Noel Faux

A blood-based signature of cerebrospinal fluid A beta(1-42) status

Benjamin Goudey, Bowen J Fung, Christine Schieber, Noel G Faux, Michael W Weiner, Paul Aisen, Ronald Petersen, Clifford R Jack, William Jagust, John Q Trojanowki, Arthur W Toga, Laurel Beckett, Robert C Green, Andrew J Saykin, John Morris, Leslie M Shaw, Jeffrey Kaye, Joseph Quinn, Lisa Silbert, Betty Lind, et al.

Journal article  |  2019  |  SCIENTIFIC REPORTS

A hybrid approach for automated mutation annotation of the extended human mutation landscape in scientific literature.

Antonio Jimeno Yepes, Andrew MacKinlay, Natalie Gunn, Christine Schieber, Noel Faux, Matthew Downton, Benjamin Goudey, Richard L Martin

Journal article  |  2018  |  AMIA ... Annual Symposium proceedings. AMIA Symposium

As the cost of DNA sequencing continues to fall, an increasing amount of information on human genetic variation is being produced ..

A blood-based signature of cerebral spinal fluid Aβ1–42 status

Benjamin Goudey, Bowen Fung, Christine Schieber, Noel Faux, undefined for the Alzheimer’s Disease Metabolomics Consortium, undefined for the Alzheimer’s Disease Neuroimaging Initiative

Journal article  |  2017

ABSTRACT It is increasingly recognized that Alzheimer’s disease (AD) exists before dementia is present and that shifts in amyloid ..

Cu-II(atsm) improves the neurological phenotype and survival of SOD1(G93A) mice and selectively increases enzymatically active SOD1 in the spinal cord

James B Hilton, Stephen W Mercer, Nastasia KH Lim, Noel G Faux, Gojko Buncic, Joseph S Beckman, Blaine R Roberts, Paul S Donnelly, Anthony R White, Peter J Crouch

Journal article  |  2017  |  SCIENTIFIC REPORTS

Association of Cerebrospinal Fluid Ferritin Level With Preclinical Cognitive Decline in APOE-epsilon 4 Carriers

Scott Ayton, Noel G Faux, Ashley I Bush

Journal article  |  2017  |  JAMA NEUROLOGY

Predicting Alzheimer disease from a blood-based biomarker profile: A 54-month follow-up

Samantha C Burnham, Christopher C Rowe, David Baker, Ashley I Bush, James D Doecke, Noel G Faux, Simon M Laws, Ralph N Martins, Paul Maruff, S Lance Macaulay, Stephanie Rainey-Smith, Greg Savage, David Ames, Colin L Masters, William Wilson, Victor L Villemagne

Journal article  |  2016  |  Neurology

P2-326: Difference in the Rate of Cognitive Change between Individuals with and Without Vascular Risk Factors: A Longitudinal Study

Carolina Restrepo, Michael Saling, Yen Ying Lim, Karra Harrington, Paul Maruff, David Ames, Ashley I Bush, Noel G Faux, Christopher Fowler, Colin L Masters, Ralph N Martins, Christopher C Rowe, Victor L Villemagne, Paul A Yates, Kathryn A Ellis

Journal article  |  2016  |  Alzheimer's & Dementia

Lead and manganese levels in serum and erythrocytes in Alzheimer's disease and mild cognitive impairment: results from the Australian Imaging, Biomarkers and Lifestyle Flagship Study of Ageing

Dominic J Hare, Noel G Faux, Blaine R Roberts, Irene Volitakis, Ralph N Martins, Ashley I Bush

Journal article  |  2016  |  METALLOMICS

Ferritin levels in the cerebrospinal fluid predict Alzheimer's disease outcomes and are regulated by APOE

Scott Ayton, Noel G Faux, Ashley I Bush

Journal article  |  2015  |  NATURE COMMUNICATIONS

Decreased Plasma Iron in Alzheimer's Disease Is Due to Transferrin Desatu ration

Dominic J Hare, James D Doecke, Noel G Faux, Alan Rembach, Irene Volitakis, Christopher J Fowler, Rudolf Grimm, Philip A Doble, Robert A Cherny, Colin L Masters, Ashley I Bush, Blame R Roberts

