Nigel Toussaint

Dietary Phosphate Consumption in Australians With Stages 3b and 4 Chronic Kidney Disease

Marguerite Conley, Nicole Lioufas, Nigel D Toussaint, Grahame J Elder, Sunil V Badve, Carmel M Hawley, Elaine M Pascoe, Eugenia Pedagogos, Andrea Valks, Katrina L Campbell

Journal article  |  2021  |  JOURNAL OF RENAL NUTRITION

OBJECTIVE: Dietary phosphate modification is a common therapy to treat hyperphosphatemia in individuals with chronic kidney diseas..

Bone microarchitecture in patients undergoing parathyroidectomy for management of secondary hyperparathyroidism

Irene Ruderman, Chamith S Rajapakse, Angelica Opperman, Patricia L Robertson, Rosemary Masterson, Mark K Tiong, Nigel D Toussaint

Journal article  |  2020  |  BONE REPORTS

Background: Secondary hyperparathyroidism (SHPT) in patients with chronic kidney disease (CKD) leads to complex bone disease, affe..

Practice patterns and predictors of outpatient care following acute kidney injury in an Australian healthcare setting.

Emily J See, David G Ransley, Kevan R Polkinghorne, Nigel Toussaint, Michael Bailey, David Johnson, Ray Robbins, Rinaldo Bellomo

Journal article  |  2020  |  Intern Med J

BACKGROUND: Survivors of acute kidney injury (AKI) are at increased risk of major adverse kidney events and international guidelin..

A Randomized Trial on the Effect of Phosphate Reduction on Vascular End Points in CKD (IMPROVE-CKD)

Nigel D Toussaint, Eugenia Pedagogos, Nicole M Lioufas, Grahame J Elder, Elaine M Pascoe, Sunil V Badve, Andrea Valks, Geoffrey A Block, Neil Boudville, James D Cameron, Katrina L Campbell, Sylvia SM Chen, Randall J Faull, Stephen G Holt, Dana Jackson, Meg J Jardine, David W Johnson, Peter G Kerr, Kenneth K Lau, Lai-Seong Hooi, et al.

Journal article  |  2020  |  JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

BACKGROUND: Hyperphosphatemia is associated with increased fibroblast growth factor 23 (FGF23), arterial calcification, and cardio..

Effect of Sevelamer on Calciprotein Particles in Hemodialysis Patients: The Sevelamer Versus Calcium to Reduce Fetuin-A-Containing Calciprotein Particles in Dialysis (SCaRF) Randomized Controlled Trial

Edward R Smith, Fei Fei M Pan, Tim D Hewitson, Nigel D Toussaint, Stephen G Holt

Journal article  |  2020  |  KIDNEY INTERNATIONAL REPORTS

Introduction: Calciprotein particles (CPPs) are potentially modifiable mediators of phosphate toxicity in patients with kidney dis..

Vascular calcification in skin and subcutaneous tissue in patients with chronic and end-stage kidney disease

Irene Ruderman, Tim D Hewitson, Edward R Smith, Stephen G Holt, Belinda Wigg, Nigel D Toussaint

Journal article  |  2020  |  BMC NEPHROLOGY

BACKGROUND: Vascular calcification (VC) is well described in large- and medium-sized vessels in patients with chronic kidney disea..

A tRial Evaluating Mid Cut-Off Value Membrane Clearance of Albumin and Light Chains in HemoDialysis Patients: A Safety Device Study

Rathika Krishnasamy, Carmel M Hawley, Meg J Jardine, Matthew A Roberts, Yeoungjee Cho, Muhgeot Wong, Anne Heath, Craig L Nelson, Shaundeep Sen, Peter F Mount, Elaine M Pascoe, Liza A Vergara, Peta-Anne Paul-Brent, Nigel D Toussaint, David W Johnson, Colin A Hutchison

Journal article  |  2020  |  BLOOD PURIFICATION

BACKGROUND: A new class of dialysis membrane, the mid cut-off (MCO) dialyzer, has been developed to improve the clearance of uremi..

Residual kidney function in nocturnal vs conventional haemodialysis patients: a prospective observational study

Lee Skeat, Rosemary Masterson, Alwie C Tjipto, Connie Karschimkus, Nigel D Toussaint

Journal article  |  2020  |  International Urology and Nephrology

Background Residual kidney function (RKF) provides substantial volume and solute clearance even after dialysis initiation. Preserv..

SUN-094 A RANDOMISED CROSS-OVER TRIAL OF THE EFFECTS OF CALCIUM CARBONATE AND SEVELAMER PHOSPHATE BINDERS ON CALCIPROTEIN PARTICLES IN PREVALENT HAEMODIALYSIS PATIENTS

FF Pan, ER Smith, TD Hewitson, B Wigg, PJ Champion de Crespigny, ND Toussaint, SG Holt

Report  |  2020  |  Kidney International Reports

Aortic Calcification and Arterial Stiffness Burden in a Chronic Kidney Disease Cohort with High Cardiovascular Risk: Baseline Characteristics of the Impact of Phosphate Reduction On Vascular End-Points in Chronic Kidney Disease Trial

Nicole M Lioufas, Eugenia Pedagogos, Carmel M Hawley, Elaine M Pascoe, Grahame J Elder, Sunil Badve, Andrea Valks, Nigel D Toussaint

Journal article  |  2020  |  AMERICAN JOURNAL OF NEPHROLOGY

Chronic kidney disease (CKD) is associated with excess cardiovascular morbidity and mortality compared to the general population. ..