Justine Mintern

Targeted delivery of mycophenolic acid to the mesenteric lymph node using a triglyceride mimetic prodrug approach enhances gut-specific immunomodulation in mice.

Ruby Kochappan, Enyuan Cao, Sifei Han, Luojuan Hu, Tim Quach, Danielle Senyschyn, Vilena Ivanova Ferreira, Given Lee, Nathania Leong, Garima Sharma, Shea Fern Lim, Cameron J Nowell, Ziqi Chen, Ulrich H von Andrian, Daniel Bonner, Justine D Mintern, Jamie S Simpson, Natalie L Trevaskis, Christopher JH Porter

Journal article  |  2021  |  Journal of Controlled Release

The mesenteric lymph nodes (MLN) are a key site for the generation of adaptive immune responses to gut-derived antigenic material ..

RNF41 regulates the damage recognition receptor Clec9A and antigen cross-presentation in mouse dendritic cells

Kirsteen M Tullett, Peck Szee Tan, Hae-Young Park, Ralf B Schittenhelm, Nicole Michael, Rong Li, Antonia N Policheni, Emily Gruber, Cheng Huang, Alex J Fulcher, Jillian C Danne, Peter E Czabotar, Linda M Wakim, Justine D Mintern, Georg Ramm, Kristen J Radford, Irina Caminschi, Meredith O'Keeffe, Jose A Villadangos, Mark D Wright, et al.

Journal article  |  2020  |  eLife

The dendritic cell receptor Clec9A facilitates processing of dead cell-derived antigens for cross-presentation and the induction o..

Endoplasmic reticulum chaperones stabilize ligand-receptive MR1 molecules for efficient presentation of metabolite antigens

Hamish EG McWilliam, Jeffrey YW Mak, Wael Awad, Matthew Zorkau, Sebastian Cruz-Gomez, Hui Jing Lim, Yuting Yan, Sam Wormald, Laura F Dagley, Sidonia BG Eckle, Alexandra J Corbett, Haiyin Liu, Shihan Li, Scott JJ Reddiex, Justine D Mintern, Ligong Liu, James McCluskey, Jamie Rossjohn, David P Fairlie, Jose A Villadangos

Journal article  |  2020  |  Proceedings of the National Academy of Sciences of USA

The antigen-presenting molecule MR1 (MHC class I-related protein 1) presents metabolite antigens derived from microbial vitamin B2..

Ubiquitination of MHC Class II Is Required for Development of Regulatory but Not Conventional CD4( ) T Cells

Haiyin Liu, Kayla R Wilson, Patrick Schriek, Christophe Macri, Annabelle B Blum, Lauren Francis, Melanie Heinlein, Champa Nataraja, James Harris, Sarah A Jones, Daniel HD Gray, Jose A Villadangos, Justine D Mintern

Journal article  |  2020  |  The Journal of Immunology

MHC class II (MHC II) displays peptides at the cell surface, a process critical for CD4+ T cell development and priming. Ubiquitin..

Macropinocytosis in Different Cell Types: Similarities and Differences

Xiao Peng Lin, Justine D Mintern, Paul A Gleeson

Journal article  |  2020  |  Membranes

Macropinocytosis is a unique pathway of endocytosis characterised by the nonspecific internalisation of large amounts of extracell..

COVID-19: searching for clues among other respiratory viruses

Catriona Nguyen-Robertson, Ashraful Haque, Justine Mintern, Anne C La Flamme

Journal article  |  2020  |  Immunology and Cell Biology

The amalgamation of cellular metabolism and immunology for host immunity

Justine D Mintern, Katrina J Binger

Journal article  |  2020  |  Clinical and Translational Immunology

Covalent binding of complement C3 to MHC-II mediates trogocytosis between conventional dendritic cells and MZ B cells in the spleen

P Schriek, JA Villadangos, JD Mintern

Conference Proceedings  |  2019  |  EUROPEAN JOURNAL OF IMMUNOLOGY

Editorial overview: New proteins, cellular processes and intercellular interactions involved in antigen presentation

Justine D Mintern, Jose A Villadangos

Journal article  |  2019  |  Current Opinion in Immunology

MARCH ligases in immunity

Haiyin Liu, Justine D Mintern, Jose A Villadangos

Journal article  |  2019  |  Current Opinion in Immunology