Journal article  |  2015  |  ACS CHEMICAL NEUROSCIENCE

Peripheral alpha-Defensins 1 and 2 are Elevated in Alzheimer's Disease

Andrew D Watt, Keyla A Perez, Ching-Seng Ang, Paul O'Donnell, Alan Rembach, Kelly K Pertile, Rebecca L Rumble, Brett O Trounson, Christopher J Fowler, Noel G Faux, Colin L Masters, Victor L Villemagne, Kevin J Barnham

Journal article  |  2015  |  JOURNAL OF ALZHEIMERS DISEASE

An anemia of Alzheimer's disease

NG Faux, A Rembach, J Wiley, KA Ellis, D Ames, CJ Fowler, RN Martins, KK Pertile, RL Rumble, B Trounson, CL Masters, AI Bush

Journal article  |  2014  |  MOLECULAR PSYCHIATRY

RESPONSE TO COMMENT ON MOORE ET AL. Increased Risk of Cognitive Impairment in Patients With Diabetes Is Associated With Metformin. Diabetes Care 2013;36:2981-2987

Eileen M Moore, Alastair G Mander, David Ames, Mark A Kotowicz, Ross P Carne, Henry Brodaty, Michael Woodward, Kathryn A Ellis, Ashley I Bush, Noel G Faux, David A Watters

Journal article  |  2014  |  DIABETES CARE

A blood-based predictor for neocortical A beta burden in Alzheimer's disease: results from the AIBL study

SC Burnham, NG Faux, W Wilson, SM Laws, D Ames, J Bedo, Ai Bush, JD Doecke, KA Ellis, R Head, G Jones, H Kiiveri, RN Martins, A Rembach, CC Rowe, O Salvado, SL Macaulay, CL Masters, VL Villemagne

Journal article  |  2014  |  MOLECULAR PSYCHIATRY

Among Vitamin B12 Deficient Older People, High Folate Levels are Associated with Worse Cognitive Function: Combined Data from Three Cohorts

Eileen M Moore, David Ames, Alastair G Mander, Ross P Carne, Henry Brodaty, Michael C Woodward, Karyn Boundy, Kathryn A Ellis, Ashley I Bush, Noel G Faux, Ralph N Martins, Colin L Masters, Christopher C Rowe, Cassandra Szoeke, David A Watters

Journal article  |  2014  |  Journal of Alzheimer's Disease

Changes in plasma amyloid beta in a longitudinal study of aging and Alzheimer's disease

Alan Rembach, Noel G Faux, Andrew D Watt, Kelly K Pertile, Rebecca L Rumble, Brett O Trounson, Christopher J Fowler, Blaine R Roberts, Keyla A Perez, Qiao-Xin Li, Simon M Laws, Kevin Taddei, Stephanie Rainey-Smith, Joanne S Robertson, Manu Vandijck, Hugo Vanderstichele, Kevin J Barnham, Kathryn A Ellis, Cassandra Szoeke, Lance Macaulay, et al.

Journal article  |  2014  |  Alzheimers Dement

Altered transition metal homeostasis in Niemann-Pick disease, type C1

Ya Hui Hung, Noel G Faux, David W Killilea, Nicole Yanjanin, Sally Firnkes, Irene Volitakis, George Ganio, Mark Walterfang, Caroline Hastings, Forbes D Porter, Daniel S Ory, Ashley I Bush

Journal article  |  2014  |  METALLOMICS

Associations between gonadotropins, testosterone and beta amyloid in men at risk of Alzheimer's disease

G Verdile, SM Laws, D Henley, D Ames, AI Bush, KA Ellis, NG Faux, VB Gupta, Q-X Li, CL Masters, KE Pike, CC Rowe, C Szoeke, K Taddei, VL Villemagne, RN Martins

Journal article  |  2014  |  Molecular Psychiatry

Increased risk of cognitive impairment in patients with diabetes is associated with metformin. Diabetes Care 2013;36:2981–2987.

