Patrick Reading

IFITM3 and type I interferons are important for the control of influenza A virus replication in murine macrophages.

Sarah L Londrigan, Linda M Wakim, Jeffrey Smith, Anne J Haverkate, Andrew G Brooks, Patrick C Reading

Journal article  |  2019  |  Virology

Abortive infection of macrophages serves as a "dead end" for most seasonal influenza A virus (IAV) strains, and it is likely to co..

Characterization of substitutions in the neuraminidase of A(H7N9) influenza viruses selected following serial passage in the presence of different neuraminidase inhibitors.

R Farrukee, J Butler, PC Reading, AC Hurt

Journal article  |  2019  |  Antiviral Research

Avian A(H7N9) infections in humans have been reported in China since 2013 and are of public health concern due to their severity a..

Downregulation of MHC Class I Expression by Influenza A and B Viruses

Marios Koutsakos, Hamish EG McWilliam, Turgut E Aktepe, Svenja Fritzlar, Patricia T Illing, Nicole A Mifsud, Anthony W Purcell, Steve Rockman, Patrick C Reading, Julian P Vivian, Jamie Rossjohn, Andrew G Brooks, Jason M Mackenzie, Justine D Mintern, Jose A Villadangos, Thi HO Nguyen, Katherine Kedzierska

Journal article  |  2019  |  Frontiers in Immunology

Unraveling the role of the MOV10 RNA helicase during influenza A virus infection

Fernando Villalon-Letelier, Patrick C Reading

Journal article  |  2019  |  Biochemical Journal

Unique Transcriptional Architecture in Airway Epithelial Cells and Macrophages Shapes Distinct Responses following Influenza Virus Infection Ex Vivo

Joel Z Ma, Wy Ching Ng, Luke Zappia, Linden J Gearing, Moshe Olshansky, Kym Pham, Karey Cheong, Arthur Hsu, Stephen J Turner, Odilia Wijburg, Sarah L Londrigan, Andrew G Brooks, Patrick C Reading

Journal article  |  2019  |  Journal of Virology

CSF3R/CD114 mediates infection-dependent transition to severe asthma

Hao Wang, Meaghan FitzPatrick, Nicholas J Wilson, Desiree Anthony, Patrick C Reading, Catherine Satzke, Eileen M Dunne, Paul V Licciardi, Huei Jiunn Seow, Kristy Nichol, Ian M Adcock, Kian Fan Chung, Gary P Anderson, Ross Vlahos, Peter Wark, Steven Bozinovski

Journal article  |  2019  |  Journal of Allergy and Clinical Immunology

Rapid interferon independent expression of IFITM3 following T cell activation protects cells from influenza virus infection

James G Bedford, Meredith O'Keeffe, Patrick C Reading, Linda M Wakim

Journal article  |  2019  |  PLOS ONE

MAIT cells contribute to protection against lethal influenza infection in vivo

Bonnie van Wilgenburg, Liyen Loh, Zhenjun Chen, Troi J Pediongco, Huimeng Wang, Mai Shi, Zhe Zhao, Marios Koutsakos, Simone Nussing, Sneha Sant, Zhongfang Wang, Criselle D'Souza, Xiaoxiao Jia, Catarina F Almeida, Lyudmila Kostenko, Sidonia BG Eckle, Bronwyn S Meehan, Axel Kallies, Dale I Godfrey, Patrick C Reading, et al.

Journal article  |  2018  |  Nature Communications

Characterization of Influenza B Virus Variants with Reduced Neuraminidase Inhibitor Susceptibility

R Farrukee, AE Zarebski, JM McCaw, JD Bloom, PC Reading, AC Hurt

Journal article  |  2018  |  Antimicrobial Agents and Chemotherapy

Safety, immunogenicity and protection of A(H3N2) live attenuated influenza vaccines containing wild-type nucleoprotein in a ferret model

Daniil A Korenkov, Karen L Laurie, Patrick C Reading, Louise A Carolan, Kok Fei Chan, Irina I Isakova-Sivak, Tatiana A Smolonogina, Kanta Subbarao, Ian G Barr, Julie Villanueva, Svetlana Shcherbik, Tatiana Bousse, Larisa G Rudenko

Journal article  |  2018  |  Infection, Genetics and Evolution

MAIT cells contribute to a protective antiviral innate response to influenza infection

Timothy Hinks, Bonnie van Wilgenburg, Liyen Loh, Zhenjun Chen, Troi Pediongco, Huimeng Wang, Mai Shi, Zhe Zhao, Marios Koutsakos, Simone Nussing, Sneha Sant, Zhongfang Wang, Criselle D'Souza, Catarina Almeida, Patrick Reading, Alexandra Corbett, James Mccluskey, Paul Klenerman, Katherine Kedzierska

Conference Proceedings  |  2018  |  Respiratory infections

Changes in Gut Microbiota Prior to Influenza A Virus Infection Do Not Affect Immune Responses in Pups or Juvenile Mice

Eva Fuglsang, Angela Pizzolla, Lukasz Krych, Dennis S Nielsen, Andrew G Brooks, Hanne Frokiaer, Patrick C Reading

Journal article  |  2018  |  Frontiers in Cellular and Infection Microbiology

Investigating Viral Interference Between Influenza A Virus and Human Respiratory Syncytial Virus in a Ferret Model of Infection

Kok Fei Chan, Louise A Carolan, Daniil Korenkov, Julian Druce, James McCaw, Patrick C Reading, Ian G Barr, Karen L Laurie

Journal article  |  2018  |  The Journal of Infectious Diseases

MAIT cells contribute to protection against lethal influenza infection in vivo

Bonnie van Wilgenburg, Liyen Loh, Zhenjun Chen, Troi Pediongco, Huimeng Wang, Mai Shi, Zhe Zhao, Marios Koutsakos, Simone Nussing, Sneha Sant, Zhongfang Wang, Criselle D'Souza, Catarina Almeida, Lyudmila Kostenko, Sidonia BG Eckle, Bronwyn Meehan, Dale Godfrey, Patrick Reading, Alexandra Corbett, James McCluskey, et al.

