Sophie Paquet-Fifield

Laminin 521 enhances self-renewal via Stat3 activation and promotes tumor progression in Colorectal Cancer.

Yan Qin, Carolyn Shembrey, Jai Smith, Sophie Paquet-Fifield, Corina Behrenbruch, Laura M Beyit, Benjamin NJ Thomson, Alexander G Heriot, Yuan Cao, Frederic Hollande

Journal article  |  2020  |  Cancer Letters

Remodeling of basement membrane proteins contributes to tumor progression towards the metastatic stage. One of these proteins, lam..

Tight Junction Protein Claudin-2 Promotes Self-Renewal of Human Colorectal Cancer Stem-like Cells

Sophie Paquet-Fifield, Shir Lin Koh, Lesley Cheng, Laura M Beyit, Carolyn Shembrey, Christina Molck, Corina Behrenbruch, Marina Papin, Meritxell Gironella, Sophie Guelfi, Ramona Nasr, Fanny Grillet, Michel Prudhomme, Jean-Francois Bourgaux, Antoni Castells, Jean-Marc Pascussi, Alexander G Heriot, Alain Puisieux, Melissa J Davis, Julie Pannequin, et al.

Journal article  |  2018  |  Cancer Research

Surgical stress response and promotion of metastasis in colorectal cancer: a complex and heterogeneous process

Corina Behrenbruch, Carolyn Shembrey, Sophie Paquet-Fifield, Christina Molck, Hyun-Jung Cho, Michael Michael, Benjamin NJ Thomson, Alexander G Heriot, Frederic Hollande

Journal article  |  2018  |  Clinical & Experimental Metastasis

Genome-wide functional analysis reveals central signaling regulators of lymphatic endothelial cell migration and remodeling

Steven P Williams, Adam F Odell, Tara Karnezis, Rae H Farnsworth, Cathryn M Gould, Jason Li, Sophie Paquet-Fifield, Nicole C Harris, Anne Walter, Julia L Gregory, Sara F Lamont, Ruofei Liu, Elena A Takano, Cameron J Nowell, Neil I Bower, Daniel Resnick, Gordon K Smyth, Leigh Coultas, Benjamin M Hogan, Stephen B Fox, et al.

Journal article  |  2017  |  Science Signaling

The fibrinolysis inhibitor alpha(2)-antiplasmin restricts lymphatic remodelling and metastasis in a mouse model of cancer

Sophie Paquet-Fifield, Sally Roufail, You-Fang Zhang, Trifina Sofian, David J Byrne, Paul B Coughlin, Stephen B Fox, Steven A Stacker, Marc G Achen

Journal article  |  2017  |  Growth Factors

Differential Receptor Binding and Regulatory Mechanisms for the Lymphangiogenic Growth Factors Vascular Endothelial Growth Factor (VEGF)-C and -D

Natalia Davydova, Nicole C Harris, Sally Roufail, Sophie Paquet-Fifield, Musarat Ishaq, Victor A Streltsov, Steven P Williams, Tara Karnezis, Steven A Stacker, Marc G Achen

Journal article  |  2016  |  J Biol Chem

High expression of TROP2 characterizes different cell subpopulations in androgen-sensitive and androgen-independent prostate cancer cells

Jinhan Xie, Christina Molck, Sophie Paquet-Fifield, Lisa Butler, Australian Prostate Cancer Bioresource, Erica Sloan, Sabatino Ventura, Frederic Hollande

Journal article  |  2016  |  Oncotarget

VEGF-D promotes pulmonary oedema in hyperoxic acute lung injury

Teruhiko Sato, Sophie Paquet-Fifield, Nicole C Harris, Sally Roufail, Debra J Turner, Yinan Yuan, You-Fang Zhang, Stephen B Fox, Margaret L Hibbs, Jennifer L Wilkinson-Berka, Richard A Williams, Steven A Stacker, Peter D Sly, Marc G Achen

Journal article  |  2016  |  The Journal of Pathology

Intestinal-specific activatable Myb initiates colon tumorigenesis in mice

J Malaterre, L Pereira, T Putoczki, R Millen, S Paquet-Fifield, M Germann, J Liu, D Cheasley, S Sampurno, SA Stacker, MG Achen, RL Ward, P Waring, T Mantamadiotis, M Ernst, RG Ramsay

Journal article  |  2016  |  Oncogene

Mutated but Not Deleted Ovine PrP(C) N-Terminal Polybasic Region Strongly Interferes with Prion Propagation in Transgenic Mice.