EM Moore, AG Mander, D Ames, MA Kotowicz, RP Carne, H Brodaty, M Woodward, K Boundy, KA Ellis, AI Bush, NG Faux, R Martins, C Szoeke, C Rowe, DA Watters

Journal article  |  2013  |  Diabetes Care

Increased risk of cognitive impairment in patients with diabetes is associated with metformin (vol 36, pg 2981, 2013)

EM Moore, AG Mander, D Ames, MA Kotowicz, RP Carne, H Brodaty, M Woodward, K Boundy, KA Ellis, A Bush, NG Faux, R Martins, C Szoeke, C Rowe, DA Watters

Journal article  |  2013  |  Diabetes Care

Increased Risk of Cognitive Impairment in Patients With Diabetes Is Associated With Metformin

Eileen M Moore, Alastair G Mander, David Ames, Mark A Kotowicz, Ross P Carne, Henry Brodaty, Michael Woodward, Karyn Boundy, Kathryn A Ellis, Ashley I Bush, Noel G Faux, Ralph Martins, Cassandra Szoeke, Christopher Rowe, David A Watters

Journal article  |  2013  |  DIABETES CARE

Longitudinal Analysis of Serum Copper and Ceruloplasmin in Alzheimer's Disease

Alan Rembach, James D Doecke, Blaine R Roberts, Andrew D Watt, Noel G Faux, Irene Volitakis, Kelly K Pertile, Rebecca L Rumble, Brett O Trounson, Christopher J Fowler, William Wilson, Kathryn A Ellis, Ralph N Martins, Christopher C Rowe, Victor L Villemagne, David Ames, Colin L Masters, Ashley I Bush

Journal article  |  2013  |  JOURNAL OF ALZHEIMERS DISEASE

Blood-Based Protein Biomarkers for Diagnosis of Alzheimer Disease

James D Doecke, Simon M Laws, Noel G Faux, William Wilson, Samantha C Burnham, Chiou-Peng Lam, Alinda Mondal, Justin Bedo, Ashley I Bush, Belinda Brown, Karl De Ruyck, Kathryn A Ellis, Christopher Fowler, Veer B Gupta, Richard Head, S Lance Macaulay, Kelly Pertile, Christopher C Rowe, Alan Rembach, Mark Rodrigues, et al.

Journal article  |  2012  |  Archives of Neurology

Imaging and cognitive biomarkers as predictors of progression to Alzheimer's disease

Christopher Rowe, Kathryn Ellis, Belinda Brown, Pierrick Bourgeat, Noel Faux, Ralph Martins, Olivier Salvado, Colin Masters, David Ames, Victor Villemagne

Conference Proceedings  |  2012  |  JOURNAL OF NUCLEAR MEDICINE

SINGLE AMINO ACID AND TRINUCLEOTIDE REPEATS Function and Evolution

Noel Faux

Book Chapter  |  2012  |  Advances in Experimental Medicine and Biology

Single amino acid and trinucleotide repeats function and evolution

N Faux

Journal article  |  2012  |  Advances in Experimental Medicine and Biology

P1-126: Investigating Alzheimer's disease in the blood cellular fraction

Andrew Watt, Keyla Perez, Christopher Rowe, Victor Villemagne, Colin Masters, Kevin Barnham, Noel Faux, Kerryn Pike

Journal article  |  2011  |  Alzheimer's & Dementia

Homocysteine, Vitamin B12, and Folic Acid Levels in Alzheimer's Disease, Mild Cognitive Impairment, and Healthy Elderly: Baseline Characteristics in Subjects of the Australian Imaging Biomarker Lifestyle Study

Noel G Faux, Kathryn A Ellis, Lorine Porter, Chris J Fowler, Simon M Laws, Ralph N Martins, Kelly K Pertile, Alan Rembach, Chris C Rowe, Rebecca L Rumble, Cassandra Szoeke, Kevin Taddei, Tania Taddei, Brett O Trounson, Victor L Villemagne, Vanessa Ward, David Ames, Colin L Masters, Ashley I Bush

Journal article  |  2011  |  Journal of Alzheimer's Disease

Effects of Anticholinergic Drugs on Cognitive Function in Older Australians: Results from the AIBL Study