Journal article  |  2018  |  Nature Communications

Mucosal associated invariant T (MAIT) cells are evolutionarily-conserved, innate-like lymphocytes which are abundant in human lung..

ANTI G-CSFR ANTIBODY TREATMENT SUPPRESSES NEUTROPHILIC AND TYPE-2 LUNG INFLAMMATION IN AN ALLERGIC ASTHMA MODEL WORSENED BY NEONATAL CO-INFECTION

H Wang, M Fitzpatrick, D Anthony, P Reading, N Wilson, C Satzke, E Dunne, P Licciardi, G Anderson, R Vlahos, S Bozinovski

Conference Proceedings  |  2018  |  RESPIROLOGY

AIRWAY EPITHELIAL INNATE IMMUNE RESPONSES TO CORONAVIRUSES

S Loo, K Nichol, A Hsu, S Londrigan, P Reading, N Bartlett, P Wark

Conference Proceedings  |  2018  |  RESPIROLOGY

Infants Harness the Germline against RSV

Annette Fox, Kanta Subbarao, Patrick Reading

Journal article  |  2018  |  Immunity

Evidence for Viral Interference and Cross-reactive Protective Immunity Between Influenza B Virus Lineages

Karen L Laurie, William Horman, Louise A Carolan, Kok Fei Chan, Daniel Layton, Andrew Bean, Dhanasekaran Vijaykrishna, Patrick C Reading, James M Mccaw, Ian G Barr

Journal article  |  2018  |  The Journal of Infectious Diseases

Pathogenesis, Humoral Immune Responses, and Transmission between Cohoused Animals in a Ferret Model of Human Respiratory Syncytial Virus Infection

Kok Fei Chan, Louise A Carolan, Julian Druce, Keith Chappell, Daniel Watterson, Paul Young, Daniil Korenkov, Kanta Subbarao, Ian G Barr, Karen L Laurie, Patrick C Reading

Journal article  |  2018  |  Journal of Virology

Influenza virus detection: driving change in public health laboratories in the Western Pacific Region

Raynal C Squires, Patrick C Reading, Sheena G Sullivan, Ian G Barr, Frank Konings

Journal article  |  2018  |  Western Pacific surveillance and response journal : WPSAR

Infectious Laryngotracheitis Virus Viral Chemokine-Binding Protein Glycoprotein G Alters Transcription of Key Inflammatory Mediators In Vitro and In Vivo

Mauricio JC Coppo, Joanne M Devlin, Alistair R Legione, Paola K Vaz, Sang-Won Lee, Jose A Quinteros, James R Gilkerson, Nino Ficorilli, Patrick C Reading, Amir H Noormohammadi, Carol A Hartley

Journal article  |  2018  |  J Virol

The first external quality assessment of isolation and identification of influenza viruses in cell culture in the Asia Pacific region, 2016

Patrick C Reading, Vivian K Leung, Iwona Buettner, Leah Gillespie, Yi-Mo Deng, Robert Shaw, Natalie Spirason, Angela Todd, Aparna Singh Shah, Frank Konings, Ian G Barr

Journal article  |  2017  |  Journal of Clinical Virology

Host Cell Restriction Factors that Limit Influenza A Infection

Fernando Villalon-Letelier, Andrew G Brooks, Philippa M Saunders, Sarah L Londrigan, Patrick C Reading

Journal article  |  2017  |  Viruses

Extrinsically derived TNF is primarily responsible for limiting antiviral CD8 T cell response magnitude

Kylie M Quinn, Wan-Ting Kan, Katherine A Watson, Brian J Liddicoat, Natasha G Swan, Hayley McQuilten, Alice E Denton, Jasmine Li, Weisan Chen, Lorena E Brown, David C Jackson, Patrick C Reading, Peter C Doherty, Katherine Kedzierska, Lukasz Kedzierski, Stephen J Turner, Nicole L La Gruta

Journal article  |  2017  |  PLOS ONE

Endosomal NOX2 oxidase exacerbates virus pathogenicity and is a target for antiviral therapy

Eunice E To, Ross Vlahos, Raymond Luong, Michelle L Halls, Patrick C Reading, Paul T King, Christopher Chan, Grant R Drummond, Christopher G Sobey, Brad RS Broughton, Malcolm R Starkey, Renee van der Sluis, Sharon R Lewin, Steven Bozinovski, Luke AJ O'Neill, Tim Quach, Christopher JH Porter, Doug A Brooks, John J O'Leary, Stavros Selemidis

Journal article  |  2017  |  Nature Communications

Resident memory CD8( ) T cells in the upper respiratory tract prevent pulmonary influenza virus infection

