Fiona Sansom

Efficient disruption of the function of the mnuA nuclease gene using the endogenous CRISPR/Cas system in Mycoplasma gallisepticum

Sara M Klose, Nadeeka Wawegama, Fiona M Sansom, Marc S Marenda, Glenn F Browning

Journal article  |  2022  |  VETERINARY MICROBIOLOGY

Mycoplasmas are important animal pathogens, but the functions and roles of many of their genes in pathogenesis remain unclear, in ..

Metagenomic investigation of potential abortigenic pathogens in foetal tissues from Australian horses

Rumana Akter, Charles M El-Hage, Fiona M Sansom, Joan Carrick, Joanne M Devlin, Alistair R Legione

Journal article  |  2021  |  BMC GENOMICS

BACKGROUND: Abortion in horses leads to economic and welfare losses to the equine industry. Most cases of equine abortions are spo..

A Mycoplasma gallisepticum Glycerol ABC Transporter Involved in Pathogenicity

Sara Mahdizadeh, Yumiko Masukagami, Chi-Wen Tseng, Philip F Markham, David P De Souza, Brunda Nijagal, Dedreia Tull, Liliana Tatarczuch, Glenn F Browning, Fiona M Sansom

Journal article  |  2021  |  APPLIED AND ENVIRONMENTAL MICROBIOLOGY

MalF has been shown to be required for virulence in the important avian pathogen Mycoplasma gallisepticum To characterize the func..

Characterisation of putative lactate synthetic pathways of Coxiella burnetii

Janine Hofmann, Mebratu A Bitew, Miku Kuba, David P De Souza, Hayley J Newton, Fiona M Sansom

Journal article  |  2021  |  PLOS ONE

The zoonotic pathogen Coxiella burnetii, the causative agent of the human disease Q fever, is an ever-present danger to global pub..

A 25-year retrospective study of Chlamydia psittaci in association with equine reproductive loss in Australia

Rumana Akter, Fiona M Sansom, Charles M El-Hage, James R Gilkerson, Alistair R Legione, Joanne M Devlin

Journal article  |  2021  |  JOURNAL OF MEDICAL MICROBIOLOGY

Introduction. Chlamydia psittaci is primarily a pathogen of birds but can also cause disease in other species. Equine reproductive..

Mycoplasma bovis mbfN Encodes a Novel LRR Lipoprotein That Undergoes Proteolytic Processing and Binds Host Extracellular Matrix Components

James Y Adamu, Filimon Mitiku, Carol A Hartley, Fiona M Sansom, Marc S Marenda, Philip F Markham, Glenn F Browning, Kelly A Tivendale

Journal article  |  2021  |  JOURNAL OF BACTERIOLOGY

Mycoplasma bovis causes serious infections in ruminants, leading to huge economic losses. Lipoproteins are key components of the m..

Targeted mutagenesis of Mycoplasma gallisepticum using its endogenous CRISPR/Cas system

Sara Mahdizadeh, Fiona M Sansom, Sang-Won Lee, Glenn F Browning, Marc S Marenda

Journal article  |  2020  |  Veterinary Microbiology

New, more efficient methods are needed to facilitate studies of gene function in the mycoplasmas. CRISPR/Cas systems, which provid..

Chlamydia psittaci: a suspected cause of reproductive loss in three Victorian horses

R Akter, AW Stent, FM Sansom, JR Gilkerson, C Burden, JM Devlin, AR Legione, CM El-Hage

Journal article  |  2020  |  AUSTRALIAN VETERINARY JOURNAL

Chlamydia psittaci was detected by PCR in the lung and equine foetal membranes of two aborted equine foetuses and one weak foal fr..

Detection of Coxiella burnetii and equine herpesvirus 1, but not Leptospira spp. or Toxoplasma gondii, in cases of equine abortion in Australia - a 25 year retrospective study

Rumana Akter, Alistair Legione, Fiona M Sansom, Charles M El-Hage, Carol A Hartley, James R Gilkerson, Joanne M Devlin

Journal article  |  2020  |  PLOS ONE

Equine abortion is a cause of severe economic loss to the equine industry. Equine herpesvirus 1 is considered a primary cause of i..

EirA Is a Novel Protein Essential for Intracellular Replication of Coxiella burnetii

Miku Kuba, Nitika Neha, Patrice Newton, Yi Wei Lee, Vicki Bennett-Wood, Abderrahman Hachani, David P De Souza, Brunda Nijagal, Saravanan Dayalan, Dedreia Tull, Malcolm J McConville, Fiona M Sansom, Hayley J Newton

Journal article  |  2020  |  INFECTION AND IMMUNITY

The zoonotic bacterial pathogen Coxiella burnetii is the causative agent of Q fever, a febrile illness which can cause a serious c..