Gobhathai Sittironnarit, David Ames, Ashley I Bush, Noel Faux, Leon Flicker, Jonathan Foster, Sarah Hilmer, Nicola T Lautenschlager, Paul Maruff, Colin L Masters, Ralph N Martins, Christopher Rowe, Cassandra Szoeke, Kathryn A Ellis

Journal article  |  2011  |  Dementia and Geriatric Cognitive Disorders

Increasing the Predictive Accuracy of Amyloid-beta Blood-Borne Biomarkers in Alzheimer's Disease

Andrew D Watt, Keyla A Perez, Noel G Faux, Kerryn E Pike, Christopher C Rowe, Pierrick Bourgeat, Olivier Salvado, Colin L Masters, Victor L Villemagne, Kevin J Barnham

Journal article  |  2011  |  Journal of Alzheimer's Disease

Larger temporal volume in elderly with high versus low beta-amyloid deposition

Gael Chetelat, Victor L Villemagne, Kerryn E Pike, Jean-Claude Baron, Pierrick Bourgeat, Gareth Jones, Noel G Faux, Kathryn A Ellis, Olivier Salvado, Cassandra Szoeke, Ralph N Martins, David Ames, Colin L Masters, Christopher C Rowe

Journal article  |  2010  |  Brain

A domain level interaction network of amyloid precursor protein and A beta of Alzheimer's disease

Victoria M Perreau, Sandra Orchard, Paul A Adlard, Shayne A Bellingham, Roberto Cappai, Giuseppe D Ciccotosto, Tiffany F Cowie, Peter J Crouch, James A Duce, Genevieve Evin, Noel G Faux, Andrew F Hill, Ya Hui Hung, Simon A James, Qiao-Xin Li, Su San Mok, Deborah J Tew, Anthony R White, Ashley I Bush, Henning Hermjakob, et al.

Journal article  |  2010  |  Proteomics

Blood-Borne Amyloid-beta Dimer Correlates with Clinical Markers of Alzheimer's Disease

Victor L Villemagne, Keyla A Perez, Kerryn E Pike, W Mei Kok, Christopher C Rowe, Anthony R White, Pierrick Bourgeat, Olivier Salvado, Justin Bedo, Craig A Hutton, Noel G Faux, Colin L Masters, Kevin J Barnham

Journal article  |  2010  |  Journal of Neuroscience

Plasma Amyloid-beta as a Biomarker in Alzheimer's Disease: The AIBL Study of Aging

James K Lui, Simon M Laws, Qiao-Xin Li, Victor L Villemagne, David Ames, Belinda Brown, Ashley I Bush, Karl De Ruyck, Jasmin Dromey, Kathryn A Ellis, Noel G Faux, Jonathan Foster, Christopher Fowler, Veer Gupta, Peter Hudson, Katrina Laughton, Colin L Masters, Kelly Pertile, Alan Rembach, Mira Rimajova, et al.

Journal article  |  2010  |  Journal of Alzheimer's Disease

PBT2 Rapidly Improves Cognition in Alzheimer's Disease: Additional Phase II Analyses

Noel G Faux, Craig W Ritchie, Adam Gunn, Alan Rembach, Andrew Tsatsanis, Justin Bedo, John Harrison, Lars Lannfelt, Kaj Blennow, Henrik Zetterberg, Martin Ingelsson, Colin L Masters, Rudolph E Tanzi, Jeffrey L Cummings, Caroline M Herd, Ashley I Bush

Journal article  |  2010  |  Journal of Alzheimer's Disease

O1-06-05: Blood Borne Aβ Dimer Correlates With Clinical Markers of Alzheimer's Disease

Kevin J Barnham, Keyla Perez, Kerryn Pike, Christopher Rowe, Colin Masters, Anthony White, Justin Bedo, Noel Faux, Victor Villemagne

Journal article  |  2009  |  Alzheimer's & Dementia

High-throughput protein structure determination using grid computing

Jason W Schmidberger, Blair Bethwaite, Colin Enticott, Mark A Bate, Steve G Androulakis, Noel Faux, Cyril F Reboul, Jennifer MN Phan, James C Whisstock, Wojtek J Goscinski, Slavisa Garic, David Abramson, Ashley M Buckle