Angela Pizzolla, Thi HO Nguyen, Jeffrey M Smith, Andrew G Brooks, Katherine Kedzierska, William R Heath, Patrick C Reading, Linda M Wakim

Journal article  |  2017  |  Science Immunology

Nasal-associated lymphoid tissues (NALTs) support the recall but not priming of influenza virus-specific cytotoxic T cells

Angela Pizzolla, Zhongfang Wang, Joanna R Groom, Katherine Kedzierska, Andrew G Brooks, Patrick C Reading, Linda M Wakim

Journal article  |  2017  |  Proceedings of the National Academy of Sciences

Pattern recognition receptor immunomodulation of innate immunity as a strategy to limit the impact of influenza virus

Angela Pizzolla, Jeffery M Smith, Andrew G Brooks, Patrick C Reading

Journal article  |  2017  |  Journal of Leukocyte Biology

DC-SIGN and L-SIGN Are Attachment Factors That Promote Infection of Target Cells by Human Metapneumovirus in the Presence or Absence of Cellular Glycosaminoglycans

Leah Gillespie, Kathleen Gerstenberg, Fernanda Ana-Sosa-Batiz, Matthew S Parsons, Rubaiyea Farrukee, Mark Krabbe, Kirsten Spann, Andrew G Brooks, Sarah L Londrigan, Patrick C Reading

Journal article  |  2016  |  Journal of Virology

Neutralizing inhibitors in the airways of naive ferrets do not play a major role in modulating the virulence of H3 subtype influenza A viruses

Emma R Job, Angela Pizzolla, Thomas Nebl, Kirsty R Short, Yi-Mo Deng, Louise Carolan, Karen L Laurie, Andrew G Brooks, Patrick C Reading

Journal article  |  2016  |  Virology

Influenza-Specific Antibody-Dependent Phagocytosis

Fernanda Ana-Sosa-Batiz, Hillary Vanderven, Sinthujan Jegaskanda, Angus Johnston, Steven Rockman, Karen Laurie, Ian Barr, Patrick Reading, Marit Lichtfuss, Stephen J Kent

Journal article  |  2016  |  PLOS ONE

Neonatal pneumococcal colonisation caused by Influenza A infection alters lung function in adult mice

Meaghan FitzPatrick, Simon G Royce, Shenna Langenbach, Jonathan McQualter, Patrick C Reading, Odilia Wijburg, Gary P Anderson, Alastair Stewart, Jane Bourke, Steven Bozinovski

Journal article  |  2016  |  Scientific Reports

Characterization of the Localized Immune Response in the Respiratory Tract of Ferrets following Infection with Influenza A and B Viruses

Louise A Carolan, Steve Rockman, Kathryn Borg, Teagan Guarnaccia, Patrick Reading, Jennifer Mosse, Anne Kelso, Ian Barr, Karen L Laurie

Journal article  |  2016  |  Journal of Virology

Mapping the pulmonary environment of animals protected from virulent H1N1 influenza infection using the TLR-2 agonist Pam(2)Cys

Edin J Mifsud, Amabel CL Tan, Patrick C Reading, David C Jackson

Journal article  |  2016  |  Immunology and Cell Biology

Endocytic function is critical for influenza A virus infection via DC-SIGN and L-SIGN

Leah Gillespie, Paula Roosendahl, Wy Ching Ng, Andrew G Brooks, Patrick C Reading, Sarah L Londrigan

Journal article  |  2016  |  Scientific Reports

The C-type Lectin Langerin Functions as a Receptor for Attachment and Infectious Entry of Influenza A Virus

Wy Ching Ng, Sarah L Londrigan, Najla Nasr, Anthony L Cunningham, Stuart Turville, Andrew G Brooks, Patrick C Reading

Journal article  |  2016  |  Journal of Virology

Differential neutrophil activation in viral infections: Enhanced TLR-7/8-mediated CXCL8 release in asthma

Francesca SM Tang, David Van Ly, Kirsten Spann, Patrick C Reading, Janette K Burgess, Dominik Hartl, Katherine J Baines, Brian G Oliver

Journal article  |  2016  |  Respirology

Pentraxins and Collectins: Friend or Foe during Pathogen Invasion?

Suan-Sin Foo, Patrick C Reading, Sebastien Jaillon, Alberto Mantovani, Suresh Mahalingam

Journal article  |  2015  |  Trends in Microbiology

Infection of Mouse Macrophages by Seasonal Influenza Viruses Can Be Restricted at the Level of Virus Entry and at a Late Stage in the Virus Life Cycle

Sarah L Londrigan, Kirsty R Short, Joel Ma, Leah Gillespie, Steven P Rockman, Andrew G Brooks, Patrick C Reading

Journal article  |  2015  |  Journal of Virology

Respiratory DC Use IFITM3 to Avoid Direct Viral Infection and Safeguard Virus-Specific CD8( ) T Cell Priming

Giuseppe Infusini, Jeffrey M Smith, He Yuan, Angela Pizzolla, Wy Ching Ng, Sarah L Londrigan, Ashraful Haque, Patrick C Reading, Jose A Villadangos, Linda M Wakim

Journal article  |  2015  |  PLOS ONE

Endogenous Murine BST-2/Tetherin Is Not a Major Restriction Factor of Influenza A Virus Infection

Sarah L Londrigan, Michelle D Tate, Emma R Job, Jessica M Moffat, Linda M Wakim, Christopher A Gonelli, Damien FJ Purcell, Andrew G Brooks, Jose A Villadangos, Patrick C Reading, Justine D Mintern

Journal article  |  2015  |  PLOS ONE

Oseltamivir Prophylaxis Reduces Inflammation and Facilitates Establishment of Cross-Strain Protective T Cell Memory to Influenza Viruses

Nicola L Bird, Matthew R Olson, Aeron C Hurt, Christine M Oshansky, Ding Yuan Oh, Patrick C Reading, Brendon Y Chua, Yilun Sun, Li Tang, Andreas Handel, David C Jackson, Stephen J Turner, Paul G Thomas, Katherine Kedzierska

Journal article  |  2015  |  PLOS ONE

HOW DOES EARLY LIFE VIRAL-INDUCED PNEUMOCOCCAL INFECTION IMPACT THE ADULT MOUSE LUNG?

