Dr Mercuri is an experienced research scientist who has worked as a research assistant and research fellow/officer over the last 16 years in areas of immunology, endocrinology, arthritis, and cancer. Dr Mercuri undertook her PhD studies examining aggrecan degradation by metalloproteinases, within the Orthopaedic Research Unit, Department of Paediatrics at the Royal Children's Hospital, Parkville.
Dr Mercuri was then awarded a Wellcome Trust Travelling Fellowship, to pursue her research in examining the roles of ADAMs in the shedding of the HGF receptor at the School of Biological Studies, University of East Anglia, UK. On her return to Australia Dr Mercuri was awarded a NH&MRC Part Time Training Fellowship within the Dept. of Surgery, St Vincent's Hospital, University of Melbourne, studying collagen regulation of the Matris Metalloproteinases in breast cancer metastasis. At this point, Dr Mercuri expanded her career options by incorporating and gaining experience in Project Management within the department of Microbiology and Immunology at the University of Melbourne. Whilst working as a Project Officer, Dr Mercuri also took on another part-time role at the Burnet Institute as the Microbicide Research Officer. Her role was to facilitate and manage the Burnet's role within a NIH funded Microbicide Development Consortium. As part of the Clinical Trial Administration team, Dr Mercuri was involved and underwent training in the conduct and preparation of a large multi-institutional HIV clinical trial.
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Francesca Mercuri's highlights
Francesca Mercuri's selected work
The type I collagen induction of MT1-MMP-mediated MMP-2 activation is repressed by alpha V..
Type I collagen abrogates the clathrin-mediated internalization of membrane type 1 matrix ..
Displaying the 17 most recent projects by Francesca Mercuri.
Displaying the 13 most recent scholarly works by Francesca Mercuri.
Inactivated Influenza Vaccine That Provides Rapid, Innate-Immune-System-Mediated Protection and Subsequent Long-Term Adaptive Immunity
Brendon Y Chua, Chinn Yi Wong, Edin J Mifsud, Kathryn M Edenborough, Toshiki Sekiya, Amabel CL Tan, Francesca Mercuri, Steve Rockman, Weisan Chen, Stephen J Turner, Peter C Doherty, Anne Kelso, Lorena E Brown, David C Jackson
Journal article | 2015 | mBio
The type I collagen induction of MT1-MMP-mediated MMP-2 activation is repressed by alpha V beta 3 integrin in human breast cancer cells
Kulrut Borrirukwanit, Marc A Lafleur, Francesca A Mercuri, Tony Blick, John T Price, Rafael Fridman, Joseph J Pereira, Vijittra Leardkamonkarn, Erik W Thompson
Journal article | 2007 | Matrix Biology
Mutations in the interglobular domain of aggrecan alter matrix metalloproteinase and aggrecanase cleavage patterns - Evidence that matrix metalloproteinase cleavage interferes with aggrecanase activity
FA Mercuri, RA Maciewicz, J Tart, K Last, AJ Fosang
Journal article | 2000 | Journal of Biological Chemistry
Localization of messenger ribonucleic acid for insulin-like growth factor-binding proteins in human skin by in situ hybridization.
JA Batch, FA Mercuri, SR Edmondson, GA Werther
Journal article | 1994 | The Journal of Clinical Endocrinology & Metabolism
The role of the insulin-like growth factors (IGFs) in human skin physiology has been increasingly recognized, although relatively ..
Identification, localization, and regulation of insulin-like growth factor binding proteins and their messenger ribonucleic acids in the newborn rat olfactory bulb.
VC Russo, SR Edmondson, FA Mercuri, CR Buchanan, GA Werther
Journal article | 1994 | Endocrinology
Insulin-like growth factor binding proteins (IGFBPs) have been identified in most tissues, including the central nervous system, w..