Manal Khalifé, Fabienne Reine, Sophie Paquet-Fifield, Johan Castille, Laetitia Herzog, Marthe Vilotte, Mohammed Moudjou, Katayoun Moazami-Goudarzi, Samira Makhzami, Bruno Passet, Olivier Andréoletti, Didier Vilette, Hubert Laude, Vincent Béringue, Jean-Luc Vilotte

Journal article  |  2016  |  Journal of Virology

UNLABELLED: Mammalian prions are proteinaceous infectious agents composed of misfolded assemblies of the host-encoded, cellular pr..

Tumour but not stromal expression of beta 3 integrin is essential, and is required early, for spontaneous dissemination of bone-metastatic breast cancer

Rachel Zoe Carter, Kelli Cristina Micocci, Anthony Natoli, Richard Paul Redvers, Sophie Paquet-Fifield, Ana Carolina Baptista Moreno Martin, Delphine Denoyer, Xiawei Ling, Soo-Hyun Kim, Rebeka Tomasin, Heloisa Selistre-de-Araujo, Robin Lesley Anderson, Normand Pouliot

Journal article  |  2015  |  The Journal of Pathology

Tissues in Different Anatomical Sites Can Sculpt and Vary the Tumor Microenvironment to Affect Responses to Therapy

Christel Devaud, Jennifer A Westwood, Liza B John, Jacqueline K Flynn, Sophie Paquet-Fifield, Connie PM Duong, Carmen SM Yong, Hollie J Pegram, Steven A Stacker, Marc G Achen, Trina J Stewart, Linda A Snyder, Michele WL Teng, Mark J Smyth, Phillip K Darcy, Michael H Kershaw

Journal article  |  2014  |  Molecular Therapy

Vascular Endothelial Growth Factor-d Modulates Caliber and Function of Initial Lymphatics in the Dermis

Sophie Paquet-Fifield, Sidney M Levy, Teruhiko Sato, Ramin Shayan, Tara Karnezis, Natalia Davydova, Cameron J Nowell, Sally Roufail, Gerry Zhi-Ming Ma, You-Fang Zhang, Steven A Stacker, Marc G Achen

Journal article  |  2013  |  Journal of Investigative Dermatology

The Propeptides of VEGF-D Determine Heparin Binding, Receptor Heterodimerization, and Effects on Tumor Biology

Nicole C Harris, Natalia Davydova, Sally Roufail, Sophie Paquet-Fifield, Karri Paavonen, Tara Karnezis, You-Fang Zhang, Teruhiko Sato, Julie Rothacker, Edouard C Nice, Steven A Stacker, Marc G Achen

Journal article  |  2013  |  Journal of Biological Chemistry

Remodeling of the Lymphatic Vasculature during Mouse Mammary Gland Morphogenesis Is Mediated via Epithelial-Derived Lymphangiogenic Stimuli

Kelly L Betterman, Sophie Paquet-Fifield, Marie-Liesse Asselin-Labat, Jane E Visvader, Lisa M Butler, Steven A Stacker, Marc G Achen, Natasha L Harvey

Journal article  |  2012  |  American Journal of Pathology

Functional Characterization of Quiescent Keratinocyte Stem Cells and Their Progeny Reveals a Hierarchical Organization in Human Skin Epidermis

Holger Schlueter, Sophie Paquet-Fifield, Pradnya Gangatirkar, Jason Li, Pritinder Kaur

Journal article  |  2011  |  Stem Cells

A Transplant Model for Human Epidermal Skin Regeneration

Sophie Paquet-Fifield, Richard P Redvers, Normand Pouliot, Pritinder Kaur

Journal article  |  2010  |  Methods in molecular biology (Clifton, N.J.)