M Fitzpatrick, J Mcqualter, S Yatmaz, O Wijburg, P Reading, S Langenbach, A Stewart, J Bourke, S Bozinovski

Conference Proceedings  |  2015  |  RESPIROLOGY

Role of Pentraxin 3 in Shaping Arthritogenic Alphaviral Disease: From Enhanced Viral Replication to Immunomodulation

Suan-Sin Foo, Weiqiang Chen, Adam Taylor, Kuo-Ching Sheng, Xing Yu, Terk-Shin Teng, Patrick C Reading, Helen Blanchard, Cecilia Garlanda, Alberto Mantovani, Lisa FP Ng, Lara J Herrero, Suresh Mahalingam

Journal article  |  2015  |  PLOS Pathogens

TaqMan real time RT-PCR assays for detecting ferret innate and adaptive immune responses

Louise A Carolan, Jeff Butler, Steve Rockman, Teagan Guarnaccia, Aeron C Hurt, Patrick Reading, Anne Kelso, Ian Barr, Karen L Laurie

Journal article  |  2014  |  Journal of Virological Methods

Influenza-Specific Antibody-Dependent Cellular Cytotoxicity: Toward a Universal Influenza Vaccine

Sinthujan Jegaskanda, Patrick C Reading, Stephen J Kent

Journal article  |  2014  |  Journal of Immunology

Playing Hide and Seek: How Glycosylation of the Influenza Virus Hemagglutinin Can Modulate the Immune Response to Infection

Michelle D Tate, Emma R Job, Yi-Mo Deng, Vithiagaran Gunalan, Sebastian Maurer-Stroh, Patrick C Reading

Journal article  |  2014  |  Viruses

The Macrophage Galactose-Type Lectin Can Function as an Attachment and Entry Receptor for Influenza Virus

Wy Ching Ng, Stella Liong, Michelle D Tate, Tatsuro Irimura, Kaori Denda-Nagai, Andrew G Brooks, Sarah L Londrigan, Patrick C Reading

Journal article  |  2014  |  Journal of Virology

Antibodies Mediate Formation of Neutrophil Extracellular Traps in the Middle Ear and Facilitate Secondary Pneumococcal Otitis Media

Kirsty R Short, Maren von Koeckritz-Blickwede, Jeroen D Langereis, Keng Yih Chew, Emma R Job, Charles W Armitage, Brandon Hatcher, Kohtaro Fujihashi, Patrick C Reading, Peter W Hermans, Odilia L Wijburg, Dimitri A Diavatopoulos

Journal article  |  2014  |  Infection and Immunity

Neutrophils Respond To Viral Surrogates And Respiratory Viruses

F Tang, D Van Ly, P Reading, K Spann, D Hartl, JK Burgess, JL Black, KJ Baines, BG Oliver

Conference Proceedings  |  2014  |  AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

A Single Amino Acid Substitution in the Hemagglutinin of H3N2 Subtype Influenza A Viruses Is Associated with Resistance to the Long Pentraxin PTX3 and Enhanced Virulence in Mice

Emma R Job, Barbara Bottazzi, Kirsty R Short, Yi-Mo Deng, Alberto Mantovani, Andrew G Brooks, Patrick C Reading

Journal article  |  2014  |  Journal of Immunology

Bacterial Lipopolysaccharide Inhibits Influenza Virus Infection of Human Macrophages and the Consequent Induction of CD8 T Cell Immunity

Kirsty RY Short, Marloes Vissers, Stan de Kleijn, Aldert L Zomer, Katherine Kedzierska, Emma Grant, Patrick C Reading, Peter WM Hernnans, Gerben Ferwerda, Dimitri A Diayatopoulos

Journal article  |  2014  |  Journal of Innate Immunity

Standard Trivalent Influenza Virus Protein Vaccination Does Not Prime Antibody-Dependent Cellular Cytotoxicity in Macaques

Sinthujan Jegaskanda, Thakshila H Amarasena, Karen L Laurie, Tan Hyon-Xhi, Jeff Butler, Matthew S Parsons, Sheilajen Alcantara, Janka Petravic, Miles P Davenport, Aeron C Hurt, Patrick C Reading, Stephen J Kent

Journal article  |  2013  |  Journal of Virology

Age-Associated Cross-reactive Antibody-Dependent Cellular Cytotoxicity Toward 2009 Pandemic Influenza A Virus Subtype H1N1

Sinthujan Jegaskanda, Karen L Laurie, Thakshila H Amarasena, Wendy R Winnall, Marit Kramski, Robert De Rose, Ian G Barr, Andrew G Brooks, Patrick C Reading, Stephen J Kent

Journal article  |  2013  |  Journal of Infectious Diseases

Seasonal influenza vaccine policies, recommendations and use in the World Health Organization's Western Pacific Region.

undefined Members of the Western Pacific Region Global Influenza Surveillance Response System, Dominic Dwyer, Ian Barr, Aeron Hurt, Anne Kelso, Patrick Reading, Sheena Sullivan, Philippe Buchy, Hongjie Yu, Jiandong Zheng, Yuelong Shu, Dayan Wang, undefined Lam, Annette Aguon, Rita Q Oliva, Takato Odagiri, Masato Tashiro, Khebir Verasahib, Mohd Apandi Yusof, Pagbajabyn Nymadawa, et al.

