Elly Tchoubrieva

Cell cycle and growth stimuli regulate different steps of RNA polymerase I transcription

Sandy S Hung, Analia Lesmana, Abigail Peck, Rachel Lee, Elly Tchoubrieva, Katherine M Hannan, Jane Lin, Karen E Sheppard, Katarzyna Jastrzebski, Leonie M Quinn, Lawrence I Rothblum, Richard B Pearson, Ross D Hannan, Elaine Sanij

Journal article  |  2017  |  GENE

Transcription of the ribosomal RNA genes (rDNA) by RNA polymerase I (Pol I) is a major control step for ribosome synthesis and is ..

S6 Kinase is essential for MYC-dependent rDNA transcription in Drosophila

Naomi C Mitchell, Elissaveta B Tchoubrieva, Arjun Chahal, Simone Woods, Amanda Lee, Jane I Lin, Linda Parsons, Katarzyna Jastrzebski, Gretchen Poortinga, Katherine M Hannan, Richard B Pearson, Ross D Hannan, Leonie M Quinn

Journal article  |  2015  |  CELLULAR SIGNALLING

Increased rates of ribosome biogenesis and biomass accumulation are fundamental properties of rapidly growing and dividing maligna..

Drosophila Ribosomal Protein Mutants Control Tissue Growth Non-Autonomously via Effects on the Prothoracic Gland and Ecdysone

Jane I Lin, Naomi C Mitchell, Marina Kalcina, Elly Tchoubrieva, Mary J Stewart, Steven J Marygold, Cherryl D Walker, George Thomas, Sally J Leevers, Richard B Pearson, Leonie M Quinn, Ross D Hannan

Journal article  |  2011  |  PLOS GENETICS

The ribosome is critical for all aspects of cell growth due to its essential role in protein synthesis. Paradoxically, many Riboso..

Discovery and molecular characterization of a Bcl-2-regulated cell death pathway in schistosomes

Erinna F Lee, Oliver B Clarke, Marco Evangelista, Zhiping Feng, Terence P Speed, Elissaveta B Tchoubrieva, Andreas Strasser, Bernd H Kalinna, Peter M Colman, W Douglas Fairlie

Journal article  |  2011  |  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Schistosomiasis is an infectious disease caused by parasites of the phylum platyhelminthe. Here, we describe the identification an..

Vector-based RNA interference of cathepsin B1 in Schistosoma mansoni

Elissaveta B Tchoubrieva, Poh C Ong, Robert N Pike, Paul J Brindley, Bernd H Kalinna

Journal article  |  2010  |  CELLULAR AND MOLECULAR LIFE SCIENCES

In helminth parasites, proteolytic enzymes have been implicated in facilitating host invasion, moulting, feeding, and evasion of t..

Advances in mRNA silencing and transgene expression: a gateway to functional genomics in schistosomes

E TCHOUBRIEVA, B KALINNA

Journal article  |  2009  |  Biotechnology and Genetic Engineering Reviews

Conserved (CT)n.(GA)n repeats in the non-coding regions at the Gpdh locus are binding sites for the GAGA factor in drosophila melanogaster and its sibling species.

EB Tchoubrieva, JB Gibson

Journal article  |  2004  |  Genetica

The (CT)n.(GA)n rich sequences in the upstream and 5' intron enhancer regions of the sn-glycerol-3-phosphate dehydrogenase (Gpdh) ..