Conference Proceedings  |  2009  |  2009 IEEE International Symposium on Parallel & Distributed Processing

eResearch solutions for high throughput structural biology

N Faux, A Beitz, M Bate, AA Amin, I Atkinson, C Enticott, K Mahmood, M Swift, A Treloar, D Abramson, JC Whisstock, AM Buckle

Conference Proceedings  |  2007  |  Third IEEE International Conference on e-Science and Grid Computing (e-Science 2007)

A common fold mediates vertebrate defense and bacterial attack

Carlos J Rosado, Ashley M Buckle, Ruby HP Law, Rebecca E Butcher, Wan-Ting Kan, Catherina H Bird, Kheng Ung, Kylie A Browne, Katherine Baran, Tanya A Bashtannyk-Puhalovich, Noel G Faux, Wilson Wong, Corrine J Porter, Robert N Pike, Andrew M Ellisdon, Mary C Pearce, Stephen P Bottomley, Jonas Emsley, A Ian Smith, Jamie Rossjohn, et al.

Journal article  |  2007  |  Science

RCPdb: An evolutionary classification and codon usage database for repeat-containing proteins

Noel G Faux, Gavin A Huttley, Khalid Mahmood, Geoffrey I Webb, Maria Garcia de la Banda, James C Whisstock

Journal article  |  2007  |  Genome Research

GABA production by glutamic acid decarboxylase is regulated by a dynamic catalytic loop

Gustavo Fenalti, Ruby HP Law, Ashley M Buckle, Christopher Langendorf, Kellie Tuck, Carlos J Rosado, Noel G Faux, Khalid Mahmood, Christiane S Hampe, J Paul Banga, Matthew Wilce, Jason Schmidberger, Jamie Rossjohn, Ossama El-Kabbani, Robert N Pike, A Ian Smith, Ian R Mackay, Merrill J Rowley, James C Whisstock

Journal article  |  2007  |  Nature Structural & Molecular Biology

Protein Folding Database (PFD 2.0): an online environment for the International Foldeomics Consortium

Kate F Fulton, Mark A Bate, Noel G Faux, Khalid Mahmood, Chris Betts, Ashley M Buckle

Journal article  |  2007  |  NUCLEIC ACIDS RESEARCH

Serpins in prokaryotes

Q Zhang, R Law, AM Buckle, L Cabrita, S McGowan, JA Irving, NG Faux, AM Lesk, SP Bottomley, JC Whisstock

Book Chapter  |  2007

eResearch solutions for high throughput structural biology

Noel Faux, Anthony Beitz, Mark Bate, Abdullah A Amin, Ian Atkinson, Colin Enticott, Khalid Mahmood, Matthew Swift, Andrew Treloar, David Abramson, James C Whisstock, Ashley M Buckle

Conference Proceedings  |  2007  |  Third IEEE International Conference on e-Science and Grid Computing (e-Science 2007)

Managing and mining protein crystallization data

AA Amin, NG Faux, G Fenalti, G Williams, A Bernadou, B Daglish, K Keefe, S Middleton, J Rae, K Tetis, RHP Law, KF Fulton, J Rossjohn, JC Whisstock, AM Buckle

Journal article  |  2006  |  Proteins: Structure, Function, and Bioinformatics

Functional insights from the distribution and role of homopeptide repeat-containing proteins

NG Faux, SP Bottomley, AM Lesk, JA Irving, JR Morrison, MC de la Banda, JC Whisstock

Journal article  |  2005  |  Genome Research

The matrix refolded

AM Buckle, GL Devlin, RA Jodun, KF Fulton, N Faux, JC Whisstock, SP Bottomley

Journal article  |  2005  |  Nature Methods

CLIMS: Crystallography laboratory information management system

KF Fulton, S Ervine, N Faux, R Forster, RA Jodun, W Ly, L Robilliard, J Sonsini, D Whelan, JC Whisstock, AM Buckle

Journal article  |  2004  |  Acta Crystallographica Section D Biological Crystallography