Journal article  |  2013  |  Western Pacific Surveillance and Response Journal

OBJECTIVE: Vaccination is the most effective way to prevent seasonal influenza and its severe outcomes. The objective of our study..

Antigenic Drift of the Pandemic 2009 A(H1N1) Influenza Virus in a Ferret Model

Teagan Guarnaccia, Louise A Carolan, Sebastian Maurer-Stroh, Raphael TC Lee, Emma Job, Patrick C Reading, Stephen Petrie, James M McCaw, Jodie McVernon, Aeron C Hurt, Anne Kelso, Jennifer Mosse, Ian G Barr, Karen L Laurie

Journal article  |  2013  |  PLoS Pathogens

Influenza A virus induced bacterial otitis media is independent of virus tropism for alpha 2,6-linked sialic acid

Kirsty R Short, Marrit N Habets, Jean Payne, Patrick C Reading, Dimitri A Diavatopoulos, Odilia L Wijburg

Journal article  |  2013  |  Virology Journal

Serum Amyloid P Is a Sialylated Glycoprotein Inhibitor of Influenza A Viruses

Emma R Job, Barbara Bottazzi, Brad Gilbertson, Kathryn M Edenborough, Lorena E Brown, Alberto Mantovani, Andrew G Brooks, Patrick C Reading

Journal article  |  2013  |  PLoS One

Addition of Glycosylation to Influenza A Virus Hemagglutinin Modulates Antibody-Mediated Recognition of H1N1 2009 Pandemic Viruses

Emma R Job, Yi-Mo Deng, Kenneth K Barfod, Michelle D Tate, Natalie Caldwell, Scott Reddiex, Sebastian Maurer-Stroh, Andrew G Brooks, Patrick C Reading

Journal article  |  2013  |  Journal of Immunology

Influenza-Induced Inflammation Drives Pneumococcal Otitis Media

Kirsty R Short, Patrick C Reading, Lorena E Brown, John Pedersen, Brad Gilbertson, Emma R Job, Kathryn M Edenborough, Marrit N Habets, Aldert Zomer, Peter WM Hermans, Dimitri A Diavatopoulos, Odilia L Wijburg

Journal article  |  2013  |  Infection and Immunity

Cross-Reactive Influenza-Specific Antibody-Dependent Cellular Cytotoxicity Antibodies in the Absence of Neutralizing Antibodies

Sinthujan Jegaskanda, Emma R Job, Marit Kramski, Karen Laurie, Gamze Isitman, Robert de Rose, Wendy R Winnall, Ivan Stratov, Andrew G Brooks, Patrick C Reading, Stephen J Kent

Journal article  |  2013  |  Journal of Immunology

The "sweet" side of a long pentraxin: how glycosylation affects PTX3 functions in innate immunity and inflammation

Antonio Inforzato, Patrick C Reading, Elisa Barbati, Barbara Bottazzi, Cecilia Garlanda, Alberto Mantovani

Journal article  |  2013  |  Frontiers in Immunology

A novel method linking antigen presentation by human monocyte-derived macrophages to CD8( ) T cell polyfunctionality

Kirsty R Short, Emma J Grant, Marloes Vissers, Patrick C Reading, Dimitri A Diavatopoulos, Katherine Kedzierska

Journal article  |  2013  |  Frontiers in Immunology

The fate of influenza A virus after infection of human macrophages and dendritic cells

Kirsty R Short, Andrew G Brooks, Patrick C Reading, Sarah L Londrigan

Journal article  |  2012  |  Journal of General Virology

Increased Nasopharyngeal Bacterial Titers and Local Inflammation Facilitate Transmission of Streptococcus pneumoniae

Kirsty R Short, Patrick C Reading, Nancy Wang, Dimitri A Diavatopoulos, Odilia L Wijburg

Journal article  |  2012  |  MBIO

Cell-surface receptors on macrophages and dendritic cells for attachment and entry of influenza virus

Sarah L Londrigan, Michelle D Tate, Andrew G Brooks, Patrick C Reading

Journal article  |  2012  |  Journal of Leukocyte Biology

Epidemiological and Virological Characteristics of Influenza in the Western Pacific Region of the World Health Organization, 2006-2010

Ian Barr, Aeron Hurt, Anne Kelso, Patrick Reading, Sovann Ly, Heng Seng, Philippe Buchy, Sam An Ung, Yuelong Shu, Cuiling Xu, Zhen Xu, Dayan Wang, Mike Kama, Prem Singh, Seiichiro Fujisaki, Takato Odagiri, Masato Tashiro, Sibounhom Archkhawongs, Bouaphanh Khamphaphongphanh, Phengta Vongphrachanh, et al.

