Rene Koopman

Iron accumulation in skeletal muscles of old mice is associated with impaired regeneration after ischaemia-reperfusion damage

Francesca M Alves, Kai Kysenius, Marissa K Caldow, Justin P Hardee, Peter J Crouch, Scott Ayton, Ashley I Bush, Gordon S Lynch, Rene Koopman

Journal article  |  2021  |  Journal of Cachexia Sarcopenia and Muscle

BACKGROUND: Oxidative stress is implicated in the insidious loss of muscle mass and strength that occurs with age. However, few st..

Metabolic remodeling of dystrophic skeletal muscle reveals biological roles for dystrophin and utrophin in adaptation and plasticity.

Justin P Hardee, Karen JB Martins, Paula M Miotto, James G Ryall, Stefan M Gehrig, Boris Reljic, Timur Naim, Jin D Chung, Jen Trieu, Kristy Swiderski, Ashleigh M Philp, Andrew Philp, Matthew J Watt, David A Stroud, Rene Koopman, Gregory R Steinberg, Gordon S Lynch

Journal article  |  2021  |  Molecular Metabolism

OBJECTIVES: Preferential damage to fast, glycolytic myofibers is common in many muscle-wasting diseases, including Duchenne muscul..

Distinct roles for dietary protein and amino acids in health and disease

Rene Koopman, Rajavel Elango

Journal article  |  2021  |  Current Opinion in Clinical Nutrition & Metabolic Care

Functional electrical stimulation in-bed cycle ergometry in mechanically ventilated patients: a multicentre randomised controlled trial.

Sue Berney, Ramona O Hopkins, Joleen Wyn Rose, Rene Koopman, Zudin Puthucheary, Amy Pastva, Ian Gordon, Elizabeth Colantuoni, Selina M Parry, Dale M Needham, Linda Denehy

Journal article  |  2020  |  Thorax

PURPOSE: To investigate the effect of functional electrical stimulation-assisted cycle ergometry (FES-cycling) on muscle strength,..

Protein Type, Protein Dose, and Age Modulate Dietary Protein Digestion and Phenylalanine Absorption Kinetics and Plasma Phenylalanine Availability in Humans

Stefan HM Gorissen, Jorn Trommelen, Imre WK Kouw, Andrew M Holwerda, Bart Pennings, Bart BL Groen, Benjamin T Wall, Tyler A Churchward-Venne, Astrid MH Horstman, Rene Koopman, Nicholas A Burd, Cas J Fuchs, Marlou L Dirks, Peter T Res, Joan MG Senden, Jan MJM Steijns, Lisette CPGM de Groot, Lex B Verdijk, Luc JC van Loon

Journal article  |  2020  |  The Journal of Nutrition

Spatiotemporal Mapping Reveals Regional Gastrointestinal Dysfunction in mdx Dystrophic Mice Ameliorated by Oral L-arginine Supplementation

Kristy Swiderski, Rebecka Bindon, Jennifer Trieu, Timur Naim, Shana Schokman, Mathusi Swaminathan, Anita JL Leembruggen, Elisa L Hill-Yardin, Rene Koopman, Joel C Bornstein, Gordon S Lynch

Journal article  |  2020  |  Journal of Neurogastroenterology and Motility

Background/Aims: Patients with Duchenne muscular dystrophy exhibit significant, ongoing impairments in gastrointestinal (GI) funct..

Glycine Protects Muscle Cells From Wasting in vitro via mTORC1 Signaling

Marissa K Caldow, Daniel J Ham, Jennifer Trieu, Jin Dylan Chung, Gordon S Lynch, Rene Koopman

Journal article  |  2019  |  FRONTIERS IN NUTRITION

Glycine administration attenuates progression of dystrophic pathology in prednisolone-treated dystrophin/utrophin null mice

Daniel J Ham, Anastasia Gardner, Tahnee L Kennedy, Jennifer Trieu, Timur Naim, Annabel Chee, Francesca M Alves, Marissa K Caldow, Gordon S Lynch, Rene Koopman

Journal article  |  2019  |  Scientific Reports

Choline administration attenuates aspects of the dystrophic pathology in mdx mice

FM Alves, MK Caldow, J Trieu, T Naim, MK Montgomery, MJ Watt, GS Lynch, R Koopman

Journal article  |  2019  |  Clinical Nutrition Experimental

Deletion of suppressor of cytokine signaling 3 (SOCS3) in muscle stem cells does not alter muscle regeneration in mice after injury

Kristy Swiderski, Marissa K Caldow, Timur Naim, Jennifer Trieu, Annabel Chee, Rene Koopman, Gordon S Lynch

Journal article  |  2019  |  PLoS One