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A/Prof

Justine Mintern

Associate Professor
Biochemistry And Molecular Biology
Immunity
Dendritic Cells
Vaccines
T Cells
Immunotherapy
Immunology
Infection
Antigen Presentation
Justine Mintern's Profile Picture
A/Prof

Justine Mintern

 
Division
Medicine, Dentistry And Health Sciences
 
Primary Interest
Cell biology
Justine Mintern's Profile Picture
A/Prof

Justine Mintern

 
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Justine's  Short Profile
 

Projects

Displaying the 10 most recent projects by Justine Mintern.

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Trafficking inside the cell for effective immunity.

This project aims to investigate how cargo is trafficked to the right destination inside cells. The project will investigate the trafficking..

2019 - 2022
Active
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Novel tools and nanotechnology to navigate intracellular trafficking.

This project aims to investigate how material accesses different compartments inside cells, also known as trafficking. Using immunology, cel..

2019 - 2023
Active
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Novel tools and nanotechnology to navigate intracellular trafficking.

This project aims to investigate how material accesses different compartments inside cells, also known as trafficking. Using immunology, cel..

2019 - 2023
Active
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MARCH UBIQUITIN LIGASES IN IMMUNITY AND INFECTION.

2019 - 2021
Active
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Pharmacokinetics and pharmacodynamics of human immunoglobulin G

2018
Active
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ENGINEERING THE TRAFFICKING OF NANOPARTICLES WITHIN CELLS

This project aims to engineer responsive nanoparticles capable of trafficking efficiently within cells. The site of release of therapeutic c..

2018 - 2020
Active
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THE CELL BIOLOGY OF THE ALBUMIN-FCRN RECEPTOR RECYCLING SYSTEM

The aim of this project is to define the cell biology of the albumin-FcRn (neonatal Fc receptor) recycling system. FcRn is a recycling membr..

2017 - 2020
Active
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THE CELL BIOLOGY OF THE ALBUMIN-FCRN RECEPTOR RECYCLING SYSTEM

The aim of this project is to define the cell biology of the albumin-FcRn (neonatal Fc receptor) recycling system. FcRn is a recycling membr..

2017 - 2020
Active
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IMPROVING THERAPEUTIC DELIVERY BY UNDERSTANDING NANOPARTICLE INTERACTIONS WITH CELLS

Nanotechnology has the potential to transform the way we treat many diseases. This project will investigate how nanoengineered particles can..

2017 - 2019
Completed
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IMPROVING THERAPEUTIC DELIVERY BY UNDERSTANDING NANOPARTICLE INTERACTIONS WITH CELLS

Nanotechnology has the potential to transform the way we treat many diseases. This project will investigate how nanoengineered particles can..

2017 - 2019
Completed

23

Projects

Project Types

16

Research Grant

5

Internal Research Grant

2

Research Contracts

Scholarly Works

Displaying the 10 most recent scholarly works by Justine Mintern.

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Endoplasmic reticulum chaperones stabilize ligand-receptive MR1 molecules for efficient presentation of metabolite antigens

Hamish EG McWilliam, Jeffrey YW Mak, Wael Awad, Matthew Zorkau, Sebastian Cruz-Gomez, Hui Jing Lim, Yuting Yan, Sam Wormald, Laura F Dagley, Sidonia BG Eckle, Alexandra J Corbett, Haiyin Liu, Shihan Li, Scott JJ Reddiex, Justine D Mintern, Ligong Liu, James McCluskey, Jamie Rossjohn, David P Fairlie, Jose A Villadangos

Journal article  |  2020  |  Proceedings of the National Academy of Sciences

The antigen-presenting molecule MR1 (MHC class I-related protein 1) presents metabolite antigens derived from microbial vitamin B2..

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Ubiquitination of MHC Class II Is Required for Development of Regulatory but Not Conventional CD4( ) T Cells

Haiyin Liu, Kayla R Wilson, Patrick Schriek, Christophe Macri, Annabelle B Blum, Lauren Francis, Melanie Heinlein, Champa Nataraja, James Harris, Sarah A Jones, Daniel HD Gray, Jose A Villadangos, Justine D Mintern

Journal article  |  2020  |  The Journal of Immunology

MHC class II (MHC II) displays peptides at the cell surface, a process critical for CD4+ T cell development and priming. Ubiquitin..

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Macropinocytosis in Different Cell Types: Similarities and Differences

Xiao Peng Lin, Justine D Mintern, Paul A Gleeson

Journal article  |  2020  |  Membranes

Macropinocytosis is a unique pathway of endocytosis characterised by the nonspecific internalisation of large amounts of extracell..

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COVID-19: searching for clues among other respiratory viruses

Catriona Nguyen-Robertson, Ashraful Haque, Justine Mintern, Anne C La Flamme

Journal article  |  2020  |  Immunology & Cell Biology

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The amalgamation of cellular metabolism and immunology for host immunity

Justine D Mintern, Katrina J Binger

Journal article  |  2020  |  Clinical and Translational Immunology

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Covalent binding of complement C3 to MHC-II mediates trogocytosis between conventional dendritic cells and MZ B cells in the spleen

P Schriek, JA Villadangos, JD Mintern

Conference Proceedings  |  2019  |  EUROPEAN JOURNAL OF IMMUNOLOGY

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Editorial overview: New proteins, cellular processes and intercellular interactions involved in antigen presentation

Justine D Mintern, Jose A Villadangos

Journal article  |  2019  |  Current Opinion in Immunology

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MARCH ligases in immunity

Haiyin Liu, Justine D Mintern, Jose A Villadangos

Journal article  |  2019  |  Current Opinion in Immunology

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Downregulation of MHC Class I Expression by Influenza A and B Viruses

Marios Koutsakos, Hamish EG McWilliam, Turgut E Aktepe, Svenja Fritzlar, Patricia T Illing, Nicole A Mifsud, Anthony W Purcell, Steve Rockman, Patrick C Reading, Julian P Vivian, Jamie Rossjohn, Andrew G Brooks, Jason M Mackenzie, Justine D Mintern, Jose A Villadangos, Thi HO Nguyen, Katherine Kedzierska

Journal article  |  2019  |  Frontiers in Immunology

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Dendritic Cells and Cancer: From Biology to Therapeutic Intervention

Ben Wylie, Christophe Macri, Justine D Mintern, Jason Waithman

Journal article  |  2019  |  Cancers

91

Scholarly Works

Keyword Analysis

Immunology
Biochemistry and Cell Biology
Clinical Health (organs, Diseases and Abnormal Conditions)
Expanding Knowledge
Clinical (organs, Diseases and Abnormal Conditions)
Other Health
Medical Microbiology
Oncology and Carcinogenesis
Medical Biochemistry and Metabolomics
Cardiovascular Medicine and Haematology

Honours, Awards and Fellowships

2010

NHMRCF - NHMRC Fellowship

2003

CJMARTIN - C.J. Martin Research Fellowship (National Health & Medical Research Council, Australia)

2

Awards

Credentials

Positions

Associate Professor

Biochemistry And Molecular Biology

Full

American Society of Immunology

Full

Australian and New Zealand Society for Cell and Developmental Biology

Full

Australian Society for Biochemistry and Molecular Biology

Education

Medical Biology

University of Melbourne

Bachelor of Science (honours)

University of Melbourne

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