Journal article  |  2012  |  PLoS ONE

Neutrophils sustain effective CD8( ) T-cell responses in the respiratory tract following influenza infection

Michelle D Tate, Andrew G Brooks, Patrick C Reading, Justine D Mintern

Journal article  |  2012  |  Immunology and Cell Biology

Soluble Host Defense Lectins in Innate Immunity to Influenza Virus

Wy Ching Ng, Michelle D Tate, Andrew G Brooks, Patrick C Reading

Journal article  |  2012  |  Journal of Biomedicine and Biotechnology

Influenza Virus Induces Bacterial and Nonbacterial Otitis Media

Kirsty R Short, Dimitri A Diavatopoulos, Ruth Thornton, John Pedersen, Richard A Strugnell, Andrew K Wise, Patrick C Reading, Odilia L Wijburg

Journal article  |  2011  |  Journal of Infectious Diseases

Specific Sites of N-Linked Glycosylation on the Hemagglutinin of H1N1 Subtype Influenza A Virus Determine Sensitivity to Inhibitors of the Innate Immune System and Virulence in Mice

Michelle D Tate, Andrew G Brooks, Patrick C Reading

Journal article  |  2011  |  Journal of Immunology

Receptor specificity of the influenza virus hemagglutinin modulates sensitivity to soluble collectins of the innate immune system and virulence in mice

Michelle D Tate, Andrew G Brooks, Patrick C Reading

Journal article  |  2011  |  Virology

Glycosylation of the hemagglutinin modulates the sensitivity of H3N2 influenza viruses to innate proteins in airway secretions and virulence in mice

Michelle D Tate, Emma R Job, Andrew G Brooks, Patrick C Reading

Journal article  |  2011  |  Virology

Using Bioluminescent Imaging to Investigate Synergism Between Streptococcus pneumoniae and Influenza A Virus in Infant Mice

Kirsty R Short, Dimitri A Diavatopoulos, Patrick C Reading, Lorena E Brown, Kelly L Rogers, Richard A Strugnell, Odilia LC Wijburg

Journal article  |  2011  |  Journal of Visualized Experiments

Responses of Mouse Airway Epithelial Cells and Alveolar Macrophages to Virulent and Avirulent Strains of Influenza A Virus

Michelle D Tate, Heidi C Schilter, Andrew G Brooks, Patrick C Reading

Journal article  |  2011  |  Viral Immunology

The Role of Neutrophils during Mild and Severe Influenza Virus Infections of Mice

Michelle D Tate, Lisa J Ioannidis, Ben Croker, Lorena E Brown, Andrew G Brooks, Patrick C Reading

Journal article  |  2011  |  PLoS One

Inhibition of lectin-mediated innate host defences in vivo modulates disease severity during influenza virus infection

Michelle D Tate, Andrew G Brooks, Patrick C Reading

Journal article  |  2011  |  Immunology and Cell Biology

N-Linked Glycosylation Facilitates Sialic Acid-Independent Attachment and Entry of Influenza A Viruses into Cells Expressing DC-SIGN or L-SIGN

Sarah L Londrigan, Stuart G Turville, Michelle D Tate, Yi-Mo Deng, Andrew G Brooks, Patrick C Reading

Journal article  |  2011  |  Journal of Virology

Correlation between sialic acid expression and infection of murine macrophages by different strains of influenza virus

Michelle D Tate, Andrew G Brooks, Patrick C Reading

Journal article  |  2011  |  Microbes and Infection

Gr-1( ) cells, but not neutrophils, limit virus replication and lesion development following flank infection of mice with herpes simplex virus type-1

Magdalena Wojtasiak, Danielle L Pickett, Michelle D Tate, Sammy Bedoui, Emma R Job, Paul G Whitney, Andrew G Brooks, Patrick C Reading

Journal article  |  2010  |  Virology

Pandemic H1N1 Influenza A Viruses Are Resistant to the Antiviral Activities of Innate Immune Proteins of the Collectin and Pentraxin Superfamilies

Emma R Job, Yi-Mo Deng, Michelle D Tate, Barbara Bottazzi, Erika C Crouch, Melinda M Dean, Alberto Mantovani, Andrew G Brooks, Patrick C Reading

Journal article  |  2010  |  Journal of Immunology

Depletion of Gr-1( ), but not Ly6G( ), immune cells exacerbates virus replication and disease in an intranasal model of herpes simplex virus type 1 infection

Magdalena Wojtasiak, Danielle L Pickett, Michelle D Tate, Sarah L Londrigan, Sammy Bedoui, Andrew G Brooks, Patrick C Reading

Journal article  |  2010  |  Journal of General Virology

Influenza in the Pacific.

Anne Kelso, Patrick C Reading

Journal article  |  2010  |  Papua and New Guinea medical journal

Influenza A and B viruses cause significant human disease worldwide through regular outbreaks and epidemics of seasonal influenza,..

Influenza viruses differ in ability to infect macrophages and to induce a local inflammatory response following intraperitoneal injection of mice

Patrick C Reading, Paul G Whitney, Danielle L Pickett, Michelle D Tate, Andrew G Brooks

Journal article  |  2010  |  Immunology and Cell Biology

Critical Role of Airway Macrophages in Modulating Disease Severity during Influenza Virus Infection of Mice

Michelle D Tate, Danielle L Pickett, Nico van Rooijen, Andrew G Brooks, Patrick C Reading

Journal article  |  2010  |  Journal of Virology

Macrophage Receptors for Influenza A Virus: Role of the Macrophage Galactose-Type Lectin and Mannose Receptor in Viral Entry

Jacqueline P Upham, Danielle Pickett, Tatsuro Irimura, E Margot Anders, Patrick C Reading

Journal article  |  2010  |  Journal of Virology

Neutrophils Ameliorate Lung Injury and the Development of Severe Disease during Influenza Infection

Michelle D Tate, Yi-Mo Deng, Jessica E Jones, Gary P Anderson, Andrew G Brooks, Patrick C Reading

Journal article  |  2009  |  Journal of Immunology

Loss of a single N-linked glycan from the hemagglutinin of influenza virus is associated with resistance to collectins and increased virulence in mice

Patrick C Reading, Danielle L Pickett, Michelle D Tate, Paul G Whitney, Emma R Job, Andrew G Brooks

Journal article  |  2009  |  Respiratory Research

Memory T cells in nonlymphoid tissue that provide enhanced local immunity during infection with herpes simplex virus

Thomas Gebhardt, Linda M Wakim, Liv Eidsmo, Patrick C Reading, William R Heath, Francis R Carbone

Journal article  |  2009  |  Nature Immunology

The role of neutrophils in the upper and lower respiratory tract during influenza virus infection of mice

Michelle D Tate, Andrew G Brooks, Patrick C Reading

Journal article  |  2008  |  Respiratory Research

Antiviral activity of the long chain pentraxin PTX3 against influenza viruses

Patrick C Reading, Silvia Bozza, Brad Gilbertson, Michelle Tate, Silvia Moretti, Emma R Job, Erika C Crouch, Andrew G Brooks, Lorena E Brown, Barbara Bottazzi, Luigina Romani, Alberto Mantovani

Journal article  |  2008  |  Journal of Immunology

Inhibition of Influenza Viruses By Proteins of the Innate Immune System

P READING, E JOB, M TATE, A BROOKS, B Bottazzi, A Mantovani

Conference Proceedings  |  2008  |  Options for the Control of Influenza VI

IL48, but not IL-12, regulates NK cell activity following intranasal herpes simplex virus type I infection

Patrick C Reading, Paul G Whitney, Daniel P Barr, Magdalena Wojtasiak, Justine D Mintern, Jason Waithman, Andrew G Brooks

Journal article  |  2007  |  Journal of Immunology

A role for plasmacytoid dendritic cells in the rapid IL-18-dependent activation of NK cells following HSV-1 infection

Daniel P Barr, Gabrielle T Belz, Patrick C Reading, Magdalena Wojtasiak, Paul G Whitney, William R Heath, Francis R Carbone, Andrew G Brooks

Journal article  |  2007  |  European Journal of Immunology

Glycosylation as a target for recognition of influenza viruses by the innate immune system

Patrick C Reading, Michelle D Tate, Danielle L Pickett, Andrew G Brooks

Journal article  |  2007  |  Advances in Experimental Medicine and Biology

Glycosylation as a target for recognition of influenza viruses by the innate immune system

PC Reading, MD Tate, DL Pickett, AG Brooks

Conference Proceedings  |  2007  |  Advances in Experimental Medicine and Biology

NK cells contribute to the early clearance of HSV-1 from the lung but cannot control replication in the central nervous system following intranasal infection

PC Reading, PG Whitney, DP Barr, MJ Smyth, AG Brooks

Journal article  |  2006  |  European Journal of Immunology

Neutrophil recruitment and activation following intranasal infection with different influenza viruses

MD Tate, AG Brooks, PC Reading

Conference Proceedings  |  2005  |  TISSUE ANTIGENS

NK cells mediate control of viral replication in the nerves following HSV-1 flank zosteriform infection

M Wojtasiak, PG Whitney, DP Barr, PC Reading, AG Brooks

Conference Proceedings  |  2005  |  TISSUE ANTIGENS

NK cells contribute to the early clearance of HSV-1 from the lung but cannot control replication in the central nervous system following intranasal infection

PG Whitney, PC Reading, DP Barr, M Wojtasiak, MJ Smyth, AG Brooks

Conference Proceedings  |  2005  |  TISSUE ANTIGENS

Plasmacytoid and conventional dendritic cells mediate rapid cytokine-dependent activation of NK cells to herpes simplex virus type 1

DP Barr, PC Reading, M Wojtasiak, PG Whitney, GT Belz, AG Brooks

Conference Proceedings  |  2005  |  TISSUE ANTIGENS

Vaccinia virus protein Toll-like-interleukin-1 A46R targets multiple receptor adaptors and contributes to virulence

J Stack, IR Haga, M Schroder, NW Bartlett, G Maloney, PC Reading, KA Fitzgerald, GL Smith, AG Bowie

Journal article  |  2005  |  Journal of Experimental Medicine

Distinct migrating and nonmigrating dendritic cell populations are involved in MHC class I-restricted antigen presentation after lung infection with virus

GT Belz, CM Smith, L Kleinert, P Reading, A Brooks, K Shortman, FR Carbone, WR Heath

Journal article  |  2004  |  Proceedings of the National Academy of Sciences of the United States of America

The vaccinia virus ketch-like protein C2L affects calcium-independent adhesion to the extracellular matrix and inflammation in a murine intradermal model

MP de Miranda, PC Reading, DC Tscharke, BJ Murphy, GL Smith

Journal article  |  2003  |  Journal of General Virology

Vaccinia virus interleukin-18-binding protein promotes virulence by reducing gamma interferon production and natural killer and T-Cell activity

PC Reading, GL Smith

Journal article  |  2003  |  Journal of Virology

A kinetic analysis of immune mediators in the lungs of mice infected with vaccinia virus and comparison with intradermal infection

PC Reading, GL Smith

Journal article  |  2003  |  Journal of General Virology

Steroid hormone synthesis by vaccinia virus suppresses the inflammatory response to infection

PC Reading, JB Moore, GL Smith

Journal article  |  2003  |  Journal of Experimental Medicine

The poxvirus protein A52R targets toll-like receptor signaling complexes to suppress host defense

MT Harte, IR Haga, G Maloney, P Gray, PC Reading, NW Bartlett, GL Smith, A Bowie, LAJ O'Neill

Journal article  |  2003  |  Journal of Experimental Medicine

A soluble chemokine-binding protein from vaccinia virus reduces virus virulence and the inflammatory response to infection

PC Reading, JA Symons, GL Smith

Journal article  |  2003  |  Journal of Immunology

The vaccinia virus C1 2L protein inhibits mouse IL-18 and promotes virus virulence in the murine intranasal model

JA Symons, E Adams, DC Tscharke, PC Reading, H Waldmann, GL Smith

Journal article  |  2002  |  Journal of General Virology

The vaccinia virus C12L protein inhibits mouse IL-18 and promotes virus virulence in the murine intranasal model

JA Symons, E Adams, DC Tscharke, PC Reading, H Waldmann, GL Smith

Journal article  |  2002  |  Journal of General Virology

Dermal infection with vaccinia virus reveals roles for virus proteins not seen using other inoculation routes

DC Tscharke, PC Reading, GL Smith

Journal article  |  2002  |  Journal of General Virology

Vaccinia virus CrmE encodes a soluble and cell surface tumor necrosis factor receptor that contributes to virus virulence

PC Reading, A Khanna, GL Smith

Journal article  |  2002  |  Virology

Dermal infection with vaccinia virus reveals roles for virus proteins not seen using other inoculation routes

DC Tscharke, PC Reading, GL Smith

Journal article  |  2002  |  Journal of General Virology

Vaccinia virus semaphorin A39R is a 50-55 kDa secreted glycoprotein that affects the outcome of infection in a murine intradermal model

JD Gardner, DC Tscharke, PC Reading, GL Smith

Journal article  |  2001  |  Journal of General Virology

The vaccinia virus A41L protein is a soluble 30 kDa glycoprotein that affects virus virulence

A Ng, DC Tscharke, PC Reading, GL Smith

Journal article  |  2001  |  Journal of General Virology

Lectins in innate host defence against influenza virus

EM Anders, PC Reading, JL Miller

Conference Proceedings  |  2001  |  International Congress Series

Vaccinia virus semaphorin A39R is a 50-55 kDa secreted glycoprotein that affects the outcome of infection in a murine intradermal model

JD Gardner, DC Tscharke, PC Reading, GL Smith

Journal article  |  2001  |  Journal of General Virology

Involvement of the mannose receptor in infection of macrophages by influenza virus

PC Reading, JL Miller, EM Anders

Journal article  |  2000  |  Journal of Virology

Marked differences in the early inflammatory response of mice to different strains of influenza a virus.

PC Reading, JL Miller, EM Anders

Conference Proceedings  |  1999  |  JOURNAL OF LEUKOCYTE BIOLOGY

Antiviral activity of bovine collectins against rotaviruses

PC Reading, U Holmskov, EM Anders

Journal article  |  1998  |  Journal of General Virology

Increased susceptibility of diabetic mice to influenza virus infection: Compromise of collectin-mediated host defense of the lung by glucose?

PC Reading, J Allison, EC Crouch, EM Anders

Journal article  |  1998  |  Journal of Virology

Collectin-mediated antiviral host defense of the lung: Evidence from influenza virus infection of mice

PC Reading, LS Morey, EC Crouch, EM Anders

Journal article  |  1997  |  Journal of Virology

Changes in the hemagglutinin molecule of influenza type A (H3N2) virus associated with increased virulence for mice

CA Hartley, PC Reading, AC Ward, EM Anders

Journal article  |  1997  |  Arch Virol

Role of mannose-binding lectins in innate immunity to influenza virus

EM Anders, PC Reading, LS Morey, CA Hartley

Conference Proceedings  |  1996  |  OPTIONS FOR THE CONTROL OF INFLUENZA III

A serum mannose-binding lectin mediates complement-dependent lysis of influenza virus-infected cells

PC Reading, CA Hartley, RAB Ezekowitz, EM Anders

Journal article  |  1995  |  Biochem Biophys Res Commun

COMPLEMENT-DEPENDENT NEUTRALIZATION OF INFLUENZA-VIRUS BY A SERUM MANNOSE-BINDING LECTIN

EM ANDERS, CA HARTLEY, PC READING, RAB EZEKOWITZ

Journal article  |  1994  |  J Gen Virol

A SERUM MANNOSE-BINDING LECTIN MEDIATES COMPLEMENT-DEPENDENT LYSIS OF INFLUENZA VIRUS-INFECTED CELLS

PC READING, CA HARTLEY, EM ANDERS

Conference Proceedings  |  1993  |  JOURNAL OF LEUKOCYTE BIOLOGY