E2F7 can regulate proliferation, differentiation, and apoptotic responses in human keratinocytes: implications for cutaneous squamous cell carcinoma formation (vol 69, pg 1800, 2009)

L Endo-Munoz, A Dahler, N Teakle, D Rickwood, M Hazar-Rethinam, I Abdul-Jabbar, S Sommerville, I Dickinson, P Kaur, S Paquet-Fitfield, N Saunders

Journal article  |  2009  |  Cancer Research

A role for pericytes as microenvironmental regulators of human skin tissue regeneration

Sophie Paquet-Fifield, Holger Schlueter, Amy Li, Tara Aitken, Pradnya Gangatirkar, Daniel Blashki, Rachel Koelmeyer, Normand Pouliot, Manuela Palatsides, Sarah Ellis, Nathalie Brouard, Andrew Zannettino, Nick Saunders, Natalie Thompson, Jason Li, Pritinder Kaur

Journal article  |  2009  |  Journal of Clinical Investigation

A cell line infectible by prion strains from different species

M-P Courageot, N Daude, R Nonno, S Paquet, MA Di Bari, A Le Dur, J Chapuis, AF Hill, U Agrimi, H Laude, D Vilette

Journal article  |  2008  |  Journal of General Virology

PrPc does not mediate internalization of PrPSc but is required at an early stage for de novo prion infection of Rov cells.

Sophie Paquet, Nathalie Daude, Marie-Pierre Courageot, Jérôme Chapuis, Hubert Laude, Didier Vilette

Journal article  |  2007  |  Journal of Virology

We have studied the interactions of exogenous prions with an epithelial cell line inducibly expressing PrPc protein and permissive..

Efficient dissemination of prions through preferential transmission to nearby cells.

Sophie Paquet, Christelle Langevin, Jérome Chapuis, Graham S Jackson, Hubert Laude, Didier Vilette

Journal article  |  2007  |  Journal of General Virology

Despite circumstantial evidence that prions can be found extracellularly or at the surface of infected cells, little is known abou..

Establishment of 3D organotypic cultures using human neonatal epidermal cells

Pradnya Gangatirkar, Sophie Paquet-Fifield, Amy Li, Ralph Rossi, Pritinder Kaur

Journal article  |  2007  |  Nature Protocols

Prion proteins from susceptible and resistant sheep exhibit some distinct cell biological features.

Elifsu Sabuncu, Sophie Paquet, Jérome Chapuis, Mohammed Moudjou, Thanh Lan Lai, Jacques Grassi, Udo Baron, Hubert Laude, Didier Vilette

Journal article  |  2005  |  Biochemical and Biophysical Research Communications

It is well established that natural polymorphisms in the coding sequence of the PrP protein can control the expression of prion di..

Prions and exosomes: from PrPc trafficking to PrPsc propagation.

Isabel Porto-Carreiro, Benoît Février, Sophie Paquet, Didier Vilette, Graça Raposo

Journal article  |  2005  |  Blood Cells, Molecules, and Diseases

Exosomes are membrane vesicles released into the extracellular environment upon exocytic fusion of multivesicular endosomes with t..

Prion infection of epithelial Rov cells is a polarized event.

Sophie Paquet, Elifsu Sabuncu, Jean-Louis Delaunay, Hubert Laude, Didier Vilette

Journal article  |  2004  |  Journal of Virology

During prion infections, the cellular glycosylphosphatidylinositol-anchored glycoprotein PrP is converted into a conformational is..

Characterization and functionality of CXCR4 chemokine receptor and SDF-1 in human corneal fibroblasts.

Tristan Bourcier, Tsouria Berbar, Sophie Paquet, Nicolas Rondeau, Frédéric Thomas, Vincent Borderie, Laurent Laroche, William Rostène, France Haour, Alain Lombet

Journal article  |  2003  |  Molecular Vision

PURPOSE: The aim of this study was to investigate whether cultured human corneal fibroblasts express functional chemokine CXCR4 re..

Expression of neurotensin receptors in human corneal keratocytes.

Tristan Bourcier, Nicolas Rondeau, Sophie Paquet, Patricia Forgez, Alain Lombet, François Pouzaud, William Rostène, Vincent Borderie, Laurent Laroche

Journal article  |  2002  |  Investigative Ophthalmology and Visual Science

PURPOSE: The purpose of the study was to investigate whether cultured human keratocytes express the neurotensin receptors (NTR1, N..