Chin Tan

117 High-plex spatial proteomic profiling of immunotherapy response groups in head and neck cancer identifies tissue signatures associated with therapy response

Arutha Kulasinghe, Habib Sadeghirad, Ning Liu, James Monkman, Chin Wee Tan, Caroline Cooper, Sarah Church, Fabian Schneider, Jeppe Thaagard, James Mansfield, Kenneth O’byrne, Melissa Davis, Brett Hughes

Conference Proceedings  |  2022  |  Regular and Young Investigator Award Abstracts

923 Deep single-cell, proteogenomic insights from SARS-CoV-2 infected lung tissues

Arutha Kulasinghe, Chin Wee Tan, Ning Liu, James Monkman, Emily Killingbeck, Youngmi Kim, Liuliu Pan, Tony Blick, Dharmesh Bhuva, Kristen Feher, Michael Leon, Mark Gregory, Kirsty Short, Fernando Guimaraes, Michael Rhodes, Gabrielle Belz, Melissa Davis

Conference Proceedings  |  2022  |  Regular and Young Investigator Award Abstracts

Transcriptomic profiling of cardiac tissues from SARS-CoV-2 patients identifies DNA damage

Arutha Kulasinghe, Ning Liu, Chin Wee Tan, James Monkman, Jane E Sinclair, Dharmesh D Bhuva, David Godbolt, Liuliu Pan, Andy Nam, Habib Sadeghirad, Kei Sato, Gianluigi Li Bassi, Ken O'Byrne, Camila Hartmann, Anna Flavia Ribeiro Dos Santos Miggiolaro, Gustavo Lenci Marques, Lidia Zytynski Moura, Derek Richard, Mark Adams, Lucia de Noronha, et al.

Journal article  |  2022  |  IMMUNOLOGY

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is known to present with pulmonary and extra-pulmonary organ comp..

Profiling of lung SARS-CoV-2 and influenza virus infection dissects virus-specific host responses and gene signatures

Arutha Kulasinghe, Chin Wee Tan, Anna Flavia Ribeiro Dos Santos Miggiolaro, James Monkman, Habib SadeghiRad, Dharmesh D Bhuva, Jarbas da Silva Motta Junior, Caroline Busatta Vaz de Paula, Seigo Nagashima, Cristina Pellegrino Baena, Paulo Souza-Fonseca-Guimaraes, Lucia de Noronha, Timothy McCulloch, Gustavo Rodrigues Rossi, Caroline Cooper, Benjamin Tang, Kirsty R Short, Melissa J Davis, Fernando Souza-Fonseca-Guimaraes, Gabrielle T Belz, et al.

Journal article  |  2022  |  EUROPEAN RESPIRATORY JOURNAL

BACKGROUND: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which emerged in late 2019 has spread globally, causi..

IFI27 transcription is an early predictor for COVID-19 outcomes, a multi-cohort observational study.

Maryam Shojaei, Amir Shamshirian, James Monkman, Laura Grice, Minh Tran, Chin Wee Tan, Siok Min Teo, Gustavo Rodrigues Rossi, Timothy R McCulloch, Marek Nalos, Maedeh Raei, Alireza Razavi, Roya Ghasemian, Mobina Gheibi, Fatemeh Roozbeh, Peter D Sly, Kirsten M Spann, Keng Yih Chew, Yanshan Zhu, Yao Xia, et al.

Journal article  |  2022  |  Front Immunol

PURPOSE: Robust biomarkers that predict disease outcomes amongst COVID-19 patients are necessary for both patient triage and resou..

P799: SPATIAL ANALYSIS IDENTIFIES A SPECTRUM OF IMMUNE DYSREGULATION IN ACQUIRED BONE MARROW FAILURE CONDITIONS

R Koldej, A Prabahran, CW Tan, M Davis, D Ritchie

Journal article  |  2022  |  HemaSphere

Transplantable programmed death ligand 1 expressing gastroids from gastric cancer prone Nfkb1(-/-) mice

Jun T Low, Gwo-Yaw Ho, Mark Scott, Chin Wee Tan, Lachlan Whitehead, Kathy Barber, Hon YK Yip, Johanna F Dekkers, Yumiko Hirokawa, John Silke, Antony W Burgess, Andreas Strasser, Tracy L Putoczki, Lorraine A O'Reilly

Journal article  |  2021  |  CELL DEATH & DISEASE

SOX9 Defines Distinct Populations of Cells in SHH Medulloblastoma but Is Not Required for Math1-Driven Tumor Formation

Christelle Adolphe, Amanda Millar, Marija Kojic, Deborah S Barkauskas, Anders Sundstrom, Fredrik J Swartling, Soroor Hediyeh-Zadeh, Chin Wee Tan, Melissa J Davis, Laura A Genovesi, Brandon J Wainwright

Journal article  |  2021  |  MOLECULAR CANCER RESEARCH

Medulloblastoma is the most common malignant pediatric brain tumor and there is an urgent need for molecularly targeted and subgro..

Dissection of the bone marrow microenvironment in hairy cell leukaemia identifies prognostic tumour and immune related biomarkers

Rachel M Koldej, Ashvind Prabahran, Chin Wee Tan, Ashley P Ng, Melissa J Davis, David S Ritchie

Journal article  |  2021  |  SCIENTIFIC REPORTS

Hairy cell leukaemia (HCL) is a rare CD20+ B cell malignancy characterised by rare "hairy" B cells and extensive bone marrow (BM) ..

Low-viscosity matrix suspension culture enables scalable analysis of patient-derived organoids and tumoroids from the large intestine

Yumiko Hirokawa, Jordan Clarke, Michelle Palmieri, Tao Tan, Dmitri Mouradov, Shan Li, Cong Lin, Fuqiang Li, Huijuan Luo, Kui Wu, Maree Faux, Chin Wee Tan, Margaret Lee, Grace Gard, Peter Gibbs, Antony W Burgess, Oliver M Sieber

Journal article  |  2021  |  COMMUNICATIONS BIOLOGY

Cell embedment into a solid support matrix is considered essential for the culture of intestinal epithelial organoids and tumoroid..