twins Research Australia (TRA) is a community of twins and researchers working on health research to benefit everyone, including t..

Mas Receptor Activation Slows Tumor Growth and Attenuates Muscle Wasting in Cancer

Kate T Murphy, Mohammed I Hossain, Kristy Swiderski, Annabel Chee, Timur Naim, Jennifer Trieu, Vanessa Haynes, Suzannah J Read, David I Stapleton, Sarah M Judge, Jose G Trevino, Andrew R Judge, Gordon S Lynch

Journal article  |  2019  |  CANCER RESEARCH

Cancer cachexia is a multifactorial syndrome characterized by a progressive loss of skeletal muscle mass associated with significa..

BGP-15 Improves Aspects of the Dystrophic Pathology in mdx and dko Mice with Differing Efficacies in Heart and Skeletal Muscle

Tahnee L Kennedy, Kristy Swiderski, Kate T Murphy, Stefan M Gehrig, Claire L Curl, Chanchal Chandramouli, Mark A Febbraio, Lea MD Delbridge, Rene Koopman, Gordon S Lynch

Journal article  |  2016  |  AMERICAN JOURNAL OF PATHOLOGY

Duchenne muscular dystrophy is a severe and progressive striated muscle wasting disorder that leads to